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Although recent deep learning-based approaches are achieving high accuracy results in this task, research in this area is mainly focused on improving results using a single dataset for training and testing. This approach lacks generality when applied to new images or when using it in in-the-wild contexts due to diversity in humans (e.g., age, ethnicity) and differences in capture conditions (e.g., lighting or background). The cross-datasets approach can overcome these limitations. In this work we present a method to combine multiple datasets and we conduct an exhaustive evaluation of a proposed system based on a CNN analyzing and comparing performance using single and cross-dataset approaches with other architectures. Results using the proposed system ranged from 31.56% to 61.78% when used in a single-dataset approach with different well-known datasets and improved up to 73.05% when using a cross-dataset approach. Finally, to study the system and humans\u2019 performance in facial expressions classification, we compare the results of 253 participants with the system. 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