{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:37:47Z","timestamp":1762375067731},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med. Biol. Eng. Comput."],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1007\/bf02351043","type":"journal-article","created":{"date-parts":[[2006,3,16]],"date-time":"2006-03-16T02:06:45Z","timestamp":1142474805000},"page":"678-685","source":"Crossref","is-referenced-by-count":8,"title":["Parametric image of myocardial blood flow generated from dynamic H2 15O PET using factor analysis and cluster analysis"],"prefix":"10.1007","volume":"43","author":[{"given":"J. S.","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Y.","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J.","family":"Cheon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. -K.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. S.","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. -K.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02351043_CR1","first-page":"782","volume":"42","author":"J. Y. Ahn","year":"2001","unstructured":"Ahn, J. Y., Lee, D. S., Lee, J. S., Kim, S. K., Cheon, G. J., Yeo, J. S., Shin, S. A., Chung, J. K., andLee, M. C. (2001): \u2018Quantification of regional myocardial blood flow using dynamic H2 15O PET and factor analysis\u2019.J. Nucl. Med.,42, pp. 782\u2013787","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR2","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1161\/01.CIR.83.3.875","volume":"83","author":"L. I. Araujo","year":"1991","unstructured":"Araujo, L. I., Lammertsma, A. A., Rhodes, C. G., McFalls, E. O., Iida, H., Rechavia, E., Galassi, A., De Silva, R., Jones, T., andMaseri, A. (1991): \u2018Noninvasive quantification of regional myocardial blood flow in coronary artery disease with oxygen-15-labeled carbon dioxide inhalation and positron emission tomography\u2019,Circulation,83, pp. 875\u2013885","journal-title":"Circulation"},{"key":"BF02351043_CR3","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1088\/0031-9155\/25\/2\/008","volume":"25","author":"D. C. Barber","year":"1980","unstructured":"Barber, D. C. (1980): \u2018The use of principal components in the quantitative analysis of gamma camera dynamic studies\u2019,Phys. Med. Biol.,25, pp. 283\u2013292","journal-title":"Phys. Med. Biol."},{"key":"BF02351043_CR4","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1161\/01.CIR.70.4.724","volume":"70","author":"S. R. Bergmann","year":"1984","unstructured":"Bergmann, S. R., Fox, K. A., Rand, A. L., McElvany, K. D., Welch, M. J., Markham, J., andSobel, B. E. (1984): \u2018Quantification of regional myocardial blood flow in vivo with H2 15O\u2019,Circulation,70, pp. 724\u2013733","journal-title":"Circulation"},{"key":"BF02351043_CR5","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1161\/01.STR.13.6.842","volume":"13","author":"D. J. Boarini","year":"1982","unstructured":"Boarini, D. J., Kassell, N. F., Olin, J. J., andSprowell, J. A. (1982): \u2018The effect of intravenous dipyridamole on the cerebral and systemic circulations of the dog\u2019,Stroke,13, pp. 842\u2013847","journal-title":"Stroke"},{"key":"BF02351043_CR6","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1161\/01.CIR.87.2.512","volume":"87","author":"A. Bol","year":"1993","unstructured":"Bol, A., Melin, J. A., Vanoverschelde, J. L., Baudhuin, T., Vogelaers, D., De Pauw, M., Michel, C., Luxen, A., Labar, D., Cogneau, M. et al. (1993): \u2018Direct comparison of [13N]ammonia and [15O]water estimates of perfusion with quantification of regional myocardial blood flow by microspheres\u2019,Circulation,87, pp. 512\u2013525","journal-title":"Circulation"},{"key":"BF02351043_CR7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1109\/42.700735","volume":"17","author":"K. Chen","year":"1998","unstructured":"Chen, K., Lawson, M., Reiman, E., Cooper, A., Feng, D., Huang, S. C., Bandy, D., Ho, D., Yun, L. S., andPalant, A. (1998): \u2018Generalized linear least squares method for fast generation of myocardial blood flow parametric images with N-13 ammonia PET\u2019,IEEE Trans. Med. Imaging,17, pp. 236\u2013243","journal-title":"IEEE Trans. Med. Imaging"},{"key":"BF02351043_CR8","first-page":"488","volume":"34","author":"Y. Choi","year":"1993","unstructured":"Choi, Y., Huang, S. C., Hawkins, R. A., Kuhle, W. G., Dahlbom, M., Hoh, C. K., Czernin, J., Phelps, M. E., andSchelbert, H. R. (1993): \u2018A simplified method for quantification of myocardial blood flow using nitrogen-13-ammonia and dynamic PET\u2019,J. Nucl. Med.,34, pp. 488\u2013497","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR9","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1109\/TNS.1982.4332188","volume":"29","author":"R. Di Paola","year":"1982","unstructured":"Di Paola, R., Bazin, J. P., Aubry, F., Aurengo, A., Cavailloles, F., Herry, J. Y., andKahn, E. (1982): \u2018Handling of dynamic sequences in nuclear medicine\u2019,IEEE Trans. Nucl. Sci.,29, pp. 1310\u20131321","journal-title":"IEEE Trans. Nucl. Sci."},{"key":"BF02351043_CR10","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1109\/42.232247","volume":"12","author":"D. Feng","year":"1993","unstructured":"Feng, D., Wang, Z., andHuang, S.-C. (1993): \u2018A study on statistically reliable and computationally efficient algorithms for generating local cerebral blood flow parametric images with positron emission tomography\u2019,IEEE Trans. Med. Imaging.,12, pp. 182\u2013188","journal-title":"IEEE Trans. Med. Imaging."},{"key":"BF02351043_CR11","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1109\/42.511754","volume":"15","author":"D. Feng","year":"1996","unstructured":"Feng, D., Huang, S.-C., Wang, Z., andHo, D. (1996): \u2018An unbiased parametric imaging algorithm for nonuniformly sampled biomedical system parameter estimation\u2019,IEEE Trans. Med. Imaging,15, pp. 512\u2013518","journal-title":"IEEE Trans. Med. Imaging"},{"key":"BF02351043_CR12","first-page":"862","volume":"34","author":"H. Gewirtz","year":"1993","unstructured":"Gewirtz, H. (1993): \u2018Parametric images for quantitative measurements of regional myocardial blood flow in humans: a step in the right direction\u2019,J. Nucl. Med.,34, pp. 862\u2013864","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR13","first-page":"1696","volume":"29","author":"F. Hermansen","year":"1998","unstructured":"Hermansen, F., Ashburner, J., Spinks, T. J., Kooner, J. S., Camici, P. G., andLammertsma, A. A. (1998): \u2018Generation of myocardial factor images directly from the dynamic oxygen-15-water scan without use of an oxygen-15-carbon monoxide blood-pool scan\u2019,J. Nucl. Med.,29, pp. 1696\u20131702","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR14","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0895-7177(88)90605-X","volume":"11","author":"P. Herrero","year":"1988","unstructured":"Herrero, P., Markham, J., Myears, D. W., Weiheimer, C. J., andBergmann, S. R. (1988): \u2018Measurement of myocardial blood flow with positron emission tomography: correction for count spillover and partial volume effects\u2019,Math. Comput. Model.,11, pp. 807\u2013812","journal-title":"Math. Comput. Model."},{"key":"BF02351043_CR15","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0033-0620(77)80005-4","volume":"20","author":"M. A. Heymann","year":"1977","unstructured":"Heymann, M. A., Payne, B. D., Hoffman, J. I., andRudolph, A. M. (1977): \u2018Blood flow measurements with radionuclide-labeled particles\u2019,Prog. Cardiovasc. Dis.,20, pp. 55\u201379","journal-title":"Prog. Cardiovasc. Dis."},{"key":"BF02351043_CR16","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1161\/01.CIR.78.1.104","volume":"78","author":"H. Iida","year":"1988","unstructured":"Iida, H., Kanno, I., Takahashi, A., Miura, S., Murakami M., Takahashi, K., Ono, Y., Shishido, F., Inugami, A., andTomura, N. (1988): \u2018Measurement of absolute myocardial blood flow with H2 15O and dynamic positron-emission tomography. Strategy for quantification in relation to the partial-volume effect\u2019,Circulation,78, pp. 104\u2013115","journal-title":"Circulation"},{"key":"BF02351043_CR17","first-page":"2169","volume":"32","author":"H. Iida","year":"1991","unstructured":"Iida, H., Rhodes, C. G., De Silva, R., Yamamoto, Y., Araujo, L. I., Maseri, A., andJones, T. (1991): \u2018Myocardial tissue fraction-correction for partial volume effects and measure of tissue viability\u2019,J. Nucl. Med.,32, pp. 2169\u20132175","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR18","first-page":"1737","volume":"41","author":"H. Iida","year":"2000","unstructured":"Iida, H., Tamura, Y., Kitamura, K., Bloomfield, P. M., Eberl, S., andOno, Y. (2000): \u2018Histochemical correlates of15O-water-perfusable tissue fraction in experimental canine studies of old myocardial infarction\u2019,J. Nucl. Med.,41, pp. 1737\u20131745","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR19","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3171\/jns.1983.58.1.0069","volume":"58","author":"N. F. Kassell","year":"1983","unstructured":"Kassell, N. F., Boarini, D. J., Olin, J. J., andSprowell, J. A. (1983): \u2018Cerebral and systemic circulatory effects of arterial hypotension induced by adenosine\u2019,J. Neurosurg.,58, pp. 69\u201376","journal-title":"J. Neurosurg."},{"key":"BF02351043_CR20","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1006\/nimg.1999.0430","volume":"9","author":"Y. Kimura","year":"1999","unstructured":"Kimura, Y., Hsu, H., Toyama, H., Senda, M. andAlpert, N. M. (1999): \u2018Improved signal-to-noise ratio in parametric images by cluster analysis\u2019,Neuroimage,9, pp. 554\u2013561","journal-title":"Neuroimage"},{"key":"BF02351043_CR21","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1088\/0031-9155\/47\/3\/307","volume":"47","author":"Y. Kimura","year":"2002","unstructured":"Kimura, Y., Senda, M., andAlpert, N. M. (2002): \u2018Fast formation of statistically reliable FDG parametric images based on clustering and principal components\u2019,Phys. Med. Biol.,47, pp. 455\u2013468","journal-title":"Phys. Med. Biol."},{"key":"BF02351043_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1088\/0143-0815\/13\/1\/001","volume":"13","author":"A. A. Lammertsma","year":"1992","unstructured":"Lammertsma, A. A., De Silva, R., Araujo, L. I., andJones, T. (1992): \u2018Measurement of regional myocardial blood flow using C15O2 and positron emission tomography: comparison of tracer models\u2019,Clin. Phys. Physiol. Meas.,13, pp. 1\u201320","journal-title":"Clin. Phys. Physiol. Meas."},{"key":"BF02351043_CR23","unstructured":"Lee, B. I., Lee, J. S., Lee, D. S., Kang, W. J., Lee, J. J., Kim, S. J., Choi, S. J., Chung, J.-K. andLee, M. C. (2005): \u2018Assessment of the feasibility of ensemble ICA for the quantification of myocardial blood flow using dynamic H2 15O PET\u2019,J. Nucl. Med.,5, in press"},{"key":"BF02351043_CR24","unstructured":"Lee, J. S., Ahn, J. Y., Lee, D. S., Seo, K., andPark, K. S. (2000): \u2018Application of factor and cluster analysis for the parametric image of myocardial blood flow using H2 15O and dynamic PET\u2019.Proc. IEEE Nucl. Sci. Symp. Med. Imag. Conf."},{"key":"BF02351043_CR25","first-page":"938","volume":"42","author":"J. S. Lee","year":"2001","unstructured":"Lee, J. S., Lee, D. S., Ahn, J. Y., Cheon, G. J., Kim, S. K., Yeo, J. S., Seo, K., Park, K. S., Chung, J. K., andLee, M. C. (2001a): \u2018Blind separation of cardiac components and extraction of input function from H2 15O dynamic myocardial PET using independent component analysis\u2019,J. Nucl. Med.,42, pp. 938\u2013943","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR26","unstructured":"Lee, J. S., Lee, D. D., Choi, S., Park, K. S., andLee, D. S. (2001b): \u2018Non-negative matrix factorization of dynamic images in nuclear medicine\u2019.Proc. IEEE Nucl. Sci. Symp. Med. Imag. Conf."},{"key":"BF02351043_CR27","first-page":"59","volume":"5","author":"J. S. Lee","year":"2001","unstructured":"Lee, J. S., Ahn, J. Y., Lee, D. S., Iida, H., Kim, K. M., Yeo, J. S., Cheon, G. J., Kim, S.-K., Park, K. S., Chung, J.-K., andLee, M. C. (2001c): \u2018Generation of MBF parametric image from H2 15O dynamic myocardial PET using linear least squares method\u2019,J. Nucl. Med.,5, p. 59P (Abstract)","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR28","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780192619945.001.0001","volume-title":"Physiological measurements with radionuclides in clinical practice","author":"A. M. Peters","year":"1998","unstructured":"Peters, A. M., andMyers, M. J. (1998): \u2018Physiological measurements with radionuclides in clinical practice\u2019 (Oxford Medical Publications, Oxford, 1998)"},{"key":"BF02351043_CR29","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1109\/42.996340","volume":"21","author":"A. Sitek","year":"2002","unstructured":"Sitek, A., Gullberg, G. T., andHuesman, R. H. (2002): \u2018Correction for ambiguous solutions in factor analysis using a penalized least squares objective\u2019,IEEE Trans. Med. Imaging,21, pp. 216\u2013225","journal-title":"IEEE Trans. Med. Imaging"},{"key":"BF02351043_CR30","first-page":"2087","volume":"36","author":"H. M. Wu","year":"1995","unstructured":"Wu, H. M., Hoh, C. K., Buxton, D. B., Kuhle, W. G., Schelbert, H. R., Choi, Y., Hawkins, R. A., Phelps, M. E., andHuang, S. C. (1995a): \u2018Quantification of myocardial blood flow using dynamic nitrogen-13-ammonia PET studies and factor analysis of dynamic structures\u2019,J. Nucl. Med.,36, pp. 2087\u20132093","journal-title":"J. Nucl. Med."},{"key":"BF02351043_CR31","first-page":"1714","volume":"36","author":"H. M. Wu","year":"1995","unstructured":"Wu, H. M., Hoh, C. K., Choi, Y., Schelbert, H. R., Hawkins, R. A., Phelps, M. E., andHuang, S. C. (1995b): \u2018Factor analysis for extraction of blood time-activity curves in dynamic FDG-PET studies\u2019,J. Nucl. Med.,36, pp. 1714\u20131722","journal-title":"J. Nucl. Med."}],"container-title":["Medical and Biological Engineering and Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02351043.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/BF02351043\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02351043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02351043.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T10:16:52Z","timestamp":1706955412000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/BF02351043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["BF02351043"],"URL":"https:\/\/doi.org\/10.1007\/bf02351043","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}