{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:45:47Z","timestamp":1724287547175},"reference-count":90,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T00:00:00Z","timestamp":1288828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T00:00:00Z","timestamp":1288828800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Comput Neurosci"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1007\/s10827-010-0282-z","type":"journal-article","created":{"date-parts":[[2010,11,3]],"date-time":"2010-11-03T07:42:48Z","timestamp":1288770168000},"page":"633-658","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Determinants of synaptic integration and heterogeneity in rebound firing explored with data-driven models of deep cerebellar nucleus cells"],"prefix":"10.1007","volume":"30","author":[{"given":"Volker","family":"Steuber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan W.","family":"Schultheiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Angus","family":"Silver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"De Schutter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Jaeger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,11,4]]},"reference":[{"key":"282_CR1","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1371\/journal.pcbi.0020094","volume":"2","author":"P Achard","year":"2006","unstructured":"Achard, P., & De Schutter, E. (2006). Complex parameter landscape for a complex neuron model. PLoS Computational Biology, 2, 794\u2013804.","journal-title":"PLoS Computational Biology"},{"key":"282_CR2","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1152\/jn.1999.82.4.1697","volume":"82","author":"CD Aizenman","year":"1999","unstructured":"Aizenman, C. D., & Linden, D. J. (1999). Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum. Journal of Neurophysiology, 82, 1697\u20131709.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR3","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1038\/72049","volume":"3","author":"CD Aizenman","year":"2000","unstructured":"Aizenman, C. D., & Linden, D. J. (2000). Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons. Nature Neuroscience, 3, 109\u2013111.","journal-title":"Nature Neuroscience"},{"key":"282_CR4","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.1113\/jphysiol.2007.148197","volume":"586","author":"K Alvina","year":"2008","unstructured":"Alvina, K., & Khodakhah, K. (2008). Selective regulation of spontaneous activity of neurons of the deep cerebellar nuclei by N-type calcium channels in juvenile rats. Journal of Physiology-London, 586, 2523\u20132538.","journal-title":"Journal of Physiology-London"},{"key":"282_CR5","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1038\/nn.2195","volume":"11","author":"K Alvina","year":"2008","unstructured":"Alvina, K., Walter, J. T., Kohn, A., Ellis-Davies, G., & Khodakhah, K. (2008). Questioning the role of rebound firing in the cerebellum. Nature Neuroscience, 11, 1256\u20131258.","journal-title":"Nature Neuroscience"},{"key":"282_CR6","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1523\/JNEUROSCI.13-02-00660.1993","volume":"13","author":"C Alzheimer","year":"1993","unstructured":"Alzheimer, C., Schwindt, P. C., & Crill, W. E. (1993). Modal gating of Na+ channels as a mechanism of persistent Na+ current in pyramidal neurons from rat and cat sensorimotor cortex. The Journal of Neuroscience, 13, 660\u2013673.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/jn.2001.85.1.323","volume":"85","author":"D Anchisi","year":"2001","unstructured":"Anchisi, D., Scelfo, B., & Tempia, F. (2001). Postsynaptic currents in deep cerebellar nuclei. Journal of Neurophysiology, 85, 323\u2013331.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR8","doi-asserted-by":"publisher","first-page":"3460","DOI":"10.1152\/jn.00588.2005","volume":"95","author":"P Aracri","year":"2006","unstructured":"Aracri, P., Colombo, E., Mantegazza, M., Scalmani, P., Curia, G., Avanzini, G., et al. (2006). Layer-specific properties of the persistent sodium current in sensorimotor cortex. Journal of Neurophysiology, 95, 3460\u20133468.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR9","doi-asserted-by":"publisher","first-page":"11720","DOI":"10.1523\/JNEUROSCI.2887-06.2006","volume":"26","author":"TG Banke","year":"2006","unstructured":"Banke, T. G., & McBain, C. J. (2006). GABAergic input onto CA3 hippocampal interneurons remains shunting throughout development. The Journal of Neuroscience, 26, 11720\u201311725.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR10","doi-asserted-by":"crossref","first-page":"6394","DOI":"10.1523\/JNEUROSCI.19-15-06394.1999","volume":"19","author":"G Baranauskas","year":"1999","unstructured":"Baranauskas, G., Tkatch, T., & Surmeier, D. J. (1999). Delayed rectifier currents in rat globus pallidus neurons are attributable to Kv2.1 and Kv3.1\/3.2K(+) channels. The Journal of Neuroscience, 19, 6394\u20136404.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR11","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1038\/nn1019","volume":"6","author":"G Baranauskas","year":"2003","unstructured":"Baranauskas, G., Tkatch, T., Nagata, K., Yeh, J. Z., & Surmeier, D. J. (2003). Kv3.4 subunits enhance the repolarizing efficiency of Kv3.1 channels in fast-spiking neurons. Nature Neuroscience, 6, 258\u2013266.","journal-title":"Nature Neuroscience"},{"key":"282_CR12","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/S0079-6123(08)63381-6","volume":"114","author":"JM Bower","year":"1997","unstructured":"Bower, J. M. (1997). Is the cerebellum sensory for motor\u2019s sake, or motor for sensory\u2019s sake: the view from the whiskers of a rat? Progress in Brain Research, 114, 483\u2013516.","journal-title":"Progress in Brain Research"},{"key":"282_CR13","volume-title":"The book of Genesis","author":"JM Bower","year":"1997","unstructured":"Bower, J. M., & Beeman, D. (1997). The book of Genesis (2nd ed.). New York: Springer.","edition":"2"},{"key":"282_CR14","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1152\/jn.1994.71.6.2562","volume":"71","author":"AM Brown","year":"1994","unstructured":"Brown, A. M., Schwindt, P. C., & Crill, W. E. (1994). Different voltage-dependence of transient and persistent Na+ currents is compatible with modal-gating hypothesis for sodium-channels. Journal of Neurophysiology, 71, 2562\u20132565.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0925-2312(02)00357-0","volume":"44\u201346","author":"AM Castelfranco","year":"2002","unstructured":"Castelfranco, A. M., & Hartline, D. K. (2002). Simulations of space-clamp errors in estimating parameters of voltage-gated conductances localized at different electrotonic distances. Neurocomputing, 44\u201346, 75\u201380.","journal-title":"Neurocomputing"},{"key":"282_CR16","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1017\/S0021878200007172","volume":"198","author":"S \u00c7avdar","year":"2001","unstructured":"\u00c7avdar, S., San, T., Aker, R., Sehirli, \u00dc., & Onat, F. (2001). Cerebellar connections to the dorsomedial and posterior nuclei of the hypothalamus in the rat. Journal of Anatomy, 198, 37\u201345.","journal-title":"Journal of Anatomy"},{"key":"282_CR17","doi-asserted-by":"crossref","unstructured":"Chan-Palay, V. (1977). Cerebellar dentate nucleus. Springer-Verlag.","DOI":"10.1007\/978-3-642-66498-4"},{"key":"282_CR18","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1037\/0735-7044.117.6.1211","volume":"117","author":"JS Choi","year":"2003","unstructured":"Choi, J. S., & Moore, J. W. (2003). Cerebellar neuronal activity expresses the complex topography of conditioned eyeblink responses. Behavioral Neuroscience, 117, 1211\u20131219.","journal-title":"Behavioral Neuroscience"},{"key":"282_CR19","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/0168-0102(87)90027-7","volume":"5","author":"H Daniel","year":"1987","unstructured":"Daniel, H., Billard, J. M., Angaut, P., & Batini, C. (1987). The interposito-rubrospinal system. Anatomical tracing of a motor control pathway in the rat. Neuroscience Research, 5, 87\u2013112.","journal-title":"Neuroscience Research"},{"key":"282_CR20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1152\/jn.1994.71.1.401","volume":"71","author":"E De Schutter","year":"1994","unstructured":"De Schutter, E., & Bower, J. M. (1994). An active membrane model of the cerebellar Purkinje cell. II. Simulation of synaptic responses. Journal of Neurophysiology, 71, 401\u2013419.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR21","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1523\/JNEUROSCI.18-10-03574.1998","volume":"18","author":"A Destexhe","year":"1998","unstructured":"Destexhe, A., Neubig, M., Ulrich, D., & Huguenard, J. (1998). Dendritic low-threshold calcium currents in thalamic relay cells. The Journal of Neuroscience, 18, 3574\u20133588.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR22","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1038\/nrn1198","volume":"4","author":"A Destexhe","year":"2003","unstructured":"Destexhe, A., Rudolph, M., & Par\u00e9, D. (2003). The high-conductance state of neocortical neurons in vivo. Nature Reviews Neuroscience, 4, 739\u2013751.","journal-title":"Nature Reviews Neuroscience"},{"key":"282_CR23","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/BF01673258","volume":"184","author":"BJ Fredette","year":"1991","unstructured":"Fredette, B. J., & Mugnaini, E. (1991). The GABAergic cerebello-olivary projection in the rat. Anatomy and Embryology (Berlin), 184, 225\u2013243.","journal-title":"Anatomy and Embryology (Berlin)"},{"key":"282_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/0165-3806(85)90230-5","volume":"19","author":"R Gardette","year":"1985","unstructured":"Gardette, R., Debono, M., Dupont, J.-L., & Crepel, F. (1985a). Electrophysiological studies on the postnatal development of intracerebellar nuclei neurons in rat cerebellar slices maintained in vitro. I. Postsynaptic potentials. Developmental Brain Research, 19, 47\u201355.","journal-title":"Developmental Brain Research"},{"key":"282_CR25","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/0165-3806(85)90091-4","volume":"20","author":"R Gardette","year":"1985","unstructured":"Gardette, R., Debono, M., Dupont, J.-L., & Crepel, F. (1985b). Electrophysiological studies on the postnatal development of intracerebellar nuclei neurons in rat cerebellar slices maintained in vitro. II. Membrane conductances. Developmental Brain Research, 20, 97\u2013106.","journal-title":"Developmental Brain Research"},{"key":"282_CR26","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1152\/jn.1975.38.3.627","volume":"38","author":"EP Gardner","year":"1975","unstructured":"Gardner, E. P., & Fuchs, A. F. (1975). Single-unit responses to natural vestibular stimuli and eye movements in deep cerebellar nuclei of the alert rhesus monkey. Journal of Neurophysiology, 38, 627\u2013649.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR27","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1523\/JNEUROSCI.20-08-03006.2000","volume":"20","author":"V Gauck","year":"2000","unstructured":"Gauck, V., & Jaeger, D. (2000). The control of rate and timing of spikes in the deep cerebellar nuclei by inhibition. The Journal of Neuroscience, 20, 3006\u20133016.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR28","doi-asserted-by":"crossref","first-page":"8109","DOI":"10.1523\/JNEUROSCI.23-22-08109.2003","volume":"23","author":"V Gauck","year":"2003","unstructured":"Gauck, V., & Jaeger, D. (2003). The contribution of NMDA and AMPA conductances to the control of spiking in neurons of the deep cerebellar nuclei. The Journal of Neuroscience, 23, 8109\u20138118.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR29","doi-asserted-by":"crossref","first-page":"RC158","DOI":"10.1523\/JNEUROSCI.21-15-j0004.2001","volume":"21","author":"V Gauck","year":"2001","unstructured":"Gauck, V., Thomann, M., Jaeger, D., & Borst, A. (2001). Spatial distribution of low- and high-voltage-activated calcium currents in neurons of the deep cerebellar nuclei. The Journal of Neuroscience, 21, RC158.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR30","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1139\/y96-039","volume":"74","author":"AR Gibson","year":"1996","unstructured":"Gibson, A. R., Horn, K. M., Stein, J. F., & VanKan, P. L. E. (1996). Activity of interpositus neurons during a visually guided reach. Canadian Journal of Physiology and Pharmacology, 74, 499\u2013512.","journal-title":"Canadian Journal of Physiology and Pharmacology"},{"key":"282_CR31","doi-asserted-by":"crossref","unstructured":"Gleeson, P., Crook, S., Cannon, R. C., Hines, M. L., Billings, G. O., Farinella, M., Morse, T. M., Davison, A. P., Ray, S., Bhalla, U. S., Barnes, S. R., Dimitrova, Y. D., & Silver, R. A. (2010). NeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detail. PLoS Computational Biology 6, e1000815.","DOI":"10.1371\/journal.pcbi.1000815"},{"key":"282_CR32","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1152\/jn.00115.2002","volume":"89","author":"HP Goodkin","year":"2003","unstructured":"Goodkin, H. P., & Thach, W. T. (2003). Cerebellar control of constrained and unconstrained movements. II. EMG and nuclear activity. Journal of Neurophysiology, 89, 896\u2013908.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR33","doi-asserted-by":"publisher","first-page":"7476","DOI":"10.1523\/JNEUROSCI.4198-07.2008","volume":"28","author":"C Gunay","year":"2008","unstructured":"Gunay, C., Edgerton, J. R., & Jaeger, D. (2008). Channel density distributions explain spiking variability in the globus pallidus: a combined physiology and computer simulation database approach. The Journal of Neuroscience, 28, 7476\u20137491.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR34","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/BF00235785","volume":"45","author":"K Hepp","year":"1982","unstructured":"Hepp, K., Henn, V., & Jaeger, J. (1982). Eye movement related neurons in the cerebellar nuclei of the alert monkey. Experimental Brain Research, 45, 253\u2013264.","journal-title":"Experimental Brain Research"},{"key":"282_CR35","volume-title":"Ion channels of excitable membranes","author":"B Hille","year":"2001","unstructured":"Hille, B. (2001). Ion channels of excitable membranes (3rd ed.). Sunderland: Sinauer.","edition":"3"},{"key":"282_CR36","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1017\/S0140525X00081474","volume":"19","author":"JC Houk","year":"1996","unstructured":"Houk, J. C., Buckingham, J. T., & Barto, A. G. (1996). Models of the cerebellum and motor learning. The Behavioral and Brain Sciences, 19, 368\u2013383.","journal-title":"The Behavioral and Brain Sciences"},{"key":"282_CR37","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1038\/nrn2332","volume":"9","author":"M Ito","year":"2008","unstructured":"Ito, M. (2008). Opinion\u2014control of mental activities by internal models in the cerebellum. Nature Reviews. Neuroscience, 9, 304\u2013313.","journal-title":"Nature Reviews. Neuroscience"},{"key":"282_CR38","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1162\/jocn.1989.1.2.136","volume":"1","author":"RB Ivry","year":"1989","unstructured":"Ivry, R. B., & Keele, S. W. (1989). Timing functions of the cerebellum. Journal of Cognitive Neuroscience, 1, 136\u2013152.","journal-title":"Journal of Cognitive Neuroscience"},{"key":"282_CR39","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1023\/A:1023217111784","volume":"14","author":"D Jaeger","year":"2003","unstructured":"Jaeger, D. (2003). No parallel fiber volleys in the cerebellar cortex: evidence from cross-correlation analysis between Purkinje cells in a computer model and in recordings from anesthetized rats. Journal of Computational Neuroscience, 14, 311\u2013327.","journal-title":"Journal of Computational Neuroscience"},{"key":"282_CR40","doi-asserted-by":"crossref","first-page":"6090","DOI":"10.1523\/JNEUROSCI.19-14-06090.1999","volume":"19","author":"D Jaeger","year":"1999","unstructured":"Jaeger, D., & Bower, J. M. (1999). Synaptic control of spiking in cerebellar Purkinje cells: dynamic current clamp based on model conductances. The Journal of Neuroscience, 19, 6090\u20136101.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR41","doi-asserted-by":"publisher","first-page":"3305","DOI":"10.1523\/JNEUROSCI.4866-06.2007","volume":"27","author":"MM Jagodic","year":"2007","unstructured":"Jagodic, M. M., Pathirathna, S., Nelson, M. T., Mancuso, S., Joksovic, P. M., Rosenberg, E. R., et al. (2007). Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons. The Journal of Neuroscience, 27, 3305\u20133316.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR42","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1113\/jphysiol.1986.sp016001","volume":"372","author":"H Jahnsen","year":"1986","unstructured":"Jahnsen, H. (1986a). Electrophysiological characteristics of neurones in the guinea-pig deep cerebellar nuclei in vitro. Journal de Physiologie, 372, 129\u2013147.","journal-title":"Journal de Physiologie"},{"key":"282_CR43","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1113\/jphysiol.1986.sp016002","volume":"372","author":"H Jahnsen","year":"1986","unstructured":"Jahnsen, H. (1986b). Extracellular activation and membrane conductances of neurones in the guinea-pig deep cerebellar nuclei in vitro. Journal de Physiologie, 372, 149\u2013168.","journal-title":"Journal de Physiologie"},{"key":"282_CR44","doi-asserted-by":"publisher","first-page":"3137","DOI":"10.1152\/jn.00021.2003","volume":"90","author":"JF Kleine","year":"2003","unstructured":"Kleine, J. F., Guan, Y., & Buttner, U. (2003). Saccade-related neurons in the primate fastigial nucleus: what do they encode? Journal of Neurophysiology, 90, 3137\u20133154.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR45","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1523\/JNEUROSCI.19-07-02728.1999","volume":"19","author":"EJ Lang","year":"1999","unstructured":"Lang, E. J., Sugihara, I., Welsh, J. P., & Llinas, R. (1999). Patterns of spontaneous Purkinje cell complex spike activity in the awake rat. The Journal of Neuroscience, 19, 2728\u20132739.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR46","doi-asserted-by":"publisher","first-page":"29777","DOI":"10.1074\/jbc.M705053200","volume":"282","author":"HHC Lee","year":"2007","unstructured":"Lee, H. H. C., Walker, J. A., Williams, J. R., Goodier, R. J., Payne, J. A., & Moss, S. J. (2007). Direct protein kinase C-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter KCC2. The Journal of Biological Chemistry, 282, 29777\u201329784.","journal-title":"The Journal of Biological Chemistry"},{"key":"282_CR47","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1113\/jphysiol.1988.sp017288","volume":"404","author":"R Llinas","year":"1988","unstructured":"Llinas, R., & Muhlethaler, M. (1988). Electrophysiology of guinea-pig cerebellar nuclear cells in the in vitro brain stem-cerebellar preparation. Journal de Physiologie, 404, 241\u2013258.","journal-title":"Journal de Physiologie"},{"key":"282_CR48","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/BF00247521","volume":"71","author":"WA MacKay","year":"1988","unstructured":"MacKay, W. A. (1988). Cerebellar nuclear activity in relation to simple movements. Experimental Brain Research, 71, 47\u201358.","journal-title":"Experimental Brain Research"},{"key":"282_CR49","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1085\/jgp.114.4.491","volume":"114","author":"J Magistretti","year":"1999","unstructured":"Magistretti, J., & Alonso, A. (1999). Biophysical properties and slow voltage-dependent inactivation of a sustained sodium current in entorhinal cortex layer-II principal neurons\u2014a whole-cell and single-channel study. The Journal of General Physiology, 114, 491\u2013509.","journal-title":"The Journal of General Physiology"},{"key":"282_CR50","doi-asserted-by":"crossref","first-page":"5516","DOI":"10.1523\/JNEUROSCI.20-14-05516.2000","volume":"20","author":"JF Medina","year":"2000","unstructured":"Medina, J. F., Garcia, K. S., Nores, W. L., Taylor, N. M., & Mauk, M. D. (2000). Timing mechanisms in the cerebellum: testing predictions of a large-scale computer simulation. The Journal of Neuroscience, 20, 5516\u20135525.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR51","doi-asserted-by":"publisher","first-page":"5555","DOI":"10.1073\/pnas.0601261103","volume":"103","author":"ML Molineux","year":"2006","unstructured":"Molineux, M. L., McRory, J. E., McKay, B. E., Hamid, J., Mehaffey, W. H., Rehak, R., et al. (2006). Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons. Proceedings of the National Academy of Sciences of the United States of America, 103, 5555\u20135560.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"282_CR52","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1152\/jn.1994.71.1.420","volume":"71","author":"R Muri","year":"1994","unstructured":"Muri, R., & Knopfel, T. (1994). Activity induced elevations of intracellular calcium concentration in neurons of the deep cerebellar nuclei. Journal of Neurophysiology, 71, 420\u2013428.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR53","unstructured":"Nejad, R. T., Molineux, M. L., Mehaffey, W. H., & Turner, R. W. (2007). Transient and weak bursting deep cerebellar neurons exhibit differential coding properties for membrane hyperpolarizations. Program No. 409.12. Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience Online."},{"key":"282_CR54","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1152\/jn.00508.2003","volume":"92","author":"T Otsuka","year":"2004","unstructured":"Otsuka, T., Abe, T., Tsukagawa, T., & Song, W. J. (2004). Conductance-based model of the voltage-dependent generation of a plateau potential in subthalamic neurons. Journal of Neurophysiology, 92, 255\u2013264.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR55","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/BF00237096","volume":"28","author":"M Palkovits","year":"1977","unstructured":"Palkovits, M., Mezey, E., Hamori, J., & Szentagothai, J. (1977). Quantitative histological analysis of the cerebellar nuclei in the cat. I. Numerical data on cells and synapses. Experimental Brain Research, 28, 189\u2013209.","journal-title":"Experimental Brain Research"},{"key":"282_CR56","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1146\/annurev.ph.58.030196.001503","volume":"58","author":"HC Pape","year":"1996","unstructured":"Pape, H. C. (1996). Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annual Review of Physiology, 58, 299\u2013327.","journal-title":"Annual Review of Physiology"},{"key":"282_CR57","first-page":"183","volume-title":"Advances in processing and pattern analysis of biological signals","author":"MG Paulin","year":"1995","unstructured":"Paulin, M. G. (1995). System identification of spiking sensory neurons using realistically constrained nonlinear time series models. In I. Gath & G. Inbar (Eds.), Advances in processing and pattern analysis of biological signals (pp. 183\u2013194). Plenum: New York."},{"key":"282_CR58","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s12311-009-0153-1","volume":"9","author":"CM Pedroarena","year":"2010","unstructured":"Pedroarena, C. M. (2010). Mechanisms supporting transfer of inhibitory signals into the spike output of spontaneously firing cerebellar nuclear neurons in vitro. Cerebellum, 9, 67\u201376.","journal-title":"Cerebellum"},{"key":"282_CR59","doi-asserted-by":"publisher","first-page":"3998","DOI":"10.1152\/jn.00641.2003","volume":"90","author":"AA Prinz","year":"2003","unstructured":"Prinz, A. A., Billimoria, C. P., & Marder, E. (2003). Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons. Journal of Neurophysiology, 90, 3998\u20134015.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR60","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.neuron.2006.05.021","volume":"51","author":"JR Pugh","year":"2006","unstructured":"Pugh, J. R., & Raman, I. M. (2006). Potentiation of mossy fiber EPSCs in the cerebellar nuclei by NMDA receptor activation followed by postinhibitory rebound current. Neuron, 51, 113\u2013123.","journal-title":"Neuron"},{"key":"282_CR61","doi-asserted-by":"publisher","first-page":"10549","DOI":"10.1523\/JNEUROSCI.2061-08.2008","volume":"28","author":"JR Pugh","year":"2008","unstructured":"Pugh, J. R., & Raman, I. M. (2008). Mechanisms of potentiation of mossy fiber EPSCs in the cerebellar nuclei by coincident synaptic excitation and inhibition. The Journal of Neuroscience, 28, 10549\u201310560.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR62","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1152\/jn.00703.2004","volume":"93","author":"LK Purvis","year":"2005","unstructured":"Purvis, L. K., & Butera, R. J. (2005). Ionic current model of a hypoglossal motoneuron. Journal of Neurophysiology, 93, 723\u2013733.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR63","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1152\/jn.1999.82.2.999","volume":"82","author":"C Quaia","year":"1999","unstructured":"Quaia, C., Lefevre, P., & Optican, L. M. (1999). Model of the control of saccades by superior colliculus and cerebellum. Journal of Neurophysiology, 82, 999\u20131018.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR64","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/0014-4886(59)90046-9","volume":"1","author":"W Rall","year":"1959","unstructured":"Rall, W. (1959). Branching dendritic trees and motoneuron membrane resistivity. Experimental Neurology, 1, 491\u2013527.","journal-title":"Experimental Neurology"},{"key":"282_CR65","doi-asserted-by":"crossref","first-page":"9004","DOI":"10.1523\/JNEUROSCI.20-24-09004.2000","volume":"20","author":"IM Raman","year":"2000","unstructured":"Raman, I. M., Gustafson, A. E., & Padgett, D. (2000). Ionic currents and spontaneous firing in neurons isolated from the cerebellar nuclei. The Journal of Neuroscience, 20, 9004\u20139016.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR66","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/16697","volume":"397","author":"C Rivera","year":"1999","unstructured":"Rivera, C., Voipio, J., Payne, J. A., Ruusuvuori, E., Lahtinen, H., Lamsa, K., et al. (1999). The K+\/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature, 397, 251\u2013255.","journal-title":"Nature"},{"key":"282_CR67","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1152\/jn.1976.39.5.954","volume":"39","author":"DA Robinson","year":"1976","unstructured":"Robinson, D. A. (1976). Adaptive gain control of vestibuloocular reflex by cerebellum. Journal of Neurophysiology, 39, 954\u2013969.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR68","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1038\/nature07604","volume":"457","author":"JS Rothman","year":"2009","unstructured":"Rothman, J. S., Cathala, L., Steuber, V., & Silver, R. A. (2009). Synaptic depression enables neuronal gain control. Nature, 457, 1015\u2013U1016.","journal-title":"Nature"},{"key":"282_CR69","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1152\/jn.00285.2005","volume":"94","author":"NC Rowland","year":"2005","unstructured":"Rowland, N. C., & Jaeger, D. (2005). Coding of tactile response properties in the rat deep cerebellar nuclei. Journal of Neurophysiology, 94, 1236\u20131251.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR70","unstructured":"Sangrey, T. D., & Jaeger, D. (2005). Currents underlying hyperpolarization-induced rebound spiking in deep cerebellar nuclei neurons. In Program No. 179.10. 2005 Abstract Viewer\/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online."},{"key":"282_CR71","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1001\/archneur.1991.00530230086029","volume":"48","author":"JD Schmahmann","year":"1991","unstructured":"Schmahmann, J. D. (1991). An emerging concept: the cerebellar contribution to higher function. Archives of Neurology, 48, 1178\u20131187.","journal-title":"Archives of Neurology"},{"key":"282_CR72","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.brainresrev.2003.10.004","volume":"44","author":"N Schweighofer","year":"2004","unstructured":"Schweighofer, N., Doya, K., & Kuroda, S. (2004). Cerebellar aminergic neuromodulation: towards a functional understanding. Brain Research. Brain Research Reviews, 44, 103\u2013116.","journal-title":"Brain Research. Brain Research Reviews"},{"key":"282_CR73","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1162\/neco.2007.19.4.910","volume":"19","author":"AK Seth","year":"2007","unstructured":"Seth, A. K., & Edelman, G. M. (2007). Distinguishing causal interactions in neural populations. Neural Computation, 19, 910\u2013933.","journal-title":"Neural Computation"},{"key":"282_CR74","doi-asserted-by":"crossref","first-page":"3006","DOI":"10.1152\/jn.1999.82.6.3006","volume":"82","author":"GYY Shen","year":"1999","unstructured":"Shen, G. Y. Y., Chen, W. R., Midtgaard, J., Shepherd, G. M., & Hines, M. L. (1999). Computational analysis of action potential initiation in mitral cell soma and dendrites based on dual patch recordings. Journal of Neurophysiology, 82, 3006\u20133020.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR75","doi-asserted-by":"publisher","first-page":"e485","DOI":"10.1371\/journal.pone.0000485","volume":"2","author":"S Shin","year":"2007","unstructured":"Shin, S., Hoebeek, F. E., Schonewille, M., De Zeeuw, C. I., Aertsen, A., & De Schutter, E. (2007). Regular patterns in cerebellar Purkinje cell simple spike train. PLoS ONE, 2, e485.","journal-title":"PLoS ONE"},{"key":"282_CR76","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1038\/28848","volume":"394","author":"EA Stern","year":"1998","unstructured":"Stern, E. A., Jaeger, D., & Wilson, C. J. (1998). Membrane potential synchrony of simultaneously recorded striatal spiny neurons in vivo. Nature, 394, 475\u2013478.","journal-title":"Nature"},{"key":"282_CR77","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.neucom.2004.01.095","volume":"58\u201360","author":"V Steuber","year":"2004","unstructured":"Steuber, V., De Schutter, E., & Jaeger, D. (2004). Passive models of neurons in the deep cerebellar nuclei: the effect of reconstruction errors. Neurocomputing, 58\u201360, 563\u2013568.","journal-title":"Neurocomputing"},{"key":"282_CR78","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.neuron.2007.03.015","volume":"54","author":"V Steuber","year":"2007","unstructured":"Steuber, V., Mittmann, W., Hoebeek, F. E., Silver, R. A., De Zeeuw, C. I., Hausser, M., et al. (2007). Cerebellar LTD and pattern recognition by Purkinje cells. Neuron, 54, 121\u2013136.","journal-title":"Neuron"},{"key":"282_CR79","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1002\/cne.10443","volume":"455","author":"F Sultan","year":"2003","unstructured":"Sultan, F., Czubayko, U., & Thier, P. (2003). Morphological classification of the rat lateral cerebellar nuclear neurons by principal component analysis. The Journal of Comparative Neurology, 455, 139\u2013155.","journal-title":"The Journal of Comparative Neurology"},{"key":"282_CR80","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1111\/j.1460-9568.2006.04880.x","volume":"24","author":"R Surges","year":"2006","unstructured":"Surges, R., Brewster, A. L., Bender, R. A., Beck, H., Feuerstein, T. J., & Baram, T. Z. (2006). Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampus. The European Journal of Neuroscience, 24, 94\u2013104.","journal-title":"The European Journal of Neuroscience"},{"key":"282_CR81","doi-asserted-by":"publisher","first-page":"149","DOI":"10.4161\/chan.3.3.8872","volume":"3","author":"R Tadayonnejad","year":"2009","unstructured":"Tadayonnejad, R., Mehaffey, W. H., Anderson, D., & Turner, R. W. (2009). Reliability of triggering postinhibitory rebound bursts in deep cerebellar neurons. Channels, 3, 149\u2013155.","journal-title":"Channels"},{"key":"282_CR82","doi-asserted-by":"publisher","first-page":"5573","DOI":"10.1523\/JNEUROSCI.4438-08.2009","volume":"29","author":"AL Taylor","year":"2009","unstructured":"Taylor, A. L., Goaillard, J.-M., & Marder, E. (2009). How multiple conductances determine electrophysiological properties in a multicompartment model. The Journal of Neuroscience, 29, 5573\u20135586.","journal-title":"The Journal of Neuroscience"},{"key":"282_CR83","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0896-6273(03)00802-X","volume":"41","author":"P Telgkamp","year":"2004","unstructured":"Telgkamp, P., Padgett, D. E., Ledoux, V. A., Woolley, C. S., & Raman, I. M. (2004). Maintenance of high-frequency transmission at purkinje to cerebellar nuclear synapses by spillover from boutons with multiple release sites. Neuron, 41, 113\u2013126.","journal-title":"Neuron"},{"key":"282_CR84","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1152\/jn.2001.86.6.2690","volume":"86","author":"D Timmann","year":"2001","unstructured":"Timmann, D., Citron, R., Watts, S., & Hore, J. (2001). Increased variability in finger position occurs throughout overarm throws made by cerebellar and unskilled subjects. Journal of Neurophysiology, 86, 2690\u20132702.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR85","doi-asserted-by":"publisher","first-page":"1963","DOI":"10.1124\/mol.105.020842","volume":"69","author":"A Traboulsie","year":"2006","unstructured":"Traboulsie, A., Chemin, J., Kupfer, E., Nargeot, J., & Lory, P. (2006). T-type calcium channels are inhibited by fluoxetine and its metabolite norfluoxetine. Molecular Pharmacology, 69, 1963\u20131968.","journal-title":"Molecular Pharmacology"},{"key":"282_CR86","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1152\/jn.00974.2006","volume":"97","author":"M Uusisaari","year":"2007","unstructured":"Uusisaari, M., Obata, K., & Knopfel, T. (2007). Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei. Journal of Neurophysiology, 97, 901\u2013911.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR87","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1152\/jn.1993.69.1.57","volume":"69","author":"PL van Kan","year":"1993","unstructured":"van Kan, P. L., Houk, J. C., & Gibson, A. R. (1993). Output organization of intermediate cerebellum of the monkey. Journal of Neurophysiology, 69, 57\u201373.","journal-title":"Journal of Neurophysiology"},{"key":"282_CR88","doi-asserted-by":"crossref","unstructured":"Wetmore, D. Z., Mukamel, E. A., & Schnitzer, M. (2007). Lock-and-key mechanisms of cerebellar memory recall based on rebound currents. J Neurophysiol. epub in press.","DOI":"10.1152\/jn.00344.2007"},{"key":"282_CR89","doi-asserted-by":"publisher","first-page":"9826","DOI":"10.1523\/JNEUROSCI.2069-09.2009","volume":"29","author":"N Zheng","year":"2009","unstructured":"Zheng, N., & Raman, I. M. (2009). Ca currents activated by spontaneous firing and synaptic disinhibition in neurons of the cerebellar nuclei. Journal of Neuroscience, 29, 9826\u20139838.","journal-title":"Journal of Neuroscience"},{"key":"282_CR90","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1152\/jn.00616.2004","volume":"93","author":"L Zhu","year":"2005","unstructured":"Zhu, L., Lovinger, D., & Delpire, E. (2005). Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride. Journal of Neurophysiology, 93, 1557\u20131568.","journal-title":"Journal of Neurophysiology"}],"container-title":["Journal of Computational Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10827-010-0282-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10827-010-0282-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10827-010-0282-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10827-010-0282-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T21:28:09Z","timestamp":1630445289000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10827-010-0282-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,4]]},"references-count":90,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["282"],"URL":"https:\/\/doi.org\/10.1007\/s10827-010-0282-z","relation":{},"ISSN":["0929-5313","1573-6873"],"issn-type":[{"value":"0929-5313","type":"print"},{"value":"1573-6873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,4]]},"assertion":[{"value":"22 September 2009","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2010","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2010","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2010","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}