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Deep learning elevated notably in the field of image colorization in the past years. In this paper, we formulate image colorization methods relying on exemplar colorization and automatic colorization, respectively. For hybrid colorization, we select appropriate reference images to colorize the grayscale CT images. The colours of meat resemble those of human lungs, so the images of fresh pork, lamb, beef, and even rotten meat are collected as our dataset for model training. Three sets of training data consisting of meat images are analysed to extract the pixelar features for colorizing lung CT images by using an automatic approach. Pertaining to the results, we consider numerous methods (i.e., loss functions, visual analysis, PSNR, and SSIM) to evaluate the proposed deep learning models. Moreover, compared with other methods of colorizing lung CT images, the results of rendering the images by using deep learning methods are significantly genuine and promising. The metrics for measuring image similarity such as SSIM and PSNR have satisfactory performance, up to 0.55 and 28.0, respectively. Additionally, the methods may provide novel ideas for rendering grayscale X-ray images in airports, ferries, and railway stations.<\/jats:p>","DOI":"10.1007\/s11042-022-13062-0","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T13:14:46Z","timestamp":1650633286000},"page":"37805-37819","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Colorizing Grayscale CT images of human lungs using deep learning methods"],"prefix":"10.1007","volume":"81","author":[{"given":"Yuewei","family":"Wang","sequence":"first","affiliation":[]},{"given":"Wei Qi","family":"Yan","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"issue":"5","key":"13062_CR1","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/S0731-7085(99)00272-1","volume":"22","author":"S Agatonovic-Kustrin","year":"2000","unstructured":"Agatonovic-Kustrin S, Beresford R (2000) Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research. 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