{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T07:01:32Z","timestamp":1762671692650},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[1977,12,1]],"date-time":"1977-12-01T00:00:00Z","timestamp":249782400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Calc. Tis Res."],"published-print":{"date-parts":[[1977,12]]},"DOI":"10.1007\/bf02010363","type":"journal-article","created":{"date-parts":[[2005,8,11]],"date-time":"2005-08-11T16:29:08Z","timestamp":1123777748000},"page":"243-252","source":"Crossref","is-referenced-by-count":43,"title":["Ethane-1-hydroxy-1,1-diphosphonate (EHDP) effects on incorporation and accumulation of osteoclast nuclei"],"prefix":"10.1007","volume":"22","author":[{"given":"Scott C.","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Webster S. S.","family":"Jee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald B.","family":"Kimmel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lowell","family":"Woodbury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02010363_CR1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1677\/joe.0.0450387","volume":"45","author":"P. G. Bingham","year":"1969","unstructured":"Bingham, P. G., Brazell, I. A., Owen, M.: The effect of parathyroid extract on cellular activity and plasma calcium levels in vivo. J. Endocr.45, 387\u2013400 (1969)","journal-title":"J. Endocr."},{"key":"BF02010363_CR2","first-page":"243","volume-title":"Statistics in biology, Vol. 1","author":"C. I. Bliss","year":"1967","unstructured":"Bliss, C. I.: Statistics in biology, Vol. 1, pp. 243\u2013247. New York: McGraw-Hill 1967"},{"key":"BF02010363_CR3","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1038\/2141269a0","volume":"214","author":"J. M. Faccini","year":"1967","unstructured":"Faccini, J. M.: Inhibition of bone resorption in the rabbit by fluoride. Nature (Lond.)214, 1269\u20131271 (1967)","journal-title":"Nature (Lond.)"},{"key":"BF02010363_CR4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02058641","volume":"3","author":"J. M. Faccini","year":"1969","unstructured":"Faccini, J. M.: Fluoride and bone. Calcif. Tiss. Res.3, 1\u201316 (1969)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR5","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/ar.1091430402","volume":"143","author":"D. A. Fischman","year":"1962","unstructured":"Fischman, D. A., Hay, E. D.: Origin of osteoclasts from mononuclear leukocytes in regenerating newt limbs. Anat. Rec.143, 329\u2013337 (1962)","journal-title":"Anat. Rec."},{"key":"BF02010363_CR6","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1126\/science.165.3899.1262","volume":"165","author":"H. Fleisch","year":"1969","unstructured":"Fleisch, H., Russell, R. G. G., Francis, M. D.: Diphosphonate inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science165, 1262\u20131264 (1969)","journal-title":"Science"},{"key":"BF02010363_CR7","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/BF02017544","volume":"5","author":"I. Gedilia","year":"1970","unstructured":"Gedilia, I., Hodge, H. C., Anaise, J., White, W. E., Menczel, J.: The effect of sodium monofluorophosphate and sodium fluoride on bone immobilization in rats. Calcif. Tiss. Res.5, 146\u2013152 (1970)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR8","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF02894009","volume":"12","author":"G. Gothlin","year":"1973","unstructured":"Gothlin, G., Ericsson, J. L. E.: On the histogenesis of the cells in fracture callus. Electron microscope autoradiographic observations in parabiotic rats and studies on labeled monocytes. Virchows Arch. Abt. B Zellpath.12, 318\u2013329 (1973)","journal-title":"Virchows Arch. Abt. B Zellpath."},{"key":"BF02010363_CR9","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF02059065","volume":"15","author":"D. F. Guilland","year":"1974","unstructured":"Guilland, D. F., Sallis, J. D., Fleisch, H.: The effect of two diphosphonates on the handling of calcium by rat kidney mitochondria in vitro. Calcif. Tiss. Res.15, 303\u2013314 (1974)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ar.1091830102","volume":"183","author":"B. K. Hall","year":"1975","unstructured":"Hall, B. K.: The origin and fate of osteoclasts. Anat. Rec.183, 1\u201311 (1975)","journal-title":"Anat. Rec."},{"key":"BF02010363_CR11","first-page":"643","volume-title":"The health effects of plutonium and radium","author":"E. Hashimoto","year":"1976","unstructured":"Hashimoto, E., Jee, W. S. S.: Cells at risk from bone-seeking radionuclides. A review. In: The health effects of plutonium and radium, pp. 643\u2013656 (W. S. S. Jee, ed.). Salt Lake City: J. W. Press 1976"},{"key":"BF02010363_CR12","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/200225a0","volume":"200","author":"W. S. S. Jee","year":"1963","unstructured":"Jee, W. S. S., Nolan, P. D.: Origin of osteoclasts from the fusion of phagocytes. Nature (Lond.)200, 225\u2013226 (1963)","journal-title":"Nature (Lond.)"},{"key":"BF02010363_CR13","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1302\/0301-620X.42B4.824","volume":"43B","author":"N. F. Kember","year":"1960","unstructured":"Kember, N. F.: Cell division and endochondral ossification. A study of cell proliferation in rat bones by the method of tritiated thymidine autoradiography. J. Bone Jt Surg.43B, 824\u2013839 (1960)","journal-title":"J. Bone Jt Surg."},{"key":"BF02010363_CR14","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3109\/10520297509117039","volume":"50","author":"D. B. Kimmel","year":"1975","unstructured":"Kimmel, D. B., Jee, W. S. S.: A rapid plastic embedding technique for three micron thick sections of decalcified hard tissue. Stain Technol.50, 83\u201386 (1975)","journal-title":"Stain Technol."},{"key":"BF02010363_CR15","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF02546413","volume":"20","author":"J. F. Loutit","year":"1976","unstructured":"Loutit, J. F., Sansom, J. M.: Osteopetrosis of microphthalmic mice\u2014A defect of the hematopoietic stem cell? Calcif. Tiss. Res.20, 251\u2013259 (1976)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR16","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/B978-0-12-648360-4.50085-7","volume-title":"Extracellular matrix influences on gene expression","author":"J. L. Matthews","year":"1975","unstructured":"Matthews, J. L., Davis, W. L., Martin, J. H., Talmage, R.: The endosteal cell response to exogenous stimuli, an electron microscope study. In: Extracellular matrix influences on gene expression, pp. 735\u2013744 (H. C. Slavkin and R. C. Greulich, eds.). New York: Academic Press 1975"},{"key":"BF02010363_CR17","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/aja.1001060305","volume":"106","author":"B. Messier","year":"1960","unstructured":"Messier, B., Leblond, C. P.: Cell proliferation and migration as revealed by radioautography after injection of thymidine-H3 into male rats and mice. Amer. J. Anat.106, 247\u2013285 (1960)","journal-title":"Amer. J. Anat."},{"key":"BF02010363_CR18","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/BF02546241","volume":"18","author":"S. C. Miller","year":"1975","unstructured":"Miller, S. C., Jee, W. S. S.: Ethane-1-hydroxy-1,1-diphosphonate (EHDP) effects on growth and modeling of the rat tibia. Calcif. Tiss. Res.18, 215\u2013231 (1975)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0074-7696(08)62544-9","volume":"28","author":"M. Owen","year":"1970","unstructured":"Owen, M.: The origin of bone cells. Int. Rev. Cytol.28, 213\u2013238 (1970)","journal-title":"Int. Rev. Cytol."},{"key":"BF02010363_CR20","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/0003-9969(63)90071-2","volume":"8","author":"A. S. Posner","year":"1963","unstructured":"Posner, A. S., Eanes, E. D., Harper, R. A., Zipkin, I.: X-ray diffraction analysis of the effect of fluoride on human bone apatite. Arch. oral Biol.8, 549\u2013556 (1963)","journal-title":"Arch. oral Biol."},{"key":"BF02010363_CR21","first-page":"66","volume":"55B","author":"R. G. G. Russell","year":"1973","unstructured":"Russell, R. G. G., Smith, R.: Diphosphonates: experimental and clinical aspects. J. Bone Jt Surg.55B, 66\u201386 (1973)","journal-title":"J. Bone Jt Surg."},{"key":"BF02010363_CR22","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00003086-197505000-00038","volume":"108","author":"R. G. G. Russell","year":"1975","unstructured":"Russell, R. G. G., Fleisch, H.: Pyrophosphate and diphosphonates in skeletal metabolism. Clin. Orthop.108, 241\u2013263 (1975)","journal-title":"Clin. Orthop."},{"key":"BF02010363_CR23","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/BF02547219","volume":"11","author":"R. Schenk","year":"1973","unstructured":"Schenk, R., Merz, W. A., Fleisch, H. A., Muhlbauer, R. C., Russell, R. G. G.: Effects of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl2MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats. Calcif. Tiss. Res.11, 196\u2013214 (1973)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR24","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0016-6480(62)90045-X","volume":"2","author":"R. V. Talmage","year":"1962","unstructured":"Talmage, R. V., Doty, S. D.: The effect of sodium fluoride on parathyroid function in the rat as studied by peritoneal lavage. Gen. comp. Endocr.2, 473\u2013479 (1962)","journal-title":"Gen. comp. Endocr."},{"key":"BF02010363_CR25","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF02547224","volume":"11","author":"A. Tatevossian","year":"1973","unstructured":"Tatevossian, A.: Effect of parathyroid extract on blood calcium and osteoclast count in mice. Calcif. Tiss. Res.11, 251\u2013257 (1973)","journal-title":"Calcif. Tiss. Res."},{"key":"BF02010363_CR26","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3181\/00379727-103-25612","volume":"103","author":"R. F. Toft","year":"1960","unstructured":"Toft, R. F., Talmage, R. V.: Quantitative relationship of osteoclasts to parathyroid function. Proc. Soc. exp. Biol. (N. Y.)103, 611\u2013613 (1960)","journal-title":"Proc. Soc. exp. Biol. (N. Y.)"},{"key":"BF02010363_CR27","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/00003086-197209000-00040","volume":"87","author":"E. A. Tonna","year":"1972","unstructured":"Tonna, E. A.: An electron microscope study of osteocyte release during osteoclasis in mice of different ages. Clin. Orthop.87, 311\u2013317 (1972)","journal-title":"Clin. Orthop."},{"key":"BF02010363_CR28","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1302\/0301-620X.45B2.402","volume":"45B","author":"J. Trueta","year":"1963","unstructured":"Trueta, J.: The role of vessels in osteogenesis. J. Bone Jt Surg.45B, 402\u2013418 (1963)","journal-title":"J. Bone Jt Surg."},{"key":"BF02010363_CR29","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1126\/science.180.4088.875","volume":"180","author":"D. G. Walker","year":"1973","unstructured":"Walker, D. G.: Osteopetrosis in mice cured by temporary parabiosis. Science180, 875 (1973)","journal-title":"Science"},{"key":"BF02010363_CR30","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1084\/jem.142.3.651","volume":"142","author":"D. G. Walker","year":"1975","unstructured":"Walker, D. G.: Control of bone resorption by hemapoietic tissue. The induction and reversal of congenital osteopetrosis in mice through use of bone marrow and spleen transplants. J. exp. Med.142, 651\u2013663 (1975)","journal-title":"J. exp. Med."},{"key":"BF02010363_CR31","first-page":"293","volume":"9","author":"J. A. Yee","year":"1976","unstructured":"Yee, J. A., Kimmel, D. B., Jee, W. S. S.: Periodontal ligament cell kinetics following orthodontic tooth movement. Cell Tiss. Kinet.9, 293\u2013302 (1976)","journal-title":"Cell Tiss. Kinet."},{"key":"BF02010363_CR32","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1083\/jcb.14.3.357","volume":"14","author":"R. W. Young","year":"1962","unstructured":"Young, R. W.: Cell proliferation and specialization during endochondral osteogenesis in young rats. J. Cell Biol.14, 357\u2013370 (1962)","journal-title":"J. Cell Biol."}],"container-title":["Calcified Tissue Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02010363.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02010363\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02010363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T03:59:18Z","timestamp":1683172758000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02010363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,12]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1977,12]]}},"alternative-id":["BF02010363"],"URL":"https:\/\/doi.org\/10.1007\/bf02010363","relation":{},"ISSN":["0008-0594","1432-0827"],"issn-type":[{"value":"0008-0594","type":"print"},{"value":"1432-0827","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,12]]}}}