{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:18:38Z","timestamp":1769170718010,"version":"3.49.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Biol. Eng. Comput."],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1007\/bf02351032","type":"journal-article","created":{"date-parts":[[2006,3,16]],"date-time":"2006-03-16T02:06:45Z","timestamp":1142474805000},"page":"589-598","source":"Crossref","is-referenced-by-count":19,"title":["Robust and self-tuning blood flow control during extracorporeal circulation in the presence of system parameter uncertainties"],"prefix":"10.1007","volume":"43","author":[{"given":"B. J. E.","family":"Misgeld","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Werner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hexamer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02351032_CR1","first-page":"117","volume":"2","author":"J. Anbe","year":"1992","unstructured":"Anbe, J., Nakajima, H., Ogura, Y., Ozeki, M., Mitsuishi, T., Akasaka, T., andTobi, T. (1992a): \u2018Development of a computerregulated extracorporeal circulation system\u2019,Artif. Organs Today,2, pp. 117\u2013125","journal-title":"Artif. Organs Today"},{"key":"BF02351032_CR2","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1525-1594.1992.tb00338.x","volume":"16","author":"J. Anbe","year":"1992","unstructured":"Anbe, J., Tobi, T., Nakajima, H., Akasaka, T. and OKINAGA, K. (1992b): \u2018Microcomputer-based automatic regulation of extracorporeal circulation: a trial for the application of fuzzy inference\u2019,Artif. Organs,16, pp. 532\u2013538","journal-title":"Artif. Organs"},{"key":"BF02351032_CR3","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0020-7101(88)90006-2","volume":"22","author":"G. Avanzolini","year":"1988","unstructured":"Avanzolini, G., Barbini, P., Capello, A., andCevenini, G. (1988): \u2018Cades simulation of the closed-loop cardiovascular system\u2019,Int. J. Biomed. Comput.,22, pp. 39\u201349","journal-title":"Int. J. Biomed. Comput."},{"key":"BF02351032_CR4","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/BF02441895","volume":"18","author":"A. P. Avolio","year":"1980","unstructured":"Avolio, A. P. (1980): \u2018Multi-branched model of the human arterial system\u2019,Med. Biol. Eng. Comput.,18, pp. 709\u2013718","journal-title":"Med. Biol. Eng. Comput."},{"key":"BF02351032_CR5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/026765919901400502","volume":"14","author":"R. Bauernschmitt","year":"1999","unstructured":"Bauernschmitt, R., Naujokat, E., Mehmanesh, H., Schulz, S., Vahl, C. F., Hagl, S., andLange, R. (1999): \u2018Mathematical modelling of extracorporeal circulation: simulation of different perfusion regimens\u2019Perfusion,14, pp. 321\u2013330","journal-title":"Perfusion"},{"key":"BF02351032_CR6","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/scj.4690231107","volume":"23","author":"T. Beppu","year":"1992","unstructured":"Beppu, T., Imai, Y., andFukui, Y. (1992): \u2018Computer-controlled cardiopulmonary bypass system\u2019,Syst. Comput. Jpn.,23, pp. 74\u201384","journal-title":"Syst. Comput. Jpn."},{"key":"BF02351032_CR7","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0022-5223(95)70273-3","volume":"109","author":"T. Beppu","year":"1995","unstructured":"Beppu, T., Imai, Y., andFukui, Y. (1995): \u2018A computerized control system for cardiopulmonary bypass\u2019,J. Thorac. Cardiovasc. Surg.,109, pp. 428\u2013438","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"BF02351032_CR8","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1177\/039139889702000608","volume":"20","author":"F. Boschetti","year":"1997","unstructured":"Boschetti, F., Montevecchi, F. M., andFumero, R. (1997): \u2018Virtual extracorporeal circulation process\u2019,Int. J. Artif. Organs,20, pp. 341\u2013351","journal-title":"Int. J. Artif. Organs"},{"key":"BF02351032_CR9","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0005-1098(87)90087-2","volume":"23","author":"D. W. Clarke","year":"1987","unstructured":"Clarke, D. W., Mohtadi, C., andTuffs, P. S. (1987): \u2018Generalized predictive control-Part I\/II\u2019,Automatica,23, pp. 137\u2013140","journal-title":"Automatica"},{"key":"BF02351032_CR10","unstructured":"De Pater, L. (1966): \u2018An electrical analogue of the human circulatory system\u2019,PhD thesis, University of Groningen"},{"key":"BF02351032_CR11","first-page":"483","volume":"37","author":"O. Frank","year":"1899","unstructured":"Frank, O. (1899): \u2018Die Grundform des arteriellen Pulses\u2019,Z. Biol.,37, pp. 483\u2013526","journal-title":"Z. Biol."},{"key":"BF02351032_CR12","first-page":"133","volume":"28","author":"Y. Fukui","year":"1982","unstructured":"Fukui, Y., Tsuchiya, K., andImai, Y. (1982): \u2018Computer controlled extracorporeal circulation (ECC) with pulsatile perfusion for an infant\u2019,Trans. Am. Soc. Artifn. Intern. Organs,28, pp. 133\u2013137","journal-title":"Trans. Am. Soc. Artifn. Intern. Organs"},{"key":"BF02351032_CR13","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1046\/j.1525-1594.2001.025005358.x","volume":"25","author":"C. G\u00f6bel","year":"2001","unstructured":"G\u00f6bel, C., Arvand, A., Eilers, R., Marselle, O., Bals, C., Meyns, B., Flameng, W., Rau, G., andReul, H. (2001): \u2018Development of the MEDOS\/HIA DeltaStream extracorporeal rotary blood pump\u2019,Artif. Organs,25, pp. 358\u2013365","journal-title":"Artif. Organs"},{"key":"BF02351032_CR14","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1177\/026765919400900306","volume":"9","author":"T. Gourlay","year":"1994","unstructured":"Gourlay, T., andTaylor, K.M. (1994): \u2018Pulsatile flow and membrane oxygenators\u2019,Perfusion,9, pp. 189\u2013196","journal-title":"Perfusion"},{"key":"BF02351032_CR15","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1161\/01.CIR.63.6.1305","volume":"63","author":"W. Gundel","year":"1981","unstructured":"Gundel, W., Cherry, G., Rajagopalan, B., Tan, L.-B., Lee, G., andSchultz, D. (1981): \u2018Aortic input impedance in man: acute response to vasodilator drugs\u2019,Circulation,63, pp. 1305\u20131314","journal-title":"Circulation"},{"key":"BF02351032_CR16","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/00000542-199508000-00017","volume":"83","author":"D. A. Hettrick","year":"1995","unstructured":"Hettrick, D. A., Pagel, P.S., andWarltier, D. C. (1995): \u2018Differential effects of isoflurane and halothane on aortic input impedance quantified using a three-element Windkessel model\u2019,Anesthesiology,83, pp. 361\u2013373","journal-title":"Anesthesiology"},{"key":"BF02351032_CR17","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1115\/1.3662552","volume":"82","author":"R. E. Kalman","year":"1960","unstructured":"Kalman, R. E. (1960): \u2018A new approach to linear filtering and prediction problems\u2019,Trans. ASME J. Basic Eng.,82, pp. 35\u201345","journal-title":"Trans. ASME J. Basic Eng."},{"key":"BF02351032_CR18","doi-asserted-by":"crossref","DOI":"10.1201\/b13407","volume-title":"Techniques in extracorporeal circulation","author":"P. H. Kay","year":"2004","unstructured":"Kay, P. H., andMunsch, C. M. (2004): \u2018Techniques in extracorporeal circulation\u2019, (Arnold, London, U.K., 2004)"},{"key":"BF02351032_CR19","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1161\/01.RES.62.5.884","volume":"62","author":"T. W. Latson","year":"1988","unstructured":"Latson, T. W., Hunter, W. C., Katoh, N., andSagawa, K. (1988): \u2018Effect of nitroglycerin on aortic impedance, diameter, and pulsewave velocity\u2019,Circ. Res.,62, pp. 884\u2013890","journal-title":"Circ. Res."},{"key":"BF02351032_CR20","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/00000542-199602000-00015","volume":"84","author":"D. Lowe","year":"1996","unstructured":"Lowe, D., Hettrick, D. A., Pagel, P. S., andWarltier, D. C. (1996): \u2018Propofol alters left ventricular afterload as evaluated by aortic input impedance in dogs\u2019,Anesthesiology,84, pp. 368\u2013376","journal-title":"Anesthesiology"},{"key":"BF02351032_CR21","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-09725-0","volume-title":"Regelungstechnik 2","author":"J. Lunze","year":"2002","unstructured":"Lunze, J. (2002): \u2018Regelungstechnik 2\u2019, (Springer-Verlag, Berlin, Germany, 2002)"},{"key":"BF02351032_CR22","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1109\/TAC.1985.1103950","volume":"30","author":"B. McInnis","year":"1985","unstructured":"McInnis, B., Guo, Z-W., Lu, P., andWang, J.-C. (1985): \u2018Adaptive control of left ventricular bypass assist devices\u2019,IEEE Trans. Automat. Contr.,30, pp. 322\u2013329","journal-title":"IEEE Trans. Automat. Contr."},{"key":"BF02351032_CR23","unstructured":"Nagel, M. (2004): \u2018Aufbau eines Versuchsstandes zur Simulation des menschlichen Kreislaufs unter den Bedingungen der extrakorporalen membranoxygenation (ECMO)\u2019.Master Thesis, Dortmund University"},{"key":"BF02351032_CR24","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-04323-3","volume-title":"Nonlinear system identification","author":"O. Nelles","year":"2001","unstructured":"Nelles, O. (2001): \u2018Nonlinear system identification\u2019, (Springer-Verlag, Berlin, Germany, 2001)"},{"key":"BF02351032_CR25","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1525-1594.1995.tb02410.x","volume":"19","author":"H. Nishida","year":"1995","unstructured":"Nishida, H., Beppu, T., Nakajima, M., Nishinaka, T., Nakatani, H., Ihashi, K., Katsumata, T., Kitamura, M., Aomi, S., Endo, M.,et al. (1995): \u2018Development of an autoflow cruise control system for a centrifugal pump\u2019,Artif. Organs,19, pp. 713\u2013718","journal-title":"Artif. Organs"},{"key":"BF02351032_CR26","volume-title":"Discrete \u2014time control systems","author":"K. Ogata","year":"1987","unstructured":"Ogata, K. (1987): \u2018Discrete \u2014time control systems\u2019 (Prentice \u2014 Hall, New Jersey, USA, 1987)"},{"key":"BF02351032_CR27","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/j.1525-1594.2003.47197.x","volume":"28","author":"G. Pennati","year":"2004","unstructured":"Pennati, G., Fiore, G. B., Lagan\u00e1, K., andFumero, R. (2004): \u2018Mathematical modelling of fluid dynamics in pulsatile cardiopulmonary bypass\u2019,Artif. Organs,28, pp. 196\u2013209","journal-title":"Artif. Organs"},{"key":"BF02351032_CR28","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1172\/JCI109505","volume":"64","author":"C. J. Pepine","year":"1979","unstructured":"Pepine, C. J., Nichols, W. W., Curry, R. C., andConti, C. R. (1979): \u2018Aortic input impedance during nitroprusside infusion. A reconsideration of afterload reduction and beneficial action\u2019,J. Clin. Invest.,64, pp. 643\u2013654","journal-title":"J. Clin. Invest."},{"key":"BF02351032_CR29","first-page":"120","volume":"2","author":"H. Reul","year":"1975","unstructured":"Reul, H., Minamitani, H., andRunge, J (1975): \u2018A hydraulic analog of the systemic and pulmonary circulation for testing artificial hearts\u2019,Proc. ESAO,2, pp. 120\u2013127","journal-title":"Proc. ESAO"},{"key":"BF02351032_CR30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1109\/TBME.1972.324103","volume":"19","author":"V. C. Rideout","year":"1972","unstructured":"Rideout, V. C. (1972): \u2018Cardiovascular system simulation in biomedical engineering education\u2019,IEEE Trans. Biomed. Eng.,19, pp. 101\u2013107","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"BF02351032_CR31","first-page":"21","volume":"40","author":"A. Schwarzhaupt","year":"1998","unstructured":"Schwarzhaupt, A., andKiencke, U. (1998): \u2018Entwicklungen in der Automatisierung von Herz-Lungen-Maschinen\u2019,Automatisierung-stechnische Praxis,40, pp. 21\u201324","journal-title":"Automatisierung-stechnische Praxis"},{"key":"BF02351032_CR32","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1515\/bmte.1998.43.10.275","volume":"43","author":"A. Schwarzhaupt","year":"1998","unstructured":"Schwarzhaupt, A., Qaqunda, B., andKiencke, U. (1998): \u2018Entwurf eines pr\u00e4diktiven MIMO-Reglers f\u00fcr Herz-Lungen-Maschinen auf der Grundlage eines Modells der extrakorporalen Zirkulation\u2019,Biomed. Tech.,43, pp. 336\u2013337","journal-title":"Biomed. Tech."},{"key":"BF02351032_CR33","first-page":"252","volume":"36","author":"H. Schima","year":"1990","unstructured":"Schima, H., Honigschnabel, J., Trubel, W., andThoma, H. (1990): \u2018Computer simulation of the circulatory system during support with a rotary blood pump\u2019,ASAIO Trans.,36, pp. 252\u2013254","journal-title":"ASAIO Trans."},{"key":"BF02351032_CR34","first-page":"48","volume":"3","author":"P. Segers","year":"1998","unstructured":"Segers, P., Dubois, F., De Wachter, D., andVerdonck, P. (1998): \u2018Role and Relevancy of a Cardiovascular Simulator\u2019,CVE.,3, pp. 48\u201356","journal-title":"CVE."},{"key":"BF02351032_CR35","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1525-1594.1991.tb00769.x","volume":"15","author":"T. Shimooka","year":"1991","unstructured":"Shimooka, T., Mitamura, Y., andYuhta, T. (1991): \u2018Investigation of parameter estimator and adaptive controller for assist pump by computer simulation\u2019,Artif. Organs,15, pp.119\u2013128","journal-title":"Artif. Organs"},{"key":"BF02351032_CR36","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0021-9290(68)90029-8","volume":"1","author":"M. F. Snyder","year":"1968","unstructured":"Snyder, M. F., Rideout, V. C., andHillestad, R. J. (1968): \u2018Computer modelling of the human systemic arterial tree\u2019,J. Biomech.,1, pp. 341\u2013353","journal-title":"J. Biomech."},{"key":"BF02351032_CR37","first-page":"918","volume-title":"Progress in artificial organs","author":"K. Soejima","year":"1983","unstructured":"Soejima, K., Nagase, Y., Ishihara, K., Takanashi, Y., Imai, Y., Tsuchiya, K., andFukui, Y. (1983): \u2018Computer-assisted automatic cardiopulmonary bypass system for infants\u2019, inAtsumi, K., Maekawa, M., andOta, K. (Eds). \u2018Progress in artificial organs\u2019 (ISAO Press, Cleveland, OH, USA, 1983), pp. 918\u2013922"},{"key":"BF02351032_CR38","unstructured":"Womersley, J. R. (1957): \u2018An elastic tube theory of pulse transmission and oscillatory flow in mammalian arteries\u2019.WADC Technical Report, pp. 56\u2013614"},{"key":"BF02351032_CR39","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1177\/026765918800300402","volume":"3","author":"G. Wright","year":"1988","unstructured":"Wright, G. (1988): \u2018The hydraulic power outputs of pulsatile and nonpulsatile cardiopulmonary bypass pumps\u2019,Perfusion,3, pp. 251\u2013262","journal-title":"Perfusion"},{"key":"BF02351032_CR40","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1109\/9.679017","volume":"43","author":"Y. Yih-Choung","year":"1998","unstructured":"Yih-Choung, Y., Boston, J. R., Simaan, M. A., andAntaki, J. F. (1998): \u2018Estimation of systemic vascular bed parameters for artificial heart control\u2019,IEEE Trans. Automat. Control. 43, pp. 765\u2013778","journal-title":"IEEE Trans. Automat. Control."},{"key":"BF02351032_CR41","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1109\/TAC.1981.1102603","volume":"26","author":"G. Zames","year":"1981","unstructured":"Zames, G. (1981): \u2018Feedback and optimum sensitivity: Model reference transformations, multiplicative seminorms, and approximate inverses\u2019,IEEE Trans. Automat. Control,26, pp. 301\u2013320","journal-title":"IEEE Trans. Automat. Control"},{"key":"BF02351032_CR42","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1109\/TAC.1983.1103275","volume":"28","author":"G. Zames","year":"1983","unstructured":"Zames, G., andFrancis, B. (1983): \u2018Feedback, minimax sensitivity, and optimum robustness\u2019,IEEE Trans. Autom. Control,28, pp. 585\u2013601","journal-title":"IEEE Trans. Autom. Control"}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02351032.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02351032\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02351032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,13]],"date-time":"2020-04-13T06:38:24Z","timestamp":1586759904000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02351032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["BF02351032"],"URL":"https:\/\/doi.org\/10.1007\/bf02351032","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}