{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T15:45:18Z","timestamp":1772898318386,"version":"3.50.1"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"2-3","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Chemical Neuropathology"],"published-print":{"date-parts":[[1998,6]]},"DOI":"10.1007\/bf02815080","type":"journal-article","created":{"date-parts":[[2008,2,2]],"date-time":"2008-02-02T10:47:37Z","timestamp":1201949257000},"page":"197-218","source":"Crossref","is-referenced-by-count":26,"title":["Expression and regulation of complement C1q by human THP-1-derived macrophages"],"prefix":"10.1007","volume":"34","author":[{"given":"Douglas G.","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"BF02815080_CR1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000213842","volume":"43","author":"P. S. Aisen","year":"1997","unstructured":"Aisen, P. S. (1997) Inflammation and Alzheimer\u2019s disease: mechanisms and therapeutic strateties.Gerontology 43, 143\u2013149.","journal-title":"Gerontology"},{"key":"BF02815080_CR2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1006\/exnr.1996.0043","volume":"138","author":"A. Afagh","year":"1996","unstructured":"Afagh A., Cummings B. J., Cribbs D. H., Cotman C. W., and Tenner A. J. (1996) Localization and cell association of C1q in Alzheimer\u2019s disease brain.Exp. Neurol. 138, 22\u201332.","journal-title":"Exp. Neurol."},{"key":"BF02815080_CR3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1042\/bj2160385","volume":"216","author":"J. C. Bensa","year":"1983","unstructured":"Bensa J. C., Reboul A., and Colomb M. G. (1983) Biosynthesis in vitro of complement subcomponents C1q, C1s and C1 inhibitor by resting and stimulated human monocytes.Biochem. J. 216, 385\u2013392.","journal-title":"Biochem. J."},{"key":"BF02815080_CR4","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0169-328X(93)90097-9","volume":"18","author":"L. Brachova","year":"1993","unstructured":"Brachova L., Lue L. F., Schultz J., el Rashidy T., and Rogers J. (1993) Association cortex, cerebellum, and serum concentrations of C1q and factor B in Alzheimer\u2019s disease.Mol. Brain Res. 18, 329\u2013334.","journal-title":"Mol. Brain Res."},{"key":"BF02815080_CR5","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/0197-4580(95)00049-K","volume":"16","author":"J. C. Breitner","year":"1995","unstructured":"Breitner J. C., Welsh K. A., Helms M. J., Gaskell P. C., Gau B. A., Roses A. D., et al. (1995) Delayed onset of Alzheimer\u2019s disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.Neurobiol. Aging 16, 523\u2013530.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR6","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/(SICI)1097-4644(19960201)60:2<235::AID-JCB8>3.0.CO;2-Y","volume":"60","author":"R. Chakrabarti","year":"1996","unstructured":"Chakrabarti R. and Erickson K. L. (1996) Tyrosine kinase but not phospholipid\/Ca2+ signaling pathway is involved in interferon-gamma stimulation of Ia expression in macrophages.J. Cell. Biochem. 60, 235\u2013245.","journal-title":"J. Cell. Biochem."},{"key":"BF02815080_CR7","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1002\/jlb.55.6.778","volume":"55","author":"N. S. Chang","year":"1994","unstructured":"Chang N. S., Intrieri C., Mattison J., and Armand G. (1994) Synthetic polysulfated hyaluronic acid is a potent inhibitor for tumor necrosis factor production.J. Leukocyte Biol. 55, 778\u2013784.","journal-title":"J. Leukocyte Biol."},{"key":"BF02815080_CR8","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/0197-4580(96)00103-0","volume":"17","author":"S. Chen","year":"1996","unstructured":"Chen S., Frederickson R. C. A., and Brunden K. R. (1996) Neuroglial-mediated immunoflammatory responses in Alzheimer\u2019s Disease: Complement activation and therapeutic approaches.Neurobiol. Aging 17, 781\u2013787.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/bj2640021","volume":"264","author":"M. D. Chiara","year":"1989","unstructured":"Chiara M. D., Bedoya F., and Sobrino F. (1989) Cyclosporin A inhibits phorobol esterinduced activation of superoxide production in resident mouse peritoneal macrophages.Biochem. J. 264, 21\u201326.","journal-title":"Biochem. J."},{"key":"BF02815080_CR10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s002329900093","volume":"152","author":"T. E. DeCoursey","year":"1996","unstructured":"DeCoursey T. E., Kim S. Y., Silver M. R., and Quandt F. N. (1996) Ion channel expression in PMA-differentiated human THP-1 macrophages.J. Membr. Biol. 152, 141\u2013157.","journal-title":"J. Membr. Biol."},{"key":"BF02815080_CR11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/BF02890024","volume":"56","author":"P. Eikelenboom","year":"1989","unstructured":"Eikelenboom P., Hack C. E., Rozemuller J. M., and Stam F. C. (1989) Complement activation in amyloid plaques in Alzheimer\u2019s dementia.Virchows Archiv. B 56, 259\u2013262.","journal-title":"Virchows Archiv. B"},{"key":"BF02815080_CR12","first-page":"141","volume":"16","author":"M. Fulop","year":"1993","unstructured":"Fulop M., Webber T., and Manchee R. (1993) Activation of the complement system byFrancisella tularensis lipopolysaccharide.New Microbiol. 16, 141\u2013147.","journal-title":"New Microbiol."},{"key":"BF02815080_CR13","doi-asserted-by":"crossref","first-page":"4726","DOI":"10.4049\/jimmunol.154.9.4726","volume":"154","author":"P. Gasque","year":"1995","unstructured":"Gasque P., Fontaine M., and Morgan B. P. (1995) Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines.J. Immunol. 154, 4726\u20134733.","journal-title":"J. Immunol."},{"key":"BF02815080_CR14","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1161\/01.ATV.14.5.798","volume":"14","author":"Y-J. Geng","year":"1994","unstructured":"Geng Y-J., Kodama T., and Hansson G. K. (1994) Differential expression of scavenger receptor isoforms during monocyte-macrophage differentiation and foam cell formation.Arteriosclerosis Thromb. 14, 798\u2013806.","journal-title":"Arteriosclerosis Thromb."},{"key":"BF02815080_CR15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0167-4889(94)90175-9","volume":"1222","author":"S. P. Green","year":"1994","unstructured":"Green S. P. and Philips W. A. (1994) Activation of the macrophage respiratory burst by phorbol myristate acetate:evidence for both tyrosine-kinase-dependent and independent pathways.Biochim. Biophys. Acta 1222, 241\u2013248.","journal-title":"Biochim. Biophys. Acta"},{"key":"BF02815080_CR16","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0304-3940(96)13040-8","volume":"216","author":"S. Haga","year":"1996","unstructured":"Haga S., Aizawa T, Ishii T., and Ikeda K. (1996) Complement gene expression in mouse microglia and astrocytes in culture\u2014Comparisons with mouse peritoneal macrophages.Neurosci. Lett. 216, 191\u2013194.","journal-title":"Neurosci. Lett."},{"key":"BF02815080_CR17","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.4049\/jimmunol.149.11.3689","volume":"149","author":"P. S. Hicks","year":"1992","unstructured":"Hicks P. S., Saunero-Nava L., Du Clos T. W., and Mold C. (1992) Serum amyloid P component binds to histones and activates the classical complement pathway.J. Immunol. 149, 3689\u20133694.","journal-title":"J. Immunol."},{"key":"BF02815080_CR18","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1042\/bj2570477","volume":"257","author":"R. Hoekzema","year":"1989","unstructured":"Hoekzema R., Brouwer M. C., de Graeff-Meeder E. R., van Helden H. P., and Hack C. E. (1989) Biosynthesis of normal and low-molecular mass complement C1q by cultured human monocytes and macrophages.Biochem. J. 257, 477\u2013486.","journal-title":"Biochem. J."},{"key":"BF02815080_CR19","doi-asserted-by":"crossref","first-page":"7767","DOI":"10.1074\/jbc.271.13.7767","volume":"271","author":"H. Y. Hsu","year":"1996","unstructured":"Hsu H. Y., Nicholson A. C., and Hajjar D. P. (1996) Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulated.J. Biol. Chem. 271, 7767\u20137773.","journal-title":"J. Biol. Chem."},{"key":"BF02815080_CR20","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0197-4580(96)00107-8","volume":"17","author":"M. Hull","year":"1996","unstructured":"Hull M., Fiebich B. L., Lieb K., Strauss S., Berger M., Volk B., et al. (1996) Interleukin-6-associated inflammatory processes in Alzheimer\u2019s disease: New therapeutic options.Neurobiol. Aging 17, 795\u2013800.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR21","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.4049\/jimmunol.152.10.5050","volume":"152","author":"H Jiang","year":"1994","unstructured":"Jiang H, Burdick D, Glabe C. G., Cotman C. W., and Tenner A. J. (1994) Beta-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q a chain.J. Immunol. 152, 5050\u20135059.","journal-title":"J. Immunol."},{"key":"BF02815080_CR22","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.4049\/jimmunol.146.7.2324","volume":"146","author":"H. X. Jiang","year":"1991","unstructured":"Jiang H. X., Siegel J. N., and Gewurz H. (1991) Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1q.J. Immunol 146, 2324\u20132330.","journal-title":"J. Immunol"},{"key":"BF02815080_CR23","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0197-4580(92)90086-D","volume":"13","author":"S. A. Johnson","year":"1992","unstructured":"Johnson S. A., Lampert-Etchells M., Pasinetti G. M., Rozovsky I., and Finch C. E. (1992) Complement mRNA in the mammalian brain: responses to Alzheimer\u2019s disease and experimental brain lesioning.Neurobiol. Aging 13, 641\u2013648.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR24","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1006\/neur.1996.0069","volume":"5","author":"R. J. Kalaria","year":"1997","unstructured":"Kalaria R. J., Cohen D. L., and Premkumar D. R. D. (1997) Cellular aspects of the inflammatory response in Alzheimer\u2019s disease.Neurodegeneration 5, 497\u2013503.","journal-title":"Neurodegeneration"},{"key":"BF02815080_CR25","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0006-8993(96)01229-2","volume":"747","author":"A. Klegeris","year":"1997","unstructured":"Klegeris A., Walker D. G., and McGeer P. L. (1997a) Interaction of Alzheimer beta amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha.Brain Res. 747, 114\u2013121.","journal-title":"Brain Res."},{"key":"BF02815080_CR26","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0165-5728(97)00094-5","volume":"78","author":"A. Klegeris","year":"1997","unstructured":"Klegeris A., Walker D. G., and McGeer P. L. (1997b) Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373MG cells.J. Neuroimmunol. 78, 152\u2013161.","journal-title":"J. Neuroimmunol."},{"key":"BF02815080_CR27","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1089\/jir.1996.16.245","volume":"16","author":"M. Kolosov","year":"1996","unstructured":"Kolosov M., Kolosova I., and Leu R. W. (1996a) Stimulation of macrophage synthesis of complement C1q by interferon-\u03b3 mediated by endogenous interferon \u03b1\/\u03b2J. Interferon Res. 16, 245\u2013249.","journal-title":"J. Interferon Res."},{"key":"BF02815080_CR28","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1089\/jir.1996.16.209","volume":"16","author":"M. Kolosov","year":"1996","unstructured":"Kolosov M., Kolosova I., Zhou A., and Leu R. W. (1996b) Autocrine induction of macrophage synthesis of complement subcomponent C1q by endogenous interferon \u03b1\/\u03b2.J. Interferon Res. 16, 209\u2013215.","journal-title":"J. Interferon Res."},{"key":"BF02815080_CR29","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1006\/exnr.1995.1051","volume":"134","author":"A. R. Korotzer","year":"1995","unstructured":"Korotzer A. R., Watt J., Cribbs D., Tenner A. J., Burdick D., Glabe C., et al. (1995) Cultured rat microglia express C1q and receptor for C1q: implications for amyloid effects on microglia.Exp. Neurol. 134, 214\u201321.","journal-title":"Exp. Neurol."},{"key":"BF02815080_CR30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/BF02736847","volume":"7","author":"D. K. Lahiri","year":"1996","unstructured":"Lahiri D. K. and Farlow M. R. (1996) Differential effect of tacrine and physostigmine on the secretion of the beta-amyloid precursor protein in cell lines.J. Mol. Neurosci. 7, 41\u201349.","journal-title":"J. Mol. Neurosci."},{"key":"BF02815080_CR31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1042\/bj2800117","volume":"280","author":"D. F. Lappin","year":"1991","unstructured":"Lappin D. F. and Whaley K. (1991) Modulation of complement gene expression by glucocorticoids.Biochem. J. 280, 117\u2013123.","journal-title":"Biochem. J."},{"key":"BF02815080_CR32","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1432-1033.1990.tb19443.x","volume":"194","author":"D. F. Lappin","year":"1990","unstructured":"Lappin D. F., Birnie G. D., and Whaley K. (1990) Interferon-mediated transcriptional and post-transcriptional modulation of complement gene expression in human monocytes.Eur. J. Biochem. 194, 177\u2013184.","journal-title":"Eur. J. Biochem."},{"key":"BF02815080_CR33","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0165-5728(96)00030-6","volume":"67","author":"D. Lorton","year":"1996","unstructured":"Lorton D., Kocsis J. M., King L., Madden K., and Brunden K. R. (1996) Beta amyloid induces increased release of interleukin-1\u03b2 from lipopolysaccharide-activated human monocytes.J. Neuroimmunol. 67, 21\u201329.","journal-title":"J. Neuroimmunol."},{"key":"BF02815080_CR34","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"O. H. Lowry","year":"1951","unstructured":"Lowry O. H., Rosebrough N. J., Farr A. L., and Randal R. J. (1951) Protein measurement with the Folin phenol reagent.J. Biol. Chem. 193, 265\u2013275.","journal-title":"J. Biol. Chem."},{"key":"BF02815080_CR35","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0197-4580(96)00006-1","volume":"17","author":"L. F. Lue","year":"1996","unstructured":"Lue L. F., Brachova L., Walker D. G., and Rogers J. (1996) Characterization of glial cultures from rapid autopsies of Alzheimer\u2019s and control patients.Neurobiol. Aging 17, 421\u20139.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR36","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0165-0173(95)00011-9","volume":"21","author":"P. L. McGeer","year":"1995","unstructured":"McGeer P. L. and McGeer E. G. (1995) The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases.Brain Res. Rev. 21, 195\u2013218.","journal-title":"Brain Res. Rev."},{"key":"BF02815080_CR37","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0304-3940(89)90843-4","volume":"107","author":"P. L. McGeer","year":"1989","unstructured":"McGeer P. L., Akiyama H., Itagaki S., and McGeer E. G. (1989) Activation of the classical complement pathway in brain tissue of Alzheimer patients.Neurosci. Lett. 107, 341\u2013346.","journal-title":"Neurosci. Lett."},{"key":"BF02815080_CR38","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1212\/WNL.47.2.425","volume":"47","author":"P. L. McGeer","year":"1996","unstructured":"McGeer P. L., Schulzer M., and McGeer E. G. (1996) Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer\u2019s disease: a review of 17 epidemiologic studies.Neurology 47, 425\u2013432.","journal-title":"Neurology"},{"key":"BF02815080_CR39","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1055\/s-2007-1014297","volume":"27","author":"H. J. Moller","year":"1994","unstructured":"Moller H. J., Maurer I., and Saletu B. (1994) Placebo-controlled trial of the xanthine derivative propentofylline in dementia.Pharmacopsychiatry 27, 159\u2013165.","journal-title":"Pharmacopsychiatry"},{"key":"BF02815080_CR40","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0014-4886(92)90028-O","volume":"118","author":"G. M. Pasinetti","year":"1992","unstructured":"Pasinetti G. M., Johnson S. A., Rozovsky I., Lampert-Etchells M., Morgan D. G., Gordon M. N., et al. (1992) Complement C1qB and C4 mRNAs responses to lesioning in rat brain.Exp. Neurol. 118, 117\u2013125.","journal-title":"Exp. Neurol."},{"key":"BF02815080_CR41","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1128\/MCB.16.4.1419","volume":"16","author":"E. Petricoin","year":"1996","unstructured":"Petricoin E. 3rd, David M., Igarashi K., Benjamin C., Ling L., Goelz S., et al. (1996) Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase.Mol. Cell. Biol. 16, 1419\u20131424.","journal-title":"Mol. Cell. Biol."},{"key":"BF02815080_CR42","doi-asserted-by":"crossref","first-page":"3988","DOI":"10.4049\/jimmunol.147.11.3988","volume":"147","author":"F. Petry","year":"1991","unstructured":"Petry F., Reid K. B., and Loos M. (1991) Gene expression of the A- and B-chain of mouse C1q in different tissues and the characterization of the recombinant A-chain.J. Immunol. 147, 3988\u20133993.","journal-title":"J. Immunol."},{"key":"BF02815080_CR43","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/ana.410290207","volume":"29","author":"S. Peudenier","year":"1991","unstructured":"Peudenier S., Hery C., Montagnier L., and Tardieu M. (1991) Human microglial cells: Characterization in cerebral tissue and in primary culture, and study of their susceptibility to HIV-1 infection.Ann. Neurol. 29, 152\u2013161.","journal-title":"Ann. Neurol."},{"key":"BF02815080_CR44","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1006\/cimm.1994.1164","volume":"156","author":"J. Prieto","year":"1994","unstructured":"Prieto J., Eklund A., and Patarroyo M. (1994) Regulated expression of integrins and other adhesion molecules during differentiation of monocytes into macrophages.Cell. Immunol. 156, 191\u2013211.","journal-title":"Cell. Immunol."},{"key":"BF02815080_CR45","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1042\/bj2310729","volume":"231","author":"K. B. Reid","year":"1985","unstructured":"Reid K. B. (1985) Molecular cloning and characterization of the complementary DNA and gene coding for the B-chain of subcomponent C1q of the human complement system.Biochem. J. 231, 729\u2013735.","journal-title":"Biochem. J."},{"key":"BF02815080_CR46","first-page":"8","volume":"84","author":"K. B. Reid","year":"1989","unstructured":"Reid K. B. (1989) Chemistry and molecular genetics of C1q.Behring Inst. Mitt. 84, 8\u201319.","journal-title":"Behring Inst. Mitt."},{"key":"BF02815080_CR47","doi-asserted-by":"crossref","first-page":"10,016","DOI":"10.1073\/pnas.89.21.10016","volume":"89","author":"J. Rogers","year":"1992","unstructured":"Rogers J., Cooper N. R., Webster S., Schultz J., McGeer P. L., Styren S. D., et al. (1992) Complement activation by beta-amyloid in Alzheimer disease.Proc. Natl. Acad. Sci. USA 89, 10,016\u201310,020.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF02815080_CR48","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1212\/WNL.43.8.1609","volume":"43","author":"J. Rogers","year":"1993","unstructured":"Rogers J., Kirby L. C., Hempelman S. R., Berry D. L., McGeer P. L., Kaszniak A. W., et al. (1993) Clinical trial of indomethacin in Alzheimer\u2019s disease.Neurology 43, 1609\u20131611.","journal-title":"Neurology"},{"key":"BF02815080_CR49","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/0306-4522(94)90473-1","volume":"62","author":"I. Rozovsky","year":"1994","unstructured":"Rozovsky I., Morgan T. E., Willoughby D. A., Dugichi-Djordjevich M. M., Pasinetti G. M., Johnson S. A., et al. (1994) Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro.Neuroscience 62, 741\u2013758.","journal-title":"Neuroscience"},{"key":"BF02815080_CR50","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/(SICI)1098-1136(199607)17:3<225::AID-GLIA5>3.0.CO;2-#","volume":"17","author":"L. C. Schlichter","year":"1996","unstructured":"Schlichter L. C., Sakellaropoulos G., Ballyk B., Pennefather P. S., and Phipps D. J. (1996) Properties of K+ and Cl\u2212 channels and their involvement in proliferation of rat microglial cells.Glia 17, 225\u2013236.","journal-title":"Glia"},{"key":"BF02815080_CR51","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/jlb.59.4.555","volume":"59","author":"H. Schwende","year":"1996","unstructured":"Schwende H., Fitzke E., Ambs P., and Dieter P. (1996) Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3.J. Leukocyte Biol. 59, 555\u2013561.","journal-title":"J. Leukocyte Biol."},{"key":"BF02815080_CR52","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/0197-4580(95)00055-J","volume":"16","author":"L. M. Shaffer","year":"1995","unstructured":"Shaffer L. M., Dority M. D., Gupta-Bansal R., Frederickson R. C., Younkin S. G., and Brunden K. R. (1995) Amyloid beta protein (A beta) removal by neuroglial cells in culture.Neurobiol. Aging 16, 737\u2013745.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR53","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1042\/bj2330451","volume":"233","author":"A. J. Tenner","year":"1986","unstructured":"Tenner A. J. and Volkin D. B. (1986) Complement subcomponent C1q secreted by cultured human monocytes has subunit structure identical with that of serum C1q.Biochem. J. 233, 451\u2013458.","journal-title":"Biochem. J."},{"key":"BF02815080_CR54","first-page":"638","volume":"84","author":"P. K. Trinder","year":"1995","unstructured":"Trinder P. K., Faust D., Petry F., and Loos M. (1995) Modulation of mRNA expression and secretion of C1q in mouse macrophages by anti-inflammatory drugs and cAMP: evidence for the partial involvement of a pathway that includes cyclooxygenase, prostaglandin E2 and adenylate cyclase.Immunology 84, 638\u2013644.","journal-title":"Immunology"},{"key":"BF02815080_CR55","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nm0197-77","volume":"3","author":"P Velazquez","year":"1997","unstructured":"Velazquez P, Cribbs D. H., Poulos T. L., and Tenner A. J. (1997) Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer\u2019s disease pathogenesis.Nature Med. 3, 77\u201379.","journal-title":"Nature Med."},{"key":"BF02815080_CR56","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/jnr.490400407","volume":"40","author":"D. G. Walker","year":"1995","unstructured":"Walker D. G., Kim S. U., and McGeer P. L. (1995a) Complement and cytokine gene expression in cultured microglia derived from postmortem human brains.J. Neurosci. Res. 40, 478\u2013493.","journal-title":"J. Neurosci. Res."},{"key":"BF02815080_CR57","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0006-8993(95)00041-N","volume":"675","author":"D. G. Walker","year":"1995","unstructured":"Walker D. G., Yasuhara O., Patston P. A., McGeer E. G., and McGeer P. L. (1995b) Complement C1 inhibitor is produced by brain tissue and is cleaved in Alzheimer disease.Brain Res. 675, 75\u201382.","journal-title":"Brain Res."},{"key":"BF02815080_CR58","doi-asserted-by":"crossref","first-page":"8955","DOI":"10.1073\/pnas.92.19.8955","volume":"92","author":"Y. Wang","year":"1995","unstructured":"Wang Y., Rollins S. A., Madri J. A., and Matis L. A. (1995) Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease.Proc. Natl. Acad. Sci. USA 92, 8955\u20138959.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"BF02815080_CR59","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/jnr.490390412","volume":"39","author":"S. Webster","year":"1994","unstructured":"Webster S., O\u2019Barr S., and Rogers J. (1994) Enhanced aggregation and beta structure of amyloid beta peptide after coincubation with C1q.J. Neurosci. Res. 39, 448\u201356.","journal-title":"J. Neurosci. Res."},{"key":"BF02815080_CR60","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0197-4580(97)00042-0","volume":"18","author":"S. Webster","year":"1997","unstructured":"Webster S., Lue L.-F., Brachova L., Tenner A. J., McGeer P. L., Terai K., et al. (1997) Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer\u2019s disease.Neurobiol. Aging 18, 415\u2013421.","journal-title":"Neurobiol. Aging"},{"key":"BF02815080_CR61","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/00005072-199209000-00009","volume":"51","author":"K. Williams","year":"1992","unstructured":"Williams K., Bar-Or A., Ulvestad E., Olivier A., Antel J. P., and Yong V. W. (1992) Biology of adult human microglia in culture: Comparison with peripheral blood monocytes and astrocytes.J. Neuropathol. Exp. Neurol. 51, 538\u2013549.","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"BF02815080_CR62","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0161-5890(93)90111-N","volume":"30","author":"M. G. Wing","year":"1993","unstructured":"Wing M. G., Seilly D. J., Bridgman D. J., and Harrison R. A. (1993) Rapid isolation and biochemical characterization of rat C1 and C1q.Mol. Immunol. 30, 433\u2013440.","journal-title":"Mol. Immunol."},{"key":"BF02815080_CR63","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/jlb.59.4.575","volume":"59","author":"X. Zhang","year":"1996","unstructured":"Zhang X., Laubach V. E., Alley E. W., Edwards K. A., Sherman P. A., Russell S. W., et al. (1996) Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide\/interferon-gamma.J. Leukocyte Biol. 59, 575\u2013585.","journal-title":"J. Leukocyte Biol."},{"key":"BF02815080_CR64","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/jlb.50.5.453","volume":"50","author":"A. Q Zhou","year":"1991","unstructured":"Zhou A. Q, Herriott M. J., and Leu R. W. (1991) Kinetics of the biosynthesis of complement subcomponent C1q by murine macrophages: LPS immune complexes, and zymosan alone and in combination with interferon-gamma.J. Leukocyte Biol. 50, 453\u2013463.","journal-title":"J. Leukocyte Biol."}],"container-title":["Molecular and Chemical Neuropathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02815080.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/BF02815080\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/BF02815080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T22:12:02Z","timestamp":1708553522000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/BF02815080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,6]]},"references-count":64,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[1998,6]]}},"alternative-id":["BF02815080"],"URL":"https:\/\/doi.org\/10.1007\/bf02815080","relation":{},"ISSN":["1044-7393"],"issn-type":[{"value":"1044-7393","type":"print"}],"subject":[],"published":{"date-parts":[[1998,6]]}}}