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In order to plan an efficient path that allows the vehicle to be autonomously navigated in cluttered environments, the path planning problem is solved as a multi-objective optimization problem. First, the vehicle perception is fully achieved by means of inertial measurement unit (IMU), wheels odometry, and light detection and ranging (LiDAR). In order to compensate the sensors drift to achieve more reliable data and improve the localization estimation and corrections, data fusion between the outputs of wheels odometry, LiDAR, and IMU is made through extended Kalman filter (EKF). Then, TLBO is proposed and applied to determine the optimum online path, where the objectives are to find the shortest path to reach the target destination, and to maximize the path smoothness, while avoiding the surrounding obstacles, and taking into account the vehicle dynamic and algebraic constraints. To check the performance of the proposed TLBO algorithm, it is compared in simulation to genetic algorithm (GA), particle swarm optimization (PSO), and a hybrid GA\u2013PSO algorithm. Finally, real-time experiments based on robot operating system (ROS) implementation are conducted to validate the effectiveness of the proposed path planning algorithm.<\/jats:p>","DOI":"10.1007\/s11370-022-00429-3","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T04:02:38Z","timestamp":1656302558000},"page":"381-398","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Real-time path planning for autonomous vehicle based on teaching\u2013learning-based optimization"],"prefix":"10.1007","volume":"15","author":[{"given":"Ahmed D.","family":"Sabiha","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1968-4345","authenticated-orcid":false,"given":"Mohamed A.","family":"Kamel","sequence":"additional","affiliation":[]},{"given":"Ehab","family":"Said","sequence":"additional","affiliation":[]},{"given":"Wessam M.","family":"Hussein","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"issue":"9","key":"429_CR1","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.5897\/IJPS11.1745","volume":"7","author":"P Raja","year":"2012","unstructured":"Raja P, Pugazhenthi S (2012) Optimal path planning of mobile robots: A review. 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