{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T07:10:25Z","timestamp":1772262625994,"version":"3.50.1"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62201141"],"award-info":[{"award-number":["62201141"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s11517-025-03458-z","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T04:48:37Z","timestamp":1762750117000},"page":"619-632","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["DPCM-DP-EN: a lossless dynamic compress and encrypted encode method for DNA storage of medical images with high storage density"],"prefix":"10.1007","volume":"64","author":[{"given":"Kun","family":"Bi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zilin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yitong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingjiang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuhong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"3458_CR1","doi-asserted-by":"publisher","unstructured":"Behnam F, Khajouei R, Ahmadian L (2024) The retention duration of digitalimages in picture archiving and communication systems. Heliyon 10. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e27847","DOI":"10.1016\/j.heliyon.2024.e27847"},{"key":"3458_CR2","doi-asserted-by":"crossref","unstructured":"Wang Y, Kung L, Ting C, Byrd TA (2015) Beyond a technical perspective: understanding big data capabilities in health care. In: 2015 48th Hawaii International Conference on System Sciences: 2015: IEEE, pp 3044\u20133053","DOI":"10.1109\/HICSS.2015.368"},{"issue":"5","key":"3458_CR3","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/j.jbi.2013.07.001","volume":"46","author":"A O\u2019Driscoll","year":"2013","unstructured":"O\u2019Driscoll A, Daugelaite J, Sleator RD (2013) \u2018Big data\u2019, Hadoop and cloud computing in genomics. J Biomed Inform 46(5):774\u2013781","journal-title":"J Biomed Inform"},{"key":"3458_CR4","first-page":"175","volume":"2","author":"L Hong","year":"2018","unstructured":"Hong L, Luo M, Wang R, Lu P, Lu W, Lu L (2018) Big data in health care: applications and challenges. Data Inf Manag 2:175\u2013197","journal-title":"Data Inf Manag"},{"issue":"5","key":"3458_CR5","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1109\/JPROC.2021.3054390","volume":"109","author":"SK Zhou","year":"2021","unstructured":"Zhou SK, Greenspan H, Davatzikos C, Duncan JS, Van Ginneken B, Madabhushi A, Prince JL, Rueckert D, Summers RM (2021) A review of deep learning in medical imaging: imaging traits, technology trends, case studies with progress highlights, and future promises. Proc IEEE 109(5):820\u2013838","journal-title":"Proc IEEE"},{"key":"3458_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.image.2021.116331","volume":"97","author":"M Dimopoulou","year":"2021","unstructured":"Dimopoulou M, Antonini M, Barbry P, Appuswamy R (2021) Image storage onto synthetic DNA. Signal Process Image Commun 97:116331","journal-title":"Signal Process Image Commun"},{"issue":"4","key":"3458_CR7","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1007\/s11277-022-09931-4","volume":"131","author":"M Ebied","year":"2023","unstructured":"Ebied M, Elmisery FA, El-Hag NA, Sedik A, El-Shafai W, El-Banby GM, Soltan E, Al-Zubi N, Brisha A, Zekry A (2023) A proposed deep-learning-based framework for medical image communication, storage and diagnosis. Wirel Pers Commun 131(4):2331\u20132369","journal-title":"Wirel Pers Commun"},{"issue":"2","key":"3458_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/technologies12020017","volume":"12","author":"AK Shakya","year":"2024","unstructured":"Shakya AK, Vidyarthi A (2024) Comprehensive study of compression and texture integration for digital imaging and communications in medicine data analysis. Technologies 12(2):17","journal-title":"Technologies"},{"issue":"2","key":"3458_CR9","doi-asserted-by":"publisher","first-page":"2000046","DOI":"10.1002\/sstr.202000046","volume":"2","author":"Y Hao","year":"2021","unstructured":"Hao Y, Li Q, Fan C, Wang F (2021) Data storage based on DNA. Small Struct 2(2):2000046","journal-title":"Small Struct"},{"key":"3458_CR10","doi-asserted-by":"crossref","unstructured":"Baek D, Joe SY, Shin H, Park C, Jo S, Chun H (2024) Recent progress in high-throughput enzymatic DNA synthesis for data storage. BioChip J 18(3):357-372","DOI":"10.1007\/s13206-024-00146-2"},{"issue":"3","key":"3458_CR11","doi-asserted-by":"publisher","first-page":"bbae125","DOI":"10.1093\/bib\/bbae125","volume":"25","author":"Y Li","year":"2024","unstructured":"Li Y, Zhang H, Chen Y, Shen Y, Ping Z (2024) DNA bloom filter enables anti-contamination and file version control for DNA-based data storage. Brief Bioinform 25(3):bbae125","journal-title":"Brief Bioinform"},{"issue":"1","key":"3458_CR12","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s13640-022-00600-x","volume":"2022","author":"M Dimopoulou","year":"2022","unstructured":"Dimopoulou M, Antonini M (2022) Data and image storage on synthetic DNA: existing solutions and challenges. EURASIP J Image Video Process 2022(1):23","journal-title":"EURASIP J Image Video Process"},{"key":"3458_CR13","doi-asserted-by":"publisher","DOI":"10.1039\/D3CS00469D","author":"M Yu","year":"2024","unstructured":"Yu M, Tang X, Li Z, Wang W, Wang S, Li M, Yu Q, Xie S, Zuo X, Chen C (2024) High-throughput DNA synthesis for data storage. Chem Soc Rev. https:\/\/doi.org\/10.1039\/D3CS00469D","journal-title":"Chem Soc Rev"},{"issue":"12","key":"3458_CR14","doi-asserted-by":"publisher","first-page":"3623","DOI":"10.1007\/s11517-024-03156-2","volume":"62","author":"K Bi","year":"2024","unstructured":"Bi K, Xu Q, Lai X, Zhao X, Lu Z (2024) Multi-file dynamic compression method based on classification algorithm in DNA storage. Med Biol Eng Comput 62(12):3623. https:\/\/doi.org\/10.1007\/s11517-024-03156-2","journal-title":"Med Biol Eng Comput"},{"issue":"6102","key":"3458_CR15","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1126\/science.1226355","volume":"337","author":"GM Church","year":"2012","unstructured":"Church GM, Gao Y, Kosuri S (2012) Next-generation digital information storage in DNA. Science 337(6102):1628\u20131628","journal-title":"Science"},{"issue":"6328","key":"3458_CR16","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1126\/science.aaj2038","volume":"355","author":"Y Erlich","year":"2017","unstructured":"Erlich Y, Zielinski D (2017) DNA fountain enables a robust and efficient storage architecture. Science 355(6328):950\u2013954","journal-title":"Science"},{"key":"3458_CR17","doi-asserted-by":"crossref","unstructured":"Zhang J, Chen S, Zhang H, Shen Y, Ping Z (2021) DNA image storage using a scheme based on fuzzy matching on natural genome. In: International Symposium on Bioinformatics Research and Applications: 2021: Springer, pp 572\u2013583","DOI":"10.1007\/978-3-030-91415-8_48"},{"issue":"4","key":"3458_CR18","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1038\/s43588-022-00231-2","volume":"2","author":"Z Ping","year":"2022","unstructured":"Ping Z, Chen S, Zhou G, Huang X, Zhu SJ, Zhang H, Lee HH, Lan Z, Cui J, Chen T (2022) Towards practical and robust DNA-based data archiving using the yin\u2013yang codec system. Nat Comput Sci 2(4):234\u2013242","journal-title":"Nat Comput Sci"},{"key":"3458_CR19","doi-asserted-by":"publisher","unstructured":"Rasool A, Hong J, Hong Z, Li Y, Zou C, Chen H, Qu Q, Wang Y, Jiang Q, Huang X (2024) An effective DNA\u2010based file storage system for practical archiving and retrieval of medical MRI data. Small Methods. https:\/\/doi.org\/10.1002\/smtd.202301585","DOI":"10.1002\/smtd.202301585"},{"key":"3458_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.sigpro.2022.108621","volume":"199","author":"M Dzwonkowski","year":"2022","unstructured":"Dzwonkowski M, Czaplewski B (2022) Reversible data hiding in encrypted DICOM images using sorted binary sequences of pixels. Signal Process 199:108621","journal-title":"Signal Process"},{"issue":"3","key":"3458_CR21","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/s12539-023-00565-z","volume":"15","author":"X Yao","year":"2023","unstructured":"Yao X, Xie R, Zan X, Su Y, Xu P, Liu W (2023) A novel image encryption scheme for DNA storage systems based on DNA hybridization and gene mutation. Interdisc Sci Comput Life Sci 15(3):419\u2013432","journal-title":"Interdisc Sci Comput Life Sci"},{"issue":"5","key":"3458_CR22","doi-asserted-by":"publisher","first-page":"401","DOI":"10.2174\/1574893617666220314114732","volume":"17","author":"K Bi","year":"2022","unstructured":"Bi K, Lu Z, Ge Q, Gu W (2022) Extended XOR algorithm with biotechnology constraints for data security in DNA storage. Curr Bioinf 17(5):401\u2013410","journal-title":"Curr Bioinf"},{"key":"3458_CR23","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.sigpro.2016.12.008","volume":"134","author":"T Hu","year":"2017","unstructured":"Hu T, Liu Y, Gong L-H, Guo S-F, Yuan H-M (2017) Chaotic image cryptosystem using DNA deletion and DNA insertion. Signal Process 134:234\u2013243","journal-title":"Signal Process"},{"key":"3458_CR24","doi-asserted-by":"publisher","first-page":"104791","DOI":"10.1016\/j.bspc.2023.104791","volume":"84","author":"H Xiao","year":"2023","unstructured":"Xiao H, Li L, Liu Q, Zhu X, Zhang Q (2023) Transformers in medical image segmentation: a review. Biomed Signal Process Control 84:104791","journal-title":"Biomed Signal Process Control"},{"key":"3458_CR25","doi-asserted-by":"publisher","unstructured":"Wu J, Kamath M, Noseworthy MD, Boylan C, Poehlman S (2008) Segmentation of images of abdominal organs. Crit Rev Biomed Eng.https:\/\/doi.org\/10.1615\/CritRevBiomedEng.v36.i5-6.10","DOI":"10.1615\/CritRevBiomedEng.v36.i5-6.10"},{"key":"3458_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2019.104863","volume":"28","author":"W Al-Dhabyani","year":"2020","unstructured":"Al-Dhabyani W, Gomaa M, Khaled H, Fahmy A (2020) Dataset of breast ultrasound images. Data Brief 28:104863","journal-title":"Data Brief"},{"issue":"6","key":"3458_CR27","first-page":"1813","volume":"20","author":"I Hwang","year":"2021","unstructured":"Hwang I, Yun J, Chung W, Lee J, Kim C-G, Kim Y, Park W-C (2021) Lossless compression algorithm and architecture for reduced memory bandwidth requirement with improved prediction based on the multiple DPCM Golomb-Rice algorithm. J Web Eng 20(6):1813\u20131828","journal-title":"J Web Eng"},{"key":"3458_CR28","doi-asserted-by":"crossref","unstructured":"Tomar RRS, Jain K (2015) Lossless image compression using differential pulse code modulation and its application. In: 2015 International Conference on Computational Intelligence and Communication Networks (CICN): 2015: IEEE, pp 397\u2013400","DOI":"10.1109\/CICN.2015.84"},{"issue":"4","key":"3458_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1145\/3626233","volume":"56","author":"T Heinis","year":"2023","unstructured":"Heinis T, Sokolovskii R, Alnasir JJ (2023) Survey of information encoding techniques for DNA. ACM Comput Surv 56(4):1\u201330","journal-title":"ACM Comput Surv"},{"key":"3458_CR30","doi-asserted-by":"publisher","unstructured":"Dimopoulou M, San Antonio EG, Antonini M (2021) A JPEG-based image coding solution for data storage on DNA. In: 2021 29th European Signal Processing Conference (EUSIPCO) IEEE. https:\/\/doi.org\/10.23919\/EUSIPCO54536.2021.9616020","DOI":"10.23919\/EUSIPCO54536.2021.9616020"},{"issue":"3","key":"3458_CR31","doi-asserted-by":"publisher","first-page":"btae113","DOI":"10.1093\/bioinformatics\/btae113","volume":"40","author":"X Zhang","year":"2024","unstructured":"Zhang X, Qi B, Niu Y (2024) A dual-rule encoding DNA storage system using chaotic mapping to control GC content. Bioinformatics 40(3):btae113","journal-title":"Bioinformatics"},{"issue":"1","key":"3458_CR32","doi-asserted-by":"publisher","first-page":"9663","DOI":"10.1038\/s41598-019-45832-6","volume":"9","author":"R Heckel","year":"2019","unstructured":"Heckel R, Mikutis G, Grass RN (2019) A characterization of the DNA data storage channel. Sci Rep 9(1):9663","journal-title":"Sci Rep"},{"key":"3458_CR33","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1109\/TNB.2021.3102122","volume":"20","author":"J Wu","year":"2021","unstructured":"Wu J, Zhang S, Zhang T, Liu Y (2021) HD-code: end-to-end high density code for DNA storage. IEEE Trans Nanobiosci 20:455\u2013463","journal-title":"IEEE Trans Nanobiosci"},{"issue":"8","key":"3458_CR34","doi-asserted-by":"publisher","first-page":"2552","DOI":"10.1002\/anie.201411378","volume":"54","author":"RN Grass","year":"2015","unstructured":"Grass RN, Heckel R, Puddu M, Paunescu D, Stark WJ (2015) Robust chemical preservation of digital information on DNA in silica with error-correcting codes. Angew Chem Int Ed 54(8):2552\u20132555","journal-title":"Angew Chem Int Ed"},{"issue":"3","key":"3458_CR35","first-page":"412","volume":"2","author":"Z Ping","year":"2021","unstructured":"Ping Z, Zhang H, Shihong C, Ni M, Xu X, Zhu S, Shen Y (2021) Chamaeleo: an integrated evaluation platform for DNA storage. Synth Biol J 2(3):412\u2013427","journal-title":"Synth Biol J"},{"key":"3458_CR36","doi-asserted-by":"publisher","unstructured":"Rahman, Md M (2024) Braincancer - MRI dataset. Mendeley Data, V1. https:\/\/doi.org\/10.17632\/mk56jw9rns.1","DOI":"10.17632\/mk56jw9rns.1"},{"key":"3458_CR37","doi-asserted-by":"publisher","unstructured":"Kermany D, Zhang K, Goldbaum M (2018) Labeled optical coherencetomography (OCT) and chest X-ray images for classification. Mendeley Data, V2. https:\/\/doi.org\/10.17632\/rscbjbr9sj.2","DOI":"10.17632\/rscbjbr9sj.2"},{"key":"3458_CR38","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.sigpro.2017.07.034","volume":"142","author":"J Chen","year":"2018","unstructured":"Chen J, Zhu Z-l, Zhang L-b, Zhang Y, Yang B-q (2018) Exploiting self-adaptive permutation\u2013diffusion and DNA random encoding for secure and efficient image encryption. Signal Process 142:340\u2013353","journal-title":"Signal Process"},{"issue":"8","key":"3458_CR39","doi-asserted-by":"publisher","DOI":"10.3390\/math12081235","volume":"12","author":"J Hong","year":"2024","unstructured":"Hong J, Rasool A, Wang S, Ziou D, Jiang Q (2024) VSD: a novel method for video segmentation and storage in DNA using RS code. Mathematics 12(8):1235","journal-title":"Mathematics"}],"container-title":["Medical & Biological Engineering & Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03458-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11517-025-03458-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03458-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:26:11Z","timestamp":1772252771000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11517-025-03458-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["3458"],"URL":"https:\/\/doi.org\/10.1007\/s11517-025-03458-z","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"27 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study is based on open-source dataset and license can be found in Kaggle website, so there are no ethical issues.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}