{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:44:06Z","timestamp":1788374646552,"version":"build-2803163510"},"publisher-location":"Singapore","reference-count":85,"publisher":"Springer Singapore","isbn-type":[{"value":"9789811075711","type":"print"},{"value":"9789811075728","type":"electronic"}],"license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"DOI":"10.1007\/978-981-10-7572-8_5","type":"book-chapter","created":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T09:17:12Z","timestamp":1526894232000},"page":"51-61","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Potential Treatment Options in a Post-antibiotic Era"],"prefix":"10.1007","author":[{"given":"R R","family":"Bragg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Meyburgh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-Y","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Coetzee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,22]]},"reference":[{"key":"5_CR1","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1111\/j.1476-5381.2011.01250.x","volume":"163","author":"A Coates","year":"2011","unstructured":"Coates A, Halls G, Hu Y (2011) Novel classes of antibiotics or more of the same? Br J Pharmacol 163:184\u2013194","journal-title":"Br J Pharmacol"},{"key":"5_CR2","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1155\/2006\/707296","volume":"17","author":"J Davies","year":"2006","unstructured":"Davies J (2006) Where have all the antibiotics gone? Can J Infect Dis Med Microbiol 17:287\u2013290","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"5_CR3","unstructured":"Natural Resources Defense Council (2016) New antibiotics scorecard: number of top restaurant chains restricting use in chicken doubled in 2016 [Internet]. https:\/\/www.nrdc.org\/media\/2016\/160920 . Accessed 27 July 2017"},{"key":"5_CR4","unstructured":"European Centre for Disease Control and Prevention (2009) The bacterial challenge: time to react [Internet]. Reproduction. 2009. http:\/\/ecdc.europa.eu\/en\/publications\/Publications\/0909_TER_The_Bacterial_Challenge_Time_to_React.pdf"},{"key":"5_CR5","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1086\/420937","volume":"38","author":"B Spellberg","year":"2004","unstructured":"Spellberg B, Powers JH, Brass EP, Miller LG, Edwards JE (2004) Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 38:1279\u20131286","journal-title":"Clin Infect Dis"},{"key":"5_CR6","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1002\/anie.200200528","volume":"42","author":"MR Barbachyn","year":"2003","unstructured":"Barbachyn MR, Ford CW (2003) Oxazolidinone structure-activity relationships leading to linezolid. Angew Chemie Int Ed 42:2010\u20132023","journal-title":"Angew Chemie Int Ed"},{"key":"5_CR7","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1111\/j.1368-5031.2005.00885.x","volume":"60","author":"WV Kern","year":"2006","unstructured":"Kern WV (2006) Daptomycin: first in a new class of antibiotics for complicated skin and soft-tissue infections. Int J Clin Pract 60:370\u2013378","journal-title":"Int J Clin Pract"},{"key":"5_CR8","doi-asserted-by":"publisher","first-page":"3664","DOI":"10.1021\/ja500053x","volume":"136","author":"PI O\u2019Daniel","year":"2014","unstructured":"O\u2019Daniel PI, Peng Z, Pi H, Testero SA, Ding D, Spink E et al (2014) Discovery of a new class of non-B-lactam inhibitors of penicillin-binding proteins with gram-positive antibacterial activity. J Am Chem Soc 136:3664\u20133672","journal-title":"J Am Chem Soc"},{"key":"5_CR9","first-page":"25","volume":"66","author":"W Boyle","year":"1955","unstructured":"Boyle W (1955) Spices and essential oils as preservatives. Am Perfum Essent Oil Rev 66:25\u201328","journal-title":"Am Perfum Essent Oil Rev"},{"key":"5_CR10","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/s11101-010-9170-4","volume":"10","author":"MB Isman","year":"2011","unstructured":"Isman MB, Miresmailli S, Machial C (2011) Commercial opportunities for pesticides based on plant essential oils in agriculture, industry and consumer products. Phytochem Rev 10:197\u2013204","journal-title":"Phytochem Rev"},{"key":"5_CR11","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1002\/fsn3.116","volume":"2","author":"H Mith","year":"2014","unstructured":"Mith H, Dur\u00e9 R, Delcenserie V, Zhiri A, Daube G, Clinquart A (2014) Antimicrobial activities of commercial essential oils and their components against food-borne pathogens and food spoilage bacteria. Food Sci Nutr 2:403\u2013416","journal-title":"Food Sci Nutr"},{"key":"5_CR12","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1016\/j.fct.2009.08.005","volume":"47","author":"M Bouaziz","year":"2009","unstructured":"Bouaziz M, Yangui T, Sayadi S, Dhouib A (2009) Disinfectant properties of essential oils from Salvia officinalis L. cultivated in Tunisia. Food Chem Toxicol 47:2755\u20132760","journal-title":"Food Chem Toxicol"},{"key":"5_CR13","first-page":"32","volume":"6","author":"P Ziosi","year":"2010","unstructured":"Ziosi P, Manfredini S, Vertuani S, Ruscetta V, Radice M, Sacchetti G et al (2010) Evaluating essential oils in cosmetics: antioxidant capacity and functionality. Cosmet Toilet 6:32\u201340","journal-title":"Cosmet Toilet"},{"key":"5_CR14","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1254\/jjp.44.77","volume":"44","author":"A Manabe","year":"1987","unstructured":"Manabe A, Nakayama S, Sakamoto K (1987) Effects of essential oils on erythrocytes and hepatocytes from rats and dipalmitoyl phosphatidylcholine-liposomes. Jpn J Pharmacol 44:77\u201384","journal-title":"Jpn J Pharmacol"},{"key":"5_CR15","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1017\/S1751731107000742","volume":"1","author":"J-P Jouany","year":"2007","unstructured":"Jouany J-P, Morgavi DP (2007) Use of \u201cnatural\u201d products as alternatives to antibiotic feed additives in ruminant production. Anim Int J Anim Biosci 1:1443\u20131466","journal-title":"Anim Int J Anim Biosci"},{"key":"5_CR16","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.5713\/ajas.2012.12292","volume":"25","author":"P Li","year":"2012","unstructured":"Li P, Piao X, Ru Y, Han X, Xue L, Zhang H (2012) Effects of adding essential oil to the diet of weaned pigs on performance, nutrient utilization, immune response and intestinal health. Asian-Australasian J Anim Sci 25:1617\u20131626","journal-title":"Asian-Australasian J Anim Sci"},{"key":"5_CR17","doi-asserted-by":"crossref","unstructured":"Bento MHL, Ouwehand AC, Tiihonen K, Lahtinen S, Nurminen P, Saarinen MT et al (2013) Essential oils and their use in animal feeds for monogastric animals-effects on feed quality, gut microbiota, growth performance and food safety: a review. Vet Med (Praha) 58:449\u201358","DOI":"10.17221\/7029-VETMED"},{"key":"5_CR18","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1111\/jam.12334","volume":"115","author":"EK Barbour","year":"2013","unstructured":"Barbour EK, Shaib H, Azhar E, Kumosani T, Iyer A, Harakeh S et al (2013) Modulation by essential oil of vaccine response and production improvement in chicken challenged with velogenic newcastle disease virus. J Appl Microbiol 115:1278\u20131286","journal-title":"J Appl Microbiol"},{"key":"5_CR19","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1111\/jam.12731","volume":"118","author":"EK Barbour","year":"2015","unstructured":"Barbour EK, Bragg RR, Karrouf G, Iyer A, Azhar E, Harakeh S et al (2015) Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil. J Appl Microbiol 118:583\u2013591","journal-title":"J Appl Microbiol"},{"key":"5_CR20","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.mib.2012.08.002","volume":"15","author":"RPN Mishra","year":"2012","unstructured":"Mishra RPN, Oviedo-Orta E, Prachi P, Rappuoli R, Bagnoli F (2012) Vaccines and antibiotic resistance. Curr Opin Microbiol 15:596\u2013602","journal-title":"Curr Opin Microbiol"},{"key":"5_CR21","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1086\/591967","volume":"47","author":"C Azzari","year":"2008","unstructured":"Azzari C, Resti M (2008) Reduction of carriage and transmission of Streptococcus pneumoniae: The beneficial \u201cside effect\u201d of pneumococcal conjugate vaccine. Clin Infect Dis 47:997\u2013999","journal-title":"Clin Infect Dis"},{"key":"5_CR22","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1586\/14760584.7.10.1493","volume":"7","author":"G Gon\u00e7alves","year":"2008","unstructured":"Gon\u00e7alves G (2008) Herd immunity: recent uses in vaccine assessment. Expert Rev Vaccines 7:1493\u20131506","journal-title":"Expert Rev Vaccines"},{"key":"5_CR23","doi-asserted-by":"publisher","first-page":"3245","DOI":"10.1016\/j.vaccine.2009.01.072","volume":"27","author":"D Serruto","year":"2009","unstructured":"Serruto D, Serino L, Masignani V, Pizza M (2009) Genome-based approaches to develop vaccines against bacterial pathogens. Vaccine 27:3245\u20133250","journal-title":"Vaccine"},{"key":"5_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2014.00012","volume":"5","author":"O Finco","year":"2014","unstructured":"Finco O, Rappuoli R (2014) Designing vaccines for the twenty-first century society. Front Immunol 5:1\u20136","journal-title":"Front Immunol"},{"key":"5_CR25","doi-asserted-by":"publisher","first-page":"2688","DOI":"10.1016\/S0264-410X(00)00554-5","volume":"19","author":"R Rappuoli","year":"2001","unstructured":"Rappuoli R (2001) Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 19:2688\u20132691","journal-title":"Vaccine"},{"key":"5_CR26","doi-asserted-by":"publisher","first-page":"1816","DOI":"10.1126\/science.287.5459.1816","volume":"287","author":"M Pizza","year":"2000","unstructured":"Pizza M, Scarlato V, Masignani V, Giuliani MM, Arico B, Comanducci M et al (2000) Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287:1816\u20131820","journal-title":"Science"},{"key":"5_CR27","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1128\/CMR.7.4.559","volume":"7","author":"JD Romero","year":"1994","unstructured":"Romero JD, Outschoorn IM (1994) Current status of meningococcal Group B vaccine candidates: capsular or noncapsular? Clin Microbiol Rev 7:559\u2013575","journal-title":"Clin Microbiol Rev"},{"key":"5_CR28","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1126\/science.287.5459.1809","volume":"247","author":"H Tettelin","year":"2000","unstructured":"Tettelin H, Saunders NJ, Heidelberg J, Jeffries AC, Nelson KE, Eisen JA et al (2000) Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 247:1809\u20131815","journal-title":"Science"},{"key":"5_CR29","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.immuni.2010.09.017","volume":"33","author":"A Sette","year":"2012","unstructured":"Sette A, Rappuoli R (2012) Reverse vaccinology: developing vaccines in the era of genomics. Immunity 33:530\u2013541","journal-title":"Immunity"},{"key":"5_CR30","doi-asserted-by":"publisher","first-page":"1315","DOI":"10.1126\/science.4001944","volume":"228","author":"GP Smith","year":"1985","unstructured":"Smith GP (1985) Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228:1315\u20131317","journal-title":"Science"},{"key":"5_CR31","doi-asserted-by":"crossref","first-page":"4318","DOI":"10.1016\/S0021-9258(18)68927-6","volume":"263","author":"VF Cruz De La","year":"1988","unstructured":"De La Cruz VF, Lal AA, McCutchan TF (1988) Immunogenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage. J Biol Chem 263:4318\u20134322","journal-title":"J Biol Chem"},{"key":"5_CR32","doi-asserted-by":"publisher","first-page":"4188","DOI":"10.1016\/j.vaccine.2006.01.001","volume":"24","author":"NE Houten Van","year":"2006","unstructured":"Van Houten NE, Zwick MB, Menendez A, Scott JK (2006) Filamentous phage as an immunogenic carrier to elicit focused antibody responses against a synthetic peptide. Vaccine 24:4188\u20134200","journal-title":"Vaccine"},{"key":"5_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12929-016-0285-9","volume":"23","author":"L Aghebati-Maleki","year":"2016","unstructured":"Aghebati-Maleki L, Bakhshinejad B, Baradaran B, Motallebnezhad M, Aghebati-Maleki A, Nickho H et al (2016) Phage display as a promising approach for vaccine development. J Biomed Sci 23:1\u201318","journal-title":"J Biomed Sci"},{"key":"5_CR34","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.vetmic.2006.08.034","volume":"119","author":"H Wang","year":"2007","unstructured":"Wang H, Gao Y, Gong Y, Chen X, Liu C, Zhou X et al (2007) Identification and immunogenicity of an immunodominant mimotope of Avibacterium paragallinarum from a phage display peptide library. Vet Microbiol 119:231\u2013239","journal-title":"Vet Microbiol"},{"key":"5_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/382539","volume":"2014","author":"M Elbreki","year":"2014","unstructured":"Elbreki M, Ross RP, Hill C, O\u2019Mahony J, McAuliffe O, Coffey A (2014) Bacteriophages and their derivatives as biotherapeutic agents in disease prevention and treatment. J Viruses 2014:1\u201320","journal-title":"J Viruses"},{"key":"5_CR36","doi-asserted-by":"crossref","unstructured":"Bragg R, Boucher C, van der Westhuizen W, Lee J-Y, Coetsee E, Theron C et al (2016) Bacteriophage therapy as a treatment option in a post-antibiotic era. In: Kon KV, Rai M (ed) Antibiotics resistant: mechanisms and new antimicrobial approaches, 1st ed. Elsevier, Amsterdam, pp 309\u201328","DOI":"10.1016\/B978-0-12-803642-6.00015-0"},{"key":"5_CR37","unstructured":"Slopek S, Weber-Dabrowska B, Dabrowski M, Kucharewicz-Krukowska A (1987) Results of bacteriophage treatment of suppurative bacterial infections in the years 1981\u20131986. Arch Immunol Ther Exp (Warsz) 35:569\u201383"},{"key":"5_CR38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4103\/2231-4040.70513","volume":"1","author":"S Bhattacharya","year":"2010","unstructured":"Bhattacharya S (2010) The facts about penicillin allergy: a review. J Adv Pharm Technol Res 1:11\u201317","journal-title":"J Adv Pharm Technol Res"},{"key":"5_CR39","doi-asserted-by":"crossref","unstructured":"\u00d6rm\u00e4l\u00e4 A, Jalasvuori M (2013) Should bacterial resistance to phages be a concern, even in the long run? Bacteriophage:3","DOI":"10.4161\/bact.24219"},{"key":"5_CR40","doi-asserted-by":"publisher","first-page":"50","DOI":"10.4161\/bact.18609","volume":"2","author":"ST Abedon","year":"2012","unstructured":"Abedon ST (2012) Bacterial \u201cimmunity\u201d against bacteriophages. Bacteriophage 2:50\u201354","journal-title":"Bacteriophage"},{"key":"5_CR41","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/nrmicro2315","volume":"8","author":"SJ Labrie","year":"2010","unstructured":"Labrie SJ, Samson JE, Moineau S (2010) Bacteriophage resistance mechanisms. Nat Rev Microbiol 8:317\u2013327","journal-title":"Nat Rev Microbiol"},{"key":"5_CR42","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1126\/science.1138140","volume":"315","author":"R Barrangou","year":"2007","unstructured":"Barrangou R, Fremaux C, Devaux H, Richards M, Boyaval P, Moineau S et al (2007) CRISPR provides acquired resistance against viruses in prokaryotes. Science 315:1709\u20131712","journal-title":"Science"},{"key":"5_CR43","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.biochi.2015.03.025","volume":"117","author":"D Rath","year":"2015","unstructured":"Rath D, Amlinger L, Rath A, Lundgren M (2015) The CRISPR-Cas immune system: biology, mechanisms and applications. Biochimie 117:119\u2013128","journal-title":"Biochimie"},{"issue":"1494","key":"5_CR44","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1098\/rspb.2001.1945","volume":"269","author":"A. Buckling","year":"2002","unstructured":"Buckling A, Rainey PB (2002) Antagonistic coevolution between a bacterium and a bacteriophage. Proc R Soc London B:931\u20136","journal-title":"Proceedings of the Royal Society B: Biological Sciences"},{"key":"5_CR45","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1038\/nature11723","volume":"493","author":"J Bondy-Denomy","year":"2016","unstructured":"Bondy-Denomy J, Pawluk A, Maxwell KL, Davidson AR (2016) Bacteriophage genes that inactivate the CRISPR\/Cas bacterial immune system. Nature 493:429\u2013432","journal-title":"Nature"},{"key":"5_CR46","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1038\/nature11927","volume":"494","author":"KD Seed","year":"2013","unstructured":"Seed KD, Lazinski DW, Calderwood SB, Camilli A (2013) A bacteriophage encodes its own CRISPR\/Cas adaptive response to evade host innate immunity. Nature 494:489\u2013491","journal-title":"Nature"},{"key":"5_CR47","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.tim.2005.08.007","volume":"13","author":"VA Fischetti","year":"2005","unstructured":"Fischetti VA (2005) Bacteriophage lytic enzymes: novel anti-infectives. Trends Microbiol 13:491\u2013496","journal-title":"Trends Microbiol"},{"key":"5_CR48","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1146\/annurev.micro.54.1.799","volume":"54","author":"I-N Wang","year":"2000","unstructured":"Wang I-N, Smith DL, Young R (2000) Holins: The protein clocks of bacteriophage infections. Annu Rev Microbiol 54:799\u2013825","journal-title":"Annu Rev Microbiol"},{"key":"5_CR49","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1111\/1574-6976.12006","volume":"37","author":"MJ Catal\u00e3o","year":"2013","unstructured":"Catal\u00e3o MJ, Gil F, Moniz-Pereira J, S\u00e3o-Jos\u00e9 C, Pimentel M (2013) Diversity in bacterial lysis systems: bacteriophages how the way. FEMS Microbiol Rev 37:554\u2013571","journal-title":"FEMS Microbiol Rev"},{"key":"5_CR50","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/1574-6968.12338","volume":"350","author":"L Ti\u0161\u00e1kov\u00e1","year":"2014","unstructured":"Ti\u0161\u00e1kov\u00e1 L, Vidov\u00e1 B, Farka\u0161ovsk\u00e1 J, God\u00e1ny A (2014) Bacteriophage endolysin Lyt \u03bc1\/6: characterization of the C-terminal binding domain. FEMS Microbiol Lett 350:199\u2013208","journal-title":"FEMS Microbiol Lett"},{"key":"5_CR51","doi-asserted-by":"publisher","first-page":"4107","DOI":"10.1073\/pnas.061038398","volume":"98","author":"D Nelson","year":"2001","unstructured":"Nelson D, Loomis L, Fischetti VA (2001) Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme. Proc Natl Acad Sci 98:4107\u20134112","journal-title":"Proc Natl Acad Sci"},{"key":"5_CR52","doi-asserted-by":"publisher","first-page":"2170","DOI":"10.1126\/science.1066869","volume":"294","author":"JM Loeffler","year":"2001","unstructured":"Loeffler JM, Nelson D, Fischetti VA (2001) Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase. Science 294:2170\u20132172","journal-title":"Science"},{"key":"5_CR53","first-page":"1","volume":"6","author":"H Dong","year":"2015","unstructured":"Dong H, Zhu C, Chen J, Ye X, Huang YP (2015) Antibacterial activity of Stenotrophomonas maltophilia endolysin P28 against both gram-positive and gram-negative bacteria. Front Microbiol 6:1\u20138","journal-title":"Front Microbiol"},{"key":"5_CR54","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1089\/mdr.2012.0025","volume":"18","author":"S Fernandes","year":"2012","unstructured":"Fernandes S, Proen\u00e7a D, Cantante C, Silva FA, Leandro C, Louren\u00e7o S et al (2012) Novel chimerical endolysins with broad antimicrobial activity against methicillin-resistant Staphylococcus aureus. Microb Drug Resist 18:333\u2013343","journal-title":"Microb Drug Resist"},{"issue":"27","key":"5_CR55","doi-asserted-by":"publisher","first-page":"11197","DOI":"10.1073\/pnas.0704624104","volume":"104","author":"TK Lu","year":"2007","unstructured":"Lu TK, Collins JJ (2007) Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci 104(27):11197\u2013202","journal-title":"Proc Natl Acad Sci"},{"key":"5_CR56","first-page":"1","volume":"71","author":"RR Bragg","year":"2004","unstructured":"Bragg RR (2004) Limitation of the spread and impact of infectious coryza through the use of a continuous disinfection programme. Onderstepoort J Vet Res 71:1\u20138","journal-title":"Onderstepoort J Vet Res"},{"key":"5_CR57","first-page":"219","volume":"70","author":"RR Bragg","year":"2003","unstructured":"Bragg RR, Plumstead P (2003) Continuous disinfection as a means to control infectious diseases in poultry: evaluation of a continuous disinfection programme for broilers. Onderstepoort J Vet Res 70:219\u2013229","journal-title":"Onderstepoort J Vet Res"},{"key":"5_CR58","doi-asserted-by":"publisher","first-page":"S57","DOI":"10.1016\/S0195-6701(99)90066-X","volume":"43","author":"A.D. Russell","year":"1999","unstructured":"Russell AD (1998) Bacterial resistance to disinfectants: present knowledge and future problems. J Hosp Infect 43 (Supple):S57\u201368","journal-title":"Journal of Hospital Infection"},{"key":"5_CR59","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1089\/mdr.2009.0120","volume":"16","author":"K Hegstad","year":"2010","unstructured":"Hegstad K, Langsrud S, Lunestad BT, Scheie AA, Sunde M, Yazdankhah SP (2010) Does the wide use of quaternary ammonium compounds enhance the selection and spread of antimicrobial resistance and thus threaten our health? Microb Drug Resist 16:91\u2013104","journal-title":"Microb Drug Resist"},{"issue":"2","key":"5_CR60","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1046\/j.1365-2672.1997.00198.x","volume":"83","author":"AD Russell","year":"1997","unstructured":"Russell AD (1997) Plasmids and bacterial resistance to biocides. J Appl Microbiol 83(2):155\u201365","journal-title":"J Appl Microbiol"},{"key":"5_CR61","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1128\/CMR.12.1.147","volume":"12","author":"G McDonnell","year":"1999","unstructured":"McDonnell G, Russell AD (1999) Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 12:147\u2013179","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"5_CR62","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1046\/j.1365-2672.1999.00770.x","volume":"86","author":"L M\u00e9chin","year":"1999","unstructured":"M\u00e9chin L, Dubois-Brissonnet F, Heyd B, Leveau JY (1999) Adaptation of Pseudomonas aeruginosa ATCC 15442 to didecyldimethylammonium bromide induces changes in membrane fatty acid composition and in resistance of cells. J Appl Microbiol 86(5):859\u201366","journal-title":"J Appl Microbiol"},{"key":"5_CR63","doi-asserted-by":"publisher","first-page":"E151","DOI":"10.3168\/jds.S0022-0302(01)70209-3","volume":"84","author":"DG White","year":"2001","unstructured":"White DG, McDermott PF (2001) Emergence and transfer of antibacterial resistance. J Dairy Sci 84:E151\u2013E155","journal-title":"J Dairy Sci"},{"key":"5_CR64","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0378-1097(97)00379-0","volume":"156","author":"IT Paulsen","year":"1997","unstructured":"Paulsen IT, Park JH, Choi PS, Saier MH Jr (1997) A family of Gram-negative bacterial outer membrane factors that function in the export of protiens, carbohydrates, drugs and heavy metals from Gram-negative bacteria. FEMS Microbiol Lett 156:1\u20138","journal-title":"FEMS Microbiol Lett"},{"key":"5_CR65","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1128\/AEM.21.6.1058-1063.1971","volume":"21","author":"FW Adair","year":"1971","unstructured":"Adair FW, Geftic S, Gelzer J (1971) Resistance of Pseudomonas to quaternary ammonium compounds. Appl Microbiol 21:1058\u20131063","journal-title":"Appl Microbiol"},{"key":"5_CR66","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1128\/AAC.34.10.1865","volume":"34","author":"P Gilbert","year":"1990","unstructured":"Gilbert P, Collier PJ, Brown MR (1990) Influence of growth rate on susceptibility to antimicrobial agents: biofilms, cell cycle, dormancy, and stringent response. Antimicrob Agents Chemother 34:1865\u20131868","journal-title":"Antimicrob Agents Chemother"},{"key":"5_CR67","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1128\/AAC.46.5.1469-1474.2002","volume":"46","author":"C Campanac","year":"2002","unstructured":"Campanac C, Pineau L, Payard A, Baziard-Mouysset G, Roques C (2002) Interactions between biocide cationic agents and bacterial biofilms. Antimicrob Agents Chemother 46:1469\u20131474","journal-title":"Antimicrob Agents Chemother"},{"key":"5_CR68","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.ijantimicag.2012.01.011","volume":"39","author":"S Buffet-Bataillon","year":"2012","unstructured":"Buffet-Bataillon S, Tattevin P, Bonnaure-Mallet M, Jolivet-Gougeon A (2012) Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds\u2014a critical review. Int J Antimicrob Agents 39:381\u2013389","journal-title":"Int J Antimicrob Agents"},{"key":"5_CR69","doi-asserted-by":"publisher","first-page":"3449","DOI":"10.1128\/AEM.70.6.3449-3456.2004","volume":"70","author":"AJ McBain","year":"2004","unstructured":"McBain AJ, Ledder RG, Moore LE, Carl E, Gilbert P, Catrenich CE (2004) Effects of quaternary-ammonium-based formulations on bacterial community dynamics and antimicrobial susceptibility. Appl Environ Microbiol 70:3449\u20133456","journal-title":"Appl Environ Microbiol"},{"issue":"11","key":"5_CR70","doi-asserted-by":"publisher","first-page":"3999","DOI":"10.1128\/JCM.39.11.3999-4004.2001","volume":"39","author":"J. Bjorland","year":"2001","unstructured":"Bjorland J, Sunde M, Waage S (2001) Plasmid-borne smr gene causes resistance to quaternary ammonium compounds in bovine Staphylococcus aureus. J Clin Microbiol 39:3999\u20134004","journal-title":"Journal of Clinical Microbiology"},{"key":"5_CR71","doi-asserted-by":"publisher","first-page":"4363","DOI":"10.1128\/JCM.43.9.4363-4368.2005","volume":"43","author":"J Bjorland","year":"2005","unstructured":"Bjorland J, Steinum T, Kvitle B, Waage S, Sunde M, Heir E (2005) Widespread distribution of disinfectant resistance genes among staphylococci of bovine and caprine origin in Norway. J Clin Microbiol 43:4363\u20134368","journal-title":"J Clin Microbiol"},{"key":"5_CR72","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1128\/AAC.00375-06","volume":"51","author":"CJ Ioannou","year":"2007","unstructured":"Ioannou CJ, Hanlon GW, Denyer SP (2007) Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. Antimicrob Agents Chemother 51:296\u2013306","journal-title":"Antimicrob Agents Chemother"},{"issue":"10","key":"5_CR73","doi-asserted-by":"publisher","first-page":"3046","DOI":"10.1128\/AAC.47.10.3046-3052.2003","volume":"47","author":"J Bjorland","year":"2003","unstructured":"Bjorland J, Steinum T, Sunde M, Waage S, Heir E (2003) Novel plasmid-borne gene qacJ mediates resistance to quaternary ammonium compounds in equine Staphylococcus aureus, Staphylococcus simulans, and Staphylococcus intermedius. Antimicrob Agents Chemother. 47(10):3046\u201352","journal-title":"Antimicrob Agents Chemother."},{"key":"5_CR74","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0168-1605(99)00044-6","volume":"48","author":"E Heir","year":"1999","unstructured":"Heir E, Sundheim G, Holck AL (1999) Identification and characterization of quaternary ammonium compound resistant staphylococci from the food industry. Int J Food Microbiol 48:211\u2013219","journal-title":"Int J Food Microbiol"},{"key":"5_CR75","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1046\/j.1365-2672.1999.00672.x","volume":"86","author":"E Heir","year":"1999","unstructured":"Heir E, Sundheim G, Holck AL (1999) The qacG gene on plasmid pST94 confers resistance to quaternary ammonium compounds in staphylococci isolated from the food industry. J Appl Microbiol 86:378\u2013388","journal-title":"J Appl Microbiol"},{"key":"5_CR76","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1111\/j.1574-6968.1998.tb13025.x","volume":"163","author":"E Heir","year":"1998","unstructured":"Heir E, Sundheim G, Holck AL (1998) The Staphylococcus qacH gene product: a new member of the SMR family encoding multidrug resistance. FEMS Microbiol Lett 163:49\u201356","journal-title":"FEMS Microbiol Lett"},{"key":"5_CR77","doi-asserted-by":"publisher","first-page":"3606","DOI":"10.1128\/AAC.46.11.3606-3612.2002","volume":"46","author":"I Anthonisen","year":"2002","unstructured":"Anthonisen I, Sunde M, Steinum TM, Sidhu MS, S\u00f8rum H (2002) Organization of the antiseptic resistance gene qacA and Tn 552 -related \u03b2 -lactamase genes in multidrug-resistant Staphylococcus haemolyticus strains of animal and human origins. Antimicrob Agents Chemother 46:3606\u20133612","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"5_CR78","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1046\/j.1365-2672.2003.02064.x","volume":"95","author":"S Langsrud","year":"2003","unstructured":"Langsrud S, Sundheim G, Borgmann-Strahsen R (2003) Intrinsic and acquired resistance to quaternary ammonium compounds in food-related Pseudomonas spp. J Appl Microbiol 95(4):874\u201382","journal-title":"J Appl Microbiol"},{"issue":"supplement 1","key":"5_CR79","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/107662903322541838","volume":"9","author":"Mohammed Mahbub Alam","year":"2003","unstructured":"Alam MM, Ishino M, Kobayashi N (2003) Analysis of genomic diversity and evolution of the low-level antiseptic resistance gene smr in Staphylococcus aureus. Microb Drug Resist 9:S-1\u2013S-7","journal-title":"Microbial Drug Resistance"},{"issue":"1","key":"5_CR80","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/0378-1119(91)90224-Y","volume":"101","author":"Tim G. Littlejohn","year":"1991","unstructured":"Littlejohn TG, DiBerardino D, Messerotti LJ, Spiers SJ, Skurray RA (1991) Structure and evolution of a family of genes encoding antiseptic and disinfectant resistance in Staphylococcus aureus. Gene 101:59\u201366","journal-title":"Gene"},{"key":"5_CR81","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1128\/jb.177.10.2827-2833.1995","volume":"177","author":"IT Paulsen","year":"1995","unstructured":"Paulsen IT, Brown MH, Dunstan SJ, Skurray RA (1995) Molecular characterization of the Staphylococcal multidrug resistance export protein QacC. J Bacteriol 177:2827\u20132833","journal-title":"J Bacteriol"},{"key":"5_CR82","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/j.1574-6968.2009.01646.x","volume":"296","author":"MR Gillings","year":"2009","unstructured":"Gillings MR, Holley MP, Stokes HW (2009) Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilms. FEMS Microbiol Lett 296:282\u2013288","journal-title":"FEMS Microbiol Lett"},{"key":"5_CR83","first-page":"209","volume":"3","author":"MR Gillings","year":"2009","unstructured":"Gillings MR, Xuejun D, Hardwick SA, Holley MP, Stokes HW (2009) Gene cassettes encoding resistance to quaternary ammonium compounds: a role in the origin of clinical class 1 integrons? Int Soc Microb Ecol J 3:209\u2013215","journal-title":"Int Soc Microb Ecol J"},{"key":"5_CR84","doi-asserted-by":"publisher","first-page":"3015","DOI":"10.1099\/13500872-141-12-3015","volume":"141","author":"GD Recchia","year":"1995","unstructured":"Recchia GD, Hall RM (1995) Gene cassettes: a new class of mobile element. Microbiology 141:3015\u20133027","journal-title":"Microbiology"},{"key":"5_CR85","first-page":"3014","volume":"45","author":"SR Partridge","year":"2001","unstructured":"Partridge SR, Recchia GD, Stokes HW, Hall M (2001) Family of Class 1 integrons related to In4 from Tn 1696. Society 45:3014\u20133020","journal-title":"Society"}],"container-title":["Advances in Experimental Medicine and Biology","Infectious Diseases and Nanomedicine III"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-981-10-7572-8_5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T22:04:55Z","timestamp":1720303495000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-981-10-7572-8_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"ISBN":["9789811075711","9789811075728"],"references-count":85,"URL":"https:\/\/doi.org\/10.1007\/978-981-10-7572-8_5","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}