{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:22:35Z","timestamp":1773447755405,"version":"3.50.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Dis Sci"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1007\/s10620-006-3201-4","type":"journal-article","created":{"date-parts":[[2006,4,13]],"date-time":"2006-04-13T20:45:15Z","timestamp":1144961115000},"page":"744-751","source":"Crossref","is-referenced-by-count":40,"title":["Identification of Dominant Bacteria in Feces and Colonic Mucosa from Healthy Spanish Adults by Culturing and by 16S rDNA Sequence Analysis"],"prefix":"10.1007","volume":"51","author":[{"given":"Susana","family":"Delgado","sequence":"first","affiliation":[]},{"given":"Adolfo","family":"Su\u00e1rez","sequence":"additional","affiliation":[]},{"given":"Baltasar","family":"Mayo","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"3201_CR1","first-page":"1","volume-title":"Human Colonic Bacteria: Role in Nutrition, Physiology, and Pathology","author":"PL Conway","year":"1995","unstructured":"Conway PL: Microbial ecology of the human large intestine. In Human Colonic Bacteria: Role in Nutrition, Physiology, and Pathology. GR Gibson, GT Macfarlane (eds). Boca Raton, FL, CRC Press, 1995, pp 1\u201324"},{"key":"3201_CR2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1023\/A:1002038308506","volume":"76","author":"GW Tannock","year":"1999","unstructured":"Tannock GW: Analysis of the intestinal microflora: a renaissance. Antonie van Leeuwenhoek 76:265\u2013278, 1999","journal-title":"Antonie van Leeuwenhoek"},{"key":"3201_CR3","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0958-6946(98)00074-0","volume":"8","author":"HS Gill","year":"1998","unstructured":"Gill HS: Stimulation of the immune system. Int Dairy J 8:535\u2013544, 1998","journal-title":"Int Dairy J"},{"key":"3201_CR4","doi-asserted-by":"crossref","first-page":"S147","DOI":"10.1079\/BJN19980108","volume":"80","author":"S Salminen","year":"1998","unstructured":"Salminen S, Bouley C, Boutron-Ruault MC, Cummings JH, Franck A, Gibson GR, Isolauri E, Moreau MC, Roberfroid M, Rowland I: Functional food science and gastrointestinal physiology and function. Br J Nutr 80:S147\u2013S171, 1998","journal-title":"Br J Nutr"},{"key":"3201_CR5","first-page":"103","volume":"54","author":"PW Parodi","year":"1999","unstructured":"Parodi PW: The role of intestinal bacteria in the causation and prevention of cancer: modulation by diet and probiotics. Aust J Dairy Technol 54:103\u2013121, 1999","journal-title":"Aust J Dairy Technol"},{"key":"3201_CR6","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1126\/science.1058709","volume":"292","author":"LV Hooper","year":"2001","unstructured":"Hooper LV, Gordon JI: Comensal host-bacteria relationships in the gut. Science 292:115\u20131118, 2001","journal-title":"Science"},{"key":"3201_CR7","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1093\/ajcn\/27.12.1450","volume":"27","author":"WEC Moore","year":"1974","unstructured":"Moore WEC, Holdeman LV: Special problems associated with their isolation and identification of intestinal bacteria in fecal flora studies. Am J Clin Nutr 27:1450\u20131455, 1974","journal-title":"Am J Clin Nutr"},{"key":"3201_CR8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1146\/annurev.mi.31.100177.000543","volume":"31","author":"DC Savage","year":"1977","unstructured":"Savage DC: Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 31:107\u2013133, 1977","journal-title":"Annu Rev Microbiol"},{"key":"3201_CR9","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1093\/ajcn\/27.12.1456","volume":"27","author":"SM Finegold","year":"1974","unstructured":"Finegold SM, Attebery HR, Sutter VL: Effect of diet on human fecal flora: comparison of Japanese and American diets. Am J Clin Nutr 27:1456\u20131469, 1974","journal-title":"Am J Clin Nutr"},{"key":"3201_CR10","first-page":"127","volume":"7","author":"C Noack-Loebel","year":"1983","unstructured":"Noack-Loebel C, K\u00fcster E, Rush V, Zimmermann K: Influence of different dietary regimen upon the composition of the human fecal flora. Prog Food Nutr Sci 7:127\u2013131, 1983","journal-title":"Prog Food Nutr Sci"},{"key":"3201_CR11","doi-asserted-by":"crossref","first-page":"4608","DOI":"10.1128\/AEM.62.12.4608-4613.1996","volume":"62","author":"AL McCartney","year":"1996","unstructured":"McCartney AL, Wang W, Tannock GW: Molecular analysis of the composition of the bifidobacterial and lactobacilli microflora of humans. Appl Environ Microbiol 62:4608\u20134613, 1996","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR12","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1128\/AEM.62.4.1242-1247.1996","volume":"62","author":"RF Wang","year":"1996","unstructured":"Wang RF, Cao WW, Cerniglia CE: PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples. Appl Environ Microbiol 62:1242\u20131247, 1996","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR13","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1128\/AEM.62.7.2273-2278.1996","volume":"62","author":"KH Wilson","year":"1996","unstructured":"Wilson KH, Blitchington RB: Human colonic biota studied by ribosomal DNA sequence analysis. Appl Environ Microbiol 62:2273\u20132278, 1996","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR14","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.1128\/AEM.64.9.3336-3345.1998","volume":"64","author":"AH Franks","year":"1998","unstructured":"Franks AH, Harmens HJM, Raangs GC, Jansen GJ, Schut F, Welling GW: Variation of bacterial populations in human feces measured by fluorescent in situhybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 64:3336\u20133345, 1998","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR15","doi-asserted-by":"crossref","first-page":"3854","DOI":"10.1128\/AEM.64.10.3854-3859.1998","volume":"64","author":"EG Zoetendal","year":"1998","unstructured":"Zoetendal EG, Akkermans ADL, de Vos WM: Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 64:3854\u20133863, 1998","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR16","doi-asserted-by":"crossref","first-page":"4799","DOI":"10.1128\/AEM.65.11.4799-4807.1999","volume":"65","author":"A Suau","year":"1999","unstructured":"Suau A, Bonnet R, Sutren M, Godon JJ, Gibson GR, Collins MD, Dor\u00e9 J: Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl Environ Microbiol 65:4799\u20134807, 1999","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR17","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1128\/AEM.66.5.2263-2266.2000","volume":"66","author":"A Sghir","year":"2000","unstructured":"Sghir A, Gramet G, Suau A, Rochet V, Pochart P, Dor\u00e9 J: Quantification of bacterial groups within human fecal flora by oligonucleotide probe hybridization. Appl Environ Microbiol 66:2263\u20132266, 2000","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR18","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1128\/AEM.31.3.359-375.1976","volume":"32","author":"LV Holdeman","year":"1976","unstructured":"Holdeman LV, Cato EP, Moore WEC: Human fecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress. Appl Environ Microbiol 32:359\u2013375, 1976","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR19","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1128\/AEM.61.9.3202-3207.1995","volume":"61","author":"WE Moore","year":"1995","unstructured":"Moore WE, Moore LH: Intestinal flora of populations that have a high risk of colon cancer. Appl Environ Microbiol 61:3202\u20133207, 1995","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR20","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1136\/gut.48.2.198","volume":"48","author":"MJ Hopkins","year":"2001","unstructured":"Hopkins MJ, Sharp R, Macfarlane GT: Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 48:198\u2013205, 2001","journal-title":"Gut"},{"key":"3201_CR21","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/089106001750462669","volume":"13","author":"EG Zoetendal","year":"2001","unstructured":"Zoetendal EG, Akkermans ADL, Akkermans van-Vliet WM, de Vos WM: The host genotype affects the bacterial community in the human gastrointestinal tract. Microb Ecol Health Dis 13:129\u2013134, 2001","journal-title":"Microb Ecol Health Dis"},{"key":"3201_CR22","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1348-0421.2002.tb02769.x","volume":"46","author":"H Hayashi","year":"2002","unstructured":"Hayashi H, Sakamoto M, Benno Y: Fecal microbial diversity in a strict vegetarian as determined by molecular analysis and cultivation. Microbiol Immunol 46:819\u2013831, 2002","journal-title":"Microbiol Immunol"},{"key":"3201_CR23","first-page":"335","volume":"15","author":"HJ Koornhof","year":"1976","unstructured":"Koornhof HJ, Richardson NJ, Wall MD, Moore WE: Fecal bacteria in South African rural blacks and other population groups. Isr J Med Sci 15:335\u2013340, 1976","journal-title":"Isr J Med Sci"},{"key":"3201_CR24","doi-asserted-by":"crossref","first-page":"S1035","DOI":"10.1093\/ajcn\/69.5.1035s","volume":"69","author":"RI Mackie","year":"1999","unstructured":"Mackie RI, Sgir A, Gaskins HR: Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr 69:S1035\u2013S1045, 1999","journal-title":"Am J Clin Nutr"},{"key":"3201_CR25","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0958-6946(98)00077-6","volume":"8","author":"S Salminen","year":"1998","unstructured":"Salminen S, Ouwehand AC, Isolauri E: Clinical applications of probiotic bacteria. Int Dairy J 8:563\u2013572, 1998","journal-title":"Int Dairy J"},{"key":"3201_CR26","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1128\/jb.173.7.2271-2277.1991","volume":"173","author":"JPW Young","year":"1991","unstructured":"Young JPW, Downer HL, Eardly BD: Phylogeny of the prototrophic Rhizobium strain BTAil by polymerase chain reaction-based sequencing of a 16S rRNA segment. J Bacteriol 173:2271\u20132277, 1991","journal-title":"J Bacteriol"},{"key":"3201_CR27","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","volume":"25","author":"SF Altschul","year":"1997","unstructured":"Altschul SF, Madden TL, Sch\u00e4ffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein databases search programs. Nucleic Acids Res 25:3389\u20133402, 1997","journal-title":"Nucleic Acids Res"},{"key":"3201_CR28","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1099\/00207713-44-4-846","volume":"44","author":"E Stackebrandt","year":"1994","unstructured":"Stackebrandt E, Goebel BM: Taxonomic note: a place for DNA\u2014DNA reassociation and 16S rRNA sequence analysis in the present species definition in bacteriology. Int J Syst Bacteriol 44:846\u2013849, 1994","journal-title":"Int J Syst Bacteriol"},{"key":"3201_CR29","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1046\/j.1365-2672.2003.02005.x","volume":"95","author":"X Wang","year":"2003","unstructured":"Wang X, Heazlewood SP, Krause DO, Florin THJ: Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis. J Appl Microbiol 95:508\u2013520, 2003","journal-title":"J Appl Microbiol"},{"key":"3201_CR30","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1099\/00207713-44-4-812","volume":"44","author":"MD Collins","year":"1994","unstructured":"Collins MD, Lawson PA, Willems A, C\u00f6rdoba JJ, Fern\u00e1ndez-Garaiz\u00e1bal J, Garc\u00eda P, Cai J, Hippe H, Farrow JA: The phylogeny of the genus Clostridium:proposal of five new genera and eleven new species combinations. Int J Syst Bacteriol 44:812\u2013826, 1994","journal-title":"Int J Syst Bacteriol"},{"key":"3201_CR31","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-1-4615-3522-5_4","volume-title":"The Lactic Acid Bacteria, Vol. 1. The Lactic Acid Bacteria in Health and Disease","author":"T Mitsuoka","year":"1992","unstructured":"Mitsuoka T: The human gastrointestinal tract. In The Lactic Acid Bacteria, Vol. 1. The Lactic Acid Bacteria in Health and Disease. BJB Wood (ed). London, Elsevier Applied Science, 1992, pp 69\u2013114"},{"key":"3201_CR32","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1348-0421.2002.tb02731.x","volume":"46","author":"H Hayashi","year":"2002","unstructured":"Hayashi H, Sakamoto M, Benno Y: Phylogenetic analysis of the human gut microbiota using 16S rDNA clone libraries and strictly anaerobic culture-based methods. Microbiol Immunol 46:535\u2013548, 2002","journal-title":"Microbiol Immunol"},{"key":"3201_CR33","volume-title":"Role of the Gut Bacteria in Human Toxicology and Pharmacology","author":"MJ Hill","year":"1995","unstructured":"Hill MJ: The normal gut bacterial flora. In Role of the Gut Bacteria in Human Toxicology and Pharmacology. MJ Hill (ed). London, Taylor Francis, 1995"},{"key":"3201_CR34","doi-asserted-by":"crossref","first-page":"5445","DOI":"10.1128\/AEM.68.11.5445-5451.2002","volume":"68","author":"T Matsuki","year":"2002","unstructured":"Matsuki T, Watanabe K, Fujimoto J, Miyamoto Y, Takada T, Matsumoto K, Oyaizu H, Tanaka R: Development of 16S rRNA-gene-targeted group-specific primers for the detection and identification of predominant bacteria in human feces. Appl Envion Microbiol 68:5445\u20135451, 2002","journal-title":"Appl Envion Microbiol"},{"key":"3201_CR35","first-page":"383","volume":"11","author":"A Trichopoulou","year":"1997","unstructured":"Trichopoulou A, Lagiou P: Healthy traditional Mediterranean diet: an expression of culture, history, and lifestyle. Nutr Rev 11:383\u2013389, 1997","journal-title":"Nutr Rev"},{"key":"3201_CR36","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1574-6941.2002.tb00904.x","volume":"39","author":"GL Hold","year":"2002","unstructured":"Hold GL, Pryde SE, Russell VJ, Furrie E, Flint HJ: Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis. FEMS Microbiol Ecol 39:33\u201339, 2002","journal-title":"FEMS Microbiol Ecol"},{"key":"3201_CR37","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1128\/AEM.61.8.3069-3075.1995","volume":"61","author":"PS Langendijk","year":"1995","unstructured":"Langendijk PS, Schut F, Jansen GJ, Raangs GC, Kamphuis GR, Wilkinson MHF, Welling GW: Quantitative fluorescence in situ hybridization of Bifidobacteriumspp. with genus-specific 16S rRNA-targeted probes and its application in fecal samples. Appl Environ Microbiol 61:3069\u20133075, 1995","journal-title":"Appl Environ Microbiol"},{"key":"3201_CR38","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1574-6968.2000.tb08945.x","volume":"183","author":"HJ Harmsen","year":"2000","unstructured":"Harmsen HJ, Gibson GR, Elfferich P, Raangs GC, Wideboer-Veloo AC, Argaiz A, Roberfroid MB, Welling GW: Comparison of viable cell counts and fluorescence in situ hybridization using specific rRNA-based probes for the quantification of human fecal bacteria. FEMS Microbiol Lett 183:125\u2013129, 2000","journal-title":"FEMS Microbiol Lett"},{"key":"3201_CR39","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1128\/AEM.68.7.3401-3407.2002","volume":"68","author":"EG Zoetendal","year":"2002","unstructured":"Zoetendal EG, von Wright A, Vilpponen-Salmela T, Ben-Amour K, Akkermans ADL, de Vos WM: Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from feces. Appl Environ Microbiol 68:3401\u20134407, 2002","journal-title":"Appl Environ Microbiol"}],"container-title":["Digestive Diseases and Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-006-3201-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10620-006-3201-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10620-006-3201-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,7]],"date-time":"2023-05-07T02:20:04Z","timestamp":1683426004000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10620-006-3201-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":39,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["3201"],"URL":"https:\/\/doi.org\/10.1007\/s10620-006-3201-4","relation":{},"ISSN":["0163-2116","1573-2568"],"issn-type":[{"value":"0163-2116","type":"print"},{"value":"1573-2568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}