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In order to validate numerical methods and codes used for biomedical flow computations, the US Food and Drug Administration (FDA) established an experimental benchmark, which was a pipe with gradual contraction and sudden expansion representing a nozzle. The experimental results for various Reynolds numbers ranging from 500 to 6500 were publicly released. Previous and recent computational investigations of flow in the FDA nozzle found limitations in various CFD approaches and some even questioned the adequacy of the benchmark itself. This communication reports the results of a lattice Boltzmann method (LBM) \u2013 based direct numerical simulation (DNS) approach applied to the FDA nozzle benchmark for transitional cases of Reynolds numbers 2000 and 3500. The goal is to evaluate if a simple<jats:italic>off the shelf<\/jats:italic>LBM would predict the experimental results without the use of complex models or synthetic turbulence at the inflow. LBM computations with various spatial and temporal resolutions are performed\u2014in the extremities of 45 million to 2.88 billion lattice cells\u2014executed respectively on 32 CPU cores of a desktop to more than 300,000 cores of a modern supercomputer to explore and characterize miniscule flow details and quantify Kolmogorov scales. The LBM simulations transition to turbulence at a Reynolds number 2000 like the FDA\u2019s experiments and acceptable agreement in<jats:italic>jet breakdown locations, average velocity, shear stress<\/jats:italic>, and<jats:italic>pressure<\/jats:italic>is found for both the Reynolds numbers.<\/jats:p>","DOI":"10.1007\/s11517-020-02188-8","type":"journal-article","created":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T23:02:47Z","timestamp":1591570967000},"page":"1817-1830","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime"],"prefix":"10.1007","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6540-9304","authenticated-orcid":false,"given":"Kartik","family":"Jain","sequence":"first","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2020,6,7]]},"reference":[{"issue":"1","key":"2188_CR1","doi-asserted-by":"publisher","first-page":"e3150","DOI":"10.1002\/cnm.3150","volume":"35","author":"AW Bergersen","year":"2019","unstructured":"Bergersen AW, Mortensen M, Valen-Sendstad K (2019) The FDA nozzle benchmark: in theory there is no difference between theory and practice, but in practice there is. 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