{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T07:43:01Z","timestamp":1748590981782},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,4,9]],"date-time":"2018-04-09T00:00:00Z","timestamp":1523232000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"for scientific research from the Ministry of Health, Spain (Instituto de Salud Carlos III","award":["PI070675"],"award-info":[{"award-number":["PI070675"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neural Comput &amp; Applic"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00521-018-3473-6","type":"journal-article","created":{"date-parts":[[2018,4,9]],"date-time":"2018-04-09T09:53:49Z","timestamp":1523267629000},"page":"1219-1229","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcome prediction for salivary gland cancer using multivariate adaptative regression splines (MARS) and self-organizing maps (SOM)"],"prefix":"10.1007","volume":"32","author":[{"given":"Paloma","family":"Lequerica-Fern\u00e1ndez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Pe\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Iglesias-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Gonz\u00e1lez-Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Carlos","family":"De Vicente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,4,9]]},"reference":[{"key":"3473_CR1","unstructured":"Center for Disease Control Statistics. United States cancer statistics. Available at: http:\/\/www.apps.nccd.cdc.gov.\/uscs\/cancersbyraceandethnicity.aspx. (2014)"},{"key":"3473_CR2","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/MLG.0b013e318158f754","volume":"118","author":"JC Vicente De","year":"2008","unstructured":"De Vicente JC, Lequerica-Fern\u00e1ndez P, L\u00f3pez-Arranz JS, Esteban I, Fresno MF, Astudillo A (2008) Expression of matrix metalloproteinase-9 in high grade salivary gland carcinomas is associated with their metastatic potential. Laryngoscope 118:247\u2013251","journal-title":"Laryngoscope"},{"key":"3473_CR3","first-page":"3661","volume":"27","author":"P Lequerica-Fern\u00e1ndez","year":"2007","unstructured":"Lequerica-Fern\u00e1ndez P, Astudillo A, De Vicente JC (2007) Expression of vascular endothelial growth factor in salivary gland carcinomas correlates with lymph node metastasis. Anticancer Res 27:3661\u20133666","journal-title":"Anticancer Res"},{"key":"3473_CR4","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.humpath.2017.02.017","volume":"63","author":"K Hashimoto","year":"2017","unstructured":"Hashimoto K, Hayashi R, Mukaigawa T, Yamazaki M, Fujii S (2017) Concomitant expression of ezrin and HER2 predicts distant metastasis and poor prognosis of patients with salivary gland carcinomas. Hum Pathol 63:110\u2013119","journal-title":"Hum Pathol"},{"key":"3473_CR5","doi-asserted-by":"crossref","first-page":"29458","DOI":"10.18632\/oncotarget.15297","volume":"8","author":"Q Li","year":"2017","unstructured":"Li Q, Huang P, Zheng C, Wang J, Ge M (2017) Prognostic significance of p53 immunohistochemical expression in adenoid cystic carcinoma of the salivary glands: a meta-analysis. Oncotarget 8:29458\u201329473","journal-title":"Oncotarget"},{"key":"3473_CR6","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1002\/bjs.8980","volume":"100","author":"S Saadatmand","year":"2013","unstructured":"Saadatmand S, de Kruijf EM, Sajet A, Dekker-Ensink NG, van Nes JG, Putter H, Smit VT, van de Velde CJ, Liefers GJ, Kuppen PJ (2013) Expression of cell adhesion molecules and prognosis in breast cancer. Brit J Surg 100:252\u2013260","journal-title":"Brit J Surg"},{"key":"3473_CR7","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1002\/cncr.22647","volume":"109","author":"JF Carrillo","year":"2007","unstructured":"Carrillo JF, V\u00e1zquez R, Ram\u00edrez-Ortega MC, Cano A, Ochoa-Carrillo FJ, O\u00f1ate-Oca\u00f1a LF (2007) Multivariate prediction of the probability of recurrence in patients with carcinoma of the parotid gland. Cancer 109:2043\u20132051","journal-title":"Cancer"},{"key":"3473_CR8","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.ijom.2011.04.008","volume":"40","author":"P Lequerica-Fern\u00e1ndez","year":"2011","unstructured":"Lequerica-Fern\u00e1ndez P, Pe\u00f1a I, Villala\u00edn L, Rosado P, de Vicente JC (2011) Carcinoma of the parotid gland: developing prognostic indices. Int J Oral Maxillofac Surg 40:821\u2013828","journal-title":"Int J Oral Maxillofac Surg"},{"key":"3473_CR9","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1002\/cncr.24015","volume":"1","author":"VL Poorten Vander","year":"2009","unstructured":"Vander Poorten VL, Hart A, Vauterin T, Jeunen G, Schoenaers J, Hamoir M, Balm A, Stennert E, Guntinas-Lichius O, Delaere P (2009) Prognostic index for patients with parotid carcinoma. International external validation in a Belgian-German database. Cancer 1:540\u2013550","journal-title":"Cancer"},{"issue":"1","key":"3473_CR10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1214\/aos\/1176347963","volume":"19","author":"JH Friedman","year":"1991","unstructured":"Friedman JH (1991) Multivariate Adaptive Regression Splines. The Annals of Statistics 19(1):1\u201367","journal-title":"The Annals of Statistics"},{"issue":"7","key":"3473_CR11","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/j.mcm.2010.03.019","volume":"52","author":"L\u00c1 Men\u00e9ndez","year":"2010","unstructured":"Men\u00e9ndez L\u00c1, de Cos Juez FJ, Lasheras FS, Riesgo JA\u00c1 (2010) Artificial neural networks applied to cancer detection in a breast screening programme. Math Comput Model 52(7):983\u2013991","journal-title":"Math Comput Model"},{"issue":"3\u20134","key":"3473_CR12","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1007\/s00521-012-1286-6","volume":"24","author":"R Senapati","year":"2014","unstructured":"Senapati R, Panda G, Dash PK (2014) Hybrid approach using KPSO and RLS for RBFNN design for breast cancer detection. Neural Comput Appl 24(3\u20134):745\u2013753","journal-title":"Neural Comput Appl"},{"key":"3473_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s00521-017-2844-8","author":"J Dawidowicz","year":"2017","unstructured":"Dawidowicz J (2017) Evaluation of a pressure head and pressure zones in water distribution systems by artificial neural networks. Neural Comput Appl. https:\/\/doi.org\/10.1007\/s00521-017-2844-8","journal-title":"Neural Comput Appl"},{"key":"3473_CR14","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.resourpol.2015.03.004","volume":"45","author":"FS Lasheras","year":"2015","unstructured":"Lasheras FS, de Cos Juez FJ, S\u00e1nchez AS, Krzemie\u0144 A, Fern\u00e1ndez PR (2015) Forecasting the COMEX copper spot price by means of neural networks and ARIMA models. Resour Policy 45:37\u201343","journal-title":"Resour Policy"},{"key":"3473_CR15","doi-asserted-by":"publisher","first-page":"729","DOI":"10.3390\/ma10070729","volume":"10","author":"M Men\u00e9ndez-\u00c1lvarez","year":"2017","unstructured":"Men\u00e9ndez-\u00c1lvarez M, Mu\u00f1\u00edz-Sierra H, S\u00e1nchez-Lasheras F, de Cos-Juez FJ (2017) A parametric model of the LARCODEMS heavy media separator by means of multivariate adaptive regression splines. Materials 10:729","journal-title":"Materials"},{"key":"3473_CR16","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.apenergy.2016.07.052","volume":"180","author":"Y Li","year":"2016","unstructured":"Li Y, He Y, Su Y, Shu L (2016) Forecasting the daily power output of a grid-connected photovoltaic system based on multivariate adaptive regression splines. Appl Energ 180:392\u2013401","journal-title":"Appl Energ"},{"key":"3473_CR17","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.scitotenv.2012.04.068","volume":"430","author":"PJG Nieto","year":"2012","unstructured":"Nieto PJG, Fern\u00e1ndez JRA, Lasheras FS, de Cos-Juez FJ, Mu\u00f1iz CD (2012) A new improved study of cyanotoxins presence from experimental cyanobacteria concentrations in the Trasona reservoir (Northern Spain) using the MARS technique. Sci Total Environ 430:88\u201392","journal-title":"Sci Total Environ"},{"issue":"3","key":"3473_CR18","first-page":"351","volume":"10","author":"J Andr\u00e9s De","year":"2011","unstructured":"De Andr\u00e9s J, S\u00e1nchez-Lasheras F, Lorca P, de Cos-Juez FJ (2011) A hybrid device of self organizing maps (SOM) and multivariate adaptive regression splines (MARS) for the forecasting of firms\u2019 bankruptcy. Account Manag Inf Syst 10(3):351","journal-title":"Account Manag Inf Syst"},{"key":"3473_CR19","first-page":"188","volume":"199","author":"JR Leathwick","year":"2006","unstructured":"Leathwick JR, Elith J, Hastie T (2006) Comparative performance of generalized additive models and multivariate adaptive regression splines for statistical modelling of species distributions. Ecol Eng 199:188\u2013196","journal-title":"Ecol Eng"},{"key":"3473_CR20","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1109\/5.58325","volume":"78","author":"T Kohonen","year":"1990","unstructured":"Kohonen T (1990) The self-organizing map. Proc IEEE 78:1464\u20131480","journal-title":"Proc IEEE"},{"key":"3473_CR21","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.eswa.2016.08.010","volume":"64","author":"F Ortega-Zamorano","year":"2016","unstructured":"Ortega-Zamorano F, Molina-Cabello MA, L\u00f3pez-Rubio E, Palomo EJ (2016) Smart motion detection sensor based on video processing using self-organizing maps. Expert Syst. Appl 64:476\u2013489","journal-title":"Expert Syst. Appl"},{"key":"3473_CR22","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.asoc.2017.03.011","volume":"60","author":"MA Valle","year":"2017","unstructured":"Valle MA, Ruz GA, Mas\u00edas VH (2017) Using self-organizing maps to model turnover of sales agents in a call center. Appl Soft Comput 60:763\u2013774","journal-title":"Appl Soft Comput"},{"key":"3473_CR23","volume-title":"WHO classification of head and neck tumours","year":"2017","unstructured":"El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (eds) (2017) WHO classification of head and neck tumours. International Agency for Research on Cancer, Lyon"},{"key":"3473_CR24","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1016\/j.soc.2015.03.011","volume":"24","author":"A Panwar","year":"2015","unstructured":"Panwar A, Kozel JA, Lydiatt WM (2015) Cancers of major salivary glands. Surg Oncol Clin N Am 24:615\u2013633","journal-title":"Surg Oncol Clin N Am"},{"key":"3473_CR25","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.oraloncology.2005.06.014","volume":"42","author":"D Andreadis","year":"2006","unstructured":"Andreadis D, Epivatianos A, Poulopoulos A, Nomikos A, Papazoglou G, Antoniades D, Barbatis C (2006) Detection of C-KIT (CD117) molecule in benign and malignant salivary gland tumours. Oral Oncol 42:57\u201365","journal-title":"Oral Oncol"},{"key":"3473_CR26","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1007\/s12105-014-0541-9","volume":"8","author":"JA Bishop","year":"2014","unstructured":"Bishop JA, Yonescu R, Batista D, Yemelyanova A, Ha PK, Westra WH (2014) Mucoepidermoid carcinoma does not harbor transcriptionally active high risk human papillomavirus even in the absence of the MAML2 translocation. Head Neck Pathol 8:298\u2013302","journal-title":"Head Neck Pathol"},{"key":"3473_CR27","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1016\/j.jcms.2014.07.008","volume":"42","author":"S Liu","year":"2014","unstructured":"Liu S, Ruan M, Li S, Wang L, Yang W (2014) Increased expression of MUC1 predicts poor survival in\u00a0salivary\u00a0gland mucoepidermoid carcinoma. J Craniomaxillofac Surg 42:1891\u20131896","journal-title":"J Craniomaxillofac Surg"},{"key":"3473_CR28","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1111\/jop.12170","volume":"43","author":"L Siyi","year":"2014","unstructured":"Siyi L, Shengwen L, Min R, Wenjun Y, Lizheng W, Chenping Z (2014) Increased expression of\u00a0MUC-1\u00a0has close relation with patient survivor in high-grade\u00a0salivary\u00a0gland mucoepidermoid carcinoma. J Oral Pathol Med 43:579\u2013584","journal-title":"J Oral Pathol Med"},{"key":"3473_CR29","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.yexmp.2011.01.007","volume":"90","author":"CF Gon\u00e7alves","year":"2011","unstructured":"Gon\u00e7alves CF, Morais MO, Alencar RdeC, Mota ED, Silva TA, Batista AC, Mendon\u00e7a EF (2011) Expression of Ki-67 and MUC1 In mucoepidermoid carcinomas of young and adult patients: prognostic implications. Exp Mol Pathol 90:271\u2013275","journal-title":"Exp Mol Pathol"},{"key":"3473_CR30","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/lary.21164","volume":"121","author":"N Shemirani","year":"2011","unstructured":"Shemirani N, Osipov V, Kolker A, Khampang P, Kerschner JE (2011) Expression of mucin (MUC) genes in mucoepidermoid carcinoma. Laryngoscope 121:167\u2013170","journal-title":"Laryngoscope"},{"key":"3473_CR31","first-page":"22034518760297","volume":"1","author":"T Fukusumi","year":"2018","unstructured":"Fukusumi T, Califano JA (2018) The NOTCH pathway in head and neck squamous cell carcinoma. J Dent Res 1:22034518760297","journal-title":"J Dent Res"},{"key":"3473_CR32","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1016\/j.oraloncology.2014.10.007","volume":"51","author":"S Weert van","year":"2015","unstructured":"van Weert S, van der Waal I, Witte BI, Leemans CR, Bloemena E (2015) Histopathological grading of adenoid cystic carcinoma of the head and neck: analysis of currently used grading systems and proposal for a simplified grading scheme. Oral Oncol 51:71\u201376","journal-title":"Oral Oncol"},{"key":"3473_CR33","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.sdentj.2009.12.001","volume":"22","author":"MM Ahmed","year":"2010","unstructured":"Ahmed MM, Abo-Hager EA (2010) Differential expression of c-kit and CD43 in histological subtypes of adenoid cystic carcinoma of salivary gland. Saudi Dent J 22:27\u201334","journal-title":"Saudi Dent J"},{"key":"3473_CR34","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1097\/PAI.0b013e318036bf8c","volume":"16","author":"RR Seethala","year":"2008","unstructured":"Seethala RR, Pasha TL, Raghunath PN, Livolsi VA, Zhang PJ (2008) The selective expression of\u00a0CD43\u00a0in adenoid cystic carcinoma. Appl Immunohistochem Mol Morphol 16:165\u2013172","journal-title":"Appl Immunohistochem Mol Morphol"},{"key":"3473_CR35","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.otc.2015.11.001","volume":"49","author":"AG Lewis","year":"2016","unstructured":"Lewis AG, Tong T, Maghami E (2016) Diagnosis and management of malignant salivary gland tumors of the parotid gland. Otolaryngol Clin North Am 49:343\u2013380","journal-title":"Otolaryngol Clin North Am"},{"key":"3473_CR36","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1002\/1097-0142(19910101)67:1<172::AID-CNCR2820670129>3.0.CO;2-X","volume":"67","author":"JE Lewis","year":"1991","unstructured":"Lewis JE, Olsen KD, Weiland LH (1991) Acinic cell carcinoma. Clinicopathologic review. Cancer 67:172\u2013179","journal-title":"Cancer"},{"key":"3473_CR37","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.joms.2016.06.185","volume":"75","author":"Y Liu","year":"2017","unstructured":"Liu Y, Su M, Yang Y, Zhao B, Qin L, Han Z (2017) Prognostic factors associated with decreased survival in patients with acinic cell carcinoma of the parotid gland. J Oral Maxillofac Surg 75:416\u2013422","journal-title":"J Oral Maxillofac Surg"},{"key":"3473_CR38","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1016\/B978-0-7216-9788-8.50024-1","volume-title":"Atlas of head and neck pathology","author":"BM Wenig","year":"2008","unstructured":"Wenig BM (2008) Section\u00a04: major and minor salivary glands. Neoplasms of the salivary glands. In: Wenig BM (ed) Atlas of head and neck pathology, 2nd edn. Elsevier, Philadelphia, pp 582\u2013702","edition":"2"},{"key":"3473_CR39","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.oooo.2016.06.005","volume":"122","author":"YH Hu","year":"2016","unstructured":"Hu YH, Zhang CY, Xia RH, Tian Z, Wang LZ, Li J (2016) Prognostic factors of carcinoma ex pleomorphic adenoma of the salivary glands, with emphasis on the widely invasive carcinoma: a clinicopathologic analysis of 361 cases in a Chinese population. Oral Surg Oral Med Oral Pathol Oral Radiol 122:598\u2013608","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"issue":"Suppl 1","key":"3473_CR40","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3109\/0284186X.2015.1114671","volume":"55","author":"K Bj\u00f8rndal","year":"2016","unstructured":"Bj\u00f8rndal K, Larsen SR, Therkildsen MH, Kristensen CA, Charabi B, Andersen E, Overgaard J, Schytte S, Pedersen HB, Andersen LI, Johansen J, Godballe C (2016) Danish Head and Neck Cancer Group (DAHANCA) and Academy of Geriatric Cancer Research (AgeCare). Does age affect prognosis in salivary gland carcinoma patients? A national Danish study. Acta Oncol 55(Suppl 1):19\u201322","journal-title":"Acta Oncol"}],"container-title":["Neural Computing and Applications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00521-018-3473-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00521-018-3473-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00521-018-3473-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,31]],"date-time":"2020-10-31T09:42:09Z","timestamp":1604137329000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00521-018-3473-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,9]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["3473"],"URL":"https:\/\/doi.org\/10.1007\/s00521-018-3473-6","relation":{},"ISSN":["0941-0643","1433-3058"],"issn-type":[{"value":"0941-0643","type":"print"},{"value":"1433-3058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,9]]},"assertion":[{"value":"2 February 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors report no conflicts of interest in this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}