{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T15:54:26Z","timestamp":1772553266847,"version":"3.50.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100010909","name":"Young Scientists Fund","doi-asserted-by":"publisher","award":["62001153"],"award-info":[{"award-number":["62001153"]}],"id":[{"id":"10.13039\/501100010909","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s11517-022-02693-y","type":"journal-article","created":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T04:03:02Z","timestamp":1666670582000},"page":"3655-3664","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Impact of repetitive transcranial magnetic stimulation on the directed connectivity of autism EEG signals: a pilot study"],"prefix":"10.1007","volume":"60","author":[{"given":"Jiannan","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel F.","family":"Casanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Estate M.","family":"Sokhadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinling","family":"Geng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"2693_CR1","doi-asserted-by":"crossref","unstructured":"Roehr B (2013) American Psychiatric Association explains DSM-5. Bmj-Brit Med J 346. ARTN f359110.1136\/bmj.f3591","DOI":"10.1136\/bmj.f3591"},{"issue":"4","key":"2693_CR2","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1111\/j.1750-3639.2007.00100.x","volume":"17","author":"MF Casanova","year":"2007","unstructured":"Casanova MF (2007) The neuropathology of autism. Brain Pathol 17(4):422\u2013433. https:\/\/doi.org\/10.1111\/j.1750-3639.2007.00100.x","journal-title":"Brain Pathol"},{"key":"2693_CR3","doi-asserted-by":"crossref","unstructured":"Lefter R, Ciobica A, Timofte D, Stanciu C, Trifan A (2020) A descriptive review on the prevalence of gastrointestinal disturbances and their multiple associations in autism spectrum disorder. Medicina-Lithuania 56(1). ARTN 1110.3390\/medicina56010011","DOI":"10.3390\/medicina56010011"},{"key":"2693_CR4","doi-asserted-by":"publisher","first-page":"27","DOI":"10.3389\/fnint.2018.00027","volume":"12","author":"JB Barahona-Correa","year":"2018","unstructured":"Barahona-Correa JB, Velosa A, Chainho A, Lopes R, Oliveira-Maia AJ (2018) Repetitive transcranial magnetic stimulation for treatment of autism spectrum disorder: a systematic review and meta-analysis. Front Integr Neurosci 12:27. https:\/\/doi.org\/10.3389\/fnint.2018.00027","journal-title":"Front Integr Neurosci"},{"issue":"9","key":"2693_CR5","doi-asserted-by":"publisher","first-page":"2044","DOI":"10.1016\/j.neubiorev.2012.07.005","volume":"36","author":"S Coghlan","year":"2012","unstructured":"Coghlan S, Horder J, Inkster B, Mendez MA, Murphy DG, Nutt DJ (2012) GABA system dysfunction in autism and related disorders: from synapse to symptoms. Neurosci Biobehav Rev 36(9):2044\u20132055. https:\/\/doi.org\/10.1016\/j.neubiorev.2012.07.005","journal-title":"Neurosci Biobehav Rev"},{"issue":"1","key":"2693_CR6","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.mehy.2007.04.025","volume":"70","author":"MF Casanova","year":"2008","unstructured":"Casanova MF (2008) The minicolumnopathy of autism: a link between migraine and gastrointestinal symptoms. Med Hypotheses 70(1):73\u201380. https:\/\/doi.org\/10.1016\/j.mehy.2007.04.025","journal-title":"Med Hypotheses"},{"issue":"9","key":"2693_CR7","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1177\/088307380201700908","volume":"17","author":"MF Casanova","year":"2002","unstructured":"Casanova MF, Buxhoeveden DP, Brown C (2002) Clinical and macroscopic correlates of minicolumnar pathology in autism. J Child Neurol 17(9):692\u2013695","journal-title":"J Child Neurol"},{"key":"2693_CR8","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3389\/fnsys.2014.00134","volume":"8","author":"EM Sokhadze","year":"2014","unstructured":"Sokhadze EM, El-Baz AS, Sears LL, Opris I, Casanova MF (2014) rTMS neuromodulation improves electrocortical functional measures of information processing and behavioral responses in autism. Front Syst Neurosci 8:134. https:\/\/doi.org\/10.3389\/fnsys.2014.00134","journal-title":"Front Syst Neurosci"},{"key":"2693_CR9","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.psyneuen.2017.12.022","volume":"89","author":"O Oztan","year":"2018","unstructured":"Oztan O, Jackson LP, Libove RA, Sumiyoshi RD, Phillips JM, Garner JP et al (2018) Biomarker discovery for disease status and symptom severity in children with autism. Psychoneuroendocrinology 89:39\u201345. https:\/\/doi.org\/10.1016\/j.psyneuen.2017.12.022","journal-title":"Psychoneuroendocrinology"},{"key":"2693_CR10","first-page":"S179","volume":"74","author":"K McEvoy","year":"2013","unstructured":"McEvoy K, Jeste SS (2013) High frequency oscillations serve as a promising biomarker of autism spectrum disorders (ASD). Ann Neurol 74:S179\u2013S180","journal-title":"Ann Neurol"},{"key":"2693_CR11","doi-asserted-by":"crossref","unstructured":"Bosl W, Tierney A, Tager-Flusberg H, Nelson C (2011) EEG complexity as a biomarker for autism spectrum disorder risk. Bmc Medicine 9. Artn 1810.1186\/1741\u20137015\u20139\u201318","DOI":"10.1186\/1741-7015-9-18"},{"key":"2693_CR12","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.neucom.2018.04.080","volume":"324","author":"YZ Kong","year":"2019","unstructured":"Kong YZ, Gao JL, Xu YP, Pan Y, Wang JX, Liu J (2019) Classification of autism spectrum disorder by combining brain connectivity and deep neural network classifier. Neurocomputing 324:63\u201368. https:\/\/doi.org\/10.1016\/j.neucom.2018.04.080","journal-title":"Neurocomputing"},{"issue":"2","key":"2693_CR13","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/Wco.0000000000000301","volume":"29","author":"I Mohammad-Rezazadeh","year":"2016","unstructured":"Mohammad-Rezazadeh I, Frohlich J, Loo SK, Jeste SS (2016) Brain connectivity in autism spectrum disorder. Curr Opin Neurol 29(2):137\u2013147. https:\/\/doi.org\/10.1097\/Wco.0000000000000301","journal-title":"Curr Opin Neurol"},{"key":"2693_CR14","doi-asserted-by":"crossref","unstructured":"Shou GF, Mosconi MW, Wang J, Ethridge LE, Sweeney JA, Ding L (2017) Electrophysiological signatures of atypical intrinsic brain connectivity networks in autism. J Neural Eng 14(4). ARTN 04601010.1088\/1741\u20132552\/aa6b6b","DOI":"10.1088\/1741-2552\/aa6b6b"},{"key":"2693_CR15","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.neuroimage.2017.09.031","volume":"190","author":"MY Jung","year":"2019","unstructured":"Jung MY, Tu YH, Lang CA, Ortiz A, Park J, Jorgenson K et al (2019) Decreased structural connectivity and resting-state brain activity in the lateral occipital cortex is associated with social communication deficits in boys with autism spectrum disorder. Neuroimage 190:205\u2013212. https:\/\/doi.org\/10.1016\/j.neuroimage.2017.09.031","journal-title":"Neuroimage"},{"issue":"4","key":"2693_CR16","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.clinph.2016.10.002","volume":"128","author":"KJ Blinowska","year":"2017","unstructured":"Blinowska KJ, Rakowski F, Kaminski M, Fallani FD, Del Percio C, Lizio R et al (2017) Functional and effective brain connectivity for discrimination between Alzheimer\u2019s patients and healthy individuals: a study on resting state EEG rhythms. Clin Neurophysiol 128(4):667\u2013680. https:\/\/doi.org\/10.1016\/j.clinph.2016.10.002","journal-title":"Clin Neurophysiol"},{"issue":"2","key":"2693_CR17","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1002\/hbm.25683","volume":"43","author":"J Cao","year":"2022","unstructured":"Cao J, Zhao YF, Shan XC, Wei HL, Guo YZ, Chen LY et al (2022) Brain functional and effective connectivity based on electroencephalography recordings: a review. Hum Brain Mapp 43(2):860\u2013879. https:\/\/doi.org\/10.1002\/hbm.25683","journal-title":"Hum Brain Mapp"},{"issue":"12","key":"2693_CR18","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1016\/j.compbiomed.2011.06.020","volume":"41","author":"V Sakkalis","year":"2011","unstructured":"Sakkalis V (2011) Review of advanced techniques for the estimation of brain connectivity measured with EEG\/MEG. Comput Biol Med 41(12):1110\u20131117. https:\/\/doi.org\/10.1016\/j.compbiomed.2011.06.020","journal-title":"Comput Biol Med"},{"issue":"2","key":"2693_CR19","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/s004220000235","volume":"85","author":"M Kaminski","year":"2001","unstructured":"Kaminski M, Ding MZ, Truccolo WA, Bressler SL (2001) Evaluating causal relations in neural systems: Granger causality, directed transfer function and statistical assessment of significance. Biol Cybern 85(2):145\u2013157. https:\/\/doi.org\/10.1007\/s004220000235","journal-title":"Biol Cybern"},{"issue":"9","key":"2693_CR20","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1109\/Tbme.2004.827929","volume":"51","author":"R Kus","year":"2004","unstructured":"Kus R, Kaminski M, Blinowska KJ (2004) Determination of EEG activity propagation: pair-wise versus multichannel estimate. Ieee T Bio-Med Eng 51(9):1501\u20131510. https:\/\/doi.org\/10.1109\/Tbme.2004.827929","journal-title":"Ieee T Bio-Med Eng"},{"issue":"2","key":"2693_CR21","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.jneumeth.2013.02.021","volume":"215","author":"A Fasoula","year":"2013","unstructured":"Fasoula A, Attal Y, Schwartz D (2013) Comparative performance evaluation of data-driven causality measures applied to brain networks. J Neurosci Meth 215(2):170\u2013189. https:\/\/doi.org\/10.1016\/j.jneumeth.2013.02.021","journal-title":"J Neurosci Meth"},{"issue":"12","key":"2693_CR22","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.1109\/Tnsre.2020.3035836","volume":"28","author":"G Wang","year":"2020","unstructured":"Wang G, Wang D, Du CW, Li K, Zhang JH, Liu ZA et al (2020) Seizure prediction using directed transfer function and convolution neural network on intracranial EEG. Ieee T Neur Sys Reh 28(12):2711\u20132720. https:\/\/doi.org\/10.1109\/Tnsre.2020.3035836","journal-title":"Ieee T Neur Sys Reh"},{"issue":"1","key":"2693_CR23","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.apergo.2010.05.008","volume":"42","author":"JP Liu","year":"2010","unstructured":"Liu JP, Zhang C, Zheng CX (2010) Estimation of the cortical functional connectivity by directed transfer function during mental fatigue. Appl Ergon 42(1):114\u2013121. https:\/\/doi.org\/10.1016\/j.apergo.2010.05.008","journal-title":"Appl Ergon"},{"key":"2693_CR24","doi-asserted-by":"crossref","unstructured":"Olejarczyk E, Zuchowicz U, Wozniak-Kwasniewska A, Kaminski M, Szekely D, David O (2020) The impact of repetitive transcranial magnetic stimulation on functional connectivity in major depressive disorder and bipolar disorder evaluated by directed transfer function and indices based on graph theory. Int J Neural Syst 30(4). Artn 205001510.1142\/S012906572050015x.","DOI":"10.1142\/S012906572050015X"},{"issue":"1","key":"2693_CR25","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/Bf02211820","volume":"18","author":"FR Volkmar","year":"1988","unstructured":"Volkmar FR, Cicchetti DV, Dykens E, Sparrow SS, Leckman JF, Cohen DJ (1988) An evaluation of the Autism Behavior Checklist. J Autism Dev Disord 18(1):81\u201397. https:\/\/doi.org\/10.1007\/Bf02211820","journal-title":"J Autism Dev Disord"},{"issue":"12","key":"2693_CR26","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1177\/0306624x13511040","volume":"57","author":"RN Kocsis","year":"2013","unstructured":"Kocsis RN (2013) Diagnostic and statistical manual of mental disorders: fifth edition (DSM-5). Int J Offender Ther 57(12):1546\u20138. https:\/\/doi.org\/10.1177\/0306624x13511040","journal-title":"Int J Offender Ther"},{"key":"2693_CR27","doi-asserted-by":"crossref","unstructured":"Kang JN, Zhang ZM, Wan LY, Casanova MF, Sokhadze EM, Li XL (2022) Effects of 1Hz repetitive transcranial magnetic stimulation on autism with intellectual disability: a pilot study. Comput Biol Med 141. ARTN 10516710.1016\/j.compbiomed.2021.105167.","DOI":"10.1016\/j.compbiomed.2021.105167"},{"issue":"11","key":"2693_CR28","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1111\/cns.13150","volume":"25","author":"JN Kang","year":"2019","unstructured":"Kang JN, Song JJ, Casanova MF, Sokhadze EM, Li XL (2019) Effects of repetitive transcranial magnetic stimulation on children with low-function autism. CNS Neurosci Ther 25(11):1254\u20131261. https:\/\/doi.org\/10.1111\/cns.13150","journal-title":"CNS Neurosci Ther"},{"key":"2693_CR29","doi-asserted-by":"crossref","unstructured":"Sokhadze EM, Lamina EV, Casanova EL, Kelly DP, Opris I, Tasman A, et al. (2018) Exploratory study of rTMS neuromodulation effects on electrocortical functional measures of performance in an oddball test and behavioral symptoms in autism. Front Syst Neurosci 12. ARTN 2010.3389\/fnsys.2018.00020","DOI":"10.3389\/fnsys.2018.00020"},{"issue":"2","key":"2693_CR30","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.jneumeth.2010.11.015","volume":"195","author":"B He","year":"2011","unstructured":"He B, Dai Y, Astolfi L, Babiloni F, Yuan H, Yang L (2011) EConnectome: a MATLAB toolbox for mapping and imaging of brain functional connectivity. J Neurosci Methods 195(2):261\u2013269. https:\/\/doi.org\/10.1016\/j.jneumeth.2010.11.015","journal-title":"J Neurosci Methods"},{"key":"2693_CR31","doi-asserted-by":"publisher","unstructured":"Blinowska KJ (2011) Review of the methods of determination of directed connectivity from multichannel data. Med Biol Eng Comput 49:521\u2013529. https:\/\/doi.org\/10.1007\/s11517-011-0739-x","DOI":"10.1007\/s11517-011-0739-x"},{"issue":"3","key":"2693_CR32","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","volume":"52","author":"M Rubinov","year":"2010","unstructured":"Rubinov M, Sporns O (2010) Complex network measures of brain connectivity: uses and interpretations. Neuroimage 52(3):1059\u20131069. https:\/\/doi.org\/10.1016\/j.neuroimage.2009.10.003","journal-title":"Neuroimage"},{"key":"2693_CR33","doi-asserted-by":"crossref","unstructured":"Orekhova EV, Elsabbagh M, Jones EJH, Dawson G, Charman T, Johnson MH, et al. (2014) EEG hyper-connectivity in high-risk infants is associated with later autism. J Neurodev Disord 6. Artn 4010.1186\/1866\u20131955\u20136\u201340.","DOI":"10.1186\/1866-1955-6-40"},{"key":"2693_CR34","doi-asserted-by":"crossref","unstructured":"O'Reilly C, Lewis JD, Elsabbagh M. (2017) Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies. Plos One 12(5). ARTN e017587010.1371\/journal.pone.0175870.","DOI":"10.1371\/journal.pone.0175870"},{"issue":"1","key":"2693_CR35","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.neulet.2006.07.077","volume":"412","author":"N Schmitz","year":"2007","unstructured":"Schmitz N, Daly E, Murphy D (2007) Frontal anatomy and reaction time in Autism. Neurosci Lett 412(1):12\u201317. https:\/\/doi.org\/10.1016\/j.neulet.2006.07.077","journal-title":"Neurosci Lett"},{"issue":"5","key":"2693_CR36","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/j.1365-2990.2006.00745.x","volume":"32","author":"DP Buxhoeveden","year":"2006","unstructured":"Buxhoeveden DP, Semendeferi K, Buckwalter J, Schenker N, Switzer R, Courchesne E (2006) Reduced minicolumns in the frontal cortex of patients with autism. Neuropath Appl Neuro 32(5):483\u2013491. https:\/\/doi.org\/10.1111\/j.1365-2990.2006.00745.x","journal-title":"Neuropath Appl Neuro"},{"key":"2693_CR37","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.bbr.2013.05.055","volume":"251","author":"E Greimel","year":"2013","unstructured":"Greimel E, Bartling J, Dunkel J, Bruckl M, Deimel W, Remschmidt H et al (2013) The temporal dynamics of coherent motion processing in autism spectrum disorder: evidence for a deficit in the dorsal pathway. Behav Brain Res 251:168\u2013175. https:\/\/doi.org\/10.1016\/j.bbr.2013.05.055","journal-title":"Behav Brain Res"},{"issue":"5","key":"2693_CR38","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/j.mehy.2014.08.002","volume":"83","author":"RP Chi","year":"2014","unstructured":"Chi RP, Snyder AW (2014) Treating autism by targeting the temporal lobes. Med Hypotheses 83(5):614\u2013618. https:\/\/doi.org\/10.1016\/j.mehy.2014.08.002","journal-title":"Med Hypotheses"},{"issue":"2","key":"2693_CR39","doi-asserted-by":"publisher","first-page":"387","DOI":"10.2214\/ajr.160.2.8424359","volume":"160","author":"E Courchesne","year":"1993","unstructured":"Courchesne E, Press GA, Yeungcourchesne R (1993) Parietal lobe abnormalities detected with Mr in patients with infantile-autism. Am J Roentgenol 160(2):387\u2013393. https:\/\/doi.org\/10.2214\/ajr.160.2.8424359","journal-title":"Am J Roentgenol"},{"key":"2693_CR40","doi-asserted-by":"crossref","unstructured":"Awate SP, Win L, Yushkevich P, Schultz RT, Gee JC (2008) 3D Cerebral cortical morphometry in autism: increased folding in children and adolescents in frontal, parietal, and temporal lobes. Med Image Comput Comput-Assist Interv - Miccai 2008 Pt I Proc 5241:559-+","DOI":"10.1007\/978-3-540-85988-8_67"},{"issue":"8","key":"2693_CR41","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1002\/hbm.24074","volume":"39","author":"EPK Pua","year":"2018","unstructured":"Pua EPK, Malpas CB, Bowden SC, Seal ML (2018) Different brain networks underlying intelligence in autism spectrum disorders. Hum Brain Mapp 39(8):3253\u20133262. https:\/\/doi.org\/10.1002\/hbm.24074","journal-title":"Hum Brain Mapp"},{"key":"2693_CR42","doi-asserted-by":"publisher","first-page":"S226","DOI":"10.1016\/j.ijpsycho.2021.07.608","volume":"168","author":"S Zhang","year":"2021","unstructured":"Zhang S, Li FL, Jiang L, Peng YH, Yao DZ, Xu P (2021) Abnormal brain network connectivity in children with autism spectrum disorder. Int J Psychophysiol 168:S226-S. https:\/\/doi.org\/10.1016\/j.ijpsycho.2021.07.608","journal-title":"Int J Psychophysiol"}],"container-title":["Medical & Biological Engineering & Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-022-02693-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11517-022-02693-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-022-02693-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T17:16:28Z","timestamp":1668014188000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11517-022-02693-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,25]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2693"],"URL":"https:\/\/doi.org\/10.1007\/s11517-022-02693-y","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,25]]},"assertion":[{"value":"12 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}