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Identifying Turing mechanisms in biological systems defines a challenging problem. This paper introduces an approach to the prediction of Turing parameter values from observed Turing patterns. The parameter values correspond to a parametrized system of reaction\u2013diffusion equations that generate Turing patterns as steady state. The Gierer\u2013Meinhardt model with four parameters is chosen as a case study. A novel invariant pattern representation based on resistance distance histograms is employed, along with Wasserstein kernels, in order to cope with the highly variable arrangement of local pattern structure that depends on the initial conditions which are assumed to be unknown. This enables us to compute physically plausible distances between patterns, to compute clusters of patterns and, above all, model parameter prediction based on training data that can be generated by numerical model evaluation with random initial data: for small training sets, classical state-of-the-art methods including operator-valued kernels outperform neural networks that are applied to raw pattern data, whereas for large training sets the latter are more accurate. A prominent property of our approach is that only a <jats:italic>single<\/jats:italic> pattern is required as input data for model parameter predicion. Excellent predictions are obtained for single parameter values and reasonably accurate results for jointly predicting all four parameter values.<\/jats:p>","DOI":"10.1007\/s10994-023-06334-9","type":"journal-article","created":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T19:02:02Z","timestamp":1686682922000},"page":"3151-3190","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Learning system parameters from turing patterns"],"prefix":"10.1007","volume":"112","author":[{"given":"David","family":"Schn\u00f6rr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8999-2338","authenticated-orcid":false,"given":"Christoph","family":"Schn\u00f6rr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,13]]},"reference":[{"key":"6334_CR1","unstructured":"Abadi, M., Agarwal, A., Barham, P., Brevdo, E., Chen, Z., Citro, C., Corrado, G. 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