{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T21:25:28Z","timestamp":1772832328822,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2008,3,19]],"date-time":"2008-03-19T00:00:00Z","timestamp":1205884800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nat Comput"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1007\/s11047-008-9076-x","type":"journal-article","created":{"date-parts":[[2008,3,18]],"date-time":"2008-03-18T10:18:06Z","timestamp":1205835486000},"page":"335-346","source":"Crossref","is-referenced-by-count":30,"title":["Large-scale DNA memory based on the nested PCR"],"prefix":"10.1007","volume":"7","author":[{"given":"Masahito","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Kashiwamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azuma","family":"Ohuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Furukawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2008,3,19]]},"reference":[{"key":"9076_CR1","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1126\/science.7973651","volume":"266","author":"LM Adleman","year":"1994","unstructured":"Adleman LM (1994) Molecular computation of solutions to combinatorial problems. Science 266:1021\u20131024","journal-title":"Science"},{"key":"9076_CR2","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1126\/science.7725109","volume":"268","author":"EB Baum","year":"1995","unstructured":"Baum EB (1995) Building an associative memory vastly larger than the brain. Science 268:583\u2013585","journal-title":"Science"},{"key":"9076_CR3","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/35106533","volume":"414","author":"Y Benenson","year":"2001","unstructured":"Benenson Y, Paz-Elizur T, Adar R, Keinan E, Livneh Z, Shapiro E (2001) Programmable and autonomous computing machine made of biomolecules. Nature 414:430\u2013434","journal-title":"Nature"},{"key":"9076_CR4","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1126\/science.1069528","volume":"296","author":"RS Braich","year":"2002","unstructured":"Braich RS, Chelyapov N, Johnson C, Rothemund PWK, Adleman L (2002) Solution of a 20-variable 3-SAT problem on a DNA computer. Science 296:499\u2013502","journal-title":"Science"},{"issue":"2","key":"9076_CR5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11047-004-4002-3","volume":"4","author":"J Chen","year":"2005","unstructured":"Chen J, Deaton R, Wang YZ (2005) A DNA-based memory with in vitro learning and associative recall. Nat Comput 4(2):83\u2013101","journal-title":"Nat Comput"},{"key":"9076_CR6","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/21092","volume":"399","author":"CT Clelland","year":"1999","unstructured":"Clelland CT, Risca V, Bancroft C (1999) Hiding message in DNA microdots. Nature 399:533\u2013544","journal-title":"Nature"},{"key":"9076_CR7","unstructured":"Deaton R, Murphy RC, Garzon M, Franceschetti DR, Stevens SE Jr (1999) Good encoding for DNA-based solutions to combinatorial problems. In: Landweber LF, Baum EB (eds) DNA based computers II: DIMACS workshop, June 1996, DIMACS series in discrete mathematics and theoretical computer science 44:247\u2013258"},{"key":"9076_CR8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1620\/tjem.204.109","volume":"204","author":"M Hashiyada","year":"2004","unstructured":"Hashiyada M (2004) Development of biometric DNA ink for authentication security. Tohoku J Exp Med 204:109\u2013117","journal-title":"Tohoku J Exp Med"},{"key":"9076_CR9","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0379-0738(03)00075-6","volume":"133","author":"M Hashiyada","year":"2003","unstructured":"Hashiyada M, Itakura Y, Nagashima T, Nata M, Funayama M (2003) Polymorphism of 17 STRs by multiplex analysis in Japanese population. Forensic Sci Int 133:250\u2013253","journal-title":"Forensic Sci Int"},{"key":"9076_CR10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10207-002-0013-1","volume":"1","author":"Y Itakura","year":"2002","unstructured":"Itakura Y, Hashiyada M, Nagashima T, Tsuji S (2002) Proposal on Personal Identifiers Generated from the STR Information of DNA. Int J Information Security 1:149\u2013160","journal-title":"Int J Information Security"},{"key":"9076_CR11","unstructured":"Kameda A, Kashiwamura S, Yamamoto M, Ohuchi A, Hagiya M (2007) Combining randomness and a high-capacity DNA memory. In: Preliminary proceeding of 13th international meeting on DNA Based computers, pp 261\u2013269"},{"key":"9076_CR12","first-page":"112","volume-title":"DNA8: 8th International workshop on DNA-based computers, Sapporo, Japan, June 2002. Lecture notes in computer science","author":"S Kashiwamura","year":"2003","unstructured":"Kashiwamura S, Yamamoto M, Kameda A, Shiba T, Ohuchi A (2003) Hierarchical DNA memory based on nested PCR. In: Hagiya M, Ohuchi A (eds) DNA8: 8th International workshop on DNA-based computers, Sapporo, Japan, June 2002. Lecture notes in computer science, vol 2568. Springer, Berlin Heidelberg New York, pp 112\u2013123"},{"issue":"6","key":"9076_CR13","first-page":"1446","volume":"E87-A","author":"S Kashiwamura","year":"2004","unstructured":"Kashiwamura S, Kameda A, Yamamoto M, Ohuchi A (2004) Two-step search for DNA sequence design. IEICE TRANSACTIONS on Fundamentals of Electronics, Commun Computer Sci E87-A(6):1446\u20131453","journal-title":"IEICE TRANSACTIONS on Fundamentals of Electronics, Communications and Computer Sciences"},{"key":"9076_CR14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.biosystems.2004.10.007","volume":"80","author":"S Kashiwamura","year":"2005","unstructured":"Kashiwamura S, Yamamoto M, Kameda A, Shiba T, Ohuchi A (2005a) Potential for enlarging DNA memory: the validity of experimental operations of scaled-up nested primer molecular memory. BioSystems 80:99\u2013112","journal-title":"BioSystems"},{"key":"9076_CR15","unstructured":"Kashiwamura S, Yamamoto M, Kameda A, Ohuchi A (2005b) Experimental challenge of scaled-up hierarchical DNA memory expressing a 10,000-address space. In: Preliminary proceeding of 11th international meeting on DNA based computers, p 396"},{"key":"9076_CR16","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1126\/science.7725098","volume":"268","author":"R Lipton","year":"1995","unstructured":"Lipton R (1995) DNA solution of hard combinatorial problems. Science 268:542\u2013545","journal-title":"Science"},{"key":"9076_CR17","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/bioinformatics\/15.6.440","volume":"15","author":"LB Lyngso","year":"1999","unstructured":"Lyngso LB, Zuker M, Pedersen CN (1999) Fast evaluation of internal loops in RNA secondary structure prediction. Bioinformatics 15:440\u2013445","journal-title":"Bioinformatics"},{"key":"9076_CR18","doi-asserted-by":"crossref","unstructured":"McPherson MJ, Hames BD, Taylor GR (1995a) PCR: A practical approach. Oxford University Press","DOI":"10.1093\/oso\/9780199634255.001.0001"},{"key":"9076_CR19","doi-asserted-by":"crossref","unstructured":"McPherson MJ, Hames BD, Taylor GR (1995b) PCR2: A practical approach. Oxford University Press","DOI":"10.1093\/oso\/9780199634255.001.0001"},{"key":"9076_CR20","doi-asserted-by":"crossref","unstructured":"Neel A, Garzon MH, Penumatsa P (2004) Improving the quality of semantic retrieval in DNA-based memories with learning. In: KES 2004: 8th Internaltional conference, Wellington, New Zealand, September 20\u201325 2004, Lecture notes in computer science, vol 3213. Springer, Berlin Heidelberg, New York, pp 18\u201324","DOI":"10.1007\/978-3-540-30132-5_7"},{"key":"9076_CR21","first-page":"231","volume-title":"DNA 7: 7th International workshop on DNA-based computers, Tampa, FL, USA, June 2001. Lecture notes in computer science","author":"JH Reif","year":"2002","unstructured":"Reif JH, LaBean TH, Pirrung M, Rana VS, Guo B, Kingsford C, Wickham GS (2002) Experimental construction of very large scale dna databases with associative search capability. In: Jonoska N, Seeman NC (eds) DNA 7: 7th International workshop on DNA-based computers, Tampa, FL, USA, June 2001. Lecture notes in computer science, vol 2340. Springer, Berlin, Heidelberg, New York, pp 231\u2013247"},{"key":"9076_CR22","doi-asserted-by":"crossref","first-page":"3555","DOI":"10.1021\/bi951907q","volume":"35","author":"J SantaLucia","year":"1996","unstructured":"SantaLucia J, Allawi HT, Seneviratne PA (1996) Improved nearest-neighbor parameters for predicting DNA duplex stability. Biochemistry 35:3555\u20133562","journal-title":"Biochemistry"},{"key":"9076_CR23","doi-asserted-by":"crossref","first-page":"4501","DOI":"10.1093\/nar\/24.22.4501","volume":"24","author":"N Sugimoto","year":"1996","unstructured":"Sugimoto N, Nakano S, Yoneyama M, Honda K (1996) Improved thermodynamic parameters and helix initiation factor to predict stability of DNA duplexes. Nucl Acid Res 24:4501\u20134505","journal-title":"Nucl Acid Res"},{"key":"9076_CR24","doi-asserted-by":"crossref","unstructured":"Tanaka F, Kameda A, Yamamoto M, Ohuchi A (2005) Design of nucleic acid sequences for DNA computing based on a thermodynamic approach. Nucl Acid Res 33:903\u2013911","DOI":"10.1093\/nar\/gki235"},{"key":"9076_CR25","first-page":"229","volume-title":"DNA8: 8th international workshop on DNA-based computers, Sapporo, Japan, June 2002. Lecture notes in computer science","author":"DC Tulpan","year":"2003","unstructured":"Tulpan DC, Hoos HH, Condon A (2003) Stochastic local search algorithms for DNA word design. In: Hagiya M, Ohuchi A (eds) DNA8: 8th international workshop on DNA-based computers, Sapporo, Japan, June 2002. Lecture notes in computer science, vol 2568. Springer, Berlin, Heidelberg, New York, pp 229\u2013241"},{"issue":"1","key":"9076_CR26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1145\/602421.602426","volume":"46","author":"PC Wong","year":"2003","unstructured":"Wong PC, Wong KK, Foote H (2003) Organic data memory using the DNA approach. Commun ACM 46(1):95\u201398","journal-title":"Commun ACM"},{"key":"9076_CR27","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/nar\/9.1.133","volume":"9","author":"M Zuker","year":"1981","unstructured":"Zuker M, Stiegler P (1981) Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information. Nucl Acid Res 9:133\u2013148","journal-title":"Nucl Acid Res"}],"container-title":["Natural Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11047-008-9076-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11047-008-9076-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11047-008-9076-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T22:06:15Z","timestamp":1708725975000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11047-008-9076-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,19]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["9076"],"URL":"https:\/\/doi.org\/10.1007\/s11047-008-9076-x","relation":{},"ISSN":["1567-7818","1572-9796"],"issn-type":[{"value":"1567-7818","type":"print"},{"value":"1572-9796","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,19]]}}}