{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:39:57Z","timestamp":1761561597905,"version":"3.38.0"},"reference-count":69,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2011,12,9]],"date-time":"2011-12-09T00:00:00Z","timestamp":1323388800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Cell Biochem"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1007\/s11010-011-1178-6","type":"journal-article","created":{"date-parts":[[2011,12,8]],"date-time":"2011-12-08T11:40:23Z","timestamp":1323344423000},"page":"257-268","source":"Crossref","is-referenced-by-count":69,"title":["Isolation and characterization of stem-like cells from a human ovarian cancer cell line"],"prefix":"10.1007","volume":"363","author":[{"given":"Lijuan","family":"Wang","sequence":"first","affiliation":[]},{"given":"Roman","family":"Mezencev","sequence":"additional","affiliation":[]},{"given":"Nathan J.","family":"Bowen","sequence":"additional","affiliation":[]},{"given":"Lilya V.","family":"Matyunina","sequence":"additional","affiliation":[]},{"given":"John F.","family":"McDonald","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2011,12,9]]},"reference":[{"key":"1178_CR1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3322\/caac.20073","volume":"60","author":"A Jemal","year":"2010","unstructured":"Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60:277\u2013300","journal-title":"CA Cancer J Clin"},{"key":"1178_CR2","doi-asserted-by":"crossref","first-page":"7439","DOI":"10.1158\/1078-0432.CCR-04-0683","volume":"10","author":"TJ Herzog","year":"2004","unstructured":"Herzog TJ (2004) Recurrent ovarian cancer: how important is it to treat to disease progression? Clin Cancer Res 10:7439\u20137449","journal-title":"Clin Cancer Res"},{"key":"1178_CR3","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.molonc.2010.06.005","volume":"4","author":"SP McDermott","year":"2010","unstructured":"McDermott SP, Wicha MS (2010) Targeting breast cancer stem cells. Mol Oncol 4:404\u2013419","journal-title":"Mol Oncol"},{"key":"1178_CR4","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/367645a0","volume":"367","author":"T Lapidot","year":"1994","unstructured":"Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367:645\u2013648","journal-title":"Nature"},{"key":"1178_CR5","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1073\/pnas.0530291100","volume":"100","author":"M Al-Hajj","year":"2003","unstructured":"Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983\u20133988","journal-title":"Proc Natl Acad Sci USA"},{"key":"1178_CR6","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nature03128","volume":"432","author":"SK Singh","year":"2004","unstructured":"Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB (2004) Identification of human brain tumour initiating cells. Nature 432:396\u2013401","journal-title":"Nature"},{"key":"1178_CR7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/nature05236","volume":"444","author":"S Bao","year":"2006","unstructured":"Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444:756\u2013760. doi: 10.1038\/nature05236","journal-title":"Nature"},{"key":"1178_CR8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/nature05372","volume":"445","author":"CA O\u2019Brien","year":"2007","unstructured":"O\u2019Brien CA, Pollett A, Gallinger S, Dick JE (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445:106\u2013110","journal-title":"Nature"},{"key":"1178_CR9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nature05384","volume":"445","author":"L Ricci-Vitiani","year":"2007","unstructured":"Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445:111\u2013115","journal-title":"Nature"},{"key":"1178_CR10","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.stem.2007.06.002","volume":"1","author":"PC Hermann","year":"2007","unstructured":"Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ, Heeschen C (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1:313\u2013323","journal-title":"Cell Stem Cell"},{"key":"1178_CR11","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1158\/0008-5472.CAN-06-2030","volume":"67","author":"C Li","year":"2007","unstructured":"Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, Wicha M, Clarke MF, Simeone DM (2007) Identification of pancreatic cancer stem cells. Cancer Res 67:1030\u20131037","journal-title":"Cancer Res"},{"key":"1178_CR12","doi-asserted-by":"crossref","first-page":"10946","DOI":"10.1158\/0008-5472.CAN-05-2018","volume":"65","author":"AT Collins","year":"2005","unstructured":"Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 65:10946\u201310951","journal-title":"Cancer Res"},{"key":"1178_CR13","first-page":"5379","volume":"43","author":"TC Hamilton","year":"1983","unstructured":"Hamilton TC, Young RC, McKoy WM, Grotzinger KR, Green JA, Chu EW, Whang-Peng J, Rogan AM, Green WR, Ozols RF (1983) Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors. Cancer Res 43:5379\u20135389","journal-title":"Cancer Res"},{"key":"1178_CR14","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1093\/jnci\/djj505","volume":"98","author":"M Diehn","year":"2006","unstructured":"Diehn M, Clarke MF (2006) Cancer stem cells and radiotherapy: new insights into tumor radioresistance. J Natl Cancer Inst 98:1755\u20131757","journal-title":"J Natl Cancer Inst"},{"key":"1178_CR15","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nrc1590","volume":"5","author":"M Dean","year":"2005","unstructured":"Dean M, Fojo T, Bates S (2005) Tumour stem cells and drug resistance. Nat Rev Cancer 5:275\u2013284","journal-title":"Nat Rev Cancer"},{"key":"1178_CR16","doi-asserted-by":"crossref","unstructured":"Wicha MS, Liu S and Dontu G (2006) Cancer stem cells: an old idea\u2013a paradigm shift. Cancer Res 66:1883\u20131890; discussion 1895\u20131896. doi: 10.1158\/0008-5472.CAN-05-3153","DOI":"10.1158\/0008-5472.CAN-05-3153"},{"key":"1178_CR17","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nrc1123","volume":"3","author":"R Agarwal","year":"2003","unstructured":"Agarwal R, Kaye SB (2003) Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3:502\u2013516","journal-title":"Nat Rev Cancer"},{"key":"1178_CR18","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1146\/annurev.cellbio.22.010305.104154","volume":"23","author":"NA Lobo","year":"2007","unstructured":"Lobo NA, Shimono Y, Qian D, Clarke MF (2007) The biology of cancer stem cells. Annu Rev Cell Dev Biol 23:675\u2013699","journal-title":"Annu Rev Cell Dev Biol"},{"key":"1178_CR19","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3109\/01913120903086072","volume":"33","author":"Q Gao","year":"2009","unstructured":"Gao Q, Geng L, Kvalheim G, Gaudernack G, Suo Z (2009) Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3. Ultrastruct Pathol 33:175\u2013181. doi: 10.1080\/01913120903086072","journal-title":"Ultrastruct Pathol"},{"key":"1178_CR20","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/abbs\/gmq067","volume":"42","author":"L Ma","year":"2010","unstructured":"Ma L, Lai D, Liu T, Cheng W, Guo L (2010) Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3. Acta Biochim Biophys Sin (Shanghai) 42:593\u2013602","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"1178_CR21","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0091-679X(08)00014-9","volume-title":"Stem Cell Culture","author":"P Cammareri","year":"2008","unstructured":"Cammareri P, Lombardo Y, Giovanna MF, Bonventre S, Todaro M, Stassi G (2008) Isolation and culture of colon cancer stem cells. In: Mather JP (ed) Stem Cell Culture, 1st edn. Academic Press, New York, pp 311\u2013324","edition":"1"},{"key":"1178_CR22","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1158\/0008-5472.CAN-04-3931","volume":"65","author":"SA Bapat","year":"2005","unstructured":"Bapat SA, Mali AM, Koppikar CB, Kurrey NK (2005) Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res 65:3025\u20133029","journal-title":"Cancer Res"},{"key":"1178_CR23","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1158\/0008-5472.CAN-08-0364","volume":"68","author":"S Zhang","year":"2008","unstructured":"Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, Yan PS, Huang TH, Nephew KP (2008) Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res 68:4311\u20134320","journal-title":"Cancer Res"},{"key":"1178_CR24","doi-asserted-by":"crossref","first-page":"158","DOI":"10.4161\/cc.8.1.7533","volume":"8","author":"AB Alvero","year":"2009","unstructured":"Alvero AB, Chen R, Fu HH, Montagna M, Schwartz PE, Rutherford T, Silasi DA, Steffensen KD, Waldstrom M, Visintin I, Mor G (2009) Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance. Cell Cycle 8:158\u2013166","journal-title":"Cell Cycle"},{"key":"1178_CR25","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/onc.2008.374","volume":"28","author":"T Baba","year":"2009","unstructured":"Baba T, Convery PA, Matsumura N, Whitaker RS, Kondoh E, Perry T, Huang Z, Bentley RC, Mori S, Fujii S, Marks JR, Berchuck A, Murphy SK (2009) Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene 28:209\u2013218","journal-title":"Oncogene"},{"key":"1178_CR26","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1038\/onc.2010.35","volume":"29","author":"MQ Gao","year":"2010","unstructured":"Gao MQ, Choi YP, Kang S, Youn JH, Cho NH (2010) CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells. Oncogene 29:2672\u20132680","journal-title":"Oncogene"},{"key":"1178_CR27","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1007\/s00018-010-0420-9","volume":"67","author":"MF Shi","year":"2010","unstructured":"Shi MF, Jiao J, Lu WG, Ye F, Ma D, Dong QG, Xie X (2010) Identification of cancer stem cell-like cells from human epithelial ovarian carcinoma cell line. Cell Mol Life Sci 67:3915\u20133925","journal-title":"Cell Mol Life Sci"},{"key":"1178_CR28","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.cell.2005.03.032","volume":"121","author":"CF Kim","year":"2005","unstructured":"Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S, Crowley D, Bronson RT, Jacks T (2005) Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121:823\u2013835","journal-title":"Cell"},{"key":"1178_CR29","doi-asserted-by":"crossref","first-page":"e3077","DOI":"10.1371\/journal.pone.0003077","volume":"3","author":"V Levina","year":"2008","unstructured":"Levina V, Marrangoni AM, De Marco R, Gorelik E, Lokshin AE (2008) Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS One 3:e3077","journal-title":"PLoS One"},{"key":"1178_CR30","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.stem.2007.08.014","volume":"1","author":"C Ginestier","year":"2007","unstructured":"Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS, Dontu G (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1:555\u2013567","journal-title":"Cell Stem Cell"},{"key":"1178_CR31","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1111\/j.1349-7006.2010.01700.x","volume":"101","author":"Z Du","year":"2010","unstructured":"Du Z, Li J, Wang L, Bian C, Wang Q, Liao L, Dou X, Bian X, Zhao RC (2010) Overexpression of DeltaNp63alpha induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway. Cancer Sci 101:2417\u20132424","journal-title":"Cancer Sci"},{"key":"1178_CR32","doi-asserted-by":"crossref","first-page":"13427","DOI":"10.1073\/pnas.0805706105","volume":"105","author":"L Vermeulen","year":"2008","unstructured":"Vermeulen L, Todaro M, de Sousa Mello F, Sprick MR, Kemper K, Perez Alea M, Richel DJ, Stassi G, Medema JP (2008) Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. Proc Natl Acad Sci USA 105:13427\u201313432","journal-title":"Proc Natl Acad Sci USA"},{"key":"1178_CR33","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.oraloncology.2010.11.011","volume":"47","author":"YC Lim","year":"2011","unstructured":"Lim YC, Oh SY, Cha YY, Kim SH, Jin X, Kim H (2011) Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas. Oral Oncol 47:83\u201391","journal-title":"Oral Oncol"},{"key":"1178_CR34","doi-asserted-by":"crossref","first-page":"9937","DOI":"10.1158\/0008-5472.CAN-10-0881","volume":"70","author":"JP Sullivan","year":"2010","unstructured":"Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD (2010) Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Res 70:9937\u20139948","journal-title":"Cancer Res"},{"key":"1178_CR35","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.2741\/3811","volume":"16","author":"MA Sanders","year":"2011","unstructured":"Sanders MA, Majumdar AP (2011) Colon cancer stem cells: implications in carcinogenesis. Front Biosci 16:1651\u20131662","journal-title":"Front Biosci"},{"key":"1178_CR36","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1158\/1535-7163.MCT-10-0563","volume":"9","author":"CN Landen Jr","year":"2010","unstructured":"Landen CN Jr, Goodman B, Katre AA, Steg AD, Nick AM, Stone RL, Miller LD, Mejia PV, Jennings NB, Gershenson DM, Bast RC Jr, Coleman RL, Lopez-Berestein G, Sood AK (2010) Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer. Mol Cancer Ther 9:3186\u20133199","journal-title":"Mol Cancer Ther"},{"key":"1178_CR37","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1158\/1055-9965.EPI-09-0865","volume":"19","author":"Y Su","year":"2010","unstructured":"Su Y, Qiu Q, Zhang X, Jiang Z, Leng Q, Liu Z, Stass SA, Jiang F (2010) Aldehyde dehydrogenase 1 A1-positive cell population is enriched in tumor-initiating cells and associated with progression of bladder cancer. Cancer Epidemiol Biomarkers Prev 19:327\u2013337","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"1178_CR38","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/labinvest.2009.127","volume":"90","author":"T Li","year":"2010","unstructured":"Li T, Su Y, Mei Y, Leng Q, Leng B, Liu Z, Stass SA, Jiang F (2010) ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients\u2019 outcome. Lab Invest 90:234\u2013244","journal-title":"Lab Invest"},{"key":"1178_CR39","doi-asserted-by":"crossref","first-page":"237","DOI":"10.2174\/157488808786734006","volume":"3","author":"JS Moreb","year":"2008","unstructured":"Moreb JS (2008) Aldehyde dehydrogenase as a marker for stem cells. Curr Stem Cell Res Ther 3:237\u2013246","journal-title":"Curr Stem Cell Res Ther"},{"key":"1178_CR40","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0301-472X(01)00757-3","volume":"30","author":"N Pineault","year":"2002","unstructured":"Pineault N, Helgason CD, Lawrence HJ, Humphries RK (2002) Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol 30:49\u201357","journal-title":"Exp Hematol"},{"key":"1178_CR41","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1126\/science.286.5439.531","volume":"286","author":"TR Golub","year":"1999","unstructured":"Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 286:531\u2013537","journal-title":"Science"},{"key":"1178_CR42","first-page":"325","volume-title":"Method in Cell Biology","author":"PE Roberts","year":"2008","unstructured":"Roberts PE (2008) Isolation and establishment of human tumor stem cells. In: Mather JP (ed) Method in Cell Biology, 1st edn. Academic Press, New York, pp 325\u2013342","edition":"1"},{"key":"1178_CR43","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0092-8674(74)90050-6","volume":"3","author":"VH Freedman","year":"1974","unstructured":"Freedman VH, Shin SI (1974) Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell 3:355\u2013359","journal-title":"Cell"},{"key":"1178_CR44","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.bcp.2010.04.010","volume":"80","author":"FA Kruyt","year":"2010","unstructured":"Kruyt FA, Schuringa JJ (2010) Apoptosis and cancer stem cells: implications for apoptosis targeted therapy. Biochem Pharmacol 80:423\u2013430. doi: 10.1016\/j.bcp.2010.04.010","journal-title":"Biochem Pharmacol"},{"key":"1178_CR45","doi-asserted-by":"crossref","first-page":"32848","DOI":"10.1074\/jbc.M313375200","volume":"279","author":"AJ Valentijn","year":"2004","unstructured":"Valentijn AJ, Gilmore AP (2004) Translocation of full-length bid to mitochondria during anoikis. J Biol Chem 279:32848\u201332857. doi: 10.1074\/jbc.M313375200","journal-title":"J Biol Chem"},{"key":"1178_CR46","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1757-2215-1-4","volume":"1","author":"MP Ponnusamy","year":"2008","unstructured":"Ponnusamy MP, Batra SK (2008) Ovarian cancer: emerging concept on cancer stem cells. J Ovarian Res 1:4","journal-title":"J Ovarian Res"},{"key":"1178_CR47","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/1476-4598-7-83","volume":"7","author":"J Veeck","year":"2008","unstructured":"Veeck J, Noetzel E, Bektas N, Jost E, Hartmann A, Knuchel R, Dahl E (2008) Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer. Mol Cancer 7:83","journal-title":"Mol Cancer"},{"key":"1178_CR48","first-page":"243","volume":"52","author":"D Cooper","year":"1985","unstructured":"Cooper D, Schermer A, Sun TT (1985) Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations. Lab Invest 52:243\u2013256","journal-title":"Lab Invest"},{"key":"1178_CR49","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.semcdb.2008.02.001","volume":"19","author":"B Baum","year":"2008","unstructured":"Baum B, Settleman J, Quinlan MP (2008) Transitions between epithelial and mesenchymal states in development and disease. Semin Cell Dev Biol 19:294\u2013308","journal-title":"Semin Cell Dev Biol"},{"key":"1178_CR50","doi-asserted-by":"crossref","first-page":"e12445","DOI":"10.1371\/journal.pone.0012445","volume":"5","author":"D Kong","year":"2010","unstructured":"Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, Sarkar FH (2010) Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One 5:e12445","journal-title":"PLoS One"},{"key":"1178_CR51","doi-asserted-by":"crossref","first-page":"e16466","DOI":"10.1371\/journal.pone.0016466","volume":"6","author":"C Chen","year":"2011","unstructured":"Chen C, Wei Y, Hummel M, Hoffmann TK, Gross M, Kaufmann AM, Albers AE (2011) Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS One 6:e16466","journal-title":"PLoS One"},{"key":"1178_CR52","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.cell.2008.03.027","volume":"133","author":"SA Mani","year":"2008","unstructured":"Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133:704\u2013715","journal-title":"Cell"},{"key":"1178_CR53","doi-asserted-by":"crossref","first-page":"15449","DOI":"10.1073\/pnas.1004900107","volume":"107","author":"JH Taube","year":"2010","unstructured":"Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani SA (2010) Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci USA 107:15449\u201315454. doi: 10.1073\/pnas.1004900107","journal-title":"Proc Natl Acad Sci USA"},{"key":"1178_CR54","first-page":"130","volume":"4","author":"JY Chai","year":"2010","unstructured":"Chai JY, Modak C, Mouazzen W, Narvaez R, Pham J (2010) Epithelial or mesenchymal: where to draw the line? Biosci Trends 4:130\u2013142","journal-title":"Biosci Trends"},{"key":"1178_CR55","volume-title":"Cancer modelling and simulation","author":"F Bussolino","year":"2003","unstructured":"Bussolino F, Arese M, Audero E, Giraudo E, Marchio S, Mitola S, Primo L, Serini G (2003) Biological aspects of tumour angiogenesis. In: Preziosi L (ed) Cancer modelling and simulation. CRC Press, USA"},{"key":"1178_CR56","doi-asserted-by":"crossref","first-page":"571783","DOI":"10.1155\/2010\/571783","volume":"2010","author":"CB Pollock","year":"2010","unstructured":"Pollock CB, Rodriguez O, Martin PL, Albanese C, Li X, Kopelovich L, Glazer RI (2010) Induction of metastatic gastric cancer by peroxisome proliferator-activated receptordelta activation. PPAR Res 2010:571783","journal-title":"PPAR Res"},{"key":"1178_CR57","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1038\/leu.2008.103","volume":"22","author":"B Chapuy","year":"2008","unstructured":"Chapuy B, Koch R, Radunski U, Corsham S, Cheong N, Inagaki N, Ban N, Wenzel D, Reinhardt D, Zapf A, Schweyer S, Kosari F, Klapper W, Truemper L, Wulf GG (2008) Intracellular ABC transporter A3 confers multidrug resistance in leukemia cells by lysosomal drug sequestration. Leukemia 22:1576\u20131586","journal-title":"Leukemia"},{"key":"1178_CR58","doi-asserted-by":"crossref","first-page":"14228","DOI":"10.1073\/pnas.0400067101","volume":"101","author":"C Hirschmann-Jax","year":"2004","unstructured":"Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK (2004) A distinct \u201cside population\u201d of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA 101:14228\u201314233","journal-title":"Proc Natl Acad Sci USA"},{"key":"1178_CR59","first-page":"6559","volume":"62","author":"K Katano","year":"2002","unstructured":"Katano K, Kondo A, Safaei R, Holzer A, Samimi G, Mishima M, Kuo YM, Rochdi M, Howell SB (2002) Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper. Cancer Res 62:6559\u20136565","journal-title":"Cancer Res"},{"key":"1178_CR60","first-page":"1217","volume":"11","author":"AG Eliopoulos","year":"1995","unstructured":"Eliopoulos AG, Kerr DJ, Herod J, Hodgkins L, Krajewski S, Reed JC, Young LS (1995) The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2. Oncogene 11:1217\u20131228","journal-title":"Oncogene"},{"key":"1178_CR61","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0065-230X(09)05005-2","volume":"105","author":"JY Djeu","year":"2009","unstructured":"Djeu JY, Wei S (2009) Clusterin and chemoresistance. Adv Cancer Res 105:77\u201392. doi: 10.1016\/S0065-230X(09)05005-2","journal-title":"Adv Cancer Res"},{"key":"1178_CR62","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/labinvest.2010.136","volume":"91","author":"R Bu","year":"2011","unstructured":"Bu R, Uddin S, Bavi P, Hussain AR, Al-Dayel F, Ghourab S, Ahmed M, Al-Kuraya KS (2011) HGF\/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. Lab Invest 91:124\u2013137. doi: 10.1038\/labinvest.2010.136","journal-title":"Lab Invest"},{"key":"1178_CR63","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1038\/onc.2009.478","volume":"29","author":"K Tajima","year":"2010","unstructured":"Tajima K, Ohashi R, Sekido Y, Hida T, Nara T, Hashimoto M, Iwakami S, Minakata K, Yae T, Takahashi F, Saya H, Takahashi K (2010) Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells. Oncogene 29:1941\u20131951","journal-title":"Oncogene"},{"key":"1178_CR64","doi-asserted-by":"crossref","first-page":"25617","DOI":"10.1074\/jbc.M202285200","volume":"277","author":"M Wu","year":"2002","unstructured":"Wu M, Xu LG, Li X, Zhai Z, Shu HB (2002) AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis. J Biol Chem 277:25617\u201325623. doi: 10.1074\/jbc.M202285200","journal-title":"J Biol Chem"},{"key":"1178_CR65","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ceb.2005.10.001","volume":"17","author":"SN Willis","year":"2005","unstructured":"Willis SN, Adams JM (2005) Life in the balance: how BH3-only proteins induce apoptosis. Curr Opin Cell Biol 17:617\u2013625. doi: 10.1016\/j.ceb.2005.10.001","journal-title":"Curr Opin Cell Biol"},{"key":"1178_CR66","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1634\/stemcells.2005-0282","volume":"24","author":"N Haraguchi","year":"2006","unstructured":"Haraguchi N, Utsunomiya T, Inoue H, Tanaka F, Mimori K, Barnard GF, Mori M (2006) Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells 24:506\u2013513","journal-title":"Stem Cells"},{"issue":"2","key":"1178_CR67","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.3390\/ijms12021009","volume":"12","author":"MP Ween","year":"2011","unstructured":"Ween MP, Oehler MK, Ricciardelli C (2011) Hyaluronan and CD44 in ovarian cancer metastasis. Int J Mol Sci 12(2):1009\u20131029","journal-title":"Int J Mol Sci"},{"key":"1178_CR68","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.arcmed.2005.11.014","volume":"37","author":"V Vital-Reyes","year":"2006","unstructured":"Vital-Reyes V, Rodriguez-Burford C, Chhieng DC, Oelschlager DK, Reyes-Fuentes A, Barnes M, Grizzle WE (2006) Celecoxib inhibits cellular growth, decreases Ki-67 expression and modifies apoptosis in ovarian cancer cell lines. Arch Med Res 37:689\u2013695","journal-title":"Arch Med Res"},{"key":"1178_CR69","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0026-895X(24)23027-3","volume":"55","author":"SF Liu","year":"1999","unstructured":"Liu SF, Ye X, Malik AB (1999) Pyrrolidine dithiocarbamate prevents I-kappaB degradation and reduces microvascular injury induced by lipopolysaccharide in multiple organs. Mol Pharmacol 55:658\u2013667","journal-title":"Mol Pharmacol"}],"container-title":["Molecular and Cellular Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-011-1178-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11010-011-1178-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11010-011-1178-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T05:15:13Z","timestamp":1742015713000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11010-011-1178-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,9]]},"references-count":69,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["1178"],"URL":"https:\/\/doi.org\/10.1007\/s11010-011-1178-6","relation":{},"ISSN":["0300-8177","1573-4919"],"issn-type":[{"type":"print","value":"0300-8177"},{"type":"electronic","value":"1573-4919"}],"subject":[],"published":{"date-parts":[[2011,12,9]]}}}