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This study aimed to detect overlapped sensory processing alterations in a sample of children and adolescents diagnosed with both ASD and ADHD. A collection of 42 standard and 8 proposed machine learning classifiers, 22 feature selection methods and 19 unbalanced classification strategies were applied on the 6 standard question groups of the Sensory Profile-2 questionnaire. The relatively low performance achieved by state-of-the-art classifiers led us to propose the feature population sum classifier, a probabilistic method based on class and feature value populations, designed for datasets where features are discrete numeric answers to questions in a questionnaire. The proposed method achieves the best kappa and accuracy, 60% and 82.5%, respectively, reaching 68% and 86.5% combined with backward sequential feature selection, with false positive and negative rates below 15%. Since the SP2 questionnaire can be filled by parents for children from three years, our prediction can alert the clinicians with an early diagnosis in order to apply early interventions.<\/jats:p>","DOI":"10.1007\/s10489-024-05655-z","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T13:01:15Z","timestamp":1722258075000},"page":"9906-9923","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Population-based detection of children ASD\/ADHD comorbidity from atypical sensory processing"],"prefix":"10.1007","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5483-9424","authenticated-orcid":false,"given":"Manuel","family":"Fern\u00e1ndez-Delgado","sequence":"first","affiliation":[]},{"given":"Sara","family":"Cruz","sequence":"additional","affiliation":[]},{"given":"Eva","family":"Cernadas","sequence":"additional","affiliation":[]},{"given":"Heba","family":"Alateyat","sequence":"additional","affiliation":[]},{"given":"Mar\u00eda","family":"Tub\u00edo-Fungueiri\u00f1o","sequence":"additional","affiliation":[]},{"given":"Adriana","family":"Sampaio","sequence":"additional","affiliation":[]},{"given":"Angel","family":"Carracedo","sequence":"additional","affiliation":[]},{"given":"Montse","family":"Fern\u00e1ndez-Prieto","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2024,7,29]]},"reference":[{"key":"5655_CR1","doi-asserted-by":"publisher","unstructured":"Cleaton M, Kirby A (2018) Why do we find it so hard to calculate the burden of neurodevelopmental disorders? 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