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Medical Image Analysis (MIA) has undergone a transformative shift with the integration of Artificial Intelligence (AI) techniques such as Machine Learning (ML) and Deep Learning (DL), promising advanced diagnostics and improved healthcare outcomes. Despite these advancements, a comprehensive understanding of the efficiency metrics, computational complexities, interpretability, and scalability of AI based approaches in MIA is essential for practical feasibility in real-world healthcare environments. Existing studies exploring AI applications in MIA lack a consolidated review covering the major MIA stages and specifically focused on evaluating the efficiency of AI based approaches. The absence of a structured framework limits decision-making for researchers, practitioners, and policymakers in selecting and implementing optimal AI approaches in healthcare. Furthermore, the lack of standardized evaluation metrics complicates methodology comparison, hindering the development of efficient approaches. This article addresses these challenges through a comprehensive review, taxonomy, and analysis of existing AI-based MIA approaches in healthcare. The taxonomy covers major image processing stages, classifying AI approaches for each stage based on method and further analyzing them based on image origin, objective, method, dataset, and evaluation metrics to reveal their strengths and weaknesses. Additionally, comparative analysis conducted to evaluate the efficiency of AI based MIA approaches over five publically available datasets: ISIC 2018, CVC-Clinic, 2018 DSB, DRIVE, and EM in terms of accuracy, precision, Recall, F-measure, mIoU, and specificity. The popular public datasets and evaluation metrics are briefly described and analyzed. The resulting taxonomy provides a structured framework for understanding the AI landscape in healthcare, facilitating evidence-based decision-making and guiding future research efforts toward the development of efficient and scalable AI approaches to meet current healthcare needs.<\/jats:p>","DOI":"10.1007\/s10462-024-10814-2","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T05:01:53Z","timestamp":1722229313000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Efficient artificial intelligence approaches for medical image processing in healthcare: comprehensive review, taxonomy, and analysis"],"prefix":"10.1007","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5770-594X","authenticated-orcid":false,"given":"Omar Abdullah Murshed Farhan","family":"Alnaggar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8620-2441","authenticated-orcid":false,"given":"Basavaraj N.","family":"Jagadale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0399-6339","authenticated-orcid":false,"given":"Mufeed Ahmed Naji","family":"Saif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2879-2751","authenticated-orcid":false,"given":"Osamah A. 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