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All experimental protocols involving humans were approved by the Ethical Review Approval of the Clinical Medical Research Ethics Committee of the First Affiliated Hospital of Anhui Medical University, No. PJ2021-08-42. Prior to the collection of any cellular material, comprehensive informed consent was obtained from all participants involved in this study. Participants were informed about the purposes of the research, the procedures to be undertaken, and the potential risks and benefits associated with their participation. Adequate measures were taken to ensure the confidentiality and privacy of the participants\u2019 data. Only de-identified data were used for analysis to further protect participant privacy and comply with ethical guidelines. The study adheres to the principles outlined in the Declaration of Helsinki regarding ethical conduct in human research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication was obtained from all individual participants involved in the study. All participants were informed that the information collected, including cellular data and associated analyses, might be published in scientific journals or presented at conferences. However, it was emphasized that all personal identifiers would be removed and all data would be presented in a way that ensures the utmost confidentiality and privacy.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}