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The most commented on In-Stent Restenosis is excessive thrombus that squeezes the stent and leads to vessel occlusion. In this paper, an automatic system is provided to segment the left subclavian arteries and left aortic arches from chest MRI (Magnetic Resonance Imaging) images, and then to identify the occlusion of left subclavian artery based on the gray-levels of the extracted left subclavian artery and left aortic arch. Experimental results show that the system obtains the accuracy rate<jats:bold><jats:italic>97.33%<\/jats:italic><\/jats:bold>of detecting the occlusion of left subclavian artery. The other task in this paper is to explore the relationship between stent\/vascular diameter ratio and restenosis of left subclavian artery after stenting. 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