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Inform. med."],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to investigate the effects of intravenous injection of iodine contrast agent on the tracheal diameter and lung volume. In this retrospective study, a total of 221 patients (71.1\u2009\u00b1\u200912.4\u00a0years, 174 males) who underwent vascular dynamic CT examination including chest were included. Unenhanced, arterial phase, and delayed-phase images were scanned. The tracheal luminal diameters at the level of the thoracic inlet and both lung volumes were evaluated by a radiologist using a commercial software, which allows automatic airway and lung segmentation. The tracheal diameter and both lung volumes were compared between the unenhanced vs. arterial and delayed phase using a paired <jats:italic>t<\/jats:italic>-test. The Bonferroni correction was performed for multiple group comparisons. The tracheal diameter in the arterial phase (18.6\u2009\u00b1\u20092.4\u00a0mm) was statistically significantly smaller than those in the unenhanced CT (19.1\u2009\u00b1\u20092.5\u00a0mm) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). No statistically significant difference was found in the tracheal diameter between the delayed phase (19.0\u2009\u00b1\u20092.4\u00a0mm) and unenhanced CT (<jats:italic>p<\/jats:italic>\u2009=\u20090.077). Both lung volumes in the arterial phase were 4131\u2009\u00b1\u20091051\u00a0mL which was significantly smaller than those in the unenhanced CT (4332\u2009\u00b1\u20091076\u00a0mL) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). No statistically significant difference was found in both lung volumes between the delayed phase (4284\u2009\u00b1\u20091054\u00a0mL) and unenhanced CT (<jats:italic>p<\/jats:italic>\u2009=\u20090.068). In conclusion, intravenous infusion of iodine contrast agent transiently decreased the tracheal diameter and both lung volumes.<\/jats:p>","DOI":"10.1007\/s10278-024-01071-4","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T18:01:51Z","timestamp":1709748111000},"page":"1609-1617","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Intravenous Infusion of Iodine Contrast Media on the Tracheal Diameter and Lung Volume Measured with Deep Learning-Based Algorithm"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0324-6562","authenticated-orcid":false,"given":"Koichiro","family":"Yasaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Saigusa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,6]]},"reference":[{"issue":"2","key":"1071_CR1","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1148\/radiol.220370","volume":"305","author":"H Umakoshi","year":"2022","unstructured":"Umakoshi H, Nihashi T, Takada A et al. 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