{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:19:55Z","timestamp":1779916795232,"version":"3.53.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Spanish Government and co-financed by EU FEDER","award":["PID2020-117114GB-I00"],"award-info":[{"award-number":["PID2020-117114GB-I00"]}]},{"name":"Spanish Government and co-financed by EU FEDER","award":["CIPROM\/2023\/066"],"award-info":[{"award-number":["CIPROM\/2023\/066"]}]},{"name":"Spanish Government and co-financed by EU FEDER","award":["PID2021-125694OB-I00"],"award-info":[{"award-number":["PID2021-125694OB-I00"]}]},{"name":"Spanish Government and co-financed by EU FEDER","award":["CIAICO\/2021\/215"],"award-info":[{"award-number":["CIAICO\/2021\/215"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      We have analyzed the relationship between disability and neck flexion-extension kinematics in non-specific neck pain subjects. A functional approach is used considering the angle, velocity, and acceleration curves. Different regression models have been fitted for each time in order to obtain these curves using scalar predictors such as the Neck Disability Index (NDI), age, sex, and neck length. In addition to classical regression, a limma (Linear Models for Microarray Data) model has been used, which improves the fit by modifying the estimation of the variances of the different fits using an empirical Bayes approach. As point-by-point adjustments are performed, this introduces a multiple comparison problem, and the corresponding\n                      <jats:italic>p<\/jats:italic>\n                      -values have to be adjusted in order to control the false discovery rate (FDR). In particular, a Benjamini-Hochberg method was used. The results show significant differences between raw and adjusted\n                      <jats:italic>p<\/jats:italic>\n                      -values for all variables, so spurious results were detected, e.g., the effect of neck length on velocity and acceleration curves. Differences between usual multiple linear regressions and the modified fits using the limma method (limma models) are minor, with a slight decrement of\n                      <jats:italic>p<\/jats:italic>\n                      -values in limma models. Once the\n                      <jats:italic>p<\/jats:italic>\n                      -values are adjusted, none of the variables analyzed significantly affects the angular curves. In contrast, NDI and age affect velocity and acceleration curves. Furthermore, the study of\n                      <jats:italic>p<\/jats:italic>\n                      -values throughout the movement shows that velocity and acceleration curves provide complementary information, so they should be used together in neck kinematics studies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s11517-025-03400-3","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T04:52:20Z","timestamp":1751950340000},"page":"3435-3446","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Non-specific neck pain evaluation using functional linear models with the limma correction"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2890-9062","authenticated-orcid":false,"given":"Elisa","family":"Arag\u00f3n-Basanta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Ayala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Page","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Serra-A\u00f1\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"issue":"10267","key":"3400_CR1","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1016\/s0140-6736(20)32340-0","volume":"396","author":"A Cieza","year":"2020","unstructured":"Cieza A, Causey K, Kamenov K, Hanson SW, Chatterji S, Vos T (2020) Global estimates of the need for rehabilitation based on the global burden of disease study 2019: a systematic analysis for the global burden of disease study 2019. The Lancet. 396(10267):2006\u20132017. https:\/\/doi.org\/10.1016\/s0140-6736(20)32340-0","journal-title":"The Lancet."},{"key":"3400_CR2","doi-asserted-by":"publisher","unstructured":"Misailidou V, Malliou P, Beneka A, Karagiannidis A, Godolias G (2010) Assessment of patients with neck pain: a review of definitions, selection criteria, and measurement tools. 9(2):49\u201359 https:\/\/doi.org\/10.1016\/j.jcm.2010.03.002","DOI":"10.1016\/j.jcm.2010.03.002"},{"issue":"5","key":"3400_CR3","doi-asserted-by":"publisher","first-page":"0303365","DOI":"10.1371\/journal.pone.0303365","volume":"19","author":"S Soltanabadi","year":"2024","unstructured":"Soltanabadi S, Vatandoost S, Lukacs MJ, Rushton A, Walton DM (2024) Association between clinical biomechanical metrics of cervical spine function and pain or disability in people with neuromusculoskeletal neck pain: protocol for a systematic review and planned meta-analysis. PLoS ONE 19(5):0303365. https:\/\/doi.org\/10.1371\/journal.pone.0303365","journal-title":"PLoS ONE"},{"issue":"6","key":"3400_CR4","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1080\/10833196.2022.2143211","volume":"27","author":"A Luc","year":"2022","unstructured":"Luc A, Tamer S, Hage R, Detrembleur C, Pitance L (2022) Do the kinematics and sensorimotor control of people with chronic non-specific neck pain differ from those of healthy individuals when assessed in an immersive virtual reality environment? A systematic review. Phys Ther Rev 27(6):430\u2013443. https:\/\/doi.org\/10.1080\/10833196.2022.2143211","journal-title":"Phys Ther Rev"},{"issue":"4","key":"3400_CR5","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.physio.2019.01.007","volume":"105","author":"D Moghaddas","year":"2019","unstructured":"Moghaddas D, Zoete RMJ, Edwards S, Snodgrass SJ (2019) Differences in the kinematics of the cervical and thoracic spine during functional movement in individuals with or without chronic neck pain: a systematic review. Physiotherapy 105(4):421\u2013433. https:\/\/doi.org\/10.1016\/j.physio.2019.01.007","journal-title":"Physiotherapy"},{"issue":"7","key":"3400_CR6","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1016\/j.apmr.2016.10.003","volume":"98","author":"MS Stenneberg","year":"2017","unstructured":"Stenneberg MS, Rood M, Bie R, Schmitt MA, Cattrysse E, Scholten-Peeters GG (2017) To what degree does active cervical range of motion differ between patients with neck pain, patients with whiplash, and those without neck pain? A systematic review and meta-analysis. Arch Phys Med Rehabil 98(7):1407\u20131434. https:\/\/doi.org\/10.1016\/j.apmr.2016.10.003","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"3400_CR7","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.math.2014.10.002","volume":"20","author":"H Sarig Bahat","year":"2015","unstructured":"Sarig Bahat H, Chen X, Reznik D, Kodesh E, Treleaven J (2015) Interactive cervical motion kinematics: sensitivity, specificity and clinically significant values for identifying kinematic impairments in patients with chronic neck pain. Man Ther 20(2):295\u2013302. https:\/\/doi.org\/10.1016\/j.math.2014.10.002","journal-title":"Man Ther"},{"key":"3400_CR8","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.math.2015.10.015","volume":"22","author":"J Treleaven","year":"2016","unstructured":"Treleaven J, Chen X, Sarig Bahat H (2016) Factors associated with cervical kinematic impairments in patients with neck pain. Man Ther 22:109\u2013115. https:\/\/doi.org\/10.1016\/j.math.2015.10.015","journal-title":"Man Ther"},{"key":"3400_CR9","doi-asserted-by":"publisher","unstructured":"Franov E, Straub M, Bauer CM, Ernst MJ (2022) Head kinematics in patients with neck pain compared to asymptomatic controls: a systematic review. BMC Musculoskeletal Disorders. 23(1). https:\/\/doi.org\/10.1186\/s12891-022-05097-z","DOI":"10.1186\/s12891-022-05097-z"},{"key":"3400_CR10","doi-asserted-by":"publisher","unstructured":"Devecchi V, Alalawi A, Liew B, Falla D (2022) A network analysis reveals the interaction between fear and physical features in people with neck pain. Sci Rep 12(1). https:\/\/doi.org\/10.1038\/s41598-022-14696-8","DOI":"10.1038\/s41598-022-14696-8"},{"key":"3400_CR11","doi-asserted-by":"publisher","unstructured":"Ullah S, Finch CF (2013) Applications of functional data analysis: a systematic review. BMC Med Res Methodol 13(1). https:\/\/doi.org\/10.1186\/1471-2288-13-43","DOI":"10.1186\/1471-2288-13-43"},{"key":"3400_CR12","first-page":"211","volume":"55","author":"E Howell","year":"2011","unstructured":"Howell E (2011) The association between neck pain, the neck disability index and cervical ranges of motion: a narrative review. J Can Chiropr Assoc 55:211\u201321","journal-title":"J Can Chiropr Assoc"},{"key":"3400_CR13","doi-asserted-by":"publisher","unstructured":"Tsang SMH, Szeto GPY, So BCL, Lau RWL, Tai JJ (2022) Using cervical movement velocity to assist the prediction of pain and functional recovery for people with chronic mechanical neck pain. Clin Biomech 93:105607. https:\/\/doi.org\/10.1016\/j.clinbiomech.2022.105607","DOI":"10.1016\/j.clinbiomech.2022.105607"},{"issue":"5","key":"3400_CR14","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1007\/s11517-020-02153-5","volume":"58","author":"W Venegas","year":"2020","unstructured":"Venegas W, Ingl\u00e9s M, Page A, Serra-A\u00f1\u00f3 P (2020) Paths of the cervical instantaneous axis of rotation during active movements\u2013patterns and reliability. Med Biol Eng Comput 58(5):1147\u20131157. https:\/\/doi.org\/10.1007\/s11517-020-02153-5","journal-title":"Med Biol Eng Comput"},{"issue":"12","key":"3400_CR15","doi-asserted-by":"publisher","first-page":"2550","DOI":"10.1007\/s00586-012-2407-8","volume":"21","author":"W Jorritsma","year":"2012","unstructured":"Jorritsma W, Dijkstra PU, Vries GE, Geertzen JHB, Reneman MF (2012) Detecting relevant changes and responsiveness of neck pain and disability scale and neck disability index. Eur Spine J 21(12):2550\u20132557. https:\/\/doi.org\/10.1007\/s00586-012-2407-8","journal-title":"Eur Spine J"},{"key":"3400_CR16","doi-asserted-by":"publisher","unstructured":"Arag\u00f3n-Basanta E, Venegas W, Ayala G, Page A, o, P (2024) Relationship between neck kinematics and neck dissability index. An approach based on functional regression. Scientific Reports. 14(1). https:\/\/doi.org\/10.1038\/s41598-023-50562-x","DOI":"10.1038\/s41598-023-50562-x"},{"key":"3400_CR17","doi-asserted-by":"crossref","unstructured":"Ramsay J, Silverman BW (2005) Functional data analysis (Springer Series in Statistics). Springer, p 430","DOI":"10.1007\/b98888"},{"key":"3400_CR18","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.gaitpost.2020.02.002","volume":"77","author":"J Dannenmaier","year":"2020","unstructured":"Dannenmaier J, Kaltenbach C, K\u00f6lle T, Krischak G (2020) Application of functional data analysis to explore movements: walking, running and jumping - a systematic review. Gait & Posture. 77:182\u2013189. https:\/\/doi.org\/10.1016\/j.gaitpost.2020.02.002","journal-title":"Gait & Posture."},{"issue":"10","key":"3400_CR19","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1016\/j.jsams.2018.03.009","volume":"21","author":"J Warmenhoven","year":"2018","unstructured":"Warmenhoven J, Harrison A, Robinson MA, Vanrenterghem J, Bargary N, Smith R, Cobley S, Draper C, Donnelly C, Pataky T (2018) A force profile analysis comparison between functional data analysis, statistical parametric mapping and statistical non-parametric mapping in on-water single sculling. J Sci Med Sport 21(10):1100\u20131105. https:\/\/doi.org\/10.1016\/j.jsams.2018.03.009","journal-title":"J Sci Med Sport"},{"key":"3400_CR20","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.gaitpost.2019.12.008","volume":"76","author":"BXW Liew","year":"2020","unstructured":"Liew BXW, Rugamer D, Stocker A, De Nunzio AM (2020) Classifying neck pain status using scalar and functional biomechanical variables \u2013 development of a method using functional data boosting. Gait & Posture. 76:146\u2013150. https:\/\/doi.org\/10.1016\/j.gaitpost.2019.12.008","journal-title":"Gait & Posture."},{"key":"3400_CR21","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.gaitpost.2023.01.012","volume":"100","author":"DR Dewig","year":"2023","unstructured":"Dewig DR, Evans-Pickett A, Pietrosimone BG, Blackburn JT (2023) Comparison of discrete and continuous analysis approaches for evaluating gait biomechanics in individuals with anterior cruciate ligament reconstruction. Gait & Posture. 100:261\u2013267. https:\/\/doi.org\/10.1016\/j.gaitpost.2023.01.012","journal-title":"Gait & Posture."},{"key":"3400_CR22","doi-asserted-by":"publisher","unstructured":"Mazlan MH, Osman NAA, Abas WABW (2011) Hip 3D joint mechanics analysis of normal and obese individuals\u2019 gait. Springer, pp 161\u2013166. https:\/\/doi.org\/10.1007\/978-3-642-21729-6_43","DOI":"10.1007\/978-3-642-21729-6_43"},{"issue":"9","key":"3400_CR23","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1016\/j.jbiomech.2016.03.032","volume":"49","author":"TC Pataky","year":"2016","unstructured":"Pataky TC, Vanrenterghem J, Robinson MA (2016) The probability of false positives in zero-dimensional analyses of one-dimensional kinematic, force and emg trajectories. J Biomech 49(9):1468\u20131476. https:\/\/doi.org\/10.1016\/j.jbiomech.2016.03.032","journal-title":"J Biomech"},{"issue":"3","key":"3400_CR24","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1007\/s11749-020-00751-x","volume":"30","author":"NL Olsen","year":"2021","unstructured":"Olsen NL, Pini A, Vantini S (2021) False discovery rate for functional data. TEST 30(3):784\u2013809. https:\/\/doi.org\/10.1007\/s11749-020-00751-x","journal-title":"TEST"},{"issue":"7","key":"3400_CR25","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.jmpt.2008.08.006","volume":"31","author":"H Vernon","year":"2008","unstructured":"Vernon H (2008) The neck disability index: state-of-the-art, 1991\u20132008. J Manipulative Physiol Ther 31(7):491\u2013502. https:\/\/doi.org\/10.1016\/j.jmpt.2008.08.006","journal-title":"J Manipulative Physiol Ther"},{"key":"3400_CR26","doi-asserted-by":"crossref","unstructured":"Smyth GK (2004) Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 1:3","DOI":"10.2202\/1544-6115.1027"},{"issue":"7","key":"3400_CR27","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):47. https:\/\/doi.org\/10.1093\/nar\/gkv007","journal-title":"Nucleic Acids Res"},{"key":"3400_CR28","doi-asserted-by":"crossref","unstructured":"Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society. Series B (Methodological). 57(1):289\u2013300","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"issue":"1","key":"3400_CR29","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.jmpt.2023.05.006","volume":"46","author":"P Serra-A\u00f1\u00f3","year":"2023","unstructured":"Serra-A\u00f1\u00f3 P, Venegas W, Page A, Torre M, Aguilar-Rodr\u00edguez M, Esp\u00ed-L\u00f3pez G (2023) Immediate effects of a single session of cervical spine manipulation on cervical movement patterns in people with nonspecific neck pain: a randomized controlled trial. J Manipulative Physiol Ther 46(1):17\u201326. https:\/\/doi.org\/10.1016\/j.jmpt.2023.05.006","journal-title":"J Manipulative Physiol Ther"},{"key":"3400_CR30","doi-asserted-by":"publisher","unstructured":"Page A, Rosario H, Mata V, Atienza C (2009) Experimental analysis of rigid body motion. A vector method to determine finite and infinitesimal displacements from point coordinates. J Mech Des 131(3). https:\/\/doi.org\/10.1115\/1.3066468","DOI":"10.1115\/1.3066468"},{"issue":"4","key":"3400_CR31","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1097\/brs.0b013e3181afea5d","volume":"35","author":"JA Andrade Ortega","year":"2010","unstructured":"Andrade Ortega JA, Delgado Mart\u00ednez AD, Ruiz RA (2010) Validation of the Spanish version of the neck disability index. Spine 35(4):114\u2013118. https:\/\/doi.org\/10.1097\/brs.0b013e3181afea5d","journal-title":"Spine"},{"key":"3400_CR32","doi-asserted-by":"publisher","unstructured":"Page A, Ingl\u00e9s M, Venegas W, Moll\u00e0-Casanova S, Serra-A\u00f1\u00f3 P (2023) Effect of non-specific neck pain on the path of the instantaneous axis of rotation of the neck during its flexion-extension movement. Musculoskelet Sci Pract 64:102737. https:\/\/doi.org\/10.1016\/j.msksp.2023.102737","DOI":"10.1016\/j.msksp.2023.102737"},{"issue":"4","key":"3400_CR33","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1214\/aos\/1013699998","volume":"29","author":"Y Benjamini","year":"2001","unstructured":"Benjamini Y, Yekutieli D (2001) The control of the false discovery rate in multiple testing under dependency. Ann Stat 29(4):1165\u20131188","journal-title":"Ann Stat"},{"key":"3400_CR34","unstructured":"R Core Team: R (2025) A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. R Found Stat Comput. https:\/\/www.R-project.org\/"},{"key":"3400_CR35","unstructured":"Ramsay J (2023) FDA: functional data analysis. R package version 6.1.4. https:\/\/CRAN.R-project.org\/package=fda"},{"key":"3400_CR36","doi-asserted-by":"crossref","unstructured":"Febrero-Bande M, Oviedo de la Fuente M (2012) Statistical computing in functional data analysis: the R package fda.usc. J Stat Softw 51(4):1\u201328","DOI":"10.18637\/jss.v051.i04"},{"issue":"7","key":"3400_CR37","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"ME Ritchie","year":"2015","unstructured":"Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, Smyth GK (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):47. https:\/\/doi.org\/10.1093\/nar\/gkv007","journal-title":"Nucleic Acids Res"},{"key":"3400_CR38","doi-asserted-by":"crossref","unstructured":"Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Ole\u2019s AK, Pag\u2018es H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015) Orchestrating high-throughput genomic analysis with Bioconductor. Nat Methods 12(2):115\u2013121","DOI":"10.1038\/nmeth.3252"},{"key":"3400_CR39","doi-asserted-by":"crossref","unstructured":"Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Ole\u2019s AK, Pag\u2018es H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015) Orchestrating high-throughput genomic analysis with Bioconductor. Nat Methods 12(2):115\u2013121","DOI":"10.1038\/nmeth.3252"},{"issue":"1","key":"3400_CR40","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.clinbiomech.2010.08.008","volume":"26","author":"JM Baydal-Bertomeu","year":"2011","unstructured":"Baydal-Bertomeu JM, Page AF, Belda-Lois JM, Garrido-Ja\u00e9n D, Prat JM (2011) Neck motion patterns in whiplash-associated disorders: quantifying variability and spontaneity of movement. Clin Biomech 26(1):29\u201334. https:\/\/doi.org\/10.1016\/j.clinbiomech.2010.08.008","journal-title":"Clin Biomech"},{"issue":"9","key":"3400_CR41","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1002\/lary.29488","volume":"131","author":"LC Maga\u00f1a","year":"2021","unstructured":"Maga\u00f1a LC, Murati S, Riffitts M, Harrison C, Harris A, Sowa G, Johnson JT, Bell K, Nilsen M (2021) Subjective and objective measures in assessing neck disability and pain in head and neck cancer. Laryngoscope 131(9):2015\u20132022. https:\/\/doi.org\/10.1002\/lary.29488","journal-title":"Laryngoscope"},{"issue":"17","key":"3400_CR42","doi-asserted-by":"publisher","first-page":"3805","DOI":"10.3390\/jcm10173805","volume":"10","author":"CF Pinheiro","year":"2021","unstructured":"Pinheiro CF, Oliveira AS, Will-Lemos T, Florencio LL, Fern\u00e1ndez-de-las-Pe\u00f1as C, Dach F, Bevilaqua-Grossi D (2021) Neck active movements assessment in women with episodic and chronic migraine. J Clin Med 10(17):3805. https:\/\/doi.org\/10.3390\/jcm10173805","journal-title":"J Clin Med"},{"key":"3400_CR43","doi-asserted-by":"publisher","unstructured":"Bahat HS, Igbariya M, Quek J, Treleaven J (2016) Cervical kinematics of fast neck motion across age. J Novel Physiotherapies 6(5). https:\/\/doi.org\/10.4172\/2165-7025.1000306","DOI":"10.4172\/2165-7025.1000306"},{"key":"3400_CR44","doi-asserted-by":"publisher","first-page":"261","DOI":"10.2147\/mder.s475166","volume":"17","author":"W Liengswangwong","year":"2024","unstructured":"Liengswangwong W, Lertviboonluk N, Yuksen C, Jamkrajang P, Limroongreungrat W, Mongkolpichayaruk A, Jenpanitpong C, Watcharakitpaisan S, Palee C, Reechaipichitkool P, Thaipasong S (2024) Validity of inertial measurement unit (IMU sensor) for measurement of cervical spine motion, compared with eight optoelectronic 3d cameras under spinal immobilization devices. Med Devices: Evid Res 17:261\u2013269. https:\/\/doi.org\/10.2147\/mder.s475166","journal-title":"Med Devices: Evid Res"},{"issue":"6","key":"3400_CR45","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.3390\/s23063077","volume":"23","author":"M Trinidad-Fern\u00e1ndez","year":"2023","unstructured":"Trinidad-Fern\u00e1ndez M, Bossavit B, Salgado-Fern\u00e1ndez J, Abbate-Chica S, Fern\u00e1ndez-Leiva AJ, Cuesta-Vargas AI (2023) Head-mounted display for clinical evaluation of neck movement validation with meta quest 2. Sensors 23(6):3077. https:\/\/doi.org\/10.3390\/s23063077","journal-title":"Sensors"}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03400-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11517-025-03400-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03400-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T07:32:57Z","timestamp":1763623977000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11517-025-03400-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,8]]},"references-count":45,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["3400"],"URL":"https:\/\/doi.org\/10.1007\/s11517-025-03400-3","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,8]]},"assertion":[{"value":"24 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}