{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T07:40:55Z","timestamp":1781595655931,"version":"3.54.5"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00347319"],"award-info":[{"award-number":["RS-2024-00347319"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1007\/s11517-025-03486-9","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T05:12:00Z","timestamp":1763183520000},"page":"669-683","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Computational analysis of haemodynamics and oxygen distribution in the patient-specific aorta during VA-ECMO under various clinical scenarios"],"prefix":"10.1007","volume":"64","author":[{"given":"Jin-Gyeong","family":"Im","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Yun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Seok","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1300-0467","authenticated-orcid":false,"given":"Boram","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,15]]},"reference":[{"key":"3486_CR1","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.tmrv.2014.12.001","volume":"29","author":"DA Murphy","year":"2015","unstructured":"Murphy DA, Hockings LE, Andrews RK, Aubron C, Gardiner EE, Pellegrino VA et al (2015) Extracorporeal membrane oxygenation-hemostatic complications. Transfus Med Rev 29:90\u2013101. https:\/\/doi.org\/10.1016\/j.tmrv.2014.12.001","journal-title":"Transfus Med Rev"},{"key":"3486_CR2","doi-asserted-by":"publisher","first-page":"E166","DOI":"10.3978\/j.issn.2072-1439.2015.07.17","volume":"7","author":"G Makdisi","year":"2015","unstructured":"Makdisi G, Wang IW (2015) Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology. J Thorac Dis 7:E166\u2013E176. https:\/\/doi.org\/10.3978\/j.issn.2072-1439.2015.07.17","journal-title":"J Thorac Dis"},{"key":"3486_CR3","doi-asserted-by":"publisher","first-page":"410","DOI":"10.5935\/0103-507X.20190063","volume":"31","author":"RC Chaves","year":"2019","unstructured":"Chaves RC, de F, Rabello Filho R, Timenetsky KT, Moreira FT, Vilanova LC, da Bravim S (2019) Oxigena\u00e7\u00e3o Por membrana extracorp\u00f3rea: revis\u00e3o Da literatura. Rev Bras Ter Intensiva 31:410\u2013424. https:\/\/doi.org\/10.5935\/0103-507X.20190063","journal-title":"Rev Bras Ter Intensiva"},{"key":"3486_CR4","first-page":"80","volume":"22","author":"RH Bartlett","year":"1976","unstructured":"Bartlett RH, Gazzaniga AB, Jefferies MR, Huxtable RF, Haiduc NJ, Fong SW (1976) Extracorporeal membrane oxygenation (ECMO) cardiopulmonary support in infancy. Trans Am Soc Artif Intern Organs 22:80\u201393","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"3486_CR5","first-page":"534","volume":"76","author":"RH Bartlett","year":"2010","unstructured":"Bartlett RH, Gattinoni L (2010) Current status of extracorporeal life support (ECMO) for cardiopulmonary failure. Minerva Anestesiol 76:534\u2013540","journal-title":"Minerva Anestesiol"},{"key":"3486_CR6","first-page":"172","volume":"15","author":"A Zangrillo","year":"2013","unstructured":"Zangrillo A, Landoni G, Biondi-Zoccai G, Greco M, Greco T, Frati G et al (2013) A meta-analysis of complications and mortality of extracorporeal membrane oxygenation. Crit Care Resusc 15:172\u2013178","journal-title":"Crit Care Resusc"},{"key":"3486_CR7","doi-asserted-by":"publisher","first-page":"6993","DOI":"10.21037\/jtd.2018.11.103","volume":"10","author":"V Lo Coco","year":"2018","unstructured":"Lo Coco V, Lorusso R, Raffa GM, Malvindi PG, Pilato M, Martucci G et al (2018) Clinical complications during veno-arterial extracorporeal membrane oxigenation in post-cardiotomy and non post-cardiotomy shock: still the achille\u2019s heel. J Thorac Dis 10:6993\u20137004. https:\/\/doi.org\/10.21037\/jtd.2018.11.103","journal-title":"J Thorac Dis"},{"key":"3486_CR8","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1097\/MAT.0000000000000475","volume":"63","author":"RR Thiagarajan","year":"2017","unstructured":"Thiagarajan RR, Barbaro RP, Rycus PT, McMullan DM, Conrad SA, Fortenberry JD et al (2017) Extracorporeal life support organization registry international report 2016. ASAIO J 63:60\u201367. https:\/\/doi.org\/10.1097\/MAT.0000000000000475","journal-title":"ASAIO J"},{"key":"3486_CR9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.118.004905","volume":"11","author":"P Rao","year":"2018","unstructured":"Rao P, Khalpey Z, Smith R, Burkhoff D, Kociol RD (2018) Venoarterial extracorporeal membrane oxygenation for cardiogenic shock and cardiac arrest. Circ Heart Fail 11:e004905. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.118.004905","journal-title":"Circ Heart Fail"},{"key":"3486_CR10","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1053\/j.jvca.2018.05.028","volume":"33","author":"A Alexis-Ruiz","year":"2019","unstructured":"Alexis-Ruiz A, Ghadimi K, Raiten J, Mackay E, Laudanski K, Cannon J et al (2019) Hypoxia and complications of oxygenation in extracorporeal membrane oxygenation. J Cardiothorac Vasc Anesth 33:1375\u20131381. https:\/\/doi.org\/10.1053\/j.jvca.2018.05.028","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"3486_CR11","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.ijcard.2015.03.311","volume":"187","author":"LC Napp","year":"2015","unstructured":"Napp LC, Brehm M, K\u00fchn C, Sch\u00e4fer A, Bauersachs J (2015) Heart against veno-arterial ECMO: competition visualized. Int J Cardiol 187:164\u2013165. https:\/\/doi.org\/10.1016\/j.ijcard.2015.03.311","journal-title":"Int J Cardiol"},{"key":"3486_CR12","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1161\/CIRCULATIONAHA.114.011677","volume":"130","author":"MM Hoeper","year":"2014","unstructured":"Hoeper MM, Tudorache I, K\u00fchn C, Marsch G, Hartung D, Wiesner O et al (2014) Extracorporeal membrane oxygenation watershed. Circulation 130:864\u2013865. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.114.011677","journal-title":"Circulation"},{"key":"3486_CR13","doi-asserted-by":"publisher","first-page":"107","DOI":"10.5469\/neuroint.2023.00164","volume":"18","author":"KC Cho","year":"2023","unstructured":"Cho KC (2023) The current limitations and advanced analysis of hemodynamic study of cerebral aneurysms. Neurointervention 18:107\u2013113. https:\/\/doi.org\/10.5469\/neuroint.2023.00164","journal-title":"Neurointervention"},{"key":"3486_CR14","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.avsg.2019.04.032","volume":"63","author":"CW Ong","year":"2020","unstructured":"Ong CW, Wee I, Syn N, Ng S, Leo HL, Richards AM et al (2020) Computational fluid dynamics modeling of hemodynamic parameters in the human diseased aorta: a systematic review. Ann Vasc Surg 63:336\u2013381. https:\/\/doi.org\/10.1016\/j.avsg.2019.04.032","journal-title":"Ann Vasc Surg"},{"key":"3486_CR15","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1136935","author":"P Yevtushenko","year":"2023","unstructured":"Yevtushenko P, Goubergrits L, Franke B, Kuehne T, Schafstedde M (2023) Modelling blood flow in patients with heart valve disease using deep learning: a computationally efficient method to expand diagnostic capabilities in clinical routine. Front Cardiovasc Med. https:\/\/doi.org\/10.3389\/fcvm.2023.1136935","journal-title":"Front Cardiovasc Med"},{"key":"3486_CR16","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3134","author":"RM Romarowski","year":"2018","unstructured":"Romarowski RM, Lefieux A, Morganti S, Veneziani A, Auricchio F (2018) Patient-specific CFD modelling in the thoracic aorta with PC-MRI\u2013based boundary conditions: a least-square three-element Windkessel approach. Int J Numer Method Biomed Eng. https:\/\/doi.org\/10.1002\/cnm.3134","journal-title":"Int J Numer Method Biomed Eng"},{"key":"3486_CR17","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1002\/ccd.28507","volume":"95","author":"AK Armstrong","year":"2020","unstructured":"Armstrong AK, Zampi JD, Itu LM, Benson LN (2020) Use of 3D rotational angiography to perform computational fluid dynamics and virtual interventions in aortic coarctation. Catheter Cardiovasc Interv 95:294\u2013299. https:\/\/doi.org\/10.1002\/ccd.28507","journal-title":"Catheter Cardiovasc Interv"},{"key":"3486_CR18","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-018-0485-5","author":"Y Zhu","year":"2018","unstructured":"Zhu Y, Chen R, Juan YH, Li H, Wang J, Yu Z et al (2018) Clinical validation and assessment of aortic hemodynamics using computational fluid dynamics simulations from computed tomography angiography. Biomed Eng Online. https:\/\/doi.org\/10.1186\/s12938-018-0485-5","journal-title":"Biomed Eng Online"},{"key":"3486_CR19","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s12265-021-10110-2","volume":"15","author":"AR Prisco","year":"2022","unstructured":"Prisco AR, Aguado-Sierra J, Butakoff C, Vazquez M, Houzeaux G, Eguzkitza B et al (2022) Concomitant respiratory failure can impair myocardial oxygenation in patients with acute cardiogenic shock supported by VA-ECMO. J Cardiovasc Transl Res 15:217\u2013226. https:\/\/doi.org\/10.1007\/s12265-021-10110-2","journal-title":"J Cardiovasc Transl Res"},{"key":"3486_CR20","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1097\/MAT.0000000000001221","volume":"67","author":"FR Nezami","year":"2021","unstructured":"Nezami FR, Khodaee F, Edelman ER, Keller SP (2021) A computational fluid dynamics study of the extracorporeal membrane oxygenation-failing heart circulation. ASAIO J 67:276\u2013283. https:\/\/doi.org\/10.1097\/MAT.0000000000001221","journal-title":"ASAIO J"},{"key":"3486_CR21","doi-asserted-by":"publisher","first-page":"717","DOI":"10.12659\/MSM.895831","volume":"22","author":"K Gu","year":"2016","unstructured":"Gu K, Zhang Y, Gao B, Chang Y, Zeng Y (2016) Hemodynamic differences between central ECMO and peripheral ECMO: a primary CFD study. Med Sci Monit 22:717\u2013726. https:\/\/doi.org\/10.12659\/MSM.895831","journal-title":"Med Sci Monit"},{"key":"3486_CR22","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s12265-021-10143-7","volume":"15","author":"FR Nezami","year":"2022","unstructured":"Nezami FR, Ramezanpour M, Khodaee F, Goffer E, Edelman ER, Keller SP (2022) Simulation of fluid-structure interaction in extracorporeal membrane oxygenation circulatory support systems. J Cardiovasc Transl Res 15:249\u2013257. https:\/\/doi.org\/10.1007\/s12265-021-10143-7","journal-title":"J Cardiovasc Transl Res"},{"key":"3486_CR23","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jbiomech.2017.02.009","volume":"55","author":"MC Stevens","year":"2017","unstructured":"Stevens MC, Callaghan FM, Forrest P, Bannon PG, Grieve SM (2017) Flow mixing during peripheral veno-arterial extra corporeal membrane oxygenation \u2013 a simulation study. J Biomech 55:64\u201370. https:\/\/doi.org\/10.1016\/j.jbiomech.2017.02.009","journal-title":"J Biomech"},{"key":"3486_CR24","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1007\/BF01522036","volume":"17","author":"D Quemada","year":"1978","unstructured":"Quemada D (1978) Rheology of concentrated disperse systems II. a model for non-newtonian shear viscosity in steady flows. Rheol Acta 17:632\u2013642. https:\/\/doi.org\/10.1007\/BF01522036","journal-title":"Rheol Acta"},{"key":"3486_CR25","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/S1001-6058(16)60739-4","volume":"29","author":"A Skiadopoulos","year":"2017","unstructured":"Skiadopoulos A, Neofytou P, Housiadas C (2017) Comparison of blood rheological models in patient specific cardiovascular system simulations. J Hydrodyn 29:293\u2013304. https:\/\/doi.org\/10.1016\/S1001-6058(16)60739-4","journal-title":"J Hydrodyn"},{"key":"3486_CR26","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/BF01522037","volume":"17","author":"D Quemada","year":"1978","unstructured":"Quemada D (1978) Rheology of concentrated disperse systems III. General features of the proposed non-newtonian model. Comparison with experimental data. Rheol Acta 17:643\u2013653","journal-title":"Rheol Acta"},{"key":"3486_CR27","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-3273-2","volume-title":"Oxygen transport to Tissue \u2014 II","year":"1976","unstructured":"Grote J, Reneau D, Thews G (eds) (1976) Oxygen transport to Tissue \u2014 II, vol 75. Springer US, Boston, MA. https:\/\/doi.org\/10.1007\/978-1-4684-3273-2"},{"key":"3486_CR28","doi-asserted-by":"publisher","unstructured":"Chandra FA, Buzi G, Doyle JC (1979) Glycolytic oscillations and limits on robust efficiency. Science 2011;333:187\u201392. https:\/\/doi.org\/10.1126\/science.1200705","DOI":"10.1126\/science.1200705"},{"key":"3486_CR29","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1017\/jfm.2019.486","volume":"874","author":"JM Lopez","year":"2019","unstructured":"Lopez JM, Choueiri GH, Hof B (2019) Dynamics of viscoelastic pipe flow at low Reynolds numbers in the maximum drag reduction limit. J Fluid Mech 874:699\u2013719. https:\/\/doi.org\/10.1017\/jfm.2019.486","journal-title":"J Fluid Mech"},{"key":"3486_CR30","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1142\/S1758825109000095","volume":"01","author":"FPP TAN","year":"2009","unstructured":"TAN FPP, TORII R, BORGHI A, MOHIADDIN RH, WOOD NB, FLUID-STRUCTURE INTERACTION XUXY, ANALYSIS OF WALL STRESS AND FLOW PATTERNS IN A THORACIC AORTIC ANEURYSM (2009) Int J Appl Mech 01:179\u2013199. https:\/\/doi.org\/10.1142\/S1758825109000095","journal-title":"Int J Appl Mech"},{"key":"3486_CR31","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-018-0497-1","author":"S Madhavan","year":"2018","unstructured":"Madhavan S, Kemmerling EMC (2018) The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow. Biomed Eng Online. https:\/\/doi.org\/10.1186\/s12938-018-0497-1","journal-title":"Biomed Eng Online"},{"key":"3486_CR32","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s11517-008-0359-2","volume":"47","author":"N Westerhof","year":"2009","unstructured":"Westerhof N, Lankhaar JW, Westerhof BE (2009) The arterial Windkessel. Med Biol Eng Comput 47:131\u2013141. https:\/\/doi.org\/10.1007\/s11517-008-0359-2","journal-title":"Med Biol Eng Comput"},{"key":"3486_CR33","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.jbiomech.2017.06.005","volume":"60","author":"S Pirola","year":"2017","unstructured":"Pirola S, Cheng Z, Jarral OA, O\u2019Regan DP, Pepper JR, Athanasiou T et al (2017) On the choice of outlet boundary conditions for patient-specific analysis of aortic flow using computational fluid dynamics. J Biomech 60:15\u201321. https:\/\/doi.org\/10.1016\/j.jbiomech.2017.06.005","journal-title":"J Biomech"},{"key":"3486_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2024.108204","author":"Y Xi","year":"2024","unstructured":"Xi Y, Li Y, Wang H, Sun A, Deng X, Chen Z et al (2024) Effect of veno-arterial extracorporeal membrane oxygenation lower-extremity cannulation on intra-arterial flow characteristics, oxygen content, and thrombosis risk. Comput Methods Programs Biomed. https:\/\/doi.org\/10.1016\/j.cmpb.2024.108204","journal-title":"Comput Methods Programs Biomed"},{"key":"3486_CR35","doi-asserted-by":"publisher","first-page":"657","DOI":"10.4070\/kcj.2019.0188","volume":"49","author":"MS Choi","year":"2019","unstructured":"Choi MS, Sung K, Cho YH (2019) Clinical pearls of venoarterial extracorporeal membrane oxygenation for cardiogenic shock. Korean Circ J 49:657\u2013677. https:\/\/doi.org\/10.4070\/kcj.2019.0188","journal-title":"Korean Circ J"},{"key":"3486_CR36","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.ijcard.2019.01.092","volume":"281","author":"N Grande Gutierrez","year":"2019","unstructured":"Grande Gutierrez N, Mathew M, McCrindle BW, Tran JS, Kahn AM, Burns JC et al (2019) Hemodynamic variables in aneurysms are associated with thrombotic risk in children with Kawasaki disease. Int J Cardiol 281:15\u201321. https:\/\/doi.org\/10.1016\/j.ijcard.2019.01.092","journal-title":"Int J Cardiol"},{"key":"3486_CR37","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1177\/15266028221091890","volume":"30","author":"L van de Velde","year":"2023","unstructured":"van de Velde L, Groot Jebbink E, Hagmeijer R, Versluis M, Reijnen MMPJ (2023) Computational fluid dynamics for the prediction of endograft thrombosis in the superficial femoral artery. J Endovasc Ther 30:615\u2013627. https:\/\/doi.org\/10.1177\/15266028221091890","journal-title":"J Endovasc Ther"},{"key":"3486_CR38","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1111\/j.1525-1594.2009.00930.x","volume":"34","author":"SC Corbett","year":"2010","unstructured":"Corbett SC, Ajdari A, Coskun AU, N-Hashemi H (2010) In vitro and computational thrombosis on artificial surfaces with shear stress. Artif Organs 34:561\u2013569. https:\/\/doi.org\/10.1111\/j.1525-1594.2009.00930.x","journal-title":"Artif Organs"},{"key":"3486_CR39","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/s10047-013-0694-4","volume":"16","author":"C Konoura","year":"2013","unstructured":"Konoura C, Yagi T, Nakamura M, Iwasaki K, Qian Y, Okuda S et al (2013) Numerical analysis of blood flow distribution in 4- and 3-branch vascular grafts. J Artif Organs 16:157\u2013163. https:\/\/doi.org\/10.1007\/s10047-013-0694-4","journal-title":"J Artif Organs"},{"key":"3486_CR40","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2020.03.186","volume":"8","author":"Y Su","year":"2020","unstructured":"Su Y, Liu K, Zheng J-L, Li X, Zhu D-M, Zhang Y et al (2020) Hemodynamic monitoring in patients with venoarterial extracorporeal membrane oxygenation. Ann Transl Med 8:792\u2013792. https:\/\/doi.org\/10.21037\/atm.2020.03.186","journal-title":"Ann Transl Med"},{"key":"3486_CR41","unstructured":"IEEE Instrumentation (2008) & measurement magazine the measurement of oxygen saturation in arterial and venous blood"},{"key":"3486_CR42","doi-asserted-by":"publisher","first-page":"1470","DOI":"10.1007\/s00134-024-07564-8","volume":"50","author":"A Burrell","year":"2024","unstructured":"Burrell A, Bailey MJ, Bellomo R, Buscher H, Eastwood G, Forrest P et al (2024) Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation. Intensive Care Med 50:1470\u20131483. https:\/\/doi.org\/10.1007\/s00134-024-07564-8","journal-title":"Intensive Care Med"},{"key":"3486_CR43","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1051\/ject\/201345183","volume":"45","author":"DV Avgerinos","year":"2013","unstructured":"Avgerinos DV, DeBois W, Voevidko L, Salemi A (2013) Regional variation in arterial saturation and oxygen delivery during venoarterial extracorporeal membrane oxygenation. J Extra Corpor Technol 45:183\u2013186","journal-title":"J Extra Corpor Technol"},{"key":"3486_CR44","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(22)03691-9","volume":"79","author":"A Karan","year":"2022","unstructured":"Karan A, Mgbemena O, Rollini F, Al-Turk B, Liu K, Rivas J et al (2022) Percutaneous ECMO-associated harlequin (north-south) syndrome following V-A ECMO initiation. J Am Coll Cardiol 79:2700. https:\/\/doi.org\/10.1016\/s0735-1097(22)03691-9","journal-title":"J Am Coll Cardiol"},{"key":"3486_CR45","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7509","author":"C Karam","year":"2023","unstructured":"Karam C, Abou Nafeh N, Aouad MT, Siddik-Sayyid S, Kaddoum R, Zeeni C et al (2023) Harlequin syndrome during peripheral cardiopulmonary bypass in a patient with an obstructing tracheal schwannoma: a case report. Clin Case Rep. https:\/\/doi.org\/10.1002\/ccr3.7509","journal-title":"Clin Case Rep"},{"key":"3486_CR46","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-9-55","author":"JH Choi","year":"2014","unstructured":"Choi JH, Kim SW, Kim YU, Kim SY, Kim KS, Joo SJ et al (2014) Application of veno-arterial-venous extracorporeal membrane oxygenation in differential hypoxia. Multidiscip Respir Med. https:\/\/doi.org\/10.1186\/2049-6958-9-55","journal-title":"Multidiscip Respir Med"},{"key":"3486_CR47","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1111\/aor.14610","volume":"47","author":"A Saxena","year":"2023","unstructured":"Saxena A, Curran J, Ahmad D, Nasher N, Miyamoto T, Brailovsky E et al (2023) Utilization and outcomes of V-AV ECMO: A systematic review and meta-analysis. Artif Organs 47:1559\u20131566. https:\/\/doi.org\/10.1111\/aor.14610","journal-title":"Artif Organs"},{"key":"3486_CR48","doi-asserted-by":"publisher","first-page":"274","DOI":"10.5090\/jcs.22.151","volume":"56","author":"HJ Cha","year":"2023","unstructured":"Cha HJ, Kim JW, Kang DH, Moon SH, Kim SH, Jung JJ et al (2023) Conversion to veno-arteriovenous extracorporeal membrane oxygenation for differential hypoxia. J Chest Surg 56:274\u2013281. https:\/\/doi.org\/10.5090\/jcs.22.151","journal-title":"J Chest Surg"},{"key":"3486_CR49","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1111\/jocs.16348","volume":"37","author":"C Kukielski","year":"2022","unstructured":"Kukielski C, Jarrett Davis C, Saberi A, Chaudhary S (2022) Veno-arteriovenous (V-AV) ECMO configuration: A single-center experience. J Card Surg 37:1254\u20131261. https:\/\/doi.org\/10.1111\/jocs.16348","journal-title":"J Card Surg"},{"key":"3486_CR50","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1051\/ject\/201648162","volume":"48","author":"B Williams","year":"2016","unstructured":"Williams B, Bernstein W (2016) Review of venoarterial extracorporeal membrane oxygenation and development of intracardiac thrombosis in adult cardiothoracic patients. J Extra Corpor Technol 48:162\u2013167","journal-title":"J Extra Corpor Technol"},{"key":"3486_CR51","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.116.003757","author":"M Alhussein","year":"2017","unstructured":"Alhussein M, Moayedi Y, Posada JD, Ross H, Hickey E, Rao V et al (2017) Ventricular thrombosis post-venoarterial extracorporeal membrane oxygenation. Circ Heart Fail. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.116.003757","journal-title":"Circ Heart Fail"},{"key":"3486_CR52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-87026-z","author":"B Cartwright","year":"2021","unstructured":"Cartwright B, Bruce HM, Kershaw G, Cai N, Othman J, Gattas D et al (2021) Hemostasis, coagulation and thrombin in venoarterial and venovenous extracorporeal membrane oxygenation: the HECTIC study. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-021-87026-z","journal-title":"Sci Rep"},{"key":"3486_CR53","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12031082","author":"S Rajsic","year":"2023","unstructured":"Rajsic S, Breitkopf R, Rugg C, Bukumiric Z, Reitbauer J, Treml B (2023) Thrombotic events develop in 1 out of 5 patients receiving ECMO support: an 11-year referral centre experience. J Clin Med. https:\/\/doi.org\/10.3390\/jcm12031082","journal-title":"J Clin Med"},{"key":"3486_CR54","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1177\/039139880602901205","volume":"29","author":"AJ Rastan","year":"2006","unstructured":"Rastan AJ, Lachmann N, Walther T, Doll N, Gradistanac T, Gommert JF et al (2006) Autopsy findings in patients on postcardiotomy extracorporeal membrane oxygenation (ECMO). Int J Artif Organs 29:1121\u20131131. https:\/\/doi.org\/10.1177\/039139880602901205","journal-title":"Int J Artif Organs"},{"key":"3486_CR55","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.thromres.2022.02.015","volume":"212","author":"A Abruzzo","year":"2022","unstructured":"Abruzzo A, Gorantla V, Thomas SE (2022) Venous thromboembolic events in the setting of extracorporeal membrane oxygenation support in adults: a systematic review. Thromb Res 212:58\u201371. https:\/\/doi.org\/10.1016\/j.thromres.2022.02.015","journal-title":"Thromb Res"},{"key":"3486_CR56","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1111\/jth.15784","volume":"20","author":"S Staessens","year":"2022","unstructured":"Staessens S, Moussa MD, Pierache A, Rauch A, Rousse N, Boulleaux E et al (2022) Thrombus formation during ECMO: insights from a detailed histological analysis of thrombus composition. J Thromb Haemost 20:2058\u20132069. https:\/\/doi.org\/10.1111\/jth.15784","journal-title":"J Thromb Haemost"},{"key":"3486_CR57","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-020-01239-3","author":"T Nishihara","year":"2020","unstructured":"Nishihara T, Kudamatsu N, Hamada T, Nakata Y, Yamamoto W, Nandate H et al (2020) A case report of thrombotic complete obstruction of the ascending aorta as a complication of venoarterial extracorporeal membrane oxygenation support: steps to prevent thrombosis. J Cardiothorac Surg. https:\/\/doi.org\/10.1186\/s13019-020-01239-3","journal-title":"J Cardiothorac Surg"},{"key":"3486_CR58","doi-asserted-by":"crossref","unstructured":"Steffens JC, Bourne MW, Sakuma H, O\u2019sullivan M, Higgins CB (1994) Quantification of collateral blood flow in coarctation of the aorta by velocity encoded cine magnetic resonance imaging","DOI":"10.1161\/01.CIR.90.2.937"},{"issue":"7","key":"3486_CR59","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1007\/s10439-023-03175-4","volume":"51","author":"C Stokes","year":"2023","unstructured":"Stokes C, Haupt F, Becker D, Muthurangu V, von Tengg-Kobligk H, Balabani S et al (2023) The influence of minor aortic branches in patient-specific flow simulations of type-B aortic dissection. Ann Biomed Eng 51(7):1627\u20131644. https:\/\/doi.org\/10.1007\/s10439-023-03175-4","journal-title":"Ann Biomed Eng"},{"key":"3486_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2024.104263","author":"X Wu","year":"2025","unstructured":"Wu X, Jansen KMB, Westenberg JJM, Lamb HJ, Kenjere\u0161 S (2025) Aortic strain, flow pattern and wall shear stress in a patient-specific compliant aorta replica using Shake-the-Box. Med Eng Phys. https:\/\/doi.org\/10.1016\/j.medengphy.2024.104263","journal-title":"Med Eng Phys"},{"key":"3486_CR61","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1016\/j.jtcvs.2018.08.081","volume":"156","author":"M Sch\u00e4fer","year":"2018","unstructured":"Sch\u00e4fer M, Browne LP, Morgan GJ, Barker AJ, Fonseca B, Ivy DD et al (2018) Reduced proximal aortic compliance and elevated wall shear stress after early repair of tetralogy of fallot. J Thorac Cardiovasc Surg 156:2239\u20132249. https:\/\/doi.org\/10.1016\/j.jtcvs.2018.08.081","journal-title":"J Thorac Cardiovasc Surg"},{"key":"3486_CR62","doi-asserted-by":"publisher","unstructured":"Carvalho V, Lopes D, Silva J, Puga H, Lima A, Carlos Teixeira R et al (2022) J,. Comparison of CFD and FSI Simulations of Blood Flow in Stenotic Coronary Arteries. Applications of Computational Fluid Dynamics Simulation and Modeling, IntechOpen; https:\/\/doi.org\/10.5772\/intechopen.102089","DOI":"10.5772\/intechopen.102089"},{"key":"3486_CR63","doi-asserted-by":"publisher","DOI":"10.1002\/cnm.3630","author":"D Jodko","year":"2022","unstructured":"Jodko D, Jeckowski M, Tyfa Z (2022) Fluid structure interaction versus rigid-wall approach in the study of the symptomatic stenosed carotid artery: importance of wall compliance and resilience of loose connective tissue. Int J Numer Method Biomed Eng. https:\/\/doi.org\/10.1002\/cnm.3630","journal-title":"Int J Numer Method Biomed Eng"}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03486-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s11517-025-03486-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-025-03486-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T04:25:59Z","timestamp":1772252759000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s11517-025-03486-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,15]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["3486"],"URL":"https:\/\/doi.org\/10.1007\/s11517-025-03486-9","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,15]]},"assertion":[{"value":"15 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}