{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T02:25:17Z","timestamp":1772677517893,"version":"3.50.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:00:00Z","timestamp":1540339200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1007\/s11517-018-1904-2","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T05:32:22Z","timestamp":1540359142000},"page":"715-729","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Correlation between geometric parameters of the left coronary artery and hemodynamic descriptors of atherosclerosis: FSI and statistical study"],"prefix":"10.1007","volume":"57","author":[{"given":"N.","family":"Pinho","sequence":"first","affiliation":[]},{"given":"C. F.","family":"Castro","sequence":"additional","affiliation":[]},{"given":"C. C.","family":"Ant\u00f3nio","sequence":"additional","affiliation":[]},{"given":"N.","family":"Bettencourt","sequence":"additional","affiliation":[]},{"given":"L. C.","family":"Sousa","sequence":"additional","affiliation":[]},{"given":"S. I. S.","family":"Pinto","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"1904_CR1","unstructured":"(2010) WHO | The Atlas of Heart Disease and Stroke. WHO"},{"key":"1904_CR2","doi-asserted-by":"publisher","first-page":"1852","DOI":"10.1161\/CIRCRESAHA.114.302721","volume":"114","author":"JF Bentzon","year":"2014","unstructured":"Bentzon JF, Otsuka F, Virmani R, Falk E (2014) Mechanisms of plaque formation and rupture. Circ Res 114:1852\u20131866. \n                    https:\/\/doi.org\/10.1161\/CIRCRESAHA.114.302721","journal-title":"Circ Res"},{"key":"1904_CR3","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1161\/01.CIR.97.18.1837","volume":"97","author":"PWF Wilson","year":"1998","unstructured":"Wilson PWF, D\u2019Agostino RB, Levy D et al (1998) Prediction of coronary heart disease using risk factor categories. Circulation 97:1837\u20131847. \n                    https:\/\/doi.org\/10.1161\/01.CIR.97.18.1837","journal-title":"Circulation"},{"key":"1904_CR4","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1007\/s10439-014-1056-y","volume":"43","author":"M Malv\u00e8","year":"2014","unstructured":"Malv\u00e8 M, Gharib AM, Yazdani SK et al (2014) Tortuosity of coronary bifurcation as a potential local risk factor for atherosclerosis: CFD steady state study based on in vivo dynamic CT measurements. Ann Biomed Eng 43:82\u201393. \n                    https:\/\/doi.org\/10.1007\/s10439-014-1056-y","journal-title":"Ann Biomed Eng"},{"key":"1904_CR5","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1038\/2231159a0","volume":"223","author":"CG Caro","year":"1969","unstructured":"Caro CG, Fitz-Gerald JM, Schroter RC (1969) Arterial wall shear and distribution of early atheroma in man. Nature 223:1159\u20131161. \n                    https:\/\/doi.org\/10.1038\/2231159a0","journal-title":"Nature"},{"key":"1904_CR6","doi-asserted-by":"publisher","DOI":"10.4015\/S1016237214500136","volume":"26","author":"A Karimi","year":"2014","unstructured":"Karimi A, Navidbakhsh M, Shojaei A et al (2014) Study of plaque vulnerability in coronary artery using Mooney\u2013Rivlin model: a combination of finite element and experimental method. Biomed Eng Appl Basis Commun 26:1450013. \n                    https:\/\/doi.org\/10.4015\/S1016237214500136","journal-title":"Biomed Eng Appl Basis Commun"},{"key":"1904_CR7","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1177\/0954411912461239","volume":"227","author":"A Karimi","year":"2012","unstructured":"Karimi A, Navidbakhsh M, Faghihi S et al (2012) A finite element investigation on plaque vulnerability in realistic healthy and atherosclerotic human coronary arteries. Proc Inst Mech Eng H 227:148\u2013161. \n                    https:\/\/doi.org\/10.1177\/0954411912461239","journal-title":"Proc Inst Mech Eng H"},{"key":"1904_CR8","doi-asserted-by":"publisher","unstructured":"Chaichana T, Sun Z, Jewkes J (2012) Computational fluid dynamics analysis of the effect of plaques in the left coronary artery. Comput Math Methods Med 2012. \n                    https:\/\/doi.org\/10.1155\/2012\/504367","DOI":"10.1155\/2012\/504367"},{"key":"1904_CR9","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1016\/j.jbiomech.2011.04.033","volume":"44","author":"T Chaichana","year":"2011","unstructured":"Chaichana T, Sun Z, Jewkes J (2011) Computation of hemodynamics in the left coronary artery with variable angulations. J Biomech 44:1869\u20131878. \n                    https:\/\/doi.org\/10.1016\/j.jbiomech.2011.04.033","journal-title":"J Biomech"},{"key":"1904_CR10","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1080\/10255842.2016.1149575","volume":"19","author":"S Pinto","year":"2016","unstructured":"Pinto S, Campos JBLM (2016) Numerical study of wall shear stress-based descriptors in the human left coronary artery. Comput Methods Biomech Biomed Engin 19:1443\u20131455. \n                    https:\/\/doi.org\/10.1080\/10255842.2016.1149575","journal-title":"Comput Methods Biomech Biomed Engin"},{"key":"1904_CR11","unstructured":"Costa ED (2016) Hemodynamics in the Left Coronary Artery \u2013 numerical and in vitro approaches. Retrieved from Reposit\u00f3rio Aberto da Universidade do Porto"},{"key":"1904_CR12","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.jtbi.2016.04.038","volume":"402","author":"E Doutel","year":"2016","unstructured":"Doutel E, Pinto SIS, Campos JBLM, Miranda JM (2016) Link between deviations from Murray\u2019s law and occurrence of low wall shear stress regions in the left coronary artery. J Theor Biol 402:89\u201399. \n                    https:\/\/doi.org\/10.1016\/j.jtbi.2016.04.038","journal-title":"J Theor Biol"},{"key":"1904_CR13","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.icheatmasstransfer.2012.04.009","volume":"39","author":"M Malv\u00e8","year":"2012","unstructured":"Malv\u00e8 M, Garc\u00eda A, Ohayon J, Mart\u00ednez MA (2012) Unsteady blood flow and mass transfer of a human left coronary artery bifurcation: FSI vs. CFD. Int Commun Heat Mass Transf 39:745\u2013751. \n                    https:\/\/doi.org\/10.1016\/j.icheatmasstransfer.2012.04.009","journal-title":"Int Commun Heat Mass Transf"},{"key":"1904_CR14","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1080\/10255842.2014.921682","volume":"18","author":"J Dong","year":"2015","unstructured":"Dong J, Sun Z, Inthavong K, Tu J (2015) Fluid\u2013structure interaction analysis of the left coronary artery with variable angulation. Comput Methods Biomech Biomed Engin 18:1500\u20131508. \n                    https:\/\/doi.org\/10.1080\/10255842.2014.921682","journal-title":"Comput Methods Biomech Biomed Engin"},{"key":"1904_CR15","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.medengphy.2017.05.008","volume":"47","author":"B Guerciotti","year":"2017","unstructured":"Guerciotti B, Vergara C, Ippolito S et al (2017) A computational fluid\u2013structure interaction analysis of coronary Y-grafts. Med Eng Phys 47:117\u2013127. \n                    https:\/\/doi.org\/10.1016\/j.medengphy.2017.05.008","journal-title":"Med Eng Phys"},{"key":"1904_CR16","doi-asserted-by":"publisher","first-page":"2260","DOI":"10.1161\/01.ATV.0000095976.40874.E0","volume":"23","author":"H Zhu","year":"2003","unstructured":"Zhu H, Friedman MH (2003) Relationship between the dynamic geometry and wall thickness of a human coronary artery. Arterioscler Thromb Vasc Biol 23:2260\u20132265. \n                    https:\/\/doi.org\/10.1161\/01.ATV.0000095976.40874.E0","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1904_CR17","doi-asserted-by":"publisher","first-page":"2531","DOI":"10.1088\/0031-9155\/52\/9\/013","volume":"52","author":"BM Johnston","year":"2007","unstructured":"Johnston BM, Johnston PR (2007) The relative effects of arterial curvature and lumen diameter on wall shear stress distributions in human right coronary arteries. Phys Med Biol 52:2531\u20132544. \n                    https:\/\/doi.org\/10.1088\/0031-9155\/52\/9\/013","journal-title":"Phys Med Biol"},{"key":"1904_CR18","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1007\/s10439-008-9531-y","volume":"36","author":"H Zakaria","year":"2008","unstructured":"Zakaria H, Robertson AM, Kerber CW (2008) A parametric model for studies of flow in arterial bifurcations. Ann Biomed Eng 36:1515\u20131530. \n                    https:\/\/doi.org\/10.1007\/s10439-008-9531-y","journal-title":"Ann Biomed Eng"},{"key":"1904_CR19","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1007\/s11517-014-1197-z","volume":"52","author":"LC Sousa","year":"2014","unstructured":"Sousa LC, Castro CF, Ant\u00f3nio CC et al (2014) Toward hemodynamic diagnosis of carotid artery stenosis based on ultrasound image data and computational modeling. Med Biol Eng Comput 52:971\u2013983. \n                    https:\/\/doi.org\/10.1007\/s11517-014-1197-z","journal-title":"Med Biol Eng Comput"},{"key":"1904_CR20","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1113\/jphysiol.1955.sp005276","volume":"127","author":"JR Womersley","year":"1955","unstructured":"Womersley JR (1955) Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J Physiol 127:553\u2013563. \n                    https:\/\/doi.org\/10.1113\/jphysiol.1955.sp005276","journal-title":"J Physiol"},{"key":"1904_CR21","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4070\/kcj.2011.41.7.349","volume":"41","author":"CG Park","year":"2011","unstructured":"Park CG, Lee JY (2011) The significance of the J-curve in hypertension and coronary artery diseases. Korean Circ J 41:349\u2013353. \n                    https:\/\/doi.org\/10.4070\/kcj.2011.41.7.349","journal-title":"Korean Circ J"},{"key":"1904_CR22","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1002\/cnm.1231","volume":"25","author":"R Torii","year":"2009","unstructured":"Torii R, Wood NB, Hadjiloizou N et al (2009) Fluid\u2013structure interaction analysis of a patient-specific right coronary artery with physiological velocity and pressure waveforms. Commun Numer Methods Eng 25:565\u2013580. \n                    https:\/\/doi.org\/10.1002\/cnm.1231","journal-title":"Commun Numer Methods Eng"},{"key":"1904_CR23","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.2972","volume":"34","author":"SIS Pinto","year":"2018","unstructured":"Pinto SIS, Campos JBLM, Azevedo E et al (2018) Numerical study on the hemodynamics of patient-specific carotid bifurcation using a new mesh approach. Int J Numer Method Biomed Eng 34:e2972. \n                    https:\/\/doi.org\/10.1002\/cnm.2972","journal-title":"Int J Numer Method Biomed Eng"},{"key":"1904_CR24","doi-asserted-by":"publisher","first-page":"2576","DOI":"10.12659\/MSM.899313","volume":"22","author":"Q Zhang","year":"2016","unstructured":"Zhang Q, Gao B, Chang Y (2016) Effect of different rotational directions of BJUT-II VAD on aortic swirling flow characteristics: a primary computational fluid dynamics study. Med Sci Monit 22:2576\u20132588. \n                    https:\/\/doi.org\/10.12659\/MSM.899313","journal-title":"Med Sci Monit"},{"key":"1904_CR25","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1016\/j.jbiomech.2009.04.010","volume":"42","author":"H Gao","year":"2009","unstructured":"Gao H, Long Q, Graves M et al (2009) Carotid arterial plaque stress analysis using fluid-structure interactive simulation based on in-vivo magnetic resonance images of four patients. J Biomech 42:1416\u20131423. \n                    https:\/\/doi.org\/10.1016\/j.jbiomech.2009.04.010","journal-title":"J Biomech"},{"key":"1904_CR26","unstructured":"Ansys\u00ae Academic Research 15.0 (2013) ANSYS fluent tutorial guide. Help Syst:1067"},{"key":"1904_CR27","first-page":"495","volume-title":"Patient-specific study of a Stenosed carotid artery bifurcation using fluid\u2013structure interactive simulation BT - VipIMAGE 2017: proceedings of the VI ECCOMAS thematic conference on computational vision and medical image processing Porto, Portugal, Octob","author":"N Pinho","year":"2018","unstructured":"Pinho N, Bento M, Sousa LC et al (2018) In: Natal Jorge RM, Tavares JMRS (eds) Patient-specific study of a Stenosed carotid artery bifurcation using fluid\u2013structure interactive simulation BT - VipIMAGE 2017: proceedings of the VI ECCOMAS thematic conference on computational vision and medical image processing Porto, Portugal, Octob. Springer, Cham, pp 495\u2013503"},{"key":"1904_CR28","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.1001\/jama.282.21.2035","volume":"282","author":"M AM","year":"1999","unstructured":"AM M, SL A, Izumo S (1999) Hemodynamic shear stress and its role in atherosclerosis. JAMA 282:2035\u20132042","journal-title":"JAMA"},{"key":"1904_CR29","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1146\/annurev.bioeng.5.040202.121529","volume":"5","author":"JM Tarbell","year":"2003","unstructured":"Tarbell JM (2003) Mass transport in arteries and the localization of atherosclerosis. Annu Rev Biomed Eng 5:79\u2013118. \n                    https:\/\/doi.org\/10.1146\/annurev.bioeng.5.040202.121529","journal-title":"Annu Rev Biomed Eng"},{"key":"1904_CR30","unstructured":"Soulis J V, Fytanidis DK (2011) Oscillating shear index , wall shear stress and low density lipoprotein accumulation in human RCAs. 3rd Micro and Nano Flows Conference, Thessaloniki, Greece, 22\u201324 August 2011"},{"key":"1904_CR31","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1115\/1.2795948","volume":"118","author":"X He","year":"1996","unstructured":"He X, He X, Ku DN, Ku DN (1996) Pulsatile flow in the human left coronary artery bifurcation: average conditions. J Biomech Eng 118:74\u201382","journal-title":"J Biomech Eng"},{"key":"1904_CR32","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1007\/s10237-016-0853-7","volume":"16","author":"A Arzani","year":"2017","unstructured":"Arzani A, Gambaruto AM, Chen G, Shadden SC (2017) Wall shear stress exposure time: a Lagrangian measure of near-wall stagnation and concentration in cardiovascular flows. Biomech Model Mechanobiol 16:787\u2013803. \n                    https:\/\/doi.org\/10.1007\/s10237-016-0853-7","journal-title":"Biomech Model Mechanobiol"},{"key":"1904_CR33","first-page":"1","volume-title":"Lima R","author":"D Gallo","year":"2014","unstructured":"Gallo D, Isu G, Massai D et al (2014) A survey of quantitative descriptors of arterial flows BT - visualization and simulation of complex flows in biomedical engineering. In: Imai Y, Ishikawa T, Oliveira MSN (eds) Lima R. Springer, Dordrecht, pp 1\u201324"},{"key":"1904_CR34","doi-asserted-by":"publisher","DOI":"10.1115\/1.3127252","volume":"131","author":"S-W Lee","year":"2009","unstructured":"Lee S-W, Antiga L, Steinman DA (2009) Correlations among indicators of disturbed flow at the normal carotid bifurcation. J Biomech Eng 131:061013. \n                    https:\/\/doi.org\/10.1115\/1.3127252","journal-title":"J Biomech Eng"},{"key":"1904_CR35","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1002\/mrm.24802","volume":"71","author":"R Lorenz","year":"2014","unstructured":"Lorenz R, Bock J, Barker AJ et al (2014) 4D flow magnetic resonance imaging in bicuspid aortic valve disease demonstrates altered distribution of aortic blood flow helicity. Magn Reson Med 71:1542\u20131553. \n                    https:\/\/doi.org\/10.1002\/mrm.24802","journal-title":"Magn Reson Med"},{"key":"1904_CR36","volume-title":"Fundamentals of fluid mechanics","author":"BR Munson","year":"2013","unstructured":"Munson BR, Okiishi TH, Huebsch WW, Rothmayer AP (2013) Fundamentals of fluid mechanics. Wiley, Hoboken"},{"key":"1904_CR37","doi-asserted-by":"publisher","first-page":"21","DOI":"10.4314\/aipm.v6i1.64038","volume":"6","author":"T Dahiru","year":"2011","unstructured":"Dahiru T (2011) P-value, a true test of statistical significance? A cautionary note. Ann Ibadan Postgrad Med 6:21\u201326. \n                    https:\/\/doi.org\/10.4314\/aipm.v6i1.64038","journal-title":"Ann Ibadan Postgrad Med"},{"key":"1904_CR38","unstructured":"Evans JD (1995) Straightforward statistics for the behavioral science. Brooks\/Cole, Pacific Grove"},{"key":"1904_CR39","doi-asserted-by":"publisher","first-page":"379","DOI":"10.5114\/kitp.2015.56795","volume":"12","author":"J Wasilewski","year":"2015","unstructured":"Wasilewski J, Niedziela J, Osadnik T et al (2015) Predominant location of coronary artery atherosclerosis in the left anterior descending artery. The impact of septal perforators and the myocardial bridging effect. Kardiochir Torakochirurgia Pol 12:379\u2013385. \n                    https:\/\/doi.org\/10.5114\/kitp.2015.56795","journal-title":"Kardiochir Torakochirurgia Pol"}],"container-title":["Medical & Biological Engineering & Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11517-018-1904-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-018-1904-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-018-1904-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,24]],"date-time":"2019-10-24T00:08:06Z","timestamp":1571875686000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11517-018-1904-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["1904"],"URL":"https:\/\/doi.org\/10.1007\/s11517-018-1904-2","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,24]]},"assertion":[{"value":"4 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 October 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}