{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T04:42:45Z","timestamp":1769316165047,"version":"3.49.0"},"publisher-location":"Singapore","reference-count":110,"publisher":"Springer Singapore","isbn-type":[{"value":"9789811055614","type":"print"},{"value":"9789811055621","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"DOI":"10.1007\/978-981-10-5562-1_3","type":"book-chapter","created":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T08:59:07Z","timestamp":1509613147000},"page":"45-58","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Similarities and Differences in Neurobiology"],"prefix":"10.1007","author":[{"given":"Manli","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,11,3]]},"reference":[{"key":"3_CR1","first-page":"CD006306","volume":"3","author":"L Amato","year":"2007","unstructured":"Amato L, Minozzi S, Pani PP, Davoli M (2007) Antipsychotic medications for cocaine dependence. Cochrane Database Syst Rev 3:CD006306","journal-title":"Cochrane Database Syst Rev"},{"key":"3_CR2","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1196\/annals.1300.023","volume":"1003","author":"DA Baker","year":"2003","unstructured":"Baker DA, McFarland K, Lake RW, Shen H, Toda S, Kalivas PW (2003) N-acetyl cysteine-induced blockade of cocaine-induced reinstatement. Ann N Y Acad Sci 1003:349\u2013351","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"3_CR3","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00213-006-0521-1","volume":"191","author":"MF Barbano","year":"2007","unstructured":"Barbano MF, Cador M (2007) Opioids for hedonic experience and dopamine to get ready for it. Psychopharmacology 191(3):497\u2013506","journal-title":"Psychopharmacology"},{"issue":"5","key":"3_CR4","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1111\/add.12066","volume":"108","author":"I Boileau","year":"2013","unstructured":"Boileau I, Payer D, Chugani B, Lobo D, Behzadi A, Rusjan PM, Houle S, Wilson AA, Warsh J, Kish SJ, Zack M (2013) The D2\/3 dopamine receptor in pathological gambling: a positron emission tomography study with [11C]-(+)-propyl-hexahydro-naphtho-oxazin and [11C]raclopride. Addiction 108(5):953\u2013963","journal-title":"Addiction"},{"issue":"12","key":"3_CR5","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1038\/mp.2013.163","volume":"19","author":"I Boileau","year":"2014","unstructured":"Boileau I, Payer D, Chugani B, Lobo DS, Houle S, Wilson AA, Warsh J, Kish SJ, Zack M (2014) In vivo evidence for greater amphetamine-induced dopamine release in pathological gambling: a positron emission tomography study with [(11)C]-(+)-PHNO. Mol Psychiatry 19(12):1305\u20131313","journal-title":"Mol Psychiatry"},{"issue":"1","key":"3_CR6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.bcp.2007.06.043","volume":"75","author":"JA Brewer","year":"2008","unstructured":"Brewer JA, Potenza MN (2008) The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol 75(1):63\u201375","journal-title":"Biochem Pharmacol"},{"issue":"1","key":"3_CR7","doi-asserted-by":"crossref","first-page":"67","DOI":"10.2174\/2211557911201010067","volume":"1","author":"SA Bullock","year":"2012","unstructured":"Bullock SA, Potenza MN (2012) Pathological gambling: neuropsychopharmacology and treatment. Curr Psychopharmacol 1(1):67\u201385","journal-title":"Curr Psychopharmacol"},{"issue":"2","key":"3_CR8","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/npp.2010.170","volume":"36","author":"D Campbell-Meiklejohn","year":"2011","unstructured":"Campbell-Meiklejohn D, Wakeley J, Herbert V, Cook J, Scollo P, Ray MK, Selvaraj S, Passingham RE, Cowen P, Rogers RD (2011) Serotonin and dopamine play complementary roles in gambling to recover losses. Neuropsychopharmacology 36(2):402\u2013410","journal-title":"Neuropsychopharmacology"},{"issue":"5","key":"3_CR9","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1046\/j.1360-0443.1998.9357137.x","volume":"93","author":"KM Carroll","year":"1998","unstructured":"Carroll KM, Nich C, Ball SA, McCance E, Rounsavile BJ (1998) Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram. Addiction 93(5):713\u2013727","journal-title":"Addiction"},{"issue":"3","key":"3_CR10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1001\/archpsyc.61.3.264","volume":"61","author":"KM Carroll","year":"2004","unstructured":"Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ (2004) Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial. Arch Gen Psychiatry 61(3):264\u2013272","journal-title":"Arch Gen Psychiatry"},{"issue":"1","key":"3_CR11","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.neuroimage.2012.06.067","volume":"63","author":"L Clark","year":"2012","unstructured":"Clark L, Stokes PR, Wu K, Michalczuk R, Benecke A, Watson BJ, Egerton A, Piccini P, Nutt DJ, Bowden-Jones H, Lingford-Hughes AR (2012) Striatal dopamine D(2)\/D(3) receptor binding in pathological gambling is correlated with mood-related impulsivity. NeuroImage 63(1):40\u201346","journal-title":"NeuroImage"},{"issue":"45","key":"3_CR12","doi-asserted-by":"crossref","first-page":"17617","DOI":"10.1523\/JNEUROSCI.3231-13.2013","volume":"33","author":"L Clark","year":"2013","unstructured":"Clark L, Averbeck B, Payer D, Sescousse G, Winstanley CA, Xue G (2013) Pathological choice: the neuroscience of gambling and gambling addiction. J Neurosci 33(45):17617\u201317623","journal-title":"J Neurosci"},{"issue":"2","key":"3_CR13","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0166-4328(02)00132-8","volume":"136","author":"J Crean","year":"2002","unstructured":"Crean J, Richards JB, de Wit H (2002) Effect of tryptophan depletion on impulsive behavior in men with or without a family history of alcoholism. Behav Brain Res 136(2):349\u2013357","journal-title":"Behav Brain Res"},{"issue":"1","key":"3_CR14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0893-133X(01)00293-7","volume":"26","author":"TJ Vries De","year":"2002","unstructured":"De Vries TJ, Schoffelmeer AN, Binnekade R, Raaso H, Vanderschuren LJ (2002) Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. Neuropsychopharmacology 26(1):18\u201326","journal-title":"Neuropsychopharmacology"},{"issue":"7","key":"3_CR15","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1523\/JNEUROSCI.22-07-02873.2002","volume":"22","author":"C Drouin","year":"2002","unstructured":"Drouin C, Darracq L, Trovero F, Blanc G, Glowinski J, Cotecchia S, Tassin JP (2002) Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates. J Neurosci 22(7):2873\u20132884","journal-title":"J Neurosci"},{"issue":"2","key":"3_CR16","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0893-133X(99)00158-X","volume":"23","author":"S Erb","year":"2000","unstructured":"Erb S, Hitchcott PK, Rajabi H, Mueller D, Shaham Y, Stewart J (2000) Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seeking. Neuropsychopharmacology 23(2):138\u2013150","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"3_CR17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1001\/archpsyc.1996.01830030029006","volume":"53","author":"ML Fils-Aime","year":"1996","unstructured":"Fils-Aime ML, Eckardt MJ, George DT, Brown GL, Mefford I, Linnoila M (1996) Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. Arch Gen Psychiatry 53(3):211\u2013216","journal-title":"Arch Gen Psychiatry"},{"issue":"3","key":"3_CR18","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.pbb.2007.12.025","volume":"89","author":"T Fong","year":"2008","unstructured":"Fong T, Kalechstein A, Bernhard B, Rosenthal R, Rugle L (2008) A double-blind, placebo-controlled trial of olanzapine for the treatment of video poker pathological gamblers. Pharmacol Biochem Behav 89(3):298\u2013303","journal-title":"Pharmacol Biochem Behav"},{"issue":"12","key":"3_CR19","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/S0006-3223(99)00310-8","volume":"47","author":"TP George","year":"2000","unstructured":"George TP, Chawarski MC, Pakes J, Carroll KM, Kosten TR, Schottenfeld RS (2000) Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial. Biol Psychiatry 47(12):1080\u20131086","journal-title":"Biol Psychiatry"},{"issue":"10","key":"3_CR20","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1176\/appi.ajp.159.10.1642","volume":"159","author":"RZ Goldstein","year":"2002","unstructured":"Goldstein RZ, Volkow ND (2002) Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry 159(10):1642\u20131652","journal-title":"Am J Psychiatry"},{"issue":"2","key":"3_CR21","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.neubiorev.2004.03.001","volume":"28","author":"AE Goudriaan","year":"2004","unstructured":"Goudriaan AE, Oosterlaan J, de Beurs E, Van den Brink W (2004) Pathological gambling: a comprehensive review of biobehavioral findings. Neurosci Biobehav Rev 28(2):123\u2013141","journal-title":"Neurosci Biobehav Rev"},{"issue":"4","key":"3_CR22","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00004850-200307000-00007","volume":"18","author":"JE Grant","year":"2003","unstructured":"Grant JE, Kim SW, Potenza MN, Blanco C, Ibanez A, Stevens L, Hektner JM, Zaninelli R (2003) Paroxetine treatment of pathological gambling: a multi-centre randomized controlled trial. Int Clin Psychopharmacol 18(4):243\u2013249","journal-title":"Int Clin Psychopharmacol"},{"issue":"2","key":"3_CR23","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1176\/appi.ajp.163.2.303","volume":"163","author":"JE Grant","year":"2006","unstructured":"Grant JE, Potenza MN, Hollander E, Cunningham-Williams R, Nurminen T, Smits G, Kallio A (2006) Multicenter investigation of the opioid antagonist nalmefene in the treatment of pathological gambling. Am J Psychiatry 163(2):303\u2013312","journal-title":"Am J Psychiatry"},{"issue":"6","key":"3_CR24","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.biopsych.2006.11.021","volume":"62","author":"JE Grant","year":"2007","unstructured":"Grant JE, Kim SW, Odlaug BL (2007) N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol Psychiatry 62(6):652\u2013657","journal-title":"Biol Psychiatry"},{"issue":"4","key":"3_CR25","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00213-008-1235-3","volume":"200","author":"JE Grant","year":"2008","unstructured":"Grant JE, Kim SW, Hollander E, Potenza MN (2008) Predicting response to opiate antagonists and placebo in the treatment of pathological gambling. Psychopharmacology (Berl) 200(4):521\u2013527","journal-title":"Psychopharmacology (Berl)"},{"issue":"5","key":"3_CR26","doi-asserted-by":"crossref","first-page":"783","DOI":"10.4088\/JCP.v69n0511","volume":"69","author":"JE Grant","year":"2008","unstructured":"Grant JE, Kim SW, Hartman BK (2008a) A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges. J Clin Psychiatry 69(5):783\u2013789","journal-title":"J Clin Psychiatry"},{"issue":"4","key":"3_CR27","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s00213-010-1994-5","volume":"212","author":"JE Grant","year":"2010","unstructured":"Grant JE, Chamberlain SR, Odlaug BL, Potenza MN, Kim SW (2010) Memantine shows promise in reducing gambling severity and cognitive inflexibility in pathological gambling: a pilot study. Psychopharmacology 212(4):603\u2013612","journal-title":"Psychopharmacology"},{"issue":"4","key":"3_CR28","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1192\/bjp.bp.110.078105","volume":"197","author":"JE Grant","year":"2010","unstructured":"Grant JE, Odlaug BL, Potenza MN, Hollander E, Kim SW (2010) Nalmefene in the treatment of pathological gambling: multicentre, double-blind, placebo-controlled study. Br J Psychiatry 197(4):330\u2013331","journal-title":"Br J Psychiatry"},{"issue":"2","key":"3_CR29","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1521-0391.2009.00027.x","volume":"19","author":"KM Gray","year":"2010","unstructured":"Gray KM, Watson NL, Carpenter MJ, Larowe SD (2010) N-acetylcysteine (NAC) in young marijuana users: an open-label pilot study. Am J Addict 19(2):187\u2013189","journal-title":"Am J Addict"},{"issue":"5","key":"3_CR30","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1097\/01.ALC.0000125352.06688.F7","volume":"28","author":"J Guardia","year":"2004","unstructured":"Guardia J, Segura L, Gonzalvo B, Iglesias L, Roncero C, Cardus M, Casas M (2004) A double-blind, placebo-controlled study of olanzapine in the treatment of alcohol-dependence disorder. Alcohol Clin Exp Res 28(5):736\u2013745","journal-title":"Alcohol Clin Exp Res"},{"issue":"10","key":"3_CR31","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1176\/ajp.161.10.1783","volume":"161","author":"A Heinz","year":"2004","unstructured":"Heinz A, Siessmeier T, Wrase J, Hermann D, Klein S, Grusser SM, Flor H, Braus DF, Buchholz HG, Grunder G, Schreckenberger M, Smolka MN, Rosch F, Mann K, Bartenstein P (2004) Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. Am J Psychiatry 161(10):1783\u20131789","journal-title":"Am J Psychiatry"},{"issue":"2","key":"3_CR32","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s002130050169","volume":"129","author":"A Herz","year":"1997","unstructured":"Herz A (1997) Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berl) 129(2):99\u2013111","journal-title":"Psychopharmacology (Berl)"},{"issue":"3","key":"3_CR33","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF02245330","volume":"116","author":"J Hietala","year":"1994","unstructured":"Hietala J, West C, Syvalahti E, Nagren K, Lehikoinen P, Sonninen P, Ruotsalainen U (1994) Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence. Psychopharmacology (Berl) 116(3):285\u2013290","journal-title":"Psychopharmacology (Berl)"},{"issue":"3","key":"3_CR34","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S0893-133X(01)00227-5","volume":"25","author":"D Highfield","year":"2001","unstructured":"Highfield D, Yap J, Grimm JW, Shalev U, Shaham Y (2001) Repeated lofexidine treatment attenuates stress-induced, but not drug cues-induced reinstatement of a heroin-cocaine mixture (speedball) seeking in rats. Neuropsychopharmacology 25(3):320\u2013331","journal-title":"Neuropsychopharmacology"},{"issue":"9","key":"3_CR35","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0006-3223(00)00241-9","volume":"47","author":"E Hollander","year":"2000","unstructured":"Hollander E, DeCaria CM, Finkell JN, Begaz T, Wong CM, Cartwright C (2000) A randomized double-blind fluvoxamine\/placebo crossover trial in pathologic gambling. Biol Psychiatry 47(9):813\u2013817","journal-title":"Biol Psychiatry"},{"issue":"9","key":"3_CR36","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.biopsych.2009.12.028","volume":"67","author":"J Hu","year":"2010","unstructured":"Hu J, Henry S, Gallezot JD, Ropchan J, Neumaier JF, Potenza MN, Sinha R, Krystal JH, Huang Y, Ding YS, Carson RE, Neumeister A (2010) Serotonin 1B receptor imaging in alcohol dependence. Biol Psychiatry 67(9):800\u2013803","journal-title":"Biol Psychiatry"},{"issue":"1","key":"3_CR37","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00213-011-2230-7","volume":"218","author":"ML Jobes","year":"2011","unstructured":"Jobes ML, Ghitza UE, Epstein DH, Phillips KA, Heishman SJ, Preston KL (2011) Clonidine blocks stress-induced craving in cocaine users. Psychopharmacology (Berl) 218(1):83\u201388","journal-title":"Psychopharmacology (Berl)"},{"issue":"3","key":"3_CR38","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1176\/appi.ajp.158.3.349","volume":"158","author":"PW Kalivas","year":"2001","unstructured":"Kalivas PW (2001) Drug addiction: to the cortex and beyond! Am J Psychiatry 158(3):349\u2013350","journal-title":"Am J Psychiatry"},{"issue":"8","key":"3_CR39","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/nrn2515","volume":"10","author":"PW Kalivas","year":"2009","unstructured":"Kalivas PW (2009) The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci 10(8):561\u2013572","journal-title":"Nat Rev Neurosci"},{"issue":"10","key":"3_CR40","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1038\/mp.2011.46","volume":"16","author":"PW Kalivas","year":"2011","unstructured":"Kalivas PW, Volkow ND (2011) New medications for drug addiction hiding in glutamatergic neuroplasticity. Mol Psychiatry 16(10):974\u2013986","journal-title":"Mol Psychiatry"},{"issue":"2","key":"3_CR41","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/S0022-3565(24)39122-0","volume":"294","author":"TV Khroyan","year":"2000","unstructured":"Khroyan TV, Barrett-Larimore RL, Rowlett JK, Spealman RD (2000) Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. J Pharmacol Exp Ther 294(2):680\u2013687","journal-title":"J Pharmacol Exp Ther"},{"issue":"11","key":"3_CR42","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S0006-3223(01)01079-4","volume":"49","author":"SW Kim","year":"2001","unstructured":"Kim SW, Grant JE, Adson DE, Shin YC (2001) Double-blind naltrexone and placebo comparison study in the treatment of pathological gambling. Biol Psychiatry 49(11):914\u2013921","journal-title":"Biol Psychiatry"},{"issue":"6","key":"3_CR43","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4088\/JCP.v63n0606","volume":"63","author":"SW Kim","year":"2002","unstructured":"Kim SW, Grant JE, Adson DE, Shin YC, Zaninelli R (2002) A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gambling. J Clin Psychiatry 63(6):501\u2013507","journal-title":"J Clin Psychiatry"},{"issue":"10","key":"3_CR44","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.biopsych.2008.10.040","volume":"65","author":"LA Knackstedt","year":"2009","unstructured":"Knackstedt LA, LaRowe S, Mardikian P, Malcolm R, Upadhyaya H, Hedden S, Markou A, Kalivas PW (2009) The role of cystine-glutamate exchange in nicotine dependence in rats and humans. Biol Psychiatry 65(10):841\u2013845","journal-title":"Biol Psychiatry"},{"issue":"5335","key":"3_CR45","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1126\/science.278.5335.52","volume":"278","author":"GF Koob","year":"1997","unstructured":"Koob GF, Le Moal M (1997) Drug abuse: hedonic homeostatic dysregulation. Science 278(5335):52\u201358","journal-title":"Science"},{"issue":"6","key":"3_CR46","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.biopsych.2006.11.018","volume":"62","author":"S Krishnan-Sarin","year":"2007","unstructured":"Krishnan-Sarin S, Krystal JH, Shi J, Pittman B, O'Malley SS (2007) Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking. Biol Psychiatry 62(6):694\u2013697","journal-title":"Biol Psychiatry"},{"issue":"3","key":"3_CR47","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1176\/ajp.2007.164.3.519","volume":"164","author":"EM Krupitsky","year":"2007","unstructured":"Krupitsky EM, Neznanova O, Masalov D, Burakov AM, Didenko T, Romanova T, Tsoy M, Bespalov A, Slavina TY, Grinenko AA, Petrakis IL, Pittman B, Gueorguieva R, Zvartau EE, Krystal JH (2007) Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients. Am J Psychiatry 164(3):519\u2013523","journal-title":"Am J Psychiatry"},{"issue":"11","key":"3_CR48","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1001\/archpsyc.1994.03950110058008","volume":"51","author":"JH Krystal","year":"1994","unstructured":"Krystal JH, Webb E, Cooney N, Kranzler HR, Charney DS (1994) Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms. Arch Gen Psychiatry 51(11):898\u2013911","journal-title":"Arch Gen Psychiatry"},{"issue":"47","key":"3_CR49","doi-asserted-by":"crossref","first-page":"14734","DOI":"10.1523\/JNEUROSCI.3765-09.2009","volume":"29","author":"B Lee","year":"2009","unstructured":"Lee B, London ED, Poldrack RA, Farahi J, Nacca A, Monterosso JR, Mumford JA, Bokarius AV, Dahlbom M, Mukherjee J, Bilder RM, Brody AL, Mandelkern MA (2009) Striatal dopamine d2\/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity. J Neurosci 29(47):14734\u201314740","journal-title":"J Neurosci"},{"issue":"11","key":"3_CR50","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1176\/ajp.156.11.1771","volume":"156","author":"DG LeMarquand","year":"1999","unstructured":"LeMarquand DG, Benkelfat C, Pihl RO, Palmour RM, Young SN (1999) Behavioral disinhibition induced by tryptophan depletion in nonalcoholic young men with multigenerational family histories of paternal alcoholism. Am J Psychiatry 156(11):1771\u20131779","journal-title":"Am J Psychiatry"},{"issue":"13","key":"3_CR51","doi-asserted-by":"crossref","first-page":"5713","DOI":"10.1523\/JNEUROSCI.22-13-05713.2002","volume":"22","author":"F Leri","year":"2002","unstructured":"Leri F, Flores J, Rodaros D, Stewart J (2002) Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala. J Neurosci 22(13):5713\u20135718","journal-title":"J Neurosci"},{"issue":"9","key":"3_CR52","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1111\/j.1360-0443.2009.02671.x","volume":"104","author":"DS Lobo","year":"2009","unstructured":"Lobo DS, Kennedy JL (2009) Genetic aspects of pathological gambling: a complex disorder with shared genetic vulnerabilities. Addiction 104(9):1454\u20131465","journal-title":"Addiction"},{"issue":"4","key":"3_CR53","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.conb.2013.02.005","volume":"23","author":"PE Lutz","year":"2013","unstructured":"Lutz PE, Kieffer BL (2013) The multiple facets of opioid receptor function: implications for addiction. Curr Opin Neurobiol 23(4):473\u2013479","journal-title":"Curr Opin Neurobiol"},{"issue":"1\u20132","key":"3_CR54","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1159\/000129665","volume":"57","author":"D Marazziti","year":"2008","unstructured":"Marazziti D, Golia F, Picchetti M, Pioli E, Mannari P, Lenzi F, Conversano C, Carmassi C, Catena Dell\u2019Osso M, Consoli G, Baroni S, Giannaccini G, Zanda G, Dell\u2019Osso L (2008) Decreased density of the platelet serotonin transporter in pathological gamblers. Neuropsychobiology 57(1\u20132):38\u201343","journal-title":"Neuropsychobiology"},{"issue":"10","key":"3_CR55","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.biopsych.2005.04.044","volume":"58","author":"D Martinez","year":"2005","unstructured":"Martinez D, Gil R, Slifstein M, Hwang DR, Huang Y, Perez A, Kegeles L, Talbot P, Evans S, Krystal J, Laruelle M, Abi-Dargham A (2005) Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biol Psychiatry 58(10):779\u2013786","journal-title":"Biol Psychiatry"},{"issue":"4","key":"3_CR56","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1176\/ajp.2007.164.4.622","volume":"164","author":"D Martinez","year":"2007","unstructured":"Martinez D, Narendran R, Foltin RW, Slifstein M, Hwang DR, Broft A, Huang Y, Cooper TB, Fischman MW, Kleber HD, Laruelle M (2007) Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. Am J Psychiatry 164(4):622\u2013629","journal-title":"Am J Psychiatry"},{"issue":"10","key":"3_CR57","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1176\/appi.ajp.2009.08121801","volume":"166","author":"D Martinez","year":"2009","unstructured":"Martinez D, Greene K, Broft A, Kumar D, Liu F, Narendran R, Slifstein M, Van Heertum R, Kleber HD (2009) Lower level of endogenous dopamine in patients with cocaine dependence: findings from PET imaging of D(2)\/D(3) receptors following acute dopamine depletion. Am J Psychiatry 166(10):1170\u20131177","journal-title":"Am J Psychiatry"},{"issue":"6","key":"3_CR58","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1176\/appi.ajp.2010.10050748","volume":"168","author":"D Martinez","year":"2011","unstructured":"Martinez D, Carpenter KM, Liu F, Slifstein M, Broft A, Friedman AC, Kumar D, Van Heertum R, Kleber HD, Nunes E (2011) Imaging dopamine transmission in cocaine dependence: link between neurochemistry and response to treatment. Am J Psychiatry 168(6):634\u2013641","journal-title":"Am J Psychiatry"},{"issue":"3","key":"3_CR59","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.biopsych.2011.08.024","volume":"71","author":"D Martinez","year":"2012","unstructured":"Martinez D, Saccone PA, Liu F, Slifstein M, Orlowska D, Grassetti A, Cook S, Broft A, Van Heertum R, Comer SD (2012) Deficits in dopamine D(2) receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types of addiction. Biol Psychiatry 71(3):192\u2013198","journal-title":"Biol Psychiatry"},{"issue":"3","key":"3_CR60","doi-asserted-by":"crossref","first-page":"433","DOI":"10.4088\/JCP.v69n0314","volume":"69","author":"SL McElroy","year":"2008","unstructured":"McElroy SL, Nelson EB, Welge JA, Kaehler L, Keck PE Jr (2008) Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trial. J Clin Psychiatry 69(3):433\u2013440","journal-title":"J Clin Psychiatry"},{"issue":"8","key":"3_CR61","first-page":"1386","volume":"23","author":"PM Monti","year":"1999","unstructured":"Monti PM, Rohsenow DJ, Hutchison KE, Swift RM, Mueller TI, Colby SM, Brown RA, Gulliver SB, Gordon A, Abrams DB (1999) Naltrexone\u2019s effect on cue-elicited craving among alcoholics in treatment. Alcohol Clin Exp Res 23(8):1386\u20131394","journal-title":"Alcohol Clin Exp Res"},{"key":"3_CR62","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1146\/annurev.ne.02.030179.000553","volume":"2","author":"RY Moore","year":"1979","unstructured":"Moore RY, Bloom FE (1979) Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. Annu Rev Neurosci 2:113\u2013168","journal-title":"Annu Rev Neurosci"},{"issue":"12","key":"3_CR63","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/syn.20970","volume":"65","author":"R Narendran","year":"2011","unstructured":"Narendran R, Martinez D, Mason NS, Lopresti BJ, Himes ML, Chen CM, May MA, Price JC, Mathis CA, Frankle WG (2011) Imaging of dopamine D2\/3 agonist binding in cocaine dependence: a [11C]NPA positron emission tomography study. Synapse 65(12):1344\u20131349","journal-title":"Synapse"},{"issue":"10","key":"3_CR64","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s40263-013-0096-4","volume":"27","author":"MJ Niciu","year":"2013","unstructured":"Niciu MJ, Arias AJ (2013) Targeted opioid receptor antagonists in the treatment of alcohol use disorders. CNS Drugs 27(10):777\u2013787","journal-title":"CNS Drugs"},{"issue":"12","key":"3_CR65","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1017\/S1092852900006799","volume":"4","author":"C Nordin","year":"1999","unstructured":"Nordin C, Eklundh T (1999) Altered CSF 5-HIAA disposition in pathologic male gamblers. CNS Spectr 4(12):25\u201333","journal-title":"CNS Spectr"},{"issue":"2\u20133","key":"3_CR66","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000115782","volume":"56","author":"C Nordin","year":"2007","unstructured":"Nordin C, Gupta RC, Sjodin I (2007) Cerebrospinal fluid amino acids in pathological gamblers and healthy controls. Neuropsychobiology 56(2\u20133):152\u2013158","journal-title":"Neuropsychobiology"},{"issue":"4","key":"3_CR67","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s10899-010-9219-8","volume":"27","author":"D Nussbaum","year":"2011","unstructured":"Nussbaum D, Honarmand K, Govoni R, Kalahani-Bargis M, Bass S, Ni X, Laforge K, Burden A, Romero K, Basarke S, Courbasson C, Deamond W (2011) An eight component decision-making model for problem gambling: a systems approach to stimulate integrative research. J Gambl Stud 27(4):523\u2013563","journal-title":"J Gambl Stud"},{"issue":"7","key":"3_CR68","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.neuropharm.2011.03.010","volume":"61","author":"CM Olsen","year":"2011","unstructured":"Olsen CM (2011) Natural rewards, neuroplasticity, and non-drug addictions. Neuropharmacology 61(7):1109\u20131122","journal-title":"Neuropharmacology"},{"issue":"8","key":"3_CR69","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S1471-4906(03)00173-X","volume":"24","author":"DA Padgett","year":"2003","unstructured":"Padgett DA, Glaser R (2003) How stress influences the immune response. Trends Immunol 24(8):444\u2013448","journal-title":"Trends Immunol"},{"issue":"3","key":"3_CR70","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1037\/1064-1297.7.3.266","volume":"7","author":"T Palfai","year":"1999","unstructured":"Palfai T, Davidson D, Swift R (1999) Influence of naltrexone on cue-elicited craving among hazardous drinkers: the moderational role of positive outcome expectancies. Exp Clin Psychopharmacol 7(3):266\u2013273","journal-title":"Exp Clin Psychopharmacol"},{"issue":"12","key":"3_CR71","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1017\/S1092852900015145","volume":"11","author":"S Pallanti","year":"2006","unstructured":"Pallanti S, Bernardi S, Quercioli L, DeCaria C, Hollander E (2006) Serotonin dysfunction in pathological gamblers: increased prolactin response to oral m-CPP versus placebo. CNS Spectr 11(12):956\u2013964","journal-title":"CNS Spectr"},{"issue":"6","key":"3_CR72","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1177\/0269881108099419","volume":"24","author":"S Pallanti","year":"2010","unstructured":"Pallanti S, Bernardi S, Allen A, Chaplin W, Watner D, DeCaria CM, Hollander E (2010) Noradrenergic function in pathological gambling: blunted growth hormone response to clonidine. J Psychopharmacol 24(6):847\u2013853","journal-title":"J Psychopharmacol"},{"issue":"6","key":"3_CR73","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1177\/1073858406293154","volume":"12","author":"S Pecina","year":"2006","unstructured":"Pecina S, Smith KS, Berridge KC (2006) Hedonic hot spots in the brain. Neuroscientist 12(6):500\u2013511","journal-title":"Neuroscientist"},{"issue":"5","key":"3_CR74","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1111\/ejn.12283","volume":"38","author":"CJ Perry","year":"2013","unstructured":"Perry CJ, McNally GP (2013) A role for the ventral pallidum in context-induced and primed reinstatement of alcohol seeking. Eur J Neurosci 38(5):2762\u20132773","journal-title":"Eur J Neurosci"},{"issue":"42","key":"3_CR75","doi-asserted-by":"crossref","first-page":"10509","DOI":"10.1523\/JNEUROSCI.2807-08.2008","volume":"28","author":"P Petrovic","year":"2008","unstructured":"Petrovic P, Pleger B, Seymour B, Kloppel S, De Martino B, Critchley H, Dolan RJ (2008) Blocking central opiate function modulates hedonic impact and anterior cingulate response to rewards and losses. J Neurosci 28(42):10509\u201310516","journal-title":"J Neurosci"},{"issue":"1507","key":"3_CR76","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1098\/rstb.2008.0100","volume":"363","author":"MN Potenza","year":"2008","unstructured":"Potenza MN (2008) Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond Ser B Biol Sci 363(1507):3181\u20133189","journal-title":"Philos Trans R Soc Lond Ser B Biol Sci"},{"issue":"9","key":"3_CR77","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1176\/appi.ajp.158.9.1500","volume":"158","author":"MN Potenza","year":"2001","unstructured":"Potenza MN, Steinberg MA, McLaughlin SD, Wu R, Rounsaville BJ, O\u2019Malley SS (2001) Gender-related differences in the characteristics of problem gamblers using a gambling helpline. Am J Psychiatry 158(9):1500\u20131505","journal-title":"Am J Psychiatry"},{"issue":"4","key":"3_CR78","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1176\/appi.ajp.2011.11020289","volume":"169","author":"MN Potenza","year":"2012","unstructured":"Potenza MN, Hong KI, Lacadie CM, Fulbright RK, Tuit KL, Sinha R (2012) Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence. Am J Psychiatry 169(4):406\u2013414","journal-title":"Am J Psychiatry"},{"issue":"2","key":"3_CR79","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3109\/15622975.2011.598559","volume":"14","author":"MN Potenza","year":"2013","unstructured":"Potenza MN, Walderhaug E, Henry S, Gallezot JD, Planeta-Wilson B, Ropchan J, Neumeister A (2013) Serotonin 1B receptor imaging in pathological gambling. World J Biol Psychiatry 14(2):139\u2013145","journal-title":"World J Biol Psychiatry"},{"issue":"6","key":"3_CR80","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/alcalc\/37.6.522","volume":"37","author":"JE Ratsma","year":"2002","unstructured":"Ratsma JE, Van Der Stelt O, Gunning WB (2002) Neurochemical markers of alcoholism vulnerability in humans. Alcohol Alcohol 37(6):522\u2013533","journal-title":"Alcohol Alcohol"},{"issue":"4819","key":"3_CR81","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1126\/science.2820058","volume":"237","author":"MC Ritz","year":"1987","unstructured":"Ritz MC, Lamb RJ, Goldberg SR, Kuhar MJ (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237(4819):1219\u20131223","journal-title":"Science"},{"key":"3_CR82","first-page":"Cd001867","volume":"12","author":"S Rosner","year":"2010","unstructured":"Rosner S, Hackl-Herrwerth A, Leucht S, Vecchi S, Srisurapanont M, Soyka M (2010) Opioid antagonists for alcohol dependence. Cochrane Database Syst Rev 12:Cd001867","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"3_CR83","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0165-1781(89)90155-8","volume":"30","author":"A Roy","year":"1989","unstructured":"Roy A, DeJong J, Ferraro T, Adinoff B, Gold P, Rubinow D, Linnoila M (1989) CSF GABA and neuropeptides in pathological gamblers and normal controls. Psychiatry Res 30(2):137\u2013144","journal-title":"Psychiatry Res"},{"issue":"1","key":"3_CR84","doi-asserted-by":"crossref","first-page":"28","DOI":"10.4088\/JCP.v66n0104","volume":"66","author":"J Saiz-Ruiz","year":"2005","unstructured":"Saiz-Ruiz J, Blanco C, Ibanez A, Masramon X, Gomez MM, Madrigal M, Diez T (2005) Sertraline treatment of pathological gambling: a pilot study. J Clin Psychiatry 66(1):28\u201333","journal-title":"J Clin Psychiatry"},{"issue":"1","key":"3_CR85","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0165-0173(00)00024-2","volume":"33","author":"Y Shaham","year":"2000","unstructured":"Shaham Y, Erb S, Stewart J (2000) Stress-induced relapse to heroin and cocaine seeking in rats: a review. Brain Res Brain Res Rev 33(1):13\u201333","journal-title":"Brain Res Brain Res Rev"},{"issue":"2","key":"3_CR86","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2114\/jpa.18.37","volume":"18","author":"K Shinohara","year":"1999","unstructured":"Shinohara K, Yanagisawa A, Kagota Y, Gomi A, Nemoto K, Moriya E, Furusawa E, Furuya K, Terasawa K (1999) Physiological changes in Pachinko players; beta-endorphin, catecholamines, immune system substances and heart rate. Appl Hum Sci 18(2):37\u201342","journal-title":"Appl Hum Sci"},{"issue":"8","key":"3_CR87","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1038\/npp.2009.28","volume":"34","author":"D Simmons","year":"2009","unstructured":"Simmons D, Self DW (2009) Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. Neuropsychopharmacology 34(8):1946\u20131957","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"3_CR88","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00213-006-0640-8","volume":"190","author":"R Sinha","year":"2007","unstructured":"Sinha R, Kimmerling A, Doebrick C, Kosten TR (2007) Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology (Berl) 190(4):569\u2013574","journal-title":"Psychopharmacology (Berl)"},{"issue":"2","key":"3_CR89","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1369-1600.2008.00138.x","volume":"14","author":"M Sofuoglu","year":"2009","unstructured":"Sofuoglu M, Sewell RA (2009) Norepinephrine and stimulant addiction. Addict Biol 14(2):119\u2013129","journal-title":"Addict Biol"},{"issue":"6","key":"3_CR90","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1073\/pnas.89.6.2046","volume":"89","author":"R Spanagel","year":"1992","unstructured":"Spanagel R, Herz A, Shippenberg TS (1992) Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci U S A 89(6):2046\u20132050","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"18","key":"3_CR91","doi-asserted-by":"crossref","first-page":"4512","DOI":"10.1523\/JNEUROSCI.0685-05.2005","volume":"25","author":"XC Tang","year":"2005","unstructured":"Tang XC, McFarland K, Cagle S, Kalivas PW (2005) Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci 25(18):4512\u20134520","journal-title":"J Neurosci"},{"issue":"1","key":"3_CR92","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.drugalcdep.2004.09.004","volume":"78","author":"M Torrens","year":"2005","unstructured":"Torrens M, Fonseca F, Mateu G, Farre M (2005) Efficacy of antidepressants in substance use disorders with and without comorbid depression. A systematic review and meta-analysis. Drug Alcohol Depend 78(1):1\u201322","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"3_CR93","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1369-1600.2010.00208.x","volume":"16","author":"AM Tremblay","year":"2011","unstructured":"Tremblay AM, Desmond RC, Poulos CX, Zack M (2011) Haloperidol modifies instrumental aspects of slot machine gambling in pathological gamblers and healthy controls. Addict Biol 16(3):467\u2013484","journal-title":"Addict Biol"},{"issue":"8","key":"3_CR94","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.biopsych.2010.06.005","volume":"68","author":"NB Urban","year":"2010","unstructured":"Urban NB, Kegeles LS, Slifstein M, Xu X, Martinez D, Sakr E, Castillo F, Moadel T, O'Malley SS, Krystal JH, Abi-Dargham A (2010) Sex differences in striatal dopamine release in young adults after oral alcohol challenge: a positron emission tomography imaging study with [(1)(1)C]raclopride. Biol Psychiatry 68(8):689\u2013696","journal-title":"Biol Psychiatry"},{"issue":"4","key":"3_CR95","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1093\/cercor\/bhp145","volume":"20","author":"H Wageningen van","year":"2010","unstructured":"van Wageningen H, Jorgensen HA, Specht K, Hugdahl K (2010) A 1H-MR spectroscopy study of changes in glutamate and glutamine (Glx) concentrations in frontal spectra after administration of memantine. Cereb Cortex 20(4):798\u2013803","journal-title":"Cereb Cortex"},{"issue":"1","key":"3_CR96","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/oxfordjournals.alcalc.a008238","volume":"32","author":"PP Vescovi","year":"1997","unstructured":"Vescovi PP, Coiro V (1997) Persistence of defective serotonergic and GABAergic controls of growth hormone secretion in long-term abstinent alcoholics. Alcohol Alcohol 32(1):85\u201390","journal-title":"Alcohol Alcohol"},{"issue":"6","key":"3_CR97","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1176\/ajp.147.6.719","volume":"147","author":"ND Volkow","year":"1990","unstructured":"Volkow ND, Fowler JS, Wolf AP, Schlyer D, Shiue CY, Alpert R, Dewey SL, Logan J, Bendriem B, Christman D et al (1990) Effects of chronic cocaine abuse on postsynaptic dopamine receptors. Am J Psychiatry 147(6):719\u2013724","journal-title":"Am J Psychiatry"},{"issue":"2","key":"3_CR98","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/syn.890140210","volume":"14","author":"ND Volkow","year":"1993","unstructured":"Volkow ND, Fowler JS, Wang GJ, Hitzemann R, Logan J, Schlyer DJ, Dewey SL, Wolf AP (1993) Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 14(2):169\u2013177","journal-title":"Synapse"},{"issue":"9","key":"3_CR99","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1111\/j.1530-0277.1996.tb05936.x","volume":"20","author":"ND Volkow","year":"1996","unstructured":"Volkow ND, Wang GJ, Fowler JS, Logan J, Hitzemann R, Ding YS, Pappas N, Shea C, Piscani K (1996) Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcohol Clin Exp Res 20(9):1594\u20131598","journal-title":"Alcohol Clin Exp Res"},{"issue":"6627","key":"3_CR100","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/386830a0","volume":"386","author":"ND Volkow","year":"1997","unstructured":"Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, Hitzemann R, Chen AD, Dewey SL, Pappas N (1997) Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 386(6627):830\u2013833","journal-title":"Nature"},{"issue":"12","key":"3_CR101","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1176\/appi.ajp.158.12.2015","volume":"158","author":"ND Volkow","year":"2001","unstructured":"Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, Sedler M, Logan J, Franceschi D, Gatley J, Hitzemann R, Gifford A, Wong C, Pappas N (2001) Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex. Am J Psychiatry 158(12):2015\u20132021","journal-title":"Am J Psychiatry"},{"issue":"15","key":"3_CR102","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.1523\/JNEUROSCI.0433-05.2005","volume":"25","author":"ND Volkow","year":"2005","unstructured":"Volkow ND, Wang GJ, Ma Y, Fowler JS, Wong C, Ding YS, Hitzemann R, Swanson JM, Kalivas P (2005) Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction. J Neurosci 25(15):3932\u20133939","journal-title":"J Neurosci"},{"issue":"9","key":"3_CR103","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1001\/archpsyc.63.9.999","volume":"63","author":"ND Volkow","year":"2006","unstructured":"Volkow ND, Wang GJ, Begleiter H, Porjesz B, Fowler JS, Telang F, Wong C, Ma Y, Logan J, Goldstein R, Alexoff D, Thanos PK (2006) High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors. Arch Gen Psychiatry 63(9):999\u20131008","journal-title":"Arch Gen Psychiatry"},{"issue":"46","key":"3_CR104","doi-asserted-by":"crossref","first-page":"12700","DOI":"10.1523\/JNEUROSCI.3371-07.2007","volume":"27","author":"ND Volkow","year":"2007","unstructured":"Volkow ND, Wang GJ, Telang F, Fowler JS, Logan J, Jayne M, Ma Y, Pradhan K, Wong C (2007) Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement. J Neurosci 27(46):12700\u201312706","journal-title":"J Neurosci"},{"issue":"37","key":"3_CR105","doi-asserted-by":"crossref","first-page":"15037","DOI":"10.1073\/pnas.1010654108","volume":"108","author":"ND Volkow","year":"2011","unstructured":"Volkow ND, Wang GJ, Fowler JS, Tomasi D, Telang F (2011) Addiction: beyond dopamine reward circuitry. Proc Natl Acad Sci U S A 108(37):15037\u201315042","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"9","key":"3_CR106","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1038\/mp.2011.86","volume":"17","author":"GJ Wang","year":"2012","unstructured":"Wang GJ, Smith L, Volkow ND, Telang F, Logan J, Tomasi D, Wong CT, Hoffman W, Jayne M, Alia-Klein N, Thanos P, Fowler JS (2012) Decreased dopamine activity predicts relapse in methamphetamine abusers. Mol Psychiatry 17(9):918\u2013925","journal-title":"Mol Psychiatry"},{"issue":"7","key":"3_CR107","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1038\/sj.npp.1301263","volume":"32","author":"D Weinshenker","year":"2007","unstructured":"Weinshenker D, Schroeder JP (2007) There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology 32(7):1433\u20131451","journal-title":"Neuropsychopharmacology"},{"issue":"11","key":"3_CR108","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nrn3131","volume":"12","author":"L Welberg","year":"2011","unstructured":"Welberg L (2011) Addiction: from mechanisms to treatment. Nat Rev Neurosci 12(11):621","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"3_CR109","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/sj.npp.1300333","volume":"29","author":"M Zack","year":"2004","unstructured":"Zack M, Poulos CX (2004) Amphetamine primes motivation to gamble and gambling-related semantic networks in problem gamblers. Neuropsychopharmacology 29(1):195\u2013207","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"3_CR110","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.biopsych.2007.06.008","volume":"63","author":"W Zhou","year":"2008","unstructured":"Zhou W, Kalivas PW (2008) N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking. Biol Psychiatry 63(3):338\u2013340","journal-title":"Biol Psychiatry"}],"container-title":["Advances in Experimental Medicine and Biology","Substance and Non-substance Addiction"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-981-10-5562-1_3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T20:51:58Z","timestamp":1750971118000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-981-10-5562-1_3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"ISBN":["9789811055614","9789811055621"],"references-count":110,"URL":"https:\/\/doi.org\/10.1007\/978-981-10-5562-1_3","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}