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With the advent of digital technologies in education, innovative empathy training methods such as virtual reality, simulation training systems, mobile apps, and wearable devices, have emerged for teaching empathy. However, there is a gap in the literature regarding the efficacy of these technologies in teaching empathy, the most effective types, and the primary beneficiaries -students or advanced healthcare professionals-. This study aims to address this gap through a literature review following PRISMA guidelines. A comprehensive literature search was conducted in the PsychINFO, Scopus, PubMed, and Web of Science databases using specific keywords. Inclusion criteria for articles were established, and two researchers independently rated the selected articles, resolving any disagreements by consensus. Out of 1137 articles screened, a total of 14 articles were included in this review with a total of 1285 participants, who received empathic training integrated with the use of digital technologies. Only 9 articles defined the construct of empathy, focusing on cognitive, affective, clinical, or cultural aspects. Empathy was assessed with various methods and promoted through various digital technologies, including wearables (e.g. HMDs, SymPulse\u2122 armband) and non-wearable devices (computer monitors, Mobile Apps, Kinect System). Participants were primarily medical students (68.1%), with few healthcare workers (31.9%) and nurses (2.9%). All digital technologies effectively promoted empathy among the target population except for 3 studies that involved advanced career healthcare workers. This review highlights the potential efficacy of digital technologies in fostering empathy among medical students, though not as effectively among advanced healthcare professionals. These insights have implications for designing targeted educational programs that address the distinct needs of healthcare professionals at varying career stages. Limitations and future research directions are also discussed.<\/jats:p>","DOI":"10.1007\/s10916-025-02144-9","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T01:33:02Z","timestamp":1736818382000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Could Empathy Be Taught? 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