{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:39:43Z","timestamp":1774139983107,"version":"3.50.1"},"reference-count":77,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:00:00Z","timestamp":1513036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000006","name":"Office of Naval Research","doi-asserted-by":"publisher","award":["N000141310672"],"award-info":[{"award-number":["N000141310672"]}],"id":[{"id":"10.13039\/100000006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["MH099645"],"award-info":[{"award-number":["MH099645"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-136969"],"award-info":[{"award-number":["MOP-136969"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-136967"],"award-info":[{"award-number":["MOP-136967"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Comput Neurosci"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s10827-017-0663-7","type":"journal-article","created":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T00:21:51Z","timestamp":1513038111000},"page":"1-24","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["New class of reduced computationally efficient neuronal models for large-scale simulations of brain dynamics"],"prefix":"10.1007","volume":"44","author":[{"given":"Maxim","family":"Komarov","sequence":"first","affiliation":[]},{"given":"Giri","family":"Krishnan","sequence":"additional","affiliation":[]},{"given":"Sylvain","family":"Chauvette","sequence":"additional","affiliation":[]},{"given":"Nikolai","family":"Rulkov","sequence":"additional","affiliation":[]},{"given":"Igor","family":"Timofeev","sequence":"additional","affiliation":[]},{"given":"Maxim","family":"Bazhenov","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2017,12,12]]},"reference":[{"key":"663_CR1","doi-asserted-by":"crossref","unstructured":"Achermann, P., & Borbely, A. A. (1997). Low-frequency (<1 Hz) oscillations in the human sleep electroencephalogram. Neuroscience, 81(1), 213\u2013222.","DOI":"10.1016\/S0306-4522(97)00186-3"},{"key":"663_CR2","doi-asserted-by":"crossref","unstructured":"Aeschbacj, D., Borbely, A.A. (1993). All-night dynamics of the human sleep EEG. Journal of Sleep Research, 2(2), 70\u201381.","DOI":"10.1111\/j.1365-2869.1993.tb00065.x"},{"issue":"27","key":"663_CR3","doi-asserted-by":"publisher","first-page":"11262","DOI":"10.1523\/JNEUROSCI.5867-12.2013","volume":"33","author":"MM Ali","year":"2013","unstructured":"Ali, M. M., Sellers, K. K., & Fr\u00f6hlich, F. (2013). Transcranial alternating current stimulation modulates large-scale cortical network activity by network resonance. The Journal of Neuroscience, 33(27), 11262\u201311275. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.5867-12.2013\n                    \n                   PubMed.","journal-title":"The Journal of Neuroscience"},{"key":"663_CR4","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1113\/jphysiol.1973.sp010410","volume":"235","author":"CR Anderson","year":"1973","unstructured":"Anderson, C. R., & Stevens, C. F. (1973). Voltage clamp analysis of acetylcholine produced ebd-plate current fluctuations at frog neuromoscular junction. Journal of Physiology, 235, 655\u2013691 PubMed.","journal-title":"Journal of Physiology"},{"issue":"19","key":"663_CR5","doi-asserted-by":"crossref","first-page":"8691","DOI":"10.1523\/JNEUROSCI.22-19-08691.2002","volume":"22","author":"M Bazhenov","year":"2002","unstructured":"Bazhenov, M., Timofeev, I., Steriade, M., & Sejnowski, T. J. (2002). Model of thalamocortical slow-wave sleep oscillations and transitions to activated States. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(19), 8691\u20138704 PubMed.","journal-title":"The Journal of neuroscience : the official journal of the Society for Neuroscience"},{"issue":"3","key":"663_CR6","doi-asserted-by":"publisher","first-page":"1562","DOI":"10.1152\/jn.90613.2008","volume":"100","author":"M Bazhenov","year":"2008","unstructured":"Bazhenov, M., Rulkov, N. F., & Timofeev, I. (2008). Effect of synaptic connectivity on long-range synchronization of fast cortical oscillations. Journal of neurophysiology, 100(3), 1562\u20131575. \n                    https:\/\/doi.org\/10.1152\/jn.90613.2008\n                    \n                   PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"5","key":"663_CR7","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/0013-4694(81)90225-X","volume":"51","author":"AA Borbely","year":"1981","unstructured":"Borbely, A. A., Baumann, F., Brandeis, D., Strauch, I., & Lehmann, D. (1981). Sleep deprivation: effect on sleep stages and EEG power density in man. Electroencephalography and Clinical Neurophysiology, 51(5), 483\u2013495 Epub 1981\/05\/01. PubMed.","journal-title":"Electroencephalography and Clinical Neurophysiology"},{"issue":"5","key":"663_CR8","doi-asserted-by":"publisher","first-page":"3637","DOI":"10.1152\/jn.00686.2005","volume":"94","author":"R Brette","year":"2005","unstructured":"Brette, R., & Gerstner, W. (2005). Adaptive exponential integrate-and-fire model as an effective description of neuronal activity. Journal of neurophysiology, 94(5), 3637\u20133642. \n                    https:\/\/doi.org\/10.1152\/jn.00686.2005\n                    \n                   PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"Pt 3","key":"663_CR9","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1113\/jphysiol.1997.sp022053","volume":"500","author":"EH Buhl","year":"1997","unstructured":"Buhl, E. H., Tams, G., Szilgyi, T., Stricker, C., Paulsen, O., & Somogyi, P. (1997). Effect, number and location of synapses made by single pyramidal cells onto aspiny interneurones of cat visual cortex. The Journal of physiology, 500(Pt 3), 689\u2013713 PubMed.","journal-title":"The Journal of physiology"},{"issue":"5","key":"663_CR10","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1162\/089976602753633349","volume":"14","author":"ARR Casti","year":"2002","unstructured":"Casti, A.R.R., Omurtag, A., Sornborger, A., Kaplan, E., Knight, B., Victor, J., et al. (2002). A population study of integrate-and-fire-or-burst neurons. Neural computation, 14(5), 957\u2013986. \n                    https:\/\/doi.org\/10.1162\/089976602753633349\n                    \n                   PubMed.","journal-title":"Neural computation"},{"key":"663_CR11","doi-asserted-by":"crossref","unstructured":"Chauvette, S., Volgushev, M., & Timofeev, I. (2010). Origin of Active States in Local Neocortical Networks during Slow Sleep Oscillation. Cerebral Cortex, p., 2660\u20132674.","DOI":"10.1093\/cercor\/bhq009"},{"issue":"42","key":"663_CR12","doi-asserted-by":"publisher","first-page":"14998","DOI":"10.1523\/JNEUROSCI.2339-11.2011","volume":"31","author":"S Chauvette","year":"2011","unstructured":"Chauvette, S., Crochet, S., Volgushev, M., & Timofeev, I. (2011). Properties of Slow Oscillation during Slow-Wave Sleep and Anesthesia in Cats. The Journal of Neuroscience., 31(42), 14998\u201315008. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.2339-11.2011\n                    \n                  .","journal-title":"The Journal of Neuroscience."},{"issue":"Pt 16","key":"663_CR13","doi-asserted-by":"publisher","first-page":"3987","DOI":"10.1113\/jphysiol.2012.227462","volume":"590","author":"J-Y Chen","year":"2012","unstructured":"Chen, J.-Y., Chauvette, S., Skorheim, S., Timofeev, I., & Bazhenov, M. (2012). Interneuron-mediated inhibition synchronizes neuronal activity during slow oscillation. The Journal of physiology, 590(Pt 16), 3987\u20134010. \n                    https:\/\/doi.org\/10.1113\/jphysiol.2012.227462\n                    \n                   PubMed.","journal-title":"The Journal of physiology"},{"issue":"5","key":"663_CR14","doi-asserted-by":"publisher","first-page":"2707","DOI":"10.1152\/jn.00845.2002","volume":"89","author":"A Compte","year":"2003","unstructured":"Compte, A., Sanchez-Vives, M. V., McCormick, D. A., & Wang, X.-J. (2003). Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network model. Journal of Neurophysiology, 89(5), 2707\u20132725.","journal-title":"Journal of Neurophysiology"},{"issue":"1","key":"663_CR15","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1523\/JNEUROSCI.15-01-00604.1995","volume":"15","author":"D Contreras","year":"1995","unstructured":"Contreras, D., & Steriade, M. (1995). Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships. The Journal of neuroscience, 15(1), 604\u2013622 PubMed.","journal-title":"The Journal of neuroscience"},{"key":"663_CR16","doi-asserted-by":"crossref","unstructured":"Contreras, D., Timofeev, I., & Steriade, M. (1996). Mechanisms of long-lasting hyperpolarizations underlying slow sleep oscillations in cat corticothalamic networks. Journal of Physiology, 251\u2013264.","DOI":"10.1113\/jphysiol.1996.sp021488"},{"key":"663_CR17","doi-asserted-by":"crossref","unstructured":"Contreras, D., Destexhe, A., Sejnowski, T., & Steriade, M. (1997). Spatiotemporal patterns of spindle oscillations in cortex and thalamus. Journal of Neuroscience, 1179\u20131196.","DOI":"10.1523\/JNEUROSCI.17-03-01179.1997"},{"issue":"2","key":"663_CR18","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1023\/A:1008843412952","volume":"4","author":"SM Crook","year":"1997","unstructured":"Crook, S. M., Ermentrout, G. B., Vanier, M. C., & Bower, J. M. (1997). The role of axonal delay in the synchronization of networks of coupled cortical oscillators. Journal of Computational Neuroscience, 4(2), 161\u2013172. \n                    https:\/\/doi.org\/10.1023\/A:1008843412952\n                    \n                   PubMed.","journal-title":"Journal of Computational Neuroscience"},{"issue":"3","key":"663_CR19","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1007\/s10827-009-0164-4","volume":"27","author":"A Destexhe","year":"2009","unstructured":"Destexhe, A. (2009). Self-sustained asynchronous irregular states and Up\u2013Down states in thalamic, cortical and thalamocortical networks of nonlinear integrate-and-fire neurons. Journal of Computational Neuroscience, 27(3), 493\u2013506. \n                    https:\/\/doi.org\/10.1007\/s10827-009-0164-4\n                    \n                   PubMed.","journal-title":"Journal of Computational Neuroscience"},{"key":"663_CR20","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1152\/jn.1999.81.4.1531","volume":"81","author":"A Destexhe","year":"1999","unstructured":"Destexhe, A., & Pare, D. (1999). Impact of Network Activity on the Integrative Properties of Neocortical Pyramidal Neurons In Vivo. Journal of Neurophysiology, 81, 1531\u20131547 PubMed.","journal-title":"Journal of Neurophysiology"},{"issue":"2","key":"663_CR21","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1152\/jn.1994.72.2.803","volume":"72","author":"A Destexhe","year":"1994","unstructured":"Destexhe, A., Contreras, D., Sejnowski, T. J., & Steriade, M. (1994). A Model of Spindle Rhythmicity in the Isolated Thalamic Reticular Nucleus. Journal of neurophysiology, 72(2), 803\u2013818 PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"2","key":"663_CR22","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1038\/nrn2762","volume":"11","author":"S Diekelmann","year":"2010","unstructured":"Diekelmann, S., & Born, J. (2010). The memory function of sleep. Nature reviews Neuroscience, 11(2), 114\u2013126. \n                    https:\/\/doi.org\/10.1038\/nrn2762\n                    \n                   PubMed.","journal-title":"Nature reviews Neuroscience"},{"issue":"12","key":"663_CR23","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.1093\/sleep\/30.12.1617","volume":"30","author":"SK Esser","year":"2007","unstructured":"Esser, S. K., Hill, S. L., & Tononi, G. (2007). Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves. Sleep, 30(12), 1617\u20131630 PubMed PMID: 18246972; PubMed Central PMCID: PMCPMC2276134.","journal-title":"Sleep"},{"issue":"1","key":"663_CR24","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1113\/jphysiol.1996.sp021366","volume":"493","author":"IA Fleidervish","year":"1996","unstructured":"Fleidervish, I. A., Friedman, A., & Gutnick, M. J. (1996). Slow inactivation of Na current and slow cumulative spike adaptation in mouse and guinea-pig neocortical neurones in slices. Journal of Physiology, 493(1), 83\u201397 PubMed.","journal-title":"Journal of Physiology"},{"key":"663_CR25","doi-asserted-by":"crossref","unstructured":"Gil, Z., Connors, B. W., & Amitai, Y. (1997). Differential regulation of neocortical synapses by neuromodulators and activity. Neuron, 679-86.","DOI":"10.1016\/S0896-6273(00)80380-3"},{"issue":"Pt 2","key":"663_CR26","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1113\/jphysiol.2005.097006","volume":"571","author":"D Guan","year":"2006","unstructured":"Guan, D., Lee, J. C. F., Tkatch, T., Surmeier, D. J., Armstrong, W. E., & Foehring, R. C. (2006). Expression and biophysical properties of Kv1 channels in supragranular neocortical pyramidal neurones. The Journal of physiology, 571(Pt 2), 371\u2013389. \n                    https:\/\/doi.org\/10.1113\/jphysiol.2005.097006\n                    \n                   PubMed.","journal-title":"The Journal of physiology"},{"issue":"3","key":"663_CR27","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1152\/jn.00933.2006","volume":"97","author":"D Guan","year":"2007","unstructured":"Guan, D., Lee, J. C. F., Higgs, M. H., Spain, W. J., & Foehring, R. C. (2007). Functional roles of Kv1 channels in neocortical pyramidal neurons. Journal of neurophysiology, 97(3), 1931\u20131940. \n                    https:\/\/doi.org\/10.1152\/jn.00933.2006\n                    \n                   PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"Cv)","key":"663_CR28","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1162\/089976698300017331","volume":"10","author":"BS Gutkin","year":"1998","unstructured":"Gutkin, B. S., & Ermentrout, G. B. (1998). Dynamics of membrane excitability determine interspike interval variability: a link between spike generation mechanisms and cortical spike train statistics. Neural computation, 10(Cv)), 1047\u20131065. \n                    https:\/\/doi.org\/10.1162\/089976698300017331\n                    \n                   PubMed.","journal-title":"Neural computation"},{"issue":"3","key":"663_CR29","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1152\/jn.00915.2004","volume":"93","author":"S Hill","year":"2005","unstructured":"Hill, S., & Tononi, G. (2005). Modeling sleep and wakefulness in the thalamocortical system. Journal of Neurophysiology, 93(3), 1671\u20131698 PubMed.","journal-title":"Journal of Neurophysiology"},{"key":"663_CR30","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1113\/jphysiol.1952.sp004764","volume":"117","author":"A Hodgkin","year":"1952","unstructured":"Hodgkin, A., & Huxley, A. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. Journal Physiol, 117, 500\u2013544. \n                    https:\/\/doi.org\/10.1016\/S0092-8240(05)80004-7\n                    \n                   PubMed.","journal-title":"Journal Physiol"},{"issue":"2","key":"663_CR31","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s004220050279","volume":"127","author":"FC Hoppensteadt","year":"1996","unstructured":"Hoppensteadt, F. C., & Izhikevich, E. M. (1996). Biological Cybernetics. Biological cybernetics, 127(2), 117\u2013127 PubMed.","journal-title":"Biological cybernetics"},{"issue":"5","key":"663_CR32","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1109\/TNN.2004.832719","volume":"15","author":"EM Izhikevich","year":"2004","unstructured":"Izhikevich, E. M. (2004). Which model to use for cortical spiking neurons? IEEE Transactions on Neural Networks, 15(5), 1063\u20131070. \n                    https:\/\/doi.org\/10.1109\/TNN.2004.832719\n                    \n                   PubMed.","journal-title":"IEEE Transactions on Neural Networks"},{"issue":"9","key":"663_CR33","doi-asserted-by":"publisher","first-page":"3593","DOI":"10.1073\/pnas.0712231105","volume":"105","author":"EM Izhikevich","year":"2008","unstructured":"Izhikevich, E. M., & Edelman, G. M. (2008). Large-scale model of mammalian thalamocortical systems. Proceedings of the National Academy of Sciences of the United States of America, 105(9), 3593\u20133598. \n                    https:\/\/doi.org\/10.1073\/pnas.0712231105\n                    \n                   PubMed.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"663_CR34","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1085\/jgp.59.6.734","volume":"59","author":"BW Knight","year":"1972","unstructured":"Knight, B. W. (1972). Dynamics of encoding in a population of neurons. The Journal of general physiology, 59(6), 734\u2013766. \n                    https:\/\/doi.org\/10.1085\/jgp.59.6.734\n                    \n                   PubMed.","journal-title":"The Journal of general physiology"},{"key":"663_CR35","unstructured":"Kuznetsov, Y., (1998) Elements of Applied Bifurcation Theory: Springer-Verlag New York. 591 p."},{"key":"663_CR36","doi-asserted-by":"crossref","unstructured":"Lee, M. G., Manns, I. D., Alonso, A., & Jones, B. E. (2004). Sleep-Wake Related Discharge Properties of Basal Forebrain Neurons Recorded With Micropipettes in Head-Fixed Rats. Journal of Neurophysiology, 1182\u20131198.","DOI":"10.1152\/jn.01003.2003"},{"issue":"16","key":"663_CR37","doi-asserted-by":"publisher","first-page":"5689","DOI":"10.1523\/JNEUROSCI.1156-13.2014","volume":"34","author":"M Lemieux","year":"2014","unstructured":"Lemieux, M., Chen, J.-Y., Lonjers, P., Bazhenov, M., & Timofeev, I. (2014). The Impact of Cortical Deafferentation on the Neocortical Slow Oscillation. The Journal of Neuroscience., 34(16), 5689\u20135703. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.1156-13.2014\n                    \n                  .","journal-title":"The Journal of Neuroscience."},{"issue":"6","key":"663_CR38","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/0896-6273(95)90020-9","volume":"15","author":"ZF Mainen","year":"1995","unstructured":"Mainen, Z. F., Joerges, J., Huguenard, J. R., & Sejnowski, T. J. (1995). A model of spike initiation in neocortical pyramidal neurons. Neuron, 15(6), 1427\u20131439. \n                    https:\/\/doi.org\/10.1016\/0896\u20136273(95)90020-9\n                    \n                   PubMed.","journal-title":"Neuron"},{"issue":"31","key":"663_CR39","doi-asserted-by":"publisher","first-page":"6862","DOI":"10.1523\/JNEUROSCI.1318-04.2004","volume":"24","author":"M Massimini","year":"2004","unstructured":"Massimini, M., Huber, R., Ferrarelli, F., Hill, S., & Tononi, G. (2004). The Sleep Slow Oscillation as a Traveling Wave. The Journal of Neuroscience., 24(31), 6862\u20136870. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.1318-04.2004\n                    \n                  .","journal-title":"The Journal of Neuroscience."},{"issue":"20","key":"663_CR40","doi-asserted-by":"publisher","first-page":"8496","DOI":"10.1073\/pnas.0702495104","volume":"104","author":"M Massimini","year":"2007","unstructured":"Massimini, M., Ferrarelli, F., Esser, S. K., Riedner, B. A., Huber, R., Murphy, M., et al. (2007). Triggering sleep slow waves by transcranial magnetic stimulation. Proceedings of the National Academy of Sciences., 104(20), 8496\u20138501. \n                    https:\/\/doi.org\/10.1073\/pnas.0702495104\n                    \n                  .","journal-title":"Proceedings of the National Academy of Sciences."},{"key":"663_CR41","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0301-0082(92)90012-4","volume":"39","author":"DA McCormick","year":"1992","unstructured":"McCormick, D. A. (1992). Neurotransmitter Actions in the Thalamus and Cerebral Cortex and Their Role in Neuromodulation of Thalamocortical Activity. Pogress in Nuerobiology, 39, 337\u2013388 PubMed.","journal-title":"Pogress in Nuerobiology"},{"key":"663_CR42","doi-asserted-by":"crossref","unstructured":"McCormick, D. A., Pape, H. C., & Williamson, A. (1991). Actions of norepinephrine in the cerebral cortex and thalamus: implications for function of the central noradrenergic system. Progress in Brain Research, 293\u2013305.","DOI":"10.1016\/S0079-6123(08)63817-0"},{"key":"663_CR43","doi-asserted-by":"crossref","unstructured":"Molle, M., Marshall, L., Gais, S., & Born, J. (2002). Grouping of spindle activity during slow oscillations in human non-rapid eye movement sleep. Journal of Neuroscience, 10941\u201310947.","DOI":"10.1523\/JNEUROSCI.22-24-10941.2002"},{"issue":"1","key":"663_CR44","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1152\/physrev.1990.70.1.165","volume":"70","author":"S Redman","year":"1990","unstructured":"Redman, S. (1990). Quantal Analysis of Synaptic Potentials in Neurons of the Central Nervous System. Physiological reviews, 70(1), 165\u2013198 PubMed.","journal-title":"Physiological reviews"},{"issue":"4","key":"663_CR45","doi-asserted-by":"publisher","first-page":"041922","DOI":"10.1103\/PhysRevE.65.041922","volume":"65","author":"NF Rulkov","year":"2002","unstructured":"Rulkov, N. F. (2002). Modeling of spiking-bursting neural behavior using two-dimensional map. Physical Review E, 65(4), 041922. \n                    https:\/\/doi.org\/10.1103\/PhysRevE.65.041922\n                    \n                   PubMed.","journal-title":"Physical Review E"},{"issue":"3\u20134","key":"663_CR46","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s10867-008-9079-y","volume":"34","author":"NF Rulkov","year":"2008","unstructured":"Rulkov, N. F., & Bazhenov, M. (2008). Oscillations and Synchrony in Large-scale Cortical Network Models. Journal of Biological Physics, 34(3\u20134), 279\u2013299. \n                    https:\/\/doi.org\/10.1007\/s10867-008-9079-y\n                    \n                   PubMed.","journal-title":"Journal of Biological Physics"},{"issue":"2","key":"663_CR47","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1023\/B:JCNS.0000037683.55688.7e","volume":"17","author":"NF Rulkov","year":"2004","unstructured":"Rulkov, N. F., Timofeev, I., & Bazhenov, M. (2004). Oscillations in large-scale cortical networks: map-based model. Journal of Computational Neuroscience, 17(2), 203\u2013223. \n                    https:\/\/doi.org\/10.1023\/B:JCNS.0000037683.55688.7e\n                    \n                   PubMed.","journal-title":"Journal of Computational Neuroscience"},{"key":"663_CR48","doi-asserted-by":"publisher","unstructured":"Rulkov, N. F., Hunt, A. M., Rulkov, P. N., & Maximov, A. G. (2016). Quantization of Map-Based neuronal model for embedded simulations of neurobiological networks in real-time. American Journal of Engineering and Applied Sciences, 9(4), 973\u2013984.. \n                    https:\/\/doi.org\/10.3844\/ajeassp 2016.973.984\n                    \n                  .","DOI":"10.3844\/ajeassp%202016.973.984"},{"key":"663_CR49","doi-asserted-by":"crossref","unstructured":"Runfeldt, M. J., Sadovsky, A. J., & MacLean, J. N. (2014). Acetylcholine functionally reorganizes neocortical microcircuits. Journal of Neurophysiology, 112(5), 1205\u201316.","DOI":"10.1152\/jn.00071.2014"},{"issue":"4","key":"663_CR50","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.1152\/jn.1996.75.4.1573","volume":"75","author":"PA Salin","year":"1996","unstructured":"Salin, P. A., & Prince, D. A. (1996). Spontaneous GABAA Receptor-Mediated Inhibitory Currents in Adult Rat Somatosensory Cortex. Journal of neurophysiology, 75(4), 1573\u20131588 PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"10","key":"663_CR51","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1038\/79848","volume":"3","author":"MV Sanchez-Vives","year":"2000","unstructured":"Sanchez-Vives, M. V., & McCormick, D. A. (2000). Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nature neuroscience, 3(10), 1027\u20131034. \n                    https:\/\/doi.org\/10.1038\/79848\n                    \n                   PubMed PMID: Sanchez-Vives2000.","journal-title":"Nature neuroscience"},{"issue":"26","key":"663_CR52","doi-asserted-by":"publisher","first-page":"8875","DOI":"10.1523\/JNEUROSCI.4460-13.2014","volume":"34","author":"M Sheroziya","year":"2014","unstructured":"Sheroziya, M., & Timofeev, I. (2014). Global Intracellular Slow-Wave Dynamics of the Thalamocortical System. Journal of Neuroscience, 34(26), 8875\u20138893. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.4460-13.2014\n                    \n                   PubMed.","journal-title":"Journal of Neuroscience"},{"key":"663_CR53","doi-asserted-by":"crossref","unstructured":"Shilnikov, A. L., & Rulkov, N. F. (2003). Origin of chaos in a two-dimensional map modeling spiking-bursting neural activity. Internation Journal of Bifurcation and Chaos, 13(11), 3325\u20133340 PubMed.","DOI":"10.1142\/S0218127403008521"},{"issue":"2\u20133","key":"663_CR54","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.physleta.2004.05.062","volume":"328","author":"AL Shilnikov","year":"2004","unstructured":"Shilnikov, A. L., & Rulkov, N. F. (2004). Subthreshold oscillations in a map-based neuron model. Physics Letters A, 328(2\u20133), 177\u2013184. \n                    https:\/\/doi.org\/10.1016\/j.physleta.2004.05.062\n                    \n                   PubMed.","journal-title":"Physics Letters A"},{"issue":"32","key":"663_CR55","doi-asserted-by":"crossref","first-page":"10388","DOI":"10.1523\/JNEUROSCI.23-32-10388.2003","volume":"23","author":"Y Shu","year":"2003","unstructured":"Shu, Y., Hasenstaub, A., Badoual, M., Bal, T., & McCormick, D. A. (2003). Barrages of Synaptic Activity Control the Gain and Sensitivity of Cortical Neurons. The Journal of Neuroscience., 23(32), 10388\u201310401.","journal-title":"The Journal of Neuroscience."},{"key":"663_CR56","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/j.1749-6632.1998.tb09054.x","volume":"860","author":"KA Sigvardt","year":"1998","unstructured":"Sigvardt, K. A., & Miller, W. L. (1998). Analysis and modeling of the locomotor central pattern generator as a network of coupled oscillators. Annals of the New York Academy of Sciences, 860, 250\u2013265. \n                    https:\/\/doi.org\/10.1111\/j.1749-6632.1998.tb09054.x\n                    \n                   PubMed.","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"23","key":"663_CR57","doi-asserted-by":"crossref","first-page":"10242","DOI":"10.1523\/JNEUROSCI.22-23-10242.2002","volume":"22","author":"GD Smith","year":"2002","unstructured":"Smith, G. D., & Sherman, S. M. (2002). Detectability of excitatory versus inhibitory drive in an integrate-and-fire-or-burst thalamocortical relay neuron model. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(23), 10242\u201310250 PubMed.","journal-title":"The Journal of neuroscience : the official journal of the Society for Neuroscience"},{"issue":"1","key":"663_CR58","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1152\/jn.2000.83.1.588","volume":"83","author":"GD Smith","year":"2000","unstructured":"Smith, G. D., Cox, C. L., Sherman, S. M., & Rinzel, J. (2000). Fourier analysis of sinusoidally driven thalamocortical relay neurons and a minimal integrate-and-fire-or-burst model. Journal of neurophysiology, 83(1), 588\u2013610 PubMed.","journal-title":"Journal of neurophysiology"},{"key":"663_CR59","doi-asserted-by":"crossref","unstructured":"Softky, W. R., & Koch, C. (1993). The highly irregular firing of cortical cells is inconsistent with temporal integration of random EPSPs. The Journal of Neuroscience, 13(1), 334\u2013350 PubMed.","DOI":"10.1523\/JNEUROSCI.13-01-00334.1993"},{"key":"663_CR60","doi-asserted-by":"crossref","first-page":"3252","DOI":"10.1523\/JNEUROSCI.13-08-03252.1993","volume":"13","author":"M Steriade","year":"1993","unstructured":"Steriade, M., Nu\u00f1ez, A., & Amzica, F. (1993a). A novel slow (<1 Hz) oscillation of neocortical neurons in vivo : depolarizing and hyperpolarizing components. The Journal of Neuroscience, 13, 3252\u20133265.","journal-title":"The Journal of Neuroscience"},{"issue":"8","key":"663_CR61","doi-asserted-by":"crossref","first-page":"3266","DOI":"10.1523\/JNEUROSCI.13-08-03266.1993","volume":"13","author":"M Steriade","year":"1993","unstructured":"Steriade, M., Nuez, A., & Amzica, F. (1993b). Intracellular analysis of relations between the slow (< 1 Hz) neocortical oscillation and other sleep rhythms of the electroencephalogram. The Journal of neuroscience, 13(8), 3266\u20133283 PubMed.","journal-title":"The Journal of neuroscience"},{"key":"663_CR62","doi-asserted-by":"crossref","unstructured":"Steriade, M., Contreras, D., Curro Dossi, R., & Nunez, A. (1993c). The Slow (<1 Hz) Oscillation in Reticular Thalamic and Thalamocortical Neurons: Scenario of Sleep Rhythm Generation in Interacting Thalamic and Neocortical Networks. The Journal of Neuroscience. p., 3284\u20133299.","DOI":"10.1523\/JNEUROSCI.13-08-03284.1993"},{"issue":"5134","key":"663_CR63","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1126\/science.8235588","volume":"262","author":"M Steriade","year":"1993","unstructured":"Steriade, M., McCormick, D. A., & Sejnowski, T. J. (1993d). Thalamocortical oscillations in the sleeping and aroused brain. Science, 262(5134), 679\u2013685.","journal-title":"Science"},{"issue":"5","key":"663_CR64","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1152\/jn.2001.85.5.1969","volume":"85","author":"M Steriade","year":"2001","unstructured":"Steriade, M., Timofeev, I., & Grenier, F. (2001). Natural waking and sleep states: a view from inside neocortical neurons. Journal of neurophysiology, 85(5), 1969\u20131985. \n                    https:\/\/doi.org\/10.1016\/j.neuroimage.2009.03.074\n                    \n                   PubMed.","journal-title":"Journal of neurophysiology"},{"issue":"5","key":"663_CR65","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1152\/jn.1998.80.5.2268","volume":"80","author":"M Tanabe","year":"1998","unstructured":"Tanabe, M., Ghwiler, B. H., & Gerber, U. (1998). L-Type Ca2+ channels mediate the slow Ca2+\u2212dependent afterhyperpolarization current in rat CA3 pyramidal cells in vitro. Journal of neurophysiology, 80(5), 2268\u20132273 PubMed.","journal-title":"Journal of neurophysiology"},{"key":"663_CR66","unstructured":"Timofeev, I., Bazhenov, M. (2005). Mechanisms and biological role of thalamocortical oscillations. Frank Columbus ed. Trends in Chronobiology Research: Nova Sceince Publishers, Inc.;p. 1-47."},{"issue":"6","key":"663_CR67","doi-asserted-by":"publisher","first-page":"4152","DOI":"10.1152\/jn.1996.76.6.4152","volume":"76","author":"I Timofeev","year":"1996","unstructured":"Timofeev, I., & Steriade, M. (1996). Low-frequency rhythms in the thalamus of intact-cortex and decorticated cats. Journal of Neurophysiology, 76(6), 4152\u20134168 PubMed.","journal-title":"Journal of Neurophysiology"},{"key":"663_CR68","doi-asserted-by":"crossref","unstructured":"Timofeev, I., Contreras, D., & Steriade, M. (1996). Synaptic responsiveness of cortical and thalamic neurones during various phases of slow sleep oscillation in cat. Journal of Physiology, 494(Pt 1), 265\u2013278.","DOI":"10.1113\/jphysiol.1996.sp021489"},{"issue":"12","key":"663_CR69","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1093\/cercor\/10.12.1185","volume":"10","author":"I Timofeev","year":"2000","unstructured":"Timofeev, I., Grenier, F., Bazhenov, M., Sejnowski, T. J., & Steriade, M. (2000a). Origin of slow cortical oscillations in deafferented cortical slabs. Cerebral cortex, 10(12), 1185\u20131199. \n                    https:\/\/doi.org\/10.1093\/cercor\/10.12.1185\n                    \n                   PubMed.","journal-title":"Cerebral cortex"},{"key":"663_CR70","doi-asserted-by":"crossref","unstructured":"Timofeev, I., Grenier, F., & Steriade, M. (2000b). Impact of intrinsic properties and synaptic factors on the activity of neocortical networks in vivo. J Physiol (Paris), 343\u2013355.","DOI":"10.1016\/S0928-4257(00)01097-4"},{"issue":"4","key":"663_CR71","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1073\/pnas.98.4.1924","volume":"98","author":"I Timofeev","year":"2001","unstructured":"Timofeev, I., Grenier, F., & Steriade, M. (2001). Disfacilitation and active inhibition in the neocortex during the natural sleep-wake cycle: An intracellular study. Proceedings of the National Academy of Sciences., 98(4), 1924\u20131929. \n                    https:\/\/doi.org\/10.1073\/pnas.98.4.1924\n                    \n                  .","journal-title":"Proceedings of the National Academy of Sciences."},{"issue":"2","key":"663_CR72","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1152\/jn.1991.66.2.635","volume":"66","author":"RD Traub","year":"1991","unstructured":"Traub, R. D., Wong, R. K., Miles, R., & Michelson, H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of Neurophysiology, 66(2), 635\u2013650 PubMed.","journal-title":"Journal of Neurophysiology"},{"key":"663_CR73","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511623202","volume-title":"Introduction to theoretical neurobiology","author":"HC Tuckwell","year":"1988","unstructured":"Tuckwell, H. C. (1988). Introduction to theoretical neurobiology (Vol. 2). Nonlinear and stochastic theries: Cambridge University Press."},{"issue":"21","key":"663_CR74","doi-asserted-by":"publisher","first-page":"5665","DOI":"10.1523\/JNEUROSCI.0279-06.2006","volume":"26","author":"M Volgushev","year":"2006","unstructured":"Volgushev, M., Chauvette, S., Mukovski, M., & Timofeev, I. (2006). Precise Long-Range Synchronization of Activity and Silence in Neocortical Neurons during Slow-Wave Sleep. The Journal of Neuroscience., 26(21), 5665\u20135672. \n                    https:\/\/doi.org\/10.1523\/JNEUROSCI.0279-06.2006\n                    \n                  .","journal-title":"The Journal of Neuroscience."},{"key":"663_CR75","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/B978-0-444-53839-0.00012-0","volume":"193","author":"M Volgushev","year":"2011","unstructured":"Volgushev, M., Chauvette, S., & Timofeev, I. (2011). Long-range correlation of the membrane potential in neocortical neurons during slow oscillation. Progress in brain research, 193, 181\u2013199. \n                    https:\/\/doi.org\/10.1016\/B978-0-444-53839-0.00012-0\n                    \n                   PubMed.","journal-title":"Progress in brain research"},{"issue":"15","key":"663_CR76","doi-asserted-by":"publisher","first-page":"4231","DOI":"10.1523\/JNEUROSCI.3648-15.2016","volume":"36","author":"Y Wei","year":"2016","unstructured":"Wei, Y., Krishnan, G. P., & Bazhenov, M. (2016). Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations. The Journal of Neuroscience., 36(15), 4231\u20134247. \n                    https:\/\/doi.org\/10.1523\/jneurosci.3648-15.2016\n                    \n                  .","journal-title":"The Journal of Neuroscience."},{"issue":"1","key":"663_CR77","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1023\/A:1008864410375","volume":"4","author":"TL Williams","year":"1997","unstructured":"Williams, T. L., & Bowtell, G. (1997). The calculation of frequency-shift functions for chains of coupled oscillators, with application to a network model of the lamprey locomotor pattern generator. Journal of Computational Neuroscience, 4(1), 47\u201355 PubMed.","journal-title":"Journal of Computational Neuroscience"}],"container-title":["Journal of Computational Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10827-017-0663-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10827-017-0663-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10827-017-0663-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T10:28:26Z","timestamp":1589711306000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10827-017-0663-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,12]]},"references-count":77,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["663"],"URL":"https:\/\/doi.org\/10.1007\/s10827-017-0663-7","relation":{},"ISSN":["0929-5313","1573-6873"],"issn-type":[{"value":"0929-5313","type":"print"},{"value":"1573-6873","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,12]]},"assertion":[{"value":"6 December 2016","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 September 2017","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2017","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2017","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}