{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:09:56Z","timestamp":1768676996146,"version":"3.49.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[1991,4,1]],"date-time":"1991-04-01T00:00:00Z","timestamp":670464000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur. J. Clin. Microbiol. Infect. Dis."],"published-print":{"date-parts":[[1991,4]]},"DOI":"10.1007\/bf01966994","type":"journal-article","created":{"date-parts":[[2005,7,30]],"date-time":"2005-07-30T07:43:34Z","timestamp":1122709414000},"page":"223-231","source":"Crossref","is-referenced-by-count":46,"title":["Mode of action of the new quinolones: New data"],"prefix":"10.1007","volume":"10","author":[{"given":"D. C.","family":"Hooper","sequence":"first","affiliation":[]},{"given":"J. S.","family":"Wolfson","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"issue":"Supplement 5","key":"BF01966994_CR1","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1093\/clinids\/11.Supplement_5.S902","volume":"11","author":"DC Hooper","year":"1989","unstructured":"Hooper DC, Wolfson JS Mode of action of the quinolone antimicrobial agents: review of recent information. Reviews of Infectious Diseases 1989, 11, Supplement 5: 902\u2013911.","journal-title":"Reviews of Infectious Diseases"},{"key":"BF01966994_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00338386","volume":"211","author":"H Yoshida","year":"1988","unstructured":"Yoshida H, Kojima T, Yamagishi J-I, Nakamura S Quinolone-resistant mutations of thegyrA gene ofEscherichia coli. Molecular and General Genetics 1988, 211: 1\u20137.","journal-title":"Molecular and General Genetics"},{"key":"BF01966994_CR3","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1128\/AAC.33.6.886","volume":"33","author":"ME Cullen","year":"1989","unstructured":"Cullen ME, Wyke AW, Kuroda R, Fisher LM Cloning and characterization of a DNA gyrase A gene fromEscherichia coli that confers clinical resistance to 4-quinolones. Antimicrobial Agents and Chemotherapy 1989, 33: 886\u2013894.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR4","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1128\/AAC.34.6.1271","volume":"34","author":"H Yoshida","year":"1990","unstructured":"Yoshida H, Bogaki M, Nakamura M, Nakamura S Quinolone resistance-determining region in the DNA gyrasegyrA gene ofEscherichia coli. Antimicrobial Agents and Chemotherapy 1990, 34: 1271\u20131272.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR5","doi-asserted-by":"crossref","first-page":"5339","DOI":"10.1016\/S0021-9258(18)61193-7","volume":"262","author":"DS Horowitz","year":"1987","unstructured":"Horowitz DS, Wang JC Mapping the active site tyrosine ofEscherichia coli DNA gyrase. Journal of Biological Chemistry 1987, 262: 5339\u20135344.","journal-title":"Journal of Biological Chemistry"},{"key":"BF01966994_CR6","doi-asserted-by":"crossref","first-page":"19648","DOI":"10.1016\/S0021-9258(19)47162-7","volume":"264","author":"RJ Reece","year":"1989","unstructured":"Reece RJ, Maxwell A Tryptic fragments of theEscherichia coli DNA gyrase A protein. Journal of Biological Chemistry 1989, 264: 19648\u201319653.","journal-title":"Journal of Biological Chemistry"},{"key":"BF01966994_CR7","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1093\/nar\/18.1.151","volume":"18","author":"GP Dimri","year":"1990","unstructured":"Dimri GP, Das HK Cloning and sequence analysis ofgyrA gene ofKlebsiella pneumoniae. Nucleic Acids Research 1990, 18: 151\u2013156.","journal-title":"Nucleic Acids Research"},{"key":"BF01966994_CR8","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1128\/jb.172.6.3481-3484.1990","volume":"172","author":"R Hopewell","year":"1990","unstructured":"Hopewell R, Oram M, Biresewitz R, Fisher LM DNA cloning and organization of theStaphylococcus aureus gyrA andgyrB genes: close homology among gyrase proteins and implications for 4-quinolone action and resistance. Journal of Bacteriology 1990, 172: 3481\u20133484.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR9","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1093\/nar\/13.7.2251","volume":"13","author":"S Moriya","year":"1985","unstructured":"Moriya S, Ogasawara N, Yoshikawa H Structure and function of the region of the replication origin of theBacillus subtilis chromosome. III: Nucleotide sequence of some 10,000 base pairs in the origin region. Nucleic Acids Research 1985, 13: 2251\u20132265.","journal-title":"Nucleic Acids Research"},{"key":"BF01966994_CR10","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF00331012","volume":"204","author":"JI Yamagishi","year":"1986","unstructured":"Yamagishi JI, Yoshida H, Yamayoshi M, Nakamura S Nalidixic acid-resistant mutations of thegyrB gene ofEscherichia coli. Molecular and General Genetics 1986, 204: 367\u2013373.","journal-title":"Molecular and General Genetics"},{"key":"BF01966994_CR11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0022-2836(88)90449-4","volume":"201","author":"RJ Franco","year":"1990","unstructured":"Franco RJ, Drlica K DNA gyrase on the bacterial chromosome. Oxolinic acid-induced DNA cleavage in thednaA-gyrB region. Journal of Molecular Biology 1990, 201: 229\u2013233.","journal-title":"Journal of Molecular Biology"},{"key":"BF01966994_CR12","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/BF00261192","volume":"219","author":"V Aleixandre","year":"1989","unstructured":"Aleixandre V, Urios A, Herrera G, Blanco M NewEscherichia coli gyrA andgyrB mutations which have a graded effect on DNA supercoiling. Molecular and General Genetics 1989, 219: 306\u2013312.","journal-title":"Molecular and General Genetics"},{"key":"BF01966994_CR13","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1101\/SQB.1983.047.01.087","volume":"47","author":"M Gellert","year":"1983","unstructured":"Gellert M, Menzel R, Mizuuchi K, O'Dea MH, Friedman D Regulation of DNA supercoiling inEscherichia coli. Cold Spring Harbor Symposia of Quantitative Biology 1983, 47: 763\u2013767.","journal-title":"Cold Spring Harbor Symposia of Quantitative Biology"},{"key":"BF01966994_CR14","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1073\/pnas.82.2.307","volume":"82","author":"LL Shen","year":"1985","unstructured":"Shen LL, Pernet AG Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA. Proceedings of the National Academy of Sciences of the USA 1985, 82: 307\u2013311.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"BF01966994_CR15","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1016\/S0021-9258(19)81708-8","volume":"264","author":"LL Shen","year":"1989","unstructured":"Shen LL, Kohlbrenner WE, Weigl D, Baranowski J Mechanism of quinolone inhibition of DNA gyrase. Journal of Biological Chemistry 1989, 264: 2973\u20132978.","journal-title":"Journal of Biological Chemistry"},{"key":"BF01966994_CR16","doi-asserted-by":"crossref","first-page":"3879","DOI":"10.1021\/bi00435a038","volume":"28","author":"LL Shen","year":"1989","unstructured":"Shen LL, Baranowski J, Pernet AG Mechanism of inhibition of DNA gyrase by quinolone antibacterials: specificity and cooperativity of drug binding to DNA. Biochemistry 1989, 28: 3879\u20133885.","journal-title":"Biochemistry"},{"key":"BF01966994_CR17","doi-asserted-by":"crossref","first-page":"3886","DOI":"10.1021\/bi00435a039","volume":"28","author":"LL Shen","year":"1989","unstructured":"Shen LL, Mitscher LA, Sharma PN, O'Donnell TJ, Chu DTW, Cooper CS, Rosen T, Pernet AG Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model. Biochemistry 1989, 28: 3886\u20133894.","journal-title":"Biochemistry"},{"key":"BF01966994_CR18","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/BF01977492","volume":"3","author":"JT Smith","year":"1984","unstructured":"Smith JT Mutational resistance to 4-quinolone antibacterial agents. European Journal of Clinical Microbiology 1984, 3: 347\u2013350.","journal-title":"European Journal of Clinical Microbiology"},{"key":"BF01966994_CR19","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/AAC.29.6.1073","volume":"29","author":"P Hussy","year":"1986","unstructured":"Hussy P, Maass G, Tummler B, Grosse F, Schomburg U Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase \u03b1 primase, topoisomerases I and II, and growth of mammalian lymphoblasts. Antimicrobial Agents and Chemotherapy 1986, 29: 1073\u20131078.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR20","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1128\/AAC.33.10.1816","volume":"33","author":"K Hoshino","year":"1989","unstructured":"Hoshino K, Sato K, Une T, Osada Y Inhibitory effects of quinolones on DNA gyrase ofEscherichia coli and topoisomerase II of fetal calf thymus. Antimicrobial Agents and Chemotherapy 1989, 33: 1816\u20131818.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR21","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1128\/AAC.33.10.1697","volume":"33","author":"JF Barrett","year":"1989","unstructured":"Barrett JF, Gootz TD, McGuirk PR, Farrell CA, Sokolowski SA Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents. Antimicrobial Agents and Chemotherapy 1989, 33: 1697\u20131703.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR22","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/em.2850130308","volume":"13","author":"HE Holden","year":"1989","unstructured":"Holden HE, Barrett JF, Huntington CM, Muehlbauer PA, Wahrenburg MG Genetic profile of a nalidixic acid analog: a model for the mechanism of sister chromatid exchange induction. Environmental and Molecular Mutagenesis 1989, 13: 238\u2013252.","journal-title":"Environmental and Molecular Mutagenesis"},{"key":"BF01966994_CR23","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1128\/AAC.32.8.1113","volume":"32","author":"RT Chow","year":"1988","unstructured":"Chow RT, Dougherty TJ, Fraimow HS, Belin EY, Miller MH Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA]Escherichia coli K-12. Antimicrobial Agents and Chemotherapy 1988, 32: 1113\u20131118.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR24","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1128\/AAC.34.6.1088","volume":"34","author":"LJV Piddock","year":"1990","unstructured":"Piddock LJV, Hall MC, Wise R Mechanism of action of lomefloxacin. Antimicrobial Agents and Chemotherapy 1990, 34: 1088\u20131093.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR25","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1128\/AAC.33.9.1457","volume":"33","author":"J Bedard","year":"1989","unstructured":"Bedard J, Chamberland S, Wong S, Schollaardt T, Bryan LE Contribution of permeability and sensitivity to inhibition of DNA synthesis in determining susceptibilities toEscherichia coli, Pseudomonas aeruginosa, andAlcaligenes faecalis to ciprofloxacin. Antimicrobial Agents and Chemotherapy 1989, 33: 1457\u20131464.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR26","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1128\/JB.149.1.92-98.1982","volume":"149","author":"EC Engle","year":"1982","unstructured":"Engle EC, Manes SH, Drlica K Differential effects of antibiotics inhibiting gyrase. Journal of Bacteriology 1982, 149: 92\u201398.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR27","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1128\/AAC.34.6.1273","volume":"34","author":"H Yoshida","year":"1990","unstructured":"Yoshida H, Nakamura M, Bogaki M, Nakamura S Proportion of DNA gyrase mutants among quinolone-resistant strains ofPseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 1990, 34: 1273\u20131275.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR28","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1128\/AAC.30.5.777","volume":"30","author":"K Sato","year":"1986","unstructured":"Sato K, Inoue Y, Fujii T, Aoyama H, Inoue M, Mitsuhashi S Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain ofEscherichia coli. Antimicrobial Agents and Chemotherapy 1986, 30: 777\u2013780.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR29","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1128\/jb.169.5.2322-2325.1987","volume":"169","author":"Y Inoue","year":"1987","unstructured":"Inoue Y, Sato K, Fujii T, Hirai K, Inoue M, Iyobe S, Mitsuhashi S Some properties of subunits of DNA gyrase fromPseudomonas aeruginosa PA01 and its nalidixic acid-resistant mutant. Journal of Bacteriology 1987, 169: 2322\u20132325.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR30","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/978-1-4471-3449-7_8","volume-title":"The 4-quinolones. Antibacterial agents in vitro","author":"NJ Robillard","year":"1990","unstructured":"Robillard NJ, Masecar BL, Brescia B, Celesk R Comparisons of DNA gyrases from different species. In: Crumplin GC (ed): The 4-quinolones. Antibacterial agents in vitro. Springer Verlag, London, 1990, p. 103\u2013114."},{"key":"BF01966994_CR31","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1128\/JB.91.2.768-773.1966","volume":"91","author":"WH Dietz","year":"1966","unstructured":"Dietz WH, Cook TM, Goss WA Mechanism of action of nalidixic acid onEscherichia coli. III: Conditions required for lethality. Journal of Bacteriology 1966, 91: 768\u2013773.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/978-1-4471-3449-7_3","volume-title":"The 4-quinolones. Antibacterial agents in vitro","author":"I Morrissey","year":"1990","unstructured":"Morrissey I, Lewin CS, Smith JT The influence of oxygen upon bactericidal potency. In: Crumplin GC (ed): The 4-quinolones. Antibacterial agents in vitro. Springer Verlag, London, 1990, p. 23\u201336."},{"key":"BF01966994_CR33","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/BF01963763","volume":"8","author":"CS Lewin","year":"1989","unstructured":"Lewin CS, Amyes SGB, Smith JT Bactericidal activity of enoxacin and lomefloxacin againstEscherichia coli KL16. European Journal of Clinical Microbiology and Infectious Diseases 1989, 8: 731\u2013733.","journal-title":"European Journal of Clinical Microbiology and Infectious Diseases"},{"key":"BF01966994_CR34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-1-4471-3449-7_6","volume-title":"The 4-quinolones. Antibacterial agents in vitro","author":"JS Wolfson","year":"1990","unstructured":"Wolfson JS, Hooper DC Mechanisms of killing of bacteria by 4-quinolones. In: Crumplin GC (ed): The 4-quinolones. Antibacterial agents in vitro. Springer Verlag, London, 1990, p. 69\u201385."},{"key":"BF01966994_CR35","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/978-1-4471-3449-7_4","volume-title":"The 4-quinolones. Antibacterial agents in vitro","author":"CS Lewin","year":"1990","unstructured":"Lewin CS, Smith JT Interactions of 4-quinolones with other agents \u2014 the importance in assessing practical antibacterial potency. In: Crumplin GC (ed): The 4-quinolones. Antibacterial agents in vitro. Springer Verlag, London, 1990, p. 37\u201351."},{"key":"BF01966994_CR36","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.1574-6968.1987.tb02213.x","volume":"41","author":"LJV Piddock","year":"1987","unstructured":"Piddock LJV, Wise R Induction of the SOS response by new 4-quinolones. FEMS Microbiology Letters 1987, 41: 289\u2013294.","journal-title":"FEMS Microbiology Letters"},{"key":"BF01966994_CR37","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1093\/jac\/20.5.631","volume":"20","author":"I Phillips","year":"1987","unstructured":"Phillips I, Culebras E, Moreno F, Baquero F Induction of the SOS response by new 4-quinolones. Journal of Antimicrobial Chemotherapy 1987, 20: 631\u2013638.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF01966994_CR38","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(82)90085-X","volume":"29","author":"JW Little","year":"1982","unstructured":"Little JW, Mount DW The SOS regulatory system ofEscherichia coli. Cell 1982, 29: 11\u201322.","journal-title":"Cell"},{"key":"BF01966994_CR39","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0022-2836(90)90306-7","volume":"212","author":"M Sassanfar","year":"1990","unstructured":"Sassanfar M, Roberts JW Nature of the SOS-inducing signal inEscherichia coli. The involvement of DNA replication. Journal of Molecular Biology 1990, 212: 79\u201396.","journal-title":"Journal of Molecular Biology"},{"key":"BF01966994_CR40","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/nar\/14.3.1149","volume":"14","author":"E Cassuto","year":"1986","unstructured":"Cassuto E, Howard-Flanders P The binding of RecA protein to duplex DNA molecules is directional and is promoted by a single-stranded region. Nucleic Acids Research 1986, 14: 1149\u20131157.","journal-title":"Nucleic Acids Research"},{"key":"BF01966994_CR41","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1073\/pnas.75.4.1773","volume":"75","author":"LJ Gudas","year":"1978","unstructured":"Gudas LJ, Pardee AB Model for regulation ofEscherichia coli DNA repair functions. Proceedings of the National Academy of Sciences of the USA 1978, 75: 1773\u20131777.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"BF01966994_CR42","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1128\/JB.134.3.1195-1198.1978","volume":"134","author":"LS McDaniel","year":"1978","unstructured":"McDaniel LS, Rogers LH, Hill WE Survival of recombination-deficient mutants ofEscherichia coli during incubation with nalidixic acid. Journal of Bacteriology 1978, 134: 1195\u20131198.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR43","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1099\/00222615-29-2-139","volume":"29","author":"CS Lewin","year":"1989","unstructured":"Lewin CS, Howard BMA, Ratcliffe NT, Smith JT 4-quinolones and the SOS response. Journal of Medical Microbiology 1989, 29: 139\u2013144.","journal-title":"Journal of Medical Microbiology"},{"key":"BF01966994_CR44","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1093\/jac\/24.6.863","volume":"24","author":"RN Walters","year":"1989","unstructured":"Walters RN, Piddock LJV, Wise R The effect of mutations in the SOS response on the kinetics of quinolone killing. Journal of Antimicrobial Chemotherapy 1989, 24: 863\u2013873.","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"BF01966994_CR45","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1128\/JB.163.2.688-695.1985","volume":"163","author":"ES Tessman","year":"1985","unstructured":"Tessman ES, Peterson PK Isolation of protease-proficient, recombinase-deficientrecA mutants ofEscherichia coli K-12. Journal of Bacteriology 1985, 163: 688\u2013695.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR46","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1128\/JB.91.2.774-779.1966","volume":"91","author":"TM Cook","year":"1966","unstructured":"Cook TM, Dietz WH, Goss WA Mechanism of action of nalidixic acid onEscherichia coli. IV: Effects on the stability of cellular constituents. Journal of Bacteriology 1966, 91: 774\u2013779.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR47","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1099\/00222615-31-1-65","volume":"31","author":"CA Lewin","year":"1990","unstructured":"Lewin CA, Smith JT DNA breakdown by the 4-quinolones and its significance. Journal of Medical Microbiology 1990, 31:65\u201370.","journal-title":"Journal of Medical Microbiology"},{"key":"BF01966994_CR48","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1432-1033.1987.tb11172.x","volume":"164","author":"C Ronda","year":"1987","unstructured":"Ronda C, Garcia JL, Garcia E, Sanchez-Puelles JM, Lopez R Biological role of pneumococcal amidase. Cloning of thelytA gene inStreptococcus pneumoniae. European Journal of Biochemistry 1987, 164: 621\u2013624.","journal-title":"European Journal of Biochemistry"},{"key":"BF01966994_CR49","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1128\/JB.155.2.768-775.1983","volume":"155","author":"HS Moyed","year":"1983","unstructured":"Moyed HS, Bertrand KP hipA, a newly recognized gene ofEscherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. Journal of Bacteriology 1983, 155: 768\u2013775.","journal-title":"Journal of Bacteriology"},{"key":"BF01966994_CR50","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1128\/AAC.34.10.1938","volume":"34","author":"JS Wolfson","year":"1990","unstructured":"Wolfson JS, Hooper DC, McHugh GL, Bozza MA, Swartz MN Mutants ofEscherichia coli K-12 exhibiting reduced killing by both quinolone and \u03b2-lactam antimicrobial agents. Antimicrobial Agents and Chemotherapy 1990, 34: 1938\u20131943.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR51","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1128\/AAC.33.5.705","volume":"33","author":"JS Wolfson","year":"1989","unstructured":"Wolfson JS, Hooper DC, Shih DJ, McHugh GL, Swartz MN Isolation and characterization of anEscherichia coli strain exhibiting partial tolerance to quinolones. Antimicrobial Agents and Chemotherapy 1989, 33: 705\u2013709.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"BF01966994_CR52","doi-asserted-by":"crossref","first-page":"3321","DOI":"10.1128\/jb.170.8.3321-3326.1988","volume":"170","author":"R Scherrer","year":"1988","unstructured":"Scherrer R, Moyed HS Conditional impairment of cell division and altered lethality inhipA mutants ofEscherichia coli K-12. Journal of Bacteriology 1988, 170: 3321\u20133326.","journal-title":"Journal of Bacteriology"}],"container-title":["European Journal of Clinical Microbiology & Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01966994.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF01966994\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF01966994","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T07:19:07Z","timestamp":1626247147000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF01966994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,4]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1991,4]]}},"alternative-id":["BF01966994"],"URL":"https:\/\/doi.org\/10.1007\/bf01966994","relation":{},"ISSN":["0934-9723","1435-4373"],"issn-type":[{"value":"0934-9723","type":"print"},{"value":"1435-4373","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,4]]}}}