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In this study, the technical feasibility, accuracy, and usability of a recently introduced silicone-like resin were evaluated for endovascular procedure simulations and technically compared to a commonly used standard clear resin. Fifty-four vascular models based on twenty-seven consecutive embolization cases were fabricated from preinterventional CT scans and each model was checked for printing success and accuracy by CT-scanning and digital comparison to its original CT data. Median deltas (\u0394) of luminal diameters were 0.35\u00a0mm for clear and 0.32\u00a0mm for flexible resin (216 measurements in total) with no significant differences (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Printing success was 85.2% for standard clear and 81.5% for the novel flexible resin. In conclusion, vascular 3D printing with silicone-like flexible resin was technically feasible and highly accurate. This is the first and largest consecutive case series of 3D-printed embolizations with a novel biological tissue mimicking material and is a promising next step in patient-specific procedure simulations in Interventional Radiology.<\/jats:p>","DOI":"10.1007\/s10278-021-00553-z","type":"journal-article","created":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T22:02:51Z","timestamp":1641592971000},"page":"9-20","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Vascular 3D Printing with a Novel Biological Tissue Mimicking Resin for Patient-Specific Procedure Simulations in Interventional Radiology: a Feasibility Study"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0037-5211","authenticated-orcid":false,"given":"R.","family":"Kaufmann","sequence":"first","affiliation":[]},{"given":"C. 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