{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T09:30:33Z","timestamp":1742635833183},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,11,26]],"date-time":"2011-11-26T00:00:00Z","timestamp":1322265600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1007\/s11517-011-0844-x","type":"journal-article","created":{"date-parts":[[2011,11,25]],"date-time":"2011-11-25T17:47:48Z","timestamp":1322243268000},"page":"33-42","source":"Crossref","is-referenced-by-count":1,"title":["Strategy for NSAID administration to aspirin-intolerant asthmatics in combination with PGE2 analogue: a theoretical approach"],"prefix":"10.1007","volume":"50","author":[{"given":"A.","family":"Dobovi\u0161ek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fajmut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Brumen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,11,26]]},"reference":[{"key":"844_CR1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.mvr.2005.01.007","volume":"69","author":"N Bogatcheva","year":"2005","unstructured":"Bogatcheva N, Sergeeva M, Dudek S, Verin A (2005) Arachidonic acid cascade in endothelial pathobiology. Microvasc Res 69:107\u2013127","journal-title":"Microvasc Res"},{"key":"844_CR2","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1172\/JCI620","volume":"101","author":"AS Cowburn","year":"1998","unstructured":"Cowburn AS, Sladek K, Soja A, Adamek L, Nizankowska E, Szczeklik A, Lam BK, Penrose J, Austen KF, Holgate ST, Sampson AP (1998) Over-expression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. J Clin Invest 101:834\u2013846","journal-title":"J Clin Invest"},{"key":"844_CR3","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10928-011-9192-6","volume":"38","author":"A Dobovi\u0161ek","year":"2011","unstructured":"Dobovi\u0161ek A, Fajmut A, Brumen M (2011) Role of expression of prostaglandin synthases 1 and 2 and leukotriene C4 synthase in aspirin-intolerant asthma: a theoretical study. J Pharmacokinet Pharmacodyn 38:261\u2013278","journal-title":"J Pharmacokinet Pharmacodyn"},{"key":"844_CR4","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1164\/ajrccm.159.1.9804030","volume":"159","author":"GM Gauvreau","year":"1999","unstructured":"Gauvreau GM, Watson RM, O\u2019Byrne PM (1999) Protective effects of inhaled PGE2 on allergen-induced airway responses and airway inflammation. Am J Respir Crit Care Med 159:31\u201336","journal-title":"Am J Respir Crit Care Med"},{"key":"844_CR5","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1046\/j.1432-1327.1999.00785.x","volume":"265","author":"M Gonchar","year":"1999","unstructured":"Gonchar M, Sergeeva M, Mevkh A, Varfolomeyev S (1999) Kinetics of prostanoid synthesis by macrophages is regulated by arachidonic acid sources. Eur J Biochem 265:779\u2013787","journal-title":"Eur J Biochem"},{"key":"844_CR6","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0005-2760(98)00002-2","volume":"1391","author":"N Gupta","year":"1998","unstructured":"Gupta N, Gresser M, Ford-Hutchinson A (1998) Kinetic mechanism of glutathione conjugation to leukotriene A4 by leukotriene C4 synthase. Biochim Biophys Acta 1391:157\u2013168","journal-title":"Biochim Biophys Acta"},{"key":"844_CR7","doi-asserted-by":"crossref","first-page":"139","DOI":"10.4049\/jimmunol.170.1.139","volume":"170","author":"H Harizi","year":"2003","unstructured":"Harizi H, Juzan M, Moreau J-F, Gualde N (2003) Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B4 production from dendritic cells via an IL-10-dependent mechanism. J Immunol 170:139\u2013146","journal-title":"J Immunol"},{"key":"844_CR8","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1164\/ajrccm.162.2.9904038","volume":"162","author":"TV Hartert","year":"2000","unstructured":"Hartert TV, Dworski RT, Mellen BG, Oates JA, Murray JJ, Sheller JR (2000) Prostaglandin E2 decreases allergen-stimulated release of prostaglandin D2 in airways of subjects with asthma. Am J Respir Crit Care Med 162:637\u2013640","journal-title":"Am J Respir Crit Care Med"},{"key":"844_CR9","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/978-1-4613-1161-4_5","volume-title":"The regulation of cellular systems","author":"R Heinrich","year":"1996","unstructured":"Heinrich R, Schuster S (1996) The regulation of cellular systems. Chapman & Hall, New York, pp 138\u2013153"},{"key":"844_CR10","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/3527603603","volume-title":"Systems biology in practice. Concepts, implementation and application","author":"E Klipp","year":"2005","unstructured":"Klipp E, Herwig R, Kowald A, Wierling C, Lehrach H (2005) Systems biology in practice. Concepts, implementation and application. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, pp 174\u2013196"},{"key":"844_CR11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.bpc.2010.02.006","volume":"148","author":"M Marhl","year":"2010","unstructured":"Marhl M, Gosak M, Perc M, Roux E (2010) Importance of cell variability for calcium signaling in rat airway myocytes. Biophys Chem 148:42\u201350","journal-title":"Biophys Chem"},{"key":"844_CR12","first-page":"434S","volume":"7","author":"L Mastalerz","year":"1994","unstructured":"Mastalerz L, Nizankowska E, Sladek K, Szczeklik A (1994) Protective effects of prostaglandin E2 on airway obstruction induced by aspirin in aspirin-intolerant asthmatics. Eur Respir J 7:434S","journal-title":"Eur Respir J"},{"key":"844_CR13","doi-asserted-by":"crossref","first-page":"R181","DOI":"10.1186\/ar2092","volume":"8","author":"K Maxis","year":"2006","unstructured":"Maxis K, Delalandre A, Martel-Pelletier J, Pelletier JP, Duval N, Lajeunesse D (2006) The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein. Arthritis Res Ther 8:R181","journal-title":"Arthritis Res Ther"},{"key":"844_CR14","doi-asserted-by":"crossref","first-page":"6610","DOI":"10.1016\/S0021-9258(18)53294-4","volume":"268","author":"E Meade","year":"1993","unstructured":"Meade E, Smith W, DeWitt D (1993) Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J Biol Chem 268:6610\u20136614","journal-title":"J Biol Chem"},{"key":"844_CR15","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1164\/ajrccm.149.5.8173753","volume":"149","author":"E Melillo","year":"1994","unstructured":"Melillo E, Woolley KL, Manning PJ, Watson RM, O\u2019Byrne PM (1994) Effect of inhaled PGE2 on exercise-induced bronchoconstriction in asthmatic subjects. Am J Respir Crit Care Med 149:1138\u20131141","journal-title":"Am J Respir Crit Care Med"},{"key":"844_CR16","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1164\/ajrccm.160.1.9808048","volume":"160","author":"C Picado","year":"1999","unstructured":"Picado C, Fernandez-Morata JC, Juan M, Roca-Ferrer J, Fuentes M, Xaubet A, Mullol J (1999) Cyclooxygenase-2 mRNA is down expressed in nasal polyps from aspirin-sensitive asthmatics. Am J Respir Crit Care Med 160:291\u2013296","journal-title":"Am J Respir Crit Care Med"},{"key":"844_CR17","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1067\/mai.2003.1491","volume":"111","author":"M Pierzchalska","year":"2003","unstructured":"Pierzchalska M, Szabo Z, Sanak M, Soja J, Szczeklik A (2003) Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin induced asthma. J Allergy Clin Immunol 111:1041\u20131048","journal-title":"J Allergy Clin Immunol"},{"key":"844_CR18","first-page":"153","volume":"15","author":"A Rosado","year":"2000","unstructured":"Rosado A, Vives R, Gonz\u00e1lez R, Poza P, Rodr\u00edguez J (2000) Intolerance to non-steroidal anti inflammatory drugs with respiratory reaction: clinical and diagnostic features. Alergol Inmunol Clin 15:153\u2013159","journal-title":"Alergol Inmunol Clin"},{"key":"844_CR19","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.mcna.2010.03.005","volume":"94","author":"M S\u00e1nchez-Borges","year":"2010","unstructured":"S\u00e1nchez-Borges M (2010) NSAID hypersensitivity (Respiratory, cutaneous, and generalized anaphylactic symptoms). Med Clin North Am 94:853\u2013864","journal-title":"Med Clin North Am"},{"key":"844_CR20","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1136\/thx.51.9.919","volume":"51","author":"D Sch\u00e4fer","year":"1996","unstructured":"Sch\u00e4fer D, Lindenthal U, Wagner M, B\u00f6lcskei PL, Baenkler HW (1996) Effect of prostaglandin E2 on eicosanoid release by human bronchial biopsy specimens from normal and inflamed mucosa. Thorax 51:919\u2013923","journal-title":"Thorax"},{"key":"844_CR21","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1183\/09031936.99.13363899","volume":"13","author":"D Sch\u00e4fer","year":"1999","unstructured":"Sch\u00e4fer D, Schmid M, G\u00f6de UC, Baenkler HW (1999) Dynamics of eicosanoids in peripheral blood cells during provocation in aspirin-intolerant asthmatics. Eur Respir J 13:638\u2013646","journal-title":"Eur Respir J"},{"key":"844_CR22","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1164\/ajrccm.153.2.8564100","volume":"153","author":"P Sestini","year":"1996","unstructured":"Sestini P, Armetti L, Gambaro G, Pieroni M, Refini RM, Sala A, Vaghi A, Folco GC, Bianco S, Robuschi M (1996) Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma. Am J Respir Crit Care Med 153:572\u2013575","journal-title":"Am J Respir Crit Care Med"},{"key":"844_CR23","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0091-6749(95)70290-3","volume":"96","author":"RA Setipane","year":"1995","unstructured":"Setipane RA, Schrank PJ, Simon RA, Mathison DA, Christiansen SC, Stevenson DD (1995) Prevalence of cross-sensitivity with acetaminophen in aspirin-sensitive asthmatic subjects. J Allergy Clin Immunol 96:480\u2013485","journal-title":"J Allergy Clin Immunol"},{"key":"844_CR24","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/sj.bjp.0703780","volume":"132","author":"H Setoguchi","year":"2001","unstructured":"Setoguchi H, Nishimura J, Hirano K, Takahashi S, Kanaide H (2001) Leukotriene C4 enhances the contraction of porcine tracheal smooth muscle trough the activation of Y-27632, a rho kinase inhibitor, sensitive pathway. Br J Pharmacol 132:111\u2013118","journal-title":"Br J Pharmacol"},{"key":"844_CR25","doi-asserted-by":"crossref","first-page":"5801","DOI":"10.1074\/jbc.273.10.5801","volume":"273","author":"O-Y So","year":"1998","unstructured":"So O-Y, Scarafia LE, Mak AY, Callan OH, Swinney DC (1998) The dynamics of prostaglandin H synthases. Study with prostaglandin H-synthase 2Y355F unmask mechanisms of time-dependent inhibition and allosteric activation. J Biol Chem 273:5801\u20135807","journal-title":"J Biol Chem"},{"key":"844_CR26","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.jaci.2006.07.024","volume":"118","author":"D Stevenson","year":"2006","unstructured":"Stevenson D, Szczeklik A (2006) Clinical and pathologic perspectives on aspirin sensitivity and asthma. J Allergy Clin Immunol 118:773\u2013786","journal-title":"J Allergy Clin Immunol"},{"key":"844_CR27","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0091-6749(99)70106-5","volume":"104","author":"A Szczeklik","year":"1999","unstructured":"Szczeklik A, Stevenson D (1999) Aspirin-induced asthma: advances in pathogenesis and management. J Allergy Clin Immunol 104:5\u201313","journal-title":"J Allergy Clin Immunol"},{"key":"844_CR28","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1365-2222.2001.01075.x","volume":"31","author":"A Szczeklik","year":"2001","unstructured":"Szczeklik A, Nizankowska E, Bochenek G, Nagraba K, Mejza F, Swierczynska M (2001) Safety of specific COX-2 inhibitor in aspirin-induced asthma. Clin Exp Allergy 31:219\u2013225","journal-title":"Clin Exp Allergy"},{"key":"844_CR29","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/BF00315552","volume":"44","author":"U T\u00e4uber","year":"1993","unstructured":"T\u00e4uber U, Brudny\u2013Kl\u00f6ppel M, Jakobs U, Madetzki C, Mahler M (1993) Pharmacokinetics of nocloprost in human volunteers and its relation to dose. Eur J Clin Pharmacol 44:497\u2013500","journal-title":"Eur J Clin Pharmacol"},{"key":"844_CR30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1096\/fasebj.1.2.3111928","volume":"1","author":"J Vane","year":"1987","unstructured":"Vane J, Botting R (1987) Inflammation and the mechanism of action of anti inflammatory drugs. FASEB J 1:89\u201396","journal-title":"FASEB J"},{"key":"844_CR31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1710-1492-4-2-75","volume":"4","author":"M Varghese","year":"2008","unstructured":"Varghese M, Lockey RF (2008) Aspirin-exacerbated asthma. Allergy Asthma Clin Immunol 4:75\u201383","journal-title":"Allergy Asthma Clin Immunol"}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-011-0844-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11517-011-0844-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-011-0844-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T00:59:03Z","timestamp":1639789143000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11517-011-0844-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,26]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["844"],"URL":"https:\/\/doi.org\/10.1007\/s11517-011-0844-x","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,11,26]]}}}