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Magnetic Resonance Imaging (MRI) is widely used for the detection of prostate cancer due to which it is an open area of research. The proposed method uses deep learning framework for the detection of prostate cancer using the concept of Gleason grading of the historical images. A3D convolutional neural network has been used to observe the affected region and predicting the affected region with the help of Epithelial and the Gleason grading network. The proposed model has performed the state-of-art while detecting epithelial and the Gleason score simultaneously. The performance has been measured by considering all the slices of MRI, volumes of MRI with the test fold, and segmenting prostate cancer with help of Endorectal Coil for collecting the images of MRI of the prostate 3D CNN network. Experimentally, it was observed that the proposed deep learning approach has achieved overall specificity of 85% with an accuracy of 87% and sensitivity 89% over the patient-level for the different targeted MRI images of the challenge of the SPIE-AAPM-NCI Prostate dataset.<\/jats:p>","DOI":"10.1007\/s11042-023-15793-0","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T07:02:36Z","timestamp":1688108556000},"page":"14173-14187","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["A novel deep learning-based technique for detecting  prostate cancer in MRI images"],"prefix":"10.1007","volume":"83","author":[{"given":"Sanjay Kumar","family":"Singh","sequence":"first","affiliation":[]},{"given":"Amit","family":"Sinha","sequence":"additional","affiliation":[]},{"given":"Harikesh","family":"Singh","sequence":"additional","affiliation":[]},{"given":"Aniket","family":"Mahanti","sequence":"additional","affiliation":[]},{"given":"Abhishek","family":"Patel","sequence":"additional","affiliation":[]},{"given":"Shubham","family":"Mahajan","sequence":"additional","affiliation":[]},{"given":"Amit Kant","family":"Pandit","sequence":"additional","affiliation":[]},{"given":"Vijayakumar","family":"Varadarajan","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,6,30]]},"reference":[{"issue":"6","key":"15793_CR1","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1109\/TITB.2012.2201731","volume":"16","author":"Y Artan","year":"2012","unstructured":"Artan Y, Yetik IS (2012) Prostate cancer localization using multiparametric MRI based on semisupervised techniques with automated seed initialization. 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