{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,21]],"date-time":"2023-05-21T07:10:18Z","timestamp":1684653018505},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2008,11,21]],"date-time":"2008-11-21T00:00:00Z","timestamp":1227225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Poiesis Prax"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1007\/s10202-008-0058-y","type":"journal-article","created":{"date-parts":[[2008,11,20]],"date-time":"2008-11-20T08:36:41Z","timestamp":1227170201000},"page":"65-77","source":"Crossref","is-referenced-by-count":1,"title":["The concept of the gene in psychiatric genetics and its consequences for the concept of mental illness"],"prefix":"10.1007","volume":"6","author":[{"given":"Vanessa","family":"Lux","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,11,21]]},"reference":[{"issue":"11","key":"58_CR1","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/sj.mp.4001340","volume":"8","author":"E Bacchelli","year":"2003","unstructured":"Bacchelli E, Blasi F, Biondolillo M, Lamb JA, Bonora E, Barnby G, Parr J, Beyer KS, Klauck SM, Poustka A, Bailey AJ, Monaco AP, Maestrini E, International Molecular Genetic Study of Autism Consortium (IMGSAC) (2003) Screening of nine candidate genes for autism on chromosome 2q reveals rare non-synonymous variants in the cAMP-GEFII gene. Mol Psychiatry 8(11):916\u2013924 10.1038\/sj.mp.4001340","journal-title":"Mol Psychiatry"},{"issue":"3","key":"58_CR2","first-page":"25","volume":"3","author":"U Bailer","year":"2002","unstructured":"Bailer U, Aschauer H, Kasper S (2002) Genetik der Schizophrenie. J Neurol Neurochir Psychiatr 3(3):25\u201331","journal-title":"J Neurol Neurochir Psychiatr"},{"issue":"1","key":"58_CR3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1093\/schbul\/sbl049","volume":"33","author":"DL Braff","year":"2007","unstructured":"Braff DL, Freedman R, Schork NJ, Gottesman II (2007) Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull 33(1):21\u201332 10.1093\/schbul\/sbl049","journal-title":"Schizophr Bull"},{"key":"58_CR4","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s11920-001-0030-1","volume":"3","author":"E Bramon","year":"2001","unstructured":"Bramon E, Sham PC (2001) The common genetic liability between schizophrenia and bipolar disorder: a review. Curr Psychiatry Rep 3:332\u2013337 10.1007\/s11920-001-0030-1","journal-title":"Curr Psychiatry Rep"},{"key":"58_CR5","first-page":"55","volume-title":"Behavioral genetics in the postgenomic era","author":"LR Cardon","year":"2002","unstructured":"Cardon LR (2002) Practical barriers to identifying complex trait loci. In: Plomin R, Defires J, Craig IW, McGuffin P (eds) Behavioral genetics in the postgenomic era. American Psychological Association, Washington DC, pp 55\u201369"},{"issue":"7","key":"58_CR38","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nrn1925","volume":"7","author":"A Caspi","year":"2006","unstructured":"Caspi A, Moffitt TE (2006) Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci 7(7):583\u2013590 10.1038\/nrn1925","journal-title":"Nat Rev Neurosci"},{"key":"58_CR6","first-page":"31","volume-title":"Defining psychopathology in the 21st century. DSM-V\u2122 and beyond","author":"DS Charney","year":"2002","unstructured":"Charney DS, Barlow DH, Botteron K, Cohen JD, Goldman D, Gur RE, Lin K-M, L\u00f3pez JF, Meador-Woodruff JH, Moldin SO, Nestler EJ, Watson SJ, Zalcman SJ (2002) Neuroscience research agenda to guide development of a pathophysiologically based classification system. In: Helzer JE, Hudziak JJ (eds) Defining psychopathology in the 21st century. DSM-V\u2122 and beyond. American Psychopathological Association Series. American Psychiatric Publishing, Arlington, pp 31\u201383"},{"issue":"21","key":"58_CR7","doi-asserted-by":"crossref","first-page":"13675","DOI":"10.1073\/pnas.182412499","volume":"99","author":"I Chumakov","year":"2002","unstructured":"Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, Bougueleret L, Barry C, Tanaka H, La Rosa P, Puech A, Tahri N, Cohen-Akenine A, Delabrosse S, Lissarrague S, Picard FP, Maurice K, Essioux L, Millasseau P, Grel P, Debailleul V, Simon AM, Caterina D, Dufaure I, Malekzadeh K, Belova M, Luan JJ, Bouillot M, Sambucy JL, Primas G, Saumier M, Boubkiri N, Martin-Saumier S, Nasroune M, Peixoto H, Delaye A, Pinchot V, Bastucci M, Guillou S, Chevillon M, Sainz-Fuertes R, Meguenni S, Aurich-Costa J, Cherif D, Gimalac A, Van Duijn C, Gauvreau D, Ouellette G, Fortier I, Raelson J, Sherbatich T, Riazanskaia N, Rogaev E, Raeymaekers P, Aerssens J, Konings F, Luyten W, Macciardi F, Sham PC, Straub RE, Weinberger DR, Cohen N, Cohen D (2002) Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proc Natl Acad Sci USA 99(21):13675\u201313680 10.1073\/pnas.182412499","journal-title":"Proc Natl Acad Sci USA"},{"issue":"25","key":"58_CR8","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1093\/hmg\/10.25.2933","volume":"10","author":"S Cichon","year":"2001","unstructured":"Cichon S, Schumacher J, M\u00fcller DJ, H\u00fcrter M, Windemuth C, Strauch K, Hemmer S, Schulze TG, Schmidt-Wolf G, Albus M, Borrmann-Hassenbach M, Franzek E, Lanczik M, Fritze J, Kreiner R, Reuner U, Weigelt B, Minges J, Lichtermann D, Lerer B, Kanyas K, Baur MP, Wienker TF, Maier W, Rietschel M, Propping P, N\u00f6then MM (2001) A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. Hum Mol Genet 10(25):2933\u20132944 10.1093\/hmg\/10.25.2933","journal-title":"Hum Mol Genet"},{"key":"58_CR9","volume-title":"Irren ist menschlich. Lehrbuch der Psychiatrie und Psychotherapie","author":"K D\u00f6rner","year":"2002","unstructured":"D\u00f6rner K, Plog U, Teller C, Wendt F (2002) Irren ist menschlich. Lehrbuch der Psychiatrie und Psychotherapie, 2nd edn. Psychiatrie-Verlag, Bonn","edition":"2"},{"key":"58_CR39","first-page":"245","volume-title":"Defining psychopathology in the 21st century. DSM-VTM and beyond","author":"Sv Faraone","year":"2002","unstructured":"Faraone SV (2002) Defining genetically meaningful classes of psychopathology. In: Helzer JE, Hudziak JJ (eds) Defining psychopathology in the 21st century. DSM-VTM and beyond. American Psychopathological Association Series. American Psychiatric Publishing, Arlington, pp 245\u2013248"},{"issue":"1","key":"58_CR10","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/ng792","volume":"30","author":"SE Fisher","year":"2002","unstructured":"Fisher SE, Francks C, Marlow AJ, MacPhie IL, Newbury DF, Cardon LR, Ishikawa-Brush Y, Richardson AJ, Talcott JB, Gay\u00e1n J, Olson RK, Pennington BF, Smith SD, DeFries JC, Stein JF, Monaco AP (2002) Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia. Nat Genet 30(1):86\u201391 10.1038\/ng792","journal-title":"Nat Genet"},{"key":"58_CR11","first-page":"63","volume-title":"Etymology and strategic intentions, in advances in genetics and genomics: implications for psychiatry","author":"II Gottesman","year":"2005","unstructured":"Gottesman II, Gould TD (2005) The endophenotype concept in psychiatry. In: Andreasen NC (ed) Etymology and strategic intentions, in advances in genetics and genomics: implications for psychiatry. American Psychiatric Publishing, Washington DC, pp 63\u201384"},{"key":"58_CR40","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1073\/pnas.58.1.199","volume":"58","author":"II Gottesman","year":"1967","unstructured":"Gottesman II, Shields J (1967) A polygenic theory of schizophrenia. Proc Natl Acad Sci USA 58:199\u2013205 10.1073\/pnas.58.1.199","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"58_CR12","first-page":"27","volume":"60","author":"EL Grigorenko","year":"1997","unstructured":"Grigorenko EL, Wood FB, Meyer MS, Hart LA, Speed WC, Shuster A, Pauls DL (1997) Susceptibility loci for distinct components of developmental dyslexia on chromosomes 6 and 15. Am J Hum Genet 60(1):27\u201339","journal-title":"Am J Hum Genet"},{"key":"58_CR13","volume-title":"Defining psychopathology in the 21st century. DSM-V\u2122 and beyond","author":"JE Helzer","year":"2002","unstructured":"Helzer JE, Hudziak JJ (2002) Defining psychopathology in the 21st century. DSM-V\u2122 and beyond. American Psychopathological Association Series. American Psychiatric Publishing, Arlington"},{"key":"58_CR14","first-page":"171","volume-title":"Genetic governance. health, risk and ethics in the biotech era","author":"MR Herbert","year":"2005","unstructured":"Herbert MR (2005) More than code. From genetic reductionism to complex biological systems. In: Bunton R, Petersen A (eds) Genetic governance. health, risk and ethics in the biotech era. Routledge, Abingdon, pp 171\u2013188"},{"key":"58_CR15","first-page":"48","volume-title":"Genom und Umwelt. Berliner Studien zur Wissenschaftsphilosophie & Humanontogenetik vol 19","author":"R Hohlfeld","year":"2001","unstructured":"Hohlfeld R (2001) Kontroverse Leitbilder und Paradigmen in der Biomedizin. In: Wessel K-F, Z\u00e4nker KS, D\u00f6rner G, Tembrock G, Vogel F (eds) Genom und Umwelt. Berliner Studien zur Wissenschaftsphilosophie & Humanontogenetik vol 19. Kleine Verlag, Bielefeld, pp 48\u201356"},{"key":"58_CR16","volume-title":"Grundlegung der Psychologie","author":"K Holzkamp","year":"1983","unstructured":"Holzkamp K (1983) Grundlegung der Psychologie. Campus, Frankfurt\/M"},{"issue":"7","key":"58_CR17","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1176\/ajp.2006.163.7.1138","volume":"163","author":"KS Kendler","year":"2006","unstructured":"Kendler KS (2006) Reflections on the relationship between psychiatric genetics and psychiatric nosology. Am J Psychiatry 163(7):1138\u20131146 10.1176\/appi.ajp.163.7.1138","journal-title":"Am J Psychiatry"},{"key":"58_CR18","volume-title":"Pharmakogenetik: Implikationen f\u00fcr Patienten und Gesundheitswesen. Anspruch und Wirklichkeit der \u201eindividualisierten Medizin\u201d","author":"R Kollek","year":"2004","unstructured":"Kollek R, Feuerstein G, Schmedders M, van Aken J (2004) Pharmakogenetik: Implikationen f\u00fcr Patienten und Gesundheitswesen. Anspruch und Wirklichkeit der \u201eindividualisierten Medizin\u201d. Nomos, Baden-Baden"},{"key":"58_CR19","volume-title":"A research agenda for DSM-V","author":"DJ Kupfer","year":"2002","unstructured":"Kupfer DJ, First MB, Regier DA (2002) A research agenda for DSM-V. American Psychiatric Association, Washington DC"},{"key":"58_CR20","doi-asserted-by":"crossref","unstructured":"Licinio J, Wong ML (eds) (2002) Pharmacogenomics. The search for individualized therapies. Wiley VCH, Weinheim","DOI":"10.1002\/3527600752"},{"issue":"6","key":"58_CR21","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.1073\/pnas.042700699","volume":"99","author":"H Liu","year":"2002","unstructured":"Liu H, Heath SC, Sobin C, Roos JL, Galke BL, Blundell ML, Lenane M, Robertson B, Wijsman EM, Rapoport JL, Gogos JA, Karayiorgou M (2002) Genetic variation at the 22q11 PRODH2\/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc Natl Acad Sci USA 99(6):3717\u20133722 10.1073\/pnas.042700699","journal-title":"Proc Natl Acad Sci USA"},{"key":"58_CR22","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/01.psy.0000208630.79271.a0","volume":"68","author":"JM McCaffery","year":"2006","unstructured":"McCaffery JM, Frasure-Smith N, Dub\u00e9 M-P, Th\u00e9roux P, Rouleau GA, Duan Q, Lesp\u00e9rance F (2006) Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med 68:187\u2013200 10.1097\/01.psy.0000208630.79271.a0","journal-title":"Psychosom Med"},{"key":"58_CR41","first-page":"37","volume-title":"Research advances in genetics and genomics: implications for psychiatry","author":"KR Merikangas","year":"2005","unstructured":"Merikangas KR, Risch N (2005) Will the genomics revolution revolutionize psychiatry? In: Andreasen NC (ed) Research advances in genetics and genomics: implications for psychiatry. American Psychiatric Publishing, Washington DC, pp 37\u201361"},{"issue":"49","key":"58_CR23","first-page":"A3343","volume":"101","author":"MM N\u00f6then","year":"2004","unstructured":"N\u00f6then MM, Rietschel M, Propping P, Maier W (2004) Psychiatrische Genetik: Fortschriftt in der Ursachenforschung affektiver und schizophrener St\u00f6rungen. Dtsch Arztebl 101(49):A3343\u2013A3347","journal-title":"Dtsch Arztebl"},{"key":"58_CR24","volume-title":"Entwicklungswissenschaft. Entwicklungspsychologie\u2013Genetik\u2013Neuropsychologie","author":"F Petermann","year":"2004","unstructured":"Petermann F, Niebank K, Scheithauer H (2004) Entwicklungswissenschaft. Entwicklungspsychologie\u2013Genetik\u2013Neuropsychologie. Springer, Berlin"},{"key":"58_CR25","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1515\/9783110902211.177","volume-title":"Das genetische Wissen und die Zukunft des Menschen","author":"P Propping","year":"2003","unstructured":"Propping P, N\u00f6then MM (2003) Wozu Forschung mit genetischen Daten und Informationen? In: Honnefelder L, Mieth D, Propping P, Siep L, Wisemann C (eds) Das genetische Wissen und die Zukunft des Menschen. Walter de Gruyter, Berlin, pp 177\u2013185"},{"key":"58_CR26","volume-title":"Beitr\u00e4ge zur Philosophie der Genetik. Ethik in den Wissenschaften vol. 18","author":"C Rehmann-Sutter","year":"2005","unstructured":"Rehmann-Sutter C (2005) Zwischen den Molek\u00fclen. In: Mieth D (ed) Beitr\u00e4ge zur Philosophie der Genetik. Ethik in den Wissenschaften vol. 18. Narr Francke Attempto, T\u00fcbingen"},{"key":"58_CR27","first-page":"9","volume-title":"Gentherapie statt Psychotherapie?","author":"B Scholten","year":"2004","unstructured":"Scholten B (2004) Die Ergebnisse der Humangenetik\u2013eine Herausforderung an die klinische Psychologie. In: Scholten B (ed) Gentherapie statt Psychotherapie? Kein Abschied vom Sozialen! dgvt, T\u00fcbingen, pp 9\u201326"},{"issue":"1","key":"58_CR28","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1086\/301919","volume":"63","author":"G Schulte-Korne","year":"1998","unstructured":"Schulte-Korne G, Grimm T, Nothen MM, Muller-Myhsok B, Cichon S, Vogt IR, Propping P, Remschmidt H (1998) Evidence for linkage of spelling disability to chromosome 15. Am J Hum Genet 63(1):279\u2013282 10.1086\/301919","journal-title":"Am J Hum Genet"},{"key":"58_CR29","volume-title":"Naturgeschichte des Psychischen, vol 1 and 2","author":"V Schurig","year":"1975","unstructured":"Schurig V (1975) Naturgeschichte des Psychischen, vol 1 and 2. Campus, Frankfurt\/M"},{"key":"58_CR30","volume-title":"Die Entstehung des Bewu\u00dftseins","author":"V Schurig","year":"1976","unstructured":"Schurig V (1976) Die Entstehung des Bewu\u00dftseins. Campus, Frankfurt\/M"},{"issue":"2","key":"58_CR31","first-page":"103","volume":"26","author":"L Sher","year":"2001","unstructured":"Sher L (2001) Candidate gene studies in psychiatric disorders: promises and limitations. J Psychiatry Neurosci 26(2):103\u2013105","journal-title":"J Psychiatry Neurosci"},{"issue":"2","key":"58_CR32","first-page":"71","volume":"3","author":"M Sonnenmoser","year":"2004","unstructured":"Sonnenmoser M (2004) Genetik und Psyche: Bedeutung der Gene nicht \u00fcbersch\u00e4tzen. Dtsch Arztebl 3(2):71 et sqq et sqq","journal-title":"Dtsch Arztebl"},{"issue":"6","key":"58_CR33","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/hmg\/9.6.927","volume":"9","author":"SF Stoltenberg","year":"2000","unstructured":"Stoltenberg SF, Burmeister M (2000) Recent progress in psychiatric genetics\u2014some hope but no hype. Hum Mol Genet 9(6):927\u2013935 10.1093\/hmg\/9.6.927","journal-title":"Hum Mol Genet"},{"key":"58_CR34","first-page":"85","volume-title":"Research advances in genetics and genomics: implications for psychiatry","author":"LH Tecott","year":"2005","unstructured":"Tecott LH (2005) The genes and brains of mice and men. In: Andreasen NC (ed) Research advances in genetics and genomics: implications for psychiatry. American Psychiatric Publishing, Washington DC, pp 85\u2013108"},{"issue":"143","key":"58_CR35","first-page":"3","volume":"16","author":"O Tolmein","year":"2000","unstructured":"Tolmein O (2000) Wissen ohne Macht. Gen-ethischer Informationsdienst 16(143):3\u20134","journal-title":"Gen-ethischer Informationsdienst"},{"key":"58_CR36","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/79866","volume":"26","author":"JL Weiss","year":"2000","unstructured":"Weiss JL, Terwillinger JD (2000) How many diseases does it take to map a gene with SNPs? Nat Genet 26:151\u2013157 10.1038\/79866","journal-title":"Nat Genet"},{"issue":"2","key":"58_CR37","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1037\/0021-843X.86.2.103","volume":"86","author":"J Zubin","year":"1977","unstructured":"Zubin J, Spring B (1977) Vulnerability\u2014a new view of schizophrenia. J Abnorm Psychol 86(2):103\u2013124 10.1037\/0021-843X.86.2.103","journal-title":"J Abnorm Psychol"}],"container-title":["Poiesis &amp; Praxis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10202-008-0058-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10202-008-0058-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10202-008-0058-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,21]],"date-time":"2023-05-21T06:31:45Z","timestamp":1684650705000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10202-008-0058-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,21]]},"references-count":41,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["58"],"URL":"https:\/\/doi.org\/10.1007\/s10202-008-0058-y","relation":{},"ISSN":["1615-6609","1615-6617"],"issn-type":[{"value":"1615-6609","type":"print"},{"value":"1615-6617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,21]]}}}