{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:28:38Z","timestamp":1771622918687,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[1966,5,1]],"date-time":"1966-05-01T00:00:00Z","timestamp":-115862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1966,5,1]],"date-time":"1966-05-01T00:00:00Z","timestamp":-115862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kybernetik"],"published-print":{"date-parts":[[1966,5]]},"DOI":"10.1007\/bf00299899","type":"journal-article","created":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T17:58:39Z","timestamp":1097258319000},"page":"67-82","source":"Crossref","is-referenced-by-count":61,"title":["Spike probability in neurones: influence of temporal structure in the train of synaptic events"],"prefix":"10.1007","volume":"3","author":[{"given":"Jos\u00e9 P.","family":"Segundo","sequence":"first","affiliation":[]},{"given":"Donald H.","family":"Perkel","sequence":"additional","affiliation":[]},{"given":"George P.","family":"Moore","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF00299899_CR1","first-page":"717","volume-title":"Sensory communication","author":"T. H. Bullock","year":"1961","unstructured":"Bullock, T. H.: The problem of recognition in an analyzer made of neurons. In: Sensory communication, p. 717\u2013724 (Ed. W. A. Rosenblith). New York: M. I. T. Press & John Wiley & Sons 1961."},{"key":"BF00299899_CR2","volume-title":"Structure and function in the nervous systems of invertebrates","author":"T. H. Bullock","year":"1965","unstructured":"Bullock, T. H., and C. A. Horridge: Structure and function in the nervous systems of invertebrates. San Francisco: W. H. Freeman & Co. 1965."},{"key":"BF00299899_CR3","volume-title":"Renewal theory","author":"D. R. Cox","year":"1962","unstructured":"Cox, D. R.: Renewal theory. London: Methuen & Co., Ltd. 1962."},{"key":"BF00299899_CR4","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/BF02269100","volume":"51","author":"J. C. Eccles","year":"1961","unstructured":"Eccles, J. C.: The mechanism of synaptic transmission. Ergebn. Physiol. 51, 299\u2013430 (1961).","journal-title":"Ergebn. Physiol."},{"key":"BF00299899_CR5","volume-title":"Personal communication","author":"C. Eyzaguirre","year":"1964","unstructured":"Eyzaguirre, C.: Personal communication. Dept. of Physiology, University of Utah Medical College, Salt Lake City, Utah 1964."},{"key":"BF00299899_CR6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1113\/jphysiol.1952.sp004735","volume":"117","author":"P. Fatt","year":"1952","unstructured":"Fatt, P., and P. Katz: Spontaneous subthreshold activity at motor nerve endings. J. Physiol. (Lond.) 117, 109\u2013128 (1952).","journal-title":"J. Physiol. (Lond.)"},{"key":"BF00299899_CR7","volume-title":"An introduction to probability theory and its applications, vol. 1","author":"W. Feller","year":"1957","unstructured":"Feller, W.: An introduction to probability theory and its applications, vol. 1, 2nd edit. New York: John Wiley & Sons 1957.","edition":"2nd edit."},{"key":"BF00299899_CR8","doi-asserted-by":"crossref","DOI":"10.1037\/14003-000","volume-title":"Statistics: an introduction","author":"D. A. S. Fraser","year":"1958","unstructured":"Fraser, D. A. S.: Statistics: an introduction. New York: John Wiley & Sons 1958."},{"key":"BF00299899_CR9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0006-3495(60)86872-5","volume":"1","author":"G. L. Gerstein","year":"1960","unstructured":"Gerstein, G. L., and N. Y. -S. Kiang: An approach to the quantitative analysis of electrophysiological data from single neurons. Biophys. J. 1, 15\u201328 (1960).","journal-title":"Biophys. J."},{"key":"BF00299899_CR10","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1038\/199876a0","volume":"199","author":"J. S. Griffith","year":"1963","unstructured":"Griffith, J. S., and G. Horn: Functional coupling between cells in the visual cortex of the unrestrained cat. Nature (Lond.) 199, 892\u2013895 (1963).","journal-title":"Nature (Lond.)"},{"key":"BF00299899_CR11","doi-asserted-by":"crossref","first-page":"234","DOI":"10.2170\/jjphysiol.4.234","volume":"4","author":"S. Hagiwara","year":"1954","unstructured":"Hagiwara, S.: Analysis of interval fluctuations of the sensory nerve impulse. Jap. J. Physiol. 4, 234\u2013240 (1954).","journal-title":"Jap. J. Physiol."},{"key":"BF00299899_CR12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1242\/jeb.39.1.45","volume":"39","author":"G. M. Hughes","year":"1962","unstructured":"Hughes, G. M., and L. Tauc: Aspects of the organization of central nervous pathways in Aplysia depilans. J. Exp. Biol. 39, 45\u201369 (1962).","journal-title":"J. Exp. Biol."},{"key":"BF00299899_CR13","first-page":"271","volume":"55","author":"E. R. Kandel","year":"1963","unstructured":"Kandel, E. R., et L. Tauc: Augmentation prolong\u00e9e de l'efficacit\u00e9 d'une voie aff\u00e9rente d'un ganglion isol\u00e9 apr\u00e8s l'activation coupl\u00e9e d'une voie plus efficace. J. Physiol. (Paris) 55, 271\u2013272 (1963).","journal-title":"J. Physiol. (Paris)"},{"key":"BF00299899_CR14","volume-title":"Mathematical foundations of information theory","author":"A. I. Khinchin","year":"1957","unstructured":"Khinchin, A. I.: Mathematical foundations of information theory. New York: Dover Publ. Inc. 1957."},{"key":"BF00299899_CR15","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1214\/aoms\/1177704984","volume":"32","author":"G. Marsaglia","year":"1961","unstructured":"Marsaglia, G.: Generating exponential random variables. Ann. Math. Stat. 32, 899\u2013900 (1961).","journal-title":"Ann. Math. Stat."},{"key":"BF00299899_CR16","first-page":"184","volume-title":"Proc. of the San Diego Sympos. for Biomed. Engng.","author":"G. P. Moore","year":"1963","unstructured":"Moore, G. P., J. P. Segundo, and D. H. Perkel: Stability patterns in interneuronal pacemaker regulation. In: Proc. of the San Diego Sympos. for Biomed. Engng., p. 184\u2013193 (Ed. A. Paull). La Jolla, Calif.: San Diego Sympos. for Biomed. Engng. 1963."},{"key":"BF00299899_CR17","volume-title":"Modern probability theory and its applications","author":"E. Parzen","year":"1960","unstructured":"Parzen, E.: Modern probability theory and its applications. New York: John Wiley & Sons 1960."},{"key":"BF00299899_CR18","unstructured":"Perkel, D. H.: A digital-computer model of nerve-cell functioning. The RAND Corp. Memorandum RM-4132-NIH. Santa Monica, California 1964a; Detection of functional interactions among neurons: a technique using repetitive presentations of stimuli. The RAND Corp. Memorandum RM-4234-NIH. Santa Monica, California 1964b."},{"key":"BF00299899_CR19","first-page":"347","volume-title":"Biomedical sciences instrumentation, vol. 1","author":"D. H. Perkel","year":"1963","unstructured":"Perkel, D. H., G. P. Moore, and J. P. Segundo: Continuous-time simulation of ganglion nerve cells in Aplysia. In: Biomedical sciences instrumentation, vol. 1, p. 347\u2013357 (Ed. F. Alt). New York: Plenum Press 1963."},{"key":"BF00299899_CR20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1126\/science.145.3627.61","volume":"145","author":"D. H. Perkel","year":"1964","unstructured":"Perkel, D. H., J. H. Schulman, T. H. Bullock, G. P. Moore, and J. P. Segundo: Pacemaker neurons: effects of regularly spaced synaptic input. Science 145, 61\u201363 (1964).","journal-title":"Science"},{"key":"BF00299899_CR21","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1152\/jn.1964.27.4.517","volume":"27","author":"G. F. Poggio","year":"1964","unstructured":"Poggio, G. F., and L. J. Viernstein: Time series analysis of impulse sequences of thalamic somatic sensory neurons. J. Neurophysiol. 27, 517\u2013545 (1964).","journal-title":"J. Neurophysiol."},{"key":"BF00299899_CR22","first-page":"387","volume":"8","author":"N. N. Preobrazhenskii","year":"1963","unstructured":"Preobrazhenskii, N. N., and N. V. Yarovitskii: The application of mathematical methods for investigating the impulse activity of central neurons of the brain. Biofizika 8, 387\u2013393 (1963).","journal-title":"Biofizika"},{"key":"BF00299899_CR23","first-page":"1","volume":"3","author":"S. H. Ripley","year":"1953","unstructured":"Ripley, S. H., and G. A. G. Wiersma: The effect of spaced stimulation of excitatory and inhibitory axons of the crayfish. Physiol. Comp. et Oecol. 3, 1\u201317 (1953).","journal-title":"Physiol. Comp. et Oecol."},{"key":"BF00299899_CR24","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0006-3495(62)86860-X","volume":"2","author":"R. W. Rodieck","year":"1962","unstructured":"Rodieck, R. W., N. Y.-S. Kiang, and G. L. Gerstein: Some quantitative methods for the study of spontaneous activity of single neurons. Biophys. J. 2, 351\u2013368 (1962).","journal-title":"Biophys. J."},{"key":"BF00299899_CR25","first-page":"371","volume":"21","author":"J. P. Segundo","year":"1963","unstructured":"Segundo, J. P., and G. P. Moore: Functional significance of neuronal spike discharge parameters. Bol. Inst. Estud. M\u00e9d. Biol. (M\u00e9x.) 21, 371\u2013373 (1963).","journal-title":"Bol. Inst. Estud. M\u00e9d. Biol. (M\u00e9x.)"},{"key":"BF00299899_CR26","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1242\/jeb.40.4.643","volume":"40","author":"J. P. Segundo","year":"1963","unstructured":"Segundo, J. P., G. P. Moore, L. J. Stensaas, and T. H. Bullook: Sensitivity of neurones in Aplysia to temporal pattern of arriving impulses. J. Exp. Biol. 40, 643\u2013667 (1963).","journal-title":"J. Exp. Biol."},{"key":"BF00299899_CR27","first-page":"157","volume":"69","author":"T. Wakabayashi","year":"1961","unstructured":"Wakabayashi, T.: Studies on adaptively repetitive stimulation: biological pattern of repetitive stimulation. Tokyo J. Med. Sci. 69, 157\u2013179 (1961).","journal-title":"Tokyo J. Med. Sci."},{"key":"BF00299899_CR28","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1152\/jn.1963.26.6.958","volume":"26","author":"G. Werner","year":"1963","unstructured":"Werner, G., and V. B. Mountcastle: The variability of central neural activity in a sensory system and its implications for the central reflection of sensory events. J. Neurophysiol. 26, 958\u2013977 (1963).","journal-title":"J. Neurophysiol."},{"key":"BF00299899_CR29","first-page":"20","volume":"2","author":"C. A. G. Wiersma","year":"1950","unstructured":"Wiersma, C. A. G., and R. T. Adams: The influence of nerve impulse sequence on the contractions of different crustacean muscles. Physiol. Comp. et Oecol. 2, 20\u201323 (1950).","journal-title":"Physiol. Comp. et Oecol."},{"key":"BF00299899_CR30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0006-3495(65)86706-6","volume":"5","author":"D. M. Wilson","year":"1965","unstructured":"Wilson, D. M., and R. J. Wyman: Motor output patterns during random and rhythmic stimulation of locust thoracic ganglia. Biophys. J. 5, 121\u2013143 (1965).","journal-title":"Biophys. J."}],"container-title":["Kybernetik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00299899.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF00299899\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00299899","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF00299899.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,29]],"date-time":"2023-04-29T13:38:51Z","timestamp":1682775531000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF00299899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,5]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1966,5]]}},"alternative-id":["BF00299899"],"URL":"https:\/\/doi.org\/10.1007\/bf00299899","relation":{},"ISSN":["0023-5946"],"issn-type":[{"value":"0023-5946","type":"print"}],"subject":[],"published":{"date-parts":[[1966,5]]}}}