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This study aimed to investigate whether the use of infrared thermography and measurement of temperature profiles along the hand fingers could detect the inflammation and improve the diagnostic accuracy of the cold provocation test (0 \u00b0C for 5 s) and rewarming test (23 \u00b0C for180 s) in RA patients. Thirty RA patients (mean age = 49.5 years, standard deviation = 13.0 years) and 22 controls (mean age = 49.8 years, standard deviation = 7.5 years) were studied. Outcomes were the minimal and maximal: baseline temperature (<jats:italic>T1<\/jats:italic>), the temperature post-cooling (<jats:italic>T2<\/jats:italic>), the temperature post-rewarming (<jats:italic>T3<\/jats:italic>), and the <jats:italic>Tmax-Tmin<\/jats:italic> along the axis of each finger. The statistical significance was observed for the thumb, index finger, middle finger, and ring finger post-cooling and post-rewarming. Receiver operating characteristics (ROC) analysis to distinguish between the two groups revealed that for the thumb, index finger, middle finger, and ring finger, the area under the ROC curve was statistically significantly (<jats:italic>p<\/jats:italic> &lt; 0.05) post-cooling. The cold provocation test used in this study discriminates between RA patients and controls and detects an inflammation in RA patients by the measurement of temperature profiles along the fingers using an infrared camera.<\/jats:p>","DOI":"10.1007\/s11517-019-02055-1","type":"journal-article","created":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T17:03:01Z","timestamp":1572714181000},"page":"2629-2639","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Detection of inflammation from finger temperature profile in rheumatoid arthritis"],"prefix":"10.1007","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8607-7129","authenticated-orcid":false,"given":"J.","family":"Pauk","sequence":"first","affiliation":[]},{"given":"M.","family":"Ihnatouski","sequence":"additional","affiliation":[]},{"given":"A.","family":"Wasilewska","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2019,11,2]]},"reference":[{"key":"2055_CR1","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.3899\/jrheum.100173","volume":"37","author":"TR Mikuls","year":"2010","unstructured":"Mikuls TR (2010) Help stop tooth decay...and prevent RA? 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