{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:44:30Z","timestamp":1770504270478,"version":"3.49.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cancer Immunol Immunother"],"published-print":{"date-parts":[[1993,1]]},"DOI":"10.1007\/bf01789125","type":"journal-article","created":{"date-parts":[[2005,6,20]],"date-time":"2005-06-20T12:49:49Z","timestamp":1119271789000},"page":"9-17","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":91,"title":["Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: Effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene"],"prefix":"10.1007","volume":"36","author":[{"given":"Lei","family":"Ding","sequence":"first","affiliation":[]},{"given":"El-Nasir","family":"Lalani","sequence":"additional","affiliation":[]},{"given":"Mark","family":"Reddish","sequence":"additional","affiliation":[]},{"given":"Rao","family":"Koganty","sequence":"additional","affiliation":[]},{"given":"Ting","family":"Wong","sequence":"additional","affiliation":[]},{"given":"John","family":"Samuel","sequence":"additional","affiliation":[]},{"given":"Mary Beth","family":"Yacyshyn","sequence":"additional","affiliation":[]},{"given":"Alison","family":"Meikle","sequence":"additional","affiliation":[]},{"given":"Peter Y. S.","family":"Fung","sequence":"additional","affiliation":[]},{"given":"Joyce","family":"Taylor-Papadimitriou","sequence":"additional","affiliation":[]},{"given":"B. Michael","family":"Longenecker","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"BF01789125_CR1","doi-asserted-by":"crossref","first-page":"7159","DOI":"10.1073\/pnas.86.18.7159","volume":"86","author":"DL Barnd","year":"1989","unstructured":"Barnd DL, Lan MS, Metzgar RS, Finn OJ (1989) Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells. Proc Natl Acad Sci USA 86: 7159","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF01789125_CR2","first-page":"5476","volume":"47","author":"J Burchell","year":"1987","unstructured":"Burchell J, Gendler S, Taylor-Papadimitriou J, Girling A, Lewis A, Millis R, Lamport D (1987) Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res 47: 5476","journal-title":"Cancer Res"},{"key":"BF01789125_CR3","first-page":"207","volume-title":"Biomembranes, vol 2","author":"JF Codington","year":"1983","unstructured":"Codington JF, Frim DM (1983) Cell-surface macromolecular and morphological changes related to allotransplantability in the TA3 tumor. In: Manson LA (ed) Biomembranes, vol 2. Plenum, New York, p 207"},{"key":"BF01789125_CR4","first-page":"1029","volume":"73","author":"JF Codington","year":"1984","unstructured":"Codington JF, Bhavanandan VP, Bloch KJ, Nikrui N, Ellard JV, Wang PS, Jeanloz RW (1984) Antibody to epiglycanin and radioimmunoassay to detect epiglycanin-related glycoproteins in body fluids of cancer patients. JNCI 73: 1029","journal-title":"JNCI"},{"key":"BF01789125_CR5","first-page":"1170","volume":"51","author":"PS Fung","year":"1991","unstructured":"Fung PS, Longenecker BM (1991) Specific immunosuppressive activity of epiglycanin, a mucin-like glycoprotein secreted by a murine mammary adenocarcinoma (TA3-Ha). Cancer Res 51: 1170","journal-title":"Cancer Res"},{"key":"BF01789125_CR6","first-page":"4308","volume":"50","author":"PYS Fung","year":"1990","unstructured":"Fung PYS, Madej M, Koganty R, Longenecker BM (1990) Active specific immunotherapy of a murine mammary adenocarcinoma using a synthetic tumor-associated glycoconjugate. Cancer Res 50: 4308","journal-title":"Cancer Res"},{"key":"BF01789125_CR7","first-page":"1463","volume":"48","author":"S Friberg Jr","year":"1972","unstructured":"Friberg S Jr (1972) Comparison of an immunoresistant and an immunosusceptible ascites subline from murine tumor TA3: I. Transplantability, morphology and some physicochemical characteristics. JNCI 48: 1463","journal-title":"JNCI"},{"key":"BF01789125_CR8","doi-asserted-by":"crossref","first-page":"12 820","DOI":"10.1016\/S0021-9258(18)37632-4","volume":"263","author":"S Gendler","year":"1988","unstructured":"Gendler S, Taylor-Papadimitriou J, Duhig T, Rothbard J, Burchell J (1988) A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. Biol Chem 263: 12 820","journal-title":"Biol Chem"},{"key":"BF01789125_CR9","doi-asserted-by":"crossref","first-page":"15 286","DOI":"10.1016\/S0021-9258(18)77254-2","volume":"265","author":"SJ Gendler","year":"1990","unstructured":"Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, Duhig T, Peat N, Burchell J, Pemberton L, Lalani E-N, Wilson D (1990) Molecular cloning and expression of the human tumor-associated polymorphic epithelial mucin, PEM. Biol Chem 265: 15 286","journal-title":"Biol Chem"},{"key":"BF01789125_CR10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1515\/bchm3.1989.370.1.21","volume":"370","author":"F Hanisch","year":"1989","unstructured":"Hanisch F, Uhlenbruck G, Egge H, Peter-Katalinic J (1989) A B72.3 second-generation-monoclonal antibody (CC49) defines the mucincarried carbohydrate epitope Gal\u03b2(1\u20133)(NeuAc\u03b1(2\u20136))GalNAc. Biol Chem Hoppe-Seyler 370: 21","journal-title":"Biol Chem Hoppe-Seyler"},{"key":"BF01789125_CR11","doi-asserted-by":"crossref","first-page":"9498","DOI":"10.1073\/pnas.87.23.9498","volume":"87","author":"M Hareuveni","year":"1990","unstructured":"Hareuveni M, Gautier C, Kieny M-P, Wreschner D, Chambon P, Lathe R (1990) Vaccination against tumor cells expressing breast cancer epithelial tumor antigen. Proc Natl Acad Sci USA 87: 9498","journal-title":"Proc Natl Acad Sci USA"},{"key":"BF01789125_CR12","first-page":"231","volume":"25","author":"CM Henningson","year":"1987","unstructured":"Henningson CM, Selvaray S, MacLean GD, Suresh MR, Noujaim AA, Longenecker BM (1987) T cell recognition of tumorassociated glycoprotein and its synthetic carbohydrate epitopes: stimulation of anticancer T cell immunity in vivo. Cancer Immunol Immunother 25: 231","journal-title":"Cancer Immunol Immunother"},{"key":"BF01789125_CR13","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/eji.1830200304","volume":"20","author":"PC Ho","year":"1990","unstructured":"Ho PC, Muteh DA, Winkel KD, Saul AJ, Jones GL, Doran TJ, Rzepczyk CM (1990) Identification of two promiscuous T-cell epitopes from tetanus toxin. Eur J Immunol 20: 477","journal-title":"Eur J Immunol"},{"key":"BF01789125_CR14","first-page":"261","volume":"1","author":"SR Hull","year":"1989","unstructured":"Hull SR, Bright A, Carraway KL, Abe M, Hayes DF, Kufe D (1989) Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT-20 human breast carcinoma cell line. Cancer Commun 1: 261","journal-title":"Cancer Commun"},{"key":"BF01789125_CR15","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1002\/1097-0142(19901101)66:9<1960::AID-CNCR2820660919>3.0.CO;2-X","volume":"66","author":"SH Itzkowitz","year":"1990","unstructured":"Itzkowitz SH, Bloom EJ, Kokal WA, Modin G, Hakomori S-I, Kim YS (1990) Sialosyl-Tn: a novel mucin antigen associated with prognosis in colorectal cancer patients. Cancer 66: 1960","journal-title":"Cancer"},{"key":"BF01789125_CR16","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0968-0004(90)90014-3","volume":"15","author":"N Jentoff","year":"1990","unstructured":"Jentoff N (1990) Why are proteinsO-glycosylated? Trends Biochem Sci 15: 291","journal-title":"Trends Biochem Sci"},{"key":"BF01789125_CR17","first-page":"2908","volume":"51","author":"KR Jerome","year":"1991","unstructured":"Jerome KR, Barnd DL, Bendt KM, Boyer CM, Taylor-Papadimitriou J, McKenzie IFC, Bast RC Jr, Finn OJ (1991) Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the malignant cells. Cancer Res 51: 2908","journal-title":"Cancer Res"},{"key":"BF01789125_CR18","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.4049\/jimmunol.146.9.3235","volume":"146","author":"M Kahn","year":"1991","unstructured":"Kahn M, Sugawara H, McGowan P, Okuno K, Nagoya S, Hellstr\u00f6m KE, Hellstr\u00f6m I, Greenberg P (1991) CD4+ cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen. J Immunol 146: 3235","journal-title":"J Immunol"},{"key":"BF01789125_CR19","doi-asserted-by":"crossref","first-page":"8724","DOI":"10.1016\/S0021-9258(18)68365-6","volume":"263","author":"A Kurosaka","year":"1988","unstructured":"Kurosaka A, Kitagawa H, Fukui S, Numata Y, Nakada H, Funakoshi I, Kawasaki T, Ogawa T, Iijima H, Yamashina I (1988) A monoclonal antibody that recognizes a cluster of a disaccharide, NeuAc\u03b12-6GalNAc, in mucin-type glycoproteins. J Biol Chem 263: 8724","journal-title":"J Biol Chem"},{"key":"BF01789125_CR20","doi-asserted-by":"crossref","first-page":"15 420","DOI":"10.1016\/S0021-9258(18)98632-1","volume":"266","author":"E-N Lalani","year":"1991","unstructured":"Lalani E-N, Berdichevsky F, Boshell M, Shearer M, Wilson D, Stauss H, Gendler SJ, Taylor-Papadimitriou J (1991) Expression of the gene coding for a human mucin in mouse mammary tumour cells can affect their tumorigenicity. J Biol Chem 266: 15 420","journal-title":"J Biol Chem"},{"key":"BF01789125_CR21","doi-asserted-by":"crossref","first-page":"15 294","DOI":"10.1016\/S0021-9258(18)77255-4","volume":"265","author":"MS Lan","year":"1990","unstructured":"Lan MS, Batra SK, Qi W-N, Metzgar RS, Hollingsworth MA (1990) Cloning and sequencing of a human pancreatic tumor mucin cDNA. J Biol Chem 265: 15 294","journal-title":"J Biol Chem"},{"key":"BF01789125_CR22","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1159\/000217661","volume":"11","author":"GT Layton","year":"1990","unstructured":"Layton GT, Devine PL, Warren JA, Birrell G, Xing P-X, Ward BG, McKenzie IFC (1990) Monoclonal antibodies reactive with the breast carcinoma-associated mucin core protein repeat sequence peptide also recognize the ovarian carcinoma-associated sebaceous gland antigen. Tumor Biol 11: 274","journal-title":"Tumor Biol"},{"key":"BF01789125_CR23","unstructured":"MacLean G, Longenecker BM (1991) Novel synthetic immunother-apeutic vaccines for cancer: induction of hapten specific humoral immunity with reactivity with tumor cells. In: SBI '91 Biological Therapy of Cancer-VI Program and Abstracts. Society for Biological Therapy 1991 Annual Meeting, Pittsburgh, Pennsylvania"},{"key":"BF01789125_CR24","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1097\/00002371-199205000-00008","volume":"11","author":"GD MacLean","year":"1992","unstructured":"MacLean GD, Bowen-Yacyshyn MB, Samuel J, Meikle A, Stuart G, Nation J, Poppema S, Jerry M, Koganty R, Wong T, Longenecker BM (1992) Active immunization of human ovarian cancer patients against a common carcinoma (Thomsen-Friedenreich) determinant using a synthetic carbohydrate antigen. J Immunother 11: 292","journal-title":"J Immunother"},{"key":"BF01789125_CR25","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1083\/jcb.72.3.511","volume":"72","author":"SC Miller","year":"1977","unstructured":"Miller SC, Hay ED, Codington JF (1977) Ultrastructural and histochemical differences in cell surface properties of strain-specific and non-strain specific TA3 adenocarcinoma cells. J Cell Biol 72: 511","journal-title":"J Cell Biol"},{"key":"BF01789125_CR26","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0014-4827(90)90174-9","volume":"188","author":"G Parry","year":"1990","unstructured":"Parry G, Beck JC, Moss L, Bartley J, Ojakian GK (1990) Determination of apical membrane polarity in mammary epithelial cell cultures. The role of cell-cell, cell-substrate and membrane-cytoskeletal interaction. Exp Cell Res 188: 302","journal-title":"Exp Cell Res"},{"key":"BF01789125_CR27","first-page":"1954","volume":"52","author":"N Peat","year":"1992","unstructured":"Peat N, Gendler SJ, Lalani E-N, Duhig T, Taylor-Papadimitriou J (1992) Tissue specific expression of a human polymorphic epithelial mucin (MUC1) in transgenic mice. Cancer Res 52: 1954","journal-title":"Cancer Res"},{"key":"BF01789125_CR28","first-page":"4801","volume":"50","author":"J Samuel","year":"1990","unstructured":"Samuel J, Noujaim AA, MacLean GD, Suresh MR, Longenecker BM (1990) Analysis of human tumor-associated Thomsen-Friedenreich antigen. Cancer Res 50: 4801","journal-title":"Cancer Res"},{"key":"BF01789125_CR29","first-page":"1406","volume":"51","author":"A Singhal","year":"1991","unstructured":"Singhal A, Fohn M, Hakomori S (1991) Induction of \u03b1-N-acetylgalactosamine-O-serine\/threonine (Tn) antigen-mediated cellular immune response for active immunotherapy in mice. Cancer Res 51: 1406","journal-title":"Cancer Res"},{"key":"BF01789125_CR30","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/336778a0","volume":"336","author":"F Sinigaglia","year":"1988","unstructured":"Sinigaglia F, Guttinger M, Kilgus J, Doran DM, Martile H, Etlinger H, Trzeciak A, Gillessen D, Pink JRL (1988) A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules. Nature 336: 778","journal-title":"Nature"},{"key":"BF01789125_CR31","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1126\/science.6729450","volume":"224","author":"GF Springer","year":"1984","unstructured":"Springer GF (1984) T and Tn, general carcinoma autoantigens. Science 224: 1198","journal-title":"Science"},{"key":"BF01789125_CR32","first-page":"11","volume-title":"Cancer reviews. vol. 11\u201312","author":"J Taylor-Papdimitriou","year":"1988","unstructured":"Taylor-Papdimitriou J, Gendler SJ (1988) Molecular aspects of mucins. In: Hilgers J, Zotter S (eds) Cancer reviews. vol. 11\u201312. Munksgaard, Copenhagen, Denmark, p 11"},{"key":"BF01789125_CR33","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/ijc.2910450416","volume":"45","author":"F Torben","year":"1990","unstructured":"Torben F, Orntoft NH, Langkilde NC (1990)O-Linked mucin-type glycoproteins in normal and malignant colon mucosa: lack of T-antigen expression and accumulation of Tn and sialosyl-Tn antigens in carcinomas. Int J Cancer 45: 666","journal-title":"Int J Cancer"},{"key":"BF01789125_CR34","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.4049\/jimmunol.144.4.1455","volume":"144","author":"RCK Wong","year":"1990","unstructured":"Wong RCK, Remold-O'Donnell E, Vercelli D, Saneho J, Terhorst C, Rosen F, Geha R, Chatila T (1990) Signal transduction via leukocyte antigen CD43 (sialophorin). Feedback regulation by protein kinase C. J Immunol 144: 1455","journal-title":"J Immunol"}],"container-title":["Cancer Immunology, Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01789125.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF01789125\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01789125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01789125.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T16:14:09Z","timestamp":1684858449000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF01789125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["BF01789125"],"URL":"https:\/\/doi.org\/10.1007\/bf01789125","relation":{},"ISSN":["0340-7004","1432-0851"],"issn-type":[{"value":"0340-7004","type":"print"},{"value":"1432-0851","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1]]},"assertion":[{"value":"3 June 1992","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 1992","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}