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Since designing a Fuzzy System (FS) can be considered one of the most complex optimization problems, many meta-heuristic optimizations have been developed to design FS structures. This paper aims to design a Takagi\u2013Sugeno\u2013Kang fuzzy Systems (TSK-FS) structure by generating the required fuzzy rules and selecting the most influential parameters for these rules. In this context, a new hybrid nature-inspired algorithm is proposed, namely Genetic\u2013Grey Wolf Optimization (GGWO) algorithm, to optimize TSK-FSs. In GGWO, a hybridization of the genetic algorithm (GA) and the grey wolf optimizer (GWO) is applied to overcome the premature convergence and poor solution exploitation of the standard GWO. Using genetic crossover and mutation operators accelerates the exploration process and efficiently reaches the best solution (rule generation) within a reasonable time. The proposed GGWO is tested on several benchmark functions compared with other nature-inspired optimization algorithms. The result of simulations applied to the fuzzy control of nonlinear plants shows the superiority of GGWO in designing TSK-FSs with high accuracy compared with different optimization algorithms in terms of Root Mean Squared Error (RMSE) and computational time.\n<\/jats:p>","DOI":"10.1007\/s00521-022-07356-5","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T19:02:37Z","timestamp":1653937357000},"page":"17051-17069","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A hybrid Genetic\u2013Grey Wolf Optimization algorithm for optimizing Takagi\u2013Sugeno\u2013Kang fuzzy systems"],"prefix":"10.1007","volume":"34","author":[{"given":"Sally M.","family":"Elghamrawy","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9989-6681","authenticated-orcid":false,"given":"Aboul Ella","family":"Hassanien","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,5,30]]},"reference":[{"issue":"3","key":"7356_CR1","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/S0019-9958(65)90241-X","volume":"8","author":"LA Zadeh","year":"1965","unstructured":"Zadeh LA (1965) Fuzzy sets. 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