{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:21:03Z","timestamp":1769214063266,"version":"3.49.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2005,8,1]],"date-time":"2005-08-01T00:00:00Z","timestamp":1122854400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Biol. Eng. Comput."],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1007\/bf02344727","type":"journal-article","created":{"date-parts":[[2006,3,15]],"date-time":"2006-03-15T11:57:12Z","timestamp":1142423832000},"page":"465-472","source":"Crossref","is-referenced-by-count":15,"title":["How to select the elastic modulus for cancellous bone in patient-specific continuum models of the spine"],"prefix":"10.1007","volume":"43","author":[{"given":"I.","family":"Diamant","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Shahar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gefen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02344727_CR1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/ar.1060","volume":"265","author":"B. Borah","year":"2001","unstructured":"Borah, B., Gross, G. J., Dufresne, T. E., Smith, T. S., Cockman, M. D., Chmielewski, P. A., Lundy, M. W., Harke, J. R., andSod, E. W. (2001). \u2018Three-dimensional microimaging (MR\u03bcI and \u03bcCT), finite element modeling, and rapid prototyping provide unique insights into bone architecture in osteoporosis\u2019,Med. Anat. Rec.,265, pp. 101\u2013110","journal-title":"Med. Anat. Rec."},{"key":"BF02344727_CR2","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1152\/jappl.2000.89.6.2359","volume":"89","author":"S. K. Boyd","year":"2000","unstructured":"Boyd, S. K., Matyas, J. R., Wohl, G. R., Kantzas, A., andZernicke, R. F. (2000): \u2018Early regional adaptation of periarticular bone mineral density after anterior cruciate ligament injury\u2019,J. Appl. Physiol.,89, pp. 2359\u20132364","journal-title":"J. Appl. Physiol."},{"key":"BF02344727_CR3","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/S8756-3282(03)00210-2","volume":"33","author":"R. P. Crawford","year":"2003","unstructured":"Crawford, R. P., Cann, C. E., andKeaveny, T. M. (2003a): \u2018Finite element models predictin vitro vertebral body compressive strength better than quantitative compute tomography\u2019,Bone 33, pp. 744\u2013750","journal-title":"Bone"},{"key":"BF02344727_CR4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1115\/1.1589772","volume":"125","author":"R. P. Crawford","year":"2003","unstructured":"Crawford, R. P., Rosenberg, W. S., andKeaveny, T. M. (2003b): \u2018Quantitative computed tomography-based finite element models of the human lumbar vertebral body: effect of element size on stiffness, damage, and fracture strength predictions\u2019,J. Biomech. Eng.,125, pp. 434\u2013438","journal-title":"J. Biomech. Eng."},{"key":"BF02344727_CR5","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/BF02350998","volume":"42","author":"D. Dagan","year":"2004","unstructured":"Dagan, D., Be'ery, M., andGefen, A. (2004): \u2018Single-trabecula building block for large-scale finite element models of cancellous bone\u2019,Med. Biol. Eng. Comput.,42, pp. 549\u2013556","journal-title":"Med. Biol. Eng. Comput."},{"key":"BF02344727_CR6","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/00003086-200408000-00035","volume":"425","author":"T. Damrongrungruang","year":"2004","unstructured":"Damrongrungruang, T., Kuroda, S., Kondo, H., Aoki, K., Ohya, K., andKasugai, S. (2004): \u2018A simple murine model for immobilization osteopenia\u2019,Clin. Orthop.,425, pp. 244\u2013251","journal-title":"Clin. Orthop."},{"key":"BF02344727_CR7","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1359\/jbmr.2003.18.9.1622","volume":"18","author":"V. David","year":"2003","unstructured":"David, V., Laroche, N., Boudignon, B., Lafage-Proust, M. H., Alexandre, C., Ruegsegger, P., andVico, L. (2003): \u2018Noninvasivein vivo monitoring of bone architecture alterations in hindlimb-unloaded female rats using novel three-dimensional microcomputed tomography\u2019,J. Bone Miner. Res.,18, pp. 1622\u20131631","journal-title":"J. Bone Miner. Res."},{"key":"BF02344727_CR8","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0736-0266(03)00112-8","volume":"21","author":"K. Ditsios","year":"2003","unstructured":"Ditsios, K., Boyer, M. I., Kusano, N., Gelberman, R. H., andSilva, M. J. (2003). \u2018Bone loss following tendon laceration, repair and passive mobilization\u2019,J. Orthop. Res.,21, pp. 990\u2013996","journal-title":"J. Orthop. Res."},{"key":"BF02344727_CR9","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/00004728-199101000-00021","volume":"15","author":"E. P. Durand","year":"1991","unstructured":"Durand, E. P. andRuegsegger, P. (1991). \u2018Cancellous bone structure: analysis of high-resolution CT images with the run-length method\u2019,J. Comput. Assist. Tomogr.,15, pp. 133\u2013139","journal-title":"J. Comput. Assist. Tomogr."},{"key":"BF02344727_CR10","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1359\/jbmr.1999.14.8.1394","volume":"14","author":"E. N. Ebbesen","year":"1999","unstructured":"Ebbesen, E. N., Thomsen, J. S., Beck-Nielsen, H., Nepper-Rasmussen, H. J., andMosekilde, L. I. (1999). \u2018Age- and gender-related differences in vertebral bone mass density and strength\u2019,J. Bone. Miner. Res.,14, pp. 1394\u20131403","journal-title":"J. Bone. Miner. Res."},{"key":"BF02344727_CR11","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1243\/09544110260216568","volume":"216","author":"M. J. Fagan","year":"2002","unstructured":"Fagan, M. J., Julian, S., andMohsen, A. M. (2002): \u2018Finite element analysis in spine research\u2019,Proc. Inst. Mech. Eng. (H).,216, pp. 281\u2013298","journal-title":"Proc. Inst. Mech. Eng. (H)."},{"key":"BF02344727_CR12","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1007\/s00586-003-0621-0","volume":"12","author":"S. J. Ferguson","year":"2003","unstructured":"Ferguson, S. J., andSteffen, T. (2003): \u2018Biomechanics of the aging spine\u2019,Eur. Spine J.,12, pp. S97-S103","journal-title":"Eur. Spine J."},{"key":"BF02344727_CR13","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/jor.1100040307","volume":"4","author":"D. P. Fyhrie","year":"1986","unstructured":"Fyhrie, D. P., andCarter, D. R. (1986): \u2018A unifying principle relating stress to trabecular bone morphology\u2019,J. Orthop. Res.,4, pp. 304\u2013317","journal-title":"J. Orthop. Res."},{"key":"BF02344727_CR14","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s001980050070","volume":"8","author":"C. L. Gordon","year":"1998","unstructured":"Gordon, C. L., Lang, T. F., Augat, P., andGenant, H. K. (1998): \u2018Image-based assessment of spinal trabecular bone structure from high-resolution CT images\u2019,Osteoporos Int.,8, pp. 317\u2013325","journal-title":"Osteoporos Int."},{"key":"BF02344727_CR15","first-page":"185","volume":"12","author":"X. E. Guo","year":"1997","unstructured":"Guo, X. E., andGoldstein, S. A. (1997): \u2018Is trabecular bone tissue different from cortical bone tissue?\u2019Forma,12, pp. 185\u2013196","journal-title":"Forma"},{"key":"BF02344727_CR16","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0021-9290(88)90257-6","volume":"21","author":"T. P. Harrigan","year":"1988","unstructured":"Harrigan, T. P., Jasty, M., Mann, R. W., andHarris, W. H. (1988): \u2018Limitations of the continuum assumption in cancellous bone\u2019,J. Biomech.,21, pp. 269\u2013275","journal-title":"J. Biomech."},{"key":"BF02344727_CR17","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0021-9290(98)00110-9","volume":"31","author":"F. J. Hou","year":"1998","unstructured":"Hou, F. J., Lang, S. M., Hoshaw, S. J., Reimann, D. A., andFyhrie, D. P. (1998): \u2018Human vertebral body apparent and hard tissue stiffness\u2019,J. Biomech.,31, pp. 1009\u20131015","journal-title":"J. Biomech."},{"key":"BF02344727_CR18","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.bone.2004.09.007","volume":"35","author":"D. G. Kim","year":"2004","unstructured":"Kim, D. G., Christopherson, G. T., Dong, X. N., Fyhrie, D. P., andYeni, Y. N. (2004): \u2018The effect of microcomputed tomography scanning and reconstruction voxel size on the accuracy of stereological measurements in human cancellous bone\u2019,Bone,35, pp. 1375\u20131382","journal-title":"Bone"},{"key":"BF02344727_CR19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.3233\/THC-1998-65-606","volume":"6","author":"A. Laib","year":"1998","unstructured":"Laib, A., Hauselmann, H. J., andRuegsegger, P. (1998): \u2018In vivo high resolution 3D-QCT of the human forearm\u2019,Technol. Health Care,6, pp. 329\u2013337","journal-title":"Technol. Health Care"},{"key":"BF02344727_CR20","volume-title":"Basic biomechanics of the musculoskeletal system","author":"M. Lindh","year":"1989","unstructured":"Lindh, M. (1989): \u2018Biomechanics of the lumbar spine\u2019, in Nordin, M., and Frankel, V. H. (Eds). \u2018Basic biomechanics of the musculoskeletal system\u2019 (Lea & Febiger, Philadelphia, London, 1989)"},{"key":"BF02344727_CR21","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.joca.2003.10.009","volume":"12","author":"C. T. Lindsey","year":"2004","unstructured":"Lindsey, C. T., Narasimhan, A., Adolfo, J. M., Jin, H., Steinbach, L. S., Link, T., Ries, M., andMajumdar, S. (2004): \u2018Magnetic resonance evaluation of the interrelationship between articular cartilage and trabecular bone of the osteoarthritic knee\u2019,Osteoarthr. Cartilage,12, pp. 86\u201396","journal-title":"Osteoarthr. Cartilage"},{"key":"BF02344727_CR22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1359\/jbmr.1997.12.1.111","volume":"12","author":"S. Majumdar","year":"1997","unstructured":"Majumdar, S., Genant, H. K., Grampp, S., Newitt, D. C., Truong, V. H., Lin, J. C., andMathur, A. (1997): \u2018Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status:in vivo studies in the distal radius using high resolution magnetic resonance imaging\u2019,J. Bone Miner. Res.,12, pp. 111\u2013118","journal-title":"J. Bone Miner. Res."},{"key":"BF02344727_CR23","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2106\/00004623-199703000-00016","volume":"79","author":"R. W. McCalder","year":"1997","unstructured":"McCalder, R. W., McGeough, J. A., andCourt-brown, C. M., (1997): \u2018Age-related changes in the compressive strength of cancellous bone. The relative importance of changes in density and trabecular architecture\u2019,J. Bone. Joint. Surg. Am.,79-A, pp. 421\u2013427","journal-title":"J. Bone. Joint. Surg. Am."},{"key":"BF02344727_CR24","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S8756-3282(98)00036-2","volume":"22","author":"D. Mitton","year":"1998","unstructured":"Mitton, D., Cendre, E., Roux, J. P., Arlot, M. E., Peix, G., Rumelhart, C., Babot, D., andMeunier, P. J. (1998): \u2018Mechanical properties of ewe vertebral cancellous bone compared with parameters\u2019,Bone,22, pp. 651\u2013658","journal-title":"Bone"},{"key":"BF02344727_CR25","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.jbiomech.2004.06.007","volume":"38","author":"E. Mittra","year":"2005","unstructured":"Mittra, E., Rubin, C., andQin, Y. X. (2005): \u2018Interrelationship of trabecular mechanical and microstructural properties in sheep trabecular bone\u2019,J. Biomech.,38, pp. 1229\u20131237","journal-title":"J. Biomech."},{"key":"BF02344727_CR26","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0021-9290(03)00071-X","volume":"36","author":"E. F. Morgan","year":"2003","unstructured":"Morgan, E. F., Bayraktar, H. H., andKeaveny, T. M. (2003): \u2018Trabecular bone modulus-density relationships depend on anatomic site\u2019,J.Biomech.,36, pp. 897\u2013904","journal-title":"J.Biomech."},{"key":"BF02344727_CR27","volume-title":"Basic biomechanics of the musculoskeletal system","author":"M. Nordin","year":"1989","unstructured":"Nordin, M., andFrankel, V. H. (1989): \u2018Biomechanics of bone\u2019, in Nordin, M., and Frankel, V. H. (Eds): \u2018Basic biomechanics of the musculoskeletal system\u2019 (Lea & Febiger, Philadelphia, London, 1989)."},{"key":"BF02344727_CR28","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0021-9290(97)00052-3","volume":"30","author":"R. M. Pidaparti","year":"1997","unstructured":"Pidaparti, R. M., andTurner, C. H. (1997): \u2018Cancellous bone architecture: advantages of nonorthogonal trabecular alignment under multidirectional joint loading\u2019,J. Biomech.,30, pp. 979\u2013983","journal-title":"J. Biomech."},{"key":"BF02344727_CR29","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0733-8619(05)70112-2","volume":"17","author":"M. H. Pope","year":"1999","unstructured":"Pope, M. H., andDeVocht, J. W. (1999): \u2018The clinical relevance of biomechanics\u2019,Neurol. Clin.,17, pp. 17\u201341","journal-title":"Neurol. Clin."},{"key":"BF02344727_CR30","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/S8756-3282(02)00686-5","volume":"30","author":"J. S. Thomsen","year":"2002","unstructured":"Thomsen, J. S., Ebbesen, E. N., andMoskilde, L. (2002): \u2018Zonedependent changes in human vertebral trabecular bone: Clinical implications\u2019,Bone,30, pp. 664\u2013669","journal-title":"Bone"},{"key":"BF02344727_CR31","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0021-9290(95)80008-5","volume":"28","author":"B. Rietbergen van","year":"1995","unstructured":"van Rietbergen, B., Weinans, H., Huiskes, R., andOdgaard, A. (1995): \u2018A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models\u2019,J. Biomech.,28, pp. 69\u201381","journal-title":"J. Biomech."},{"key":"BF02344727_CR32","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0021-9290(98)00150-X","volume":"32","author":"B. Rietbergen van","year":"1999","unstructured":"van Rietbergen, B., Muller, R., R. Ulrich,Ruegsegger, P., andHuiskes, R. (1999): \u2018Tissue stresses and strain in trabeculae of a canine proximal femur can be quantified from computer reconstructions\u2019,J. Biomech.,32, pp. 443\u2013451","journal-title":"J. Biomech."},{"key":"BF02344727_CR33","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1359\/jbmr.2003.18.10.1781","volume":"18","author":"B. Rietbergen van","year":"2003","unstructured":"van Rietbergen, B., Huiskes, R., Eckstein, F., andRuegsegger, P. (2003): \u2018Trabecular bone tissue strains in the healthy and osteoporotic human femur\u2019,J. Bone Miner. Res.,18, pp. 1781\u20131788","journal-title":"J. Bone Miner. Res."}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02344727.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02344727\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02344727","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T06:09:25Z","timestamp":1586758165000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02344727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["BF02344727"],"URL":"https:\/\/doi.org\/10.1007\/bf02344727","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}