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When diagnosed correctly and early, the recovery rate of patients increases significantly. Physical methods are not sufficient for diagnosis and classification. The aim of this study is to use a hybrid method that combines different deep learning methods in the classification of melanoma and to investigate the effect of optimizer methods used in deep learning methods on classification performance. In the study, Melanoma detection was carried out from the skin lesions image through a simulation created with the deep learning architectures DenseNet, InceptionV3, ResNet50, InceptionResNetV2 and MobileNet and seven optimizers: SGD, Adam, RmsProp, AdaDelta, AdaGrad, Adamax and Nadam. The results of the study show that SGD has better and more stable performance in terms of convergence rate, training speed and performance than other optimizers. In addition, the momentum parameter added to the structure of the SGD optimizer reduces the oscillation and training time compared to other functions. It was observed that the best melanoma detection among the combined methods was achieved using the DenseNet model and SGD optimizer with a test accuracy of 0.949, test sensitivity 0.9403, and test F score 0.9492.<\/jats:p>","DOI":"10.1007\/s11042-024-19561-6","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T03:36:30Z","timestamp":1718163390000},"page":"13787-13807","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of optimizers functions on detection of Melanoma using transfer learning architectures"],"prefix":"10.1007","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9483-4425","authenticated-orcid":false,"given":"Serhat","family":"K\u0131l\u0131\u00e7arslan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice Aktas","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemal","family":"Adem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esra Kavalc\u0131","family":"Y\u0131lmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"key":"19561_CR1","first-page":"178","volume":"365","author":"JJ Poornimaa","year":"2023","unstructured":"Poornimaa JJ, Anitha J, Henry AP, Hemanth DJ (2023) Melanoma Classification Using Machine Learning Techniques: Design Studies and Intelligence Engineering. 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