{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:43:15Z","timestamp":1760028195887},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Artif Life Robotics"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1007\/s10015-008-0505-9","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T10:27:57Z","timestamp":1229164077000},"page":"10-17","source":"Crossref","is-referenced-by-count":11,"title":["Stochastic determinism underlying life: systematic theory for assisting the synthesis of artificial cells and new medicines"],"prefix":"10.1007","volume":"13","author":[{"given":"Ken","family":"Naitoh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,12,14]]},"reference":[{"key":"505_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4613-8476-2_1","volume-title":"The algorithmic beauty of plants","author":"P. Prusinkiewicz","year":"1990","unstructured":"Prusinkiewicz P, Lindenmayer A (1990) The algorithmic beauty of plants. Springer, NY, pp 1\u2013228"},{"key":"505_CR2","first-page":"1","volume-title":"On growth and form","author":"D. Thompson","year":"1961","unstructured":"Thompson D (1961) On growth and form. Cambridge University Press, Cambridge, pp 1\u2013359"},{"key":"505_CR3","doi-asserted-by":"crossref","unstructured":"Ingber DE (1998) The architecture of life. Sci Am 52","DOI":"10.1038\/scientificamerican0198-48"},{"key":"505_CR4","first-page":"1","volume-title":"Topobiology","author":"G. Edelman","year":"1988","unstructured":"Edelman G (1988) Topobiology. Basic Books, New York, pp 1\u2013371"},{"issue":"4096","key":"505_CR5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1126\/science.181.4096.223","volume":"181","author":"C. Anfinsen","year":"1973","unstructured":"Anfinsen C (1973) Principles that govern the folding of protein chains. Science 181(4096):223\u2013230","journal-title":"Science"},{"issue":"3","key":"505_CR6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/nrm1589","volume":"6","author":"H.J. Dyson","year":"2005","unstructured":"Dyson HJ, Wright PE (2005) Intrinsically unstructured proteins and their functions. Nature Rev Mol Cell Biol 6(3):197\u2013208","journal-title":"Nature Rev Mol Cell Biol"},{"issue":"4","key":"505_CR7","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.jmb.2006.04.016","volume":"359","author":"Y. Minezaki","year":"2006","unstructured":"Minezaki Y, Homma K, Kinjo AR, et al (2006) Human transcription factors contain a high fraction of intrinsically disordered regions essential for transcriptional regulation. J Mol Biol 359(4):1137\u20131149","journal-title":"J Mol Biol"},{"key":"505_CR8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.2978\/jsas.12.223","volume":"12","author":"K. Naitoh","year":"2000","unstructured":"Naitoh K (2000) Mesoscopic kinetic theory for fluid phenomena and biochemical reaction processes. J Adv Sci 12:223\u2013230 (also in the International Institute of Advanced Studies (IIAS) Report, 2001)","journal-title":"J Adv Sci"},{"key":"505_CR9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF03167356","volume":"18","author":"K. Naitoh","year":"2001","unstructured":"Naitoh K (2001) Cyto-fluid dynamic theory. Jpn J Indust Appl Math 18:75\u2013105 (also published in Trans JSAM, 2003)","journal-title":"Jpn J Indust Appl Math"},{"key":"505_CR10","first-page":"1","volume-title":"Gene engine and machine engine","author":"K. Naitoh","year":"2006","unstructured":"Naitoh K (2006) Gene engine and machine engine. Springer, Tokyo, pp 1\u2013251"},{"key":"505_CR11","first-page":"58","volume":"6","author":"K. Naitoh","year":"2005","unstructured":"Naitoh K (2005) Basic pattern underlying life. Nikkei Sci 6:58\u201365","journal-title":"Nikkei Sci"},{"key":"505_CR12","doi-asserted-by":"crossref","unstructured":"Naitoh K (2001) Cytofluid dynamic theory of the origin of base, information, and function. Proceedings of the 6th International Symposium on Artificial Life and Robotics (AROB6), Vol 2, pp 357\u2013360 (also in Naitoh K (2002) Artif Life Robotics 6(1\/2):82\u201386, and Naitoh K (2005) Self-organising mechanism of biosystems. Artif Life Robotics 9:96\u201398)","DOI":"10.1007\/s10015-004-0338-0"},{"key":"505_CR13","unstructured":"Banjo S (2004) Fuel cell parasitized by thermophile. Master\u2019s Thesis, Yamagata University (directed by Ken Naitoh)"},{"key":"505_CR14","unstructured":"Naitoh K (2004) Bioinformatics based on continuum mechanics. Proceedings of the European Congress on Computational Methods in Applied Science and Engineering (ECCOMAS), pp 1\u20137"},{"key":"505_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/26.1.1","volume":"26","author":"D.A. Benson","year":"1998","unstructured":"Benson DA, et al (1998) Nucleic Acids Res 26:1 (also in Benson DA, et al (2003) Nucleic Acids Res 31:23)","journal-title":"Nucleic Acids Res"},{"key":"505_CR16","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1093\/nar\/25.5.955","volume":"25","author":"T.M. Lowe","year":"1997","unstructured":"Lowe TM, Eddy SR (1997) Nucleic Acids Res 25:955 (available at http:\/\/rna.wustl.edu\/tRNAdb\/ )","journal-title":"Nucleic Acids Res"},{"key":"505_CR17","unstructured":"JCM on-line catalogue, Japan Collection of Microorganisms, Riken (Institute of Physical and Chemical Research) http:\/\/www.jcm.riken.go.jp\/"},{"key":"505_CR18","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1093\/nar\/28.1.292","volume":"28","author":"Y. Nakamura","year":"2000","unstructured":"Nakamura Y, Gojobori T, Ikemura T (2000) Nucl Acids Res 28:292 (available at http:\/\/www.kazusa.or.jp\/codon\/ )","journal-title":"Nucl Acids Res"},{"key":"505_CR19","unstructured":"DNA Data Bank of Japan, http:\/\/www.ddbj.nig.ac.jp\/"},{"key":"505_CR20","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1126\/science.1060786","volume":"292","author":"W.K. Johnston","year":"2001","unstructured":"Johnston WK, Unrau PJ, Lawrence MS, et al (2001) RNA-catalyzed RNA polymerization: accurate and general RNA-templated primer extension. Science 292:1319\u20131325","journal-title":"Science"},{"key":"505_CR21","unstructured":"Watson JD, et al (1987) Molecular biology of the gene. 4th edn. Benjamin\/Cummings, Menlo Park (in Japanese, TDU, pp 1\u20131163)"},{"key":"505_CR22","unstructured":"Naitoh K, Ueki S (2008) Asymmetry underlining protein. To be published in Proceedings of the 13th international symposium on artificial life and robotics, 1\u20132"},{"key":"505_CR23","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1242\/jcs.92.2.303","volume":"92","author":"K. Homma","year":"1989","unstructured":"Homma K, Hastings JW (1989) Cell growth kinetics, division asymmetry and volume control at division in the marine dinoflagellate Gonyaulax polyedra. J Cell Sci 92:303\u2013318","journal-title":"J Cell Sci"},{"key":"505_CR24","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2516\/ogst:1999016","volume":"54","author":"K. Naitoh","year":"1999","unstructured":"Naitoh K (1999) Cyto-fluid dynamic theory for atomization processes. Oil Gas Sci Technol 54:205\u2013210","journal-title":"Oil Gas Sci Technol"},{"key":"505_CR25","first-page":"1","volume-title":"Developmental biology","author":"G. Scott","year":"2005","unstructured":"Scott G (2005) Developmental biology, 8th edn. Sinauer, MA, pp 1\u2013750","edition":"8th edn."},{"key":"505_CR26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/scientificamerican0490-56","volume":"262","author":"K.B. Mullis","year":"1990","unstructured":"Mullis KB (1990) The unusual origins of the polymerase chain reaction. Sci Am 262:56\u201365","journal-title":"Sci Am"},{"key":"505_CR27","first-page":"1","volume-title":"Steps toward life","author":"M. Eigen","year":"1992","unstructured":"Eigen M (1992) Steps toward life. Oxford University Press, Oxford, pp 1\u2013173"},{"key":"505_CR28","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0022-2836(86)90166-X","volume":"188","author":"G.F. Joyce","year":"1986","unstructured":"Joyce GF, Orgel LE (1986) Non-enzymic template-directed synthesis on RNA random copolymers: poly (C,G) templates. J Mol Biol 188:433\u2013441","journal-title":"J Mol Biol"},{"issue":"5","key":"505_CR29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/scientificamerican1186-64","volume":"255","author":"T. Cech","year":"1986","unstructured":"Cech T (1986) RNA as an enzyme. Sci Am 255(5):64\u201375","journal-title":"Sci Am"},{"key":"505_CR30","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/319618a0","volume":"319","author":"W. Gilbert","year":"1986","unstructured":"Gilbert W (1986) The RNA world. Nature (London) 319:618","journal-title":"Nature (London)"},{"key":"505_CR31","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1126\/science.1060786","volume":"292","author":"W.K. Johnston","year":"2001","unstructured":"Johnston WK, Unrau PJ, Lawrence MS, et al (2001) RNA-catalyzed RNA polymerization. Science 292:1319\u20131325","journal-title":"Science"},{"key":"505_CR32","unstructured":"Shimizu M (1996) Seimei no Honshitsu to Kigen. Kyoritsu"},{"key":"505_CR33","doi-asserted-by":"crossref","unstructured":"Naitoh K (2008) Inevitability of nTP: information-energy carriers. To be published in Proceedings of the 13th international symposium on artificial life and robotics, 1\u20134","DOI":"10.1007\/s10015-008-0548-y"},{"key":"505_CR34","doi-asserted-by":"crossref","unstructured":"Prive GG, Heinemann U, Chandrasegaren S, et al (1987) Helix geometry, hydration, and G-A mismatch in a B-DNA decamer. Science 238","DOI":"10.1126\/science.3310237"},{"key":"505_CR35","doi-asserted-by":"crossref","unstructured":"Saenger W, Hunter WH, Kennard O (1986) DNA conformation is determined by economics in the hydration of phosphate groups. Nature 324","DOI":"10.1038\/324385a0"},{"key":"505_CR36","doi-asserted-by":"crossref","unstructured":"Naitoh K, Yahiro M (2008) Inevitability of spiral shape in DNA. To be published in Proceedings of the 13th international symposium on artificial life and robotics, 1\u20134","DOI":"10.1007\/s10015-008-0547-z"},{"key":"505_CR37","first-page":"1","volume-title":"Chemistry for biologists","author":"J. Fisher","year":"2004","unstructured":"Fisher J, Arnold JRP (2004) Chemistry for biologists, 2nd edn. BIOS, Abinden, UK, pp 1\u2013288","edition":"2nd edn."},{"key":"505_CR38","first-page":"1","volume-title":"Nucleic acids","author":"V.A. Bloomfield","year":"2000","unstructured":"Bloomfield VA, Crothers DM, Tinoco I (2000) Nucleic acids. University Science Books, CA, pp 1\u2013794"},{"key":"505_CR39","unstructured":"Tatsumi T (1998) Fluid dynamics. Baifukan (in Japanese), pp 1\u2013453"},{"key":"505_CR40","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF03167398","volume":"15","author":"K. Naitoh","year":"1998","unstructured":"Naitoh K (1998) Macroscopic kinetic equation for a genetic algorithm. Jpn J Indust Appl Math 15:87\u2013133","journal-title":"Jpn J Indust Appl Math"},{"key":"505_CR41","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1299\/jsmec.41.398","volume":"41","author":"K. Naitoh","year":"1998","unstructured":"Naitoh K (1998) Introns for accelerating quasi-macroevolution. JSME Int J Ser C 41:398\u2013405","journal-title":"JSME Int J Ser C"}],"container-title":["Artificial Life and Robotics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10015-008-0505-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10015-008-0505-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10015-008-0505-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T19:26:14Z","timestamp":1632770774000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10015-008-0505-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["505"],"URL":"https:\/\/doi.org\/10.1007\/s10015-008-0505-9","relation":{},"ISSN":["1433-5298","1614-7456"],"issn-type":[{"value":"1433-5298","type":"print"},{"value":"1614-7456","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}