{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:50:57Z","timestamp":1790430657392,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:00:00Z","timestamp":1513814400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J CARS"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1007\/s11548-017-1691-5","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:53:10Z","timestamp":1513817590000},"page":"563-571","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":81,"title":["MRI radiomics analysis of molecular alterations in low-grade gliomas"],"prefix":"10.1007","volume":"13","author":[{"given":"Ben","family":"Shofty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moran","family":"Artzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8396-1031","authenticated-orcid":false,"given":"Dafna","family":"Ben\u00a0Bashat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilad","family":"Liberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oz","family":"Haim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alon","family":"Kashanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Bokstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah T.","family":"Blumenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvi","family":"Ram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal","family":"Shahar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,12,21]]},"reference":[{"key":"1691_CR1","unstructured":"Cancer Genome Atlas Research N, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O\u2019Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T Jr, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG Jr, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, McLendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang J (2015) Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 372(26):2481\u20132498"},{"issue":"5897","key":"1691_CR2","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1126\/science.1164382","volume":"321","author":"DW Parsons","year":"2008","unstructured":"Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA Jr, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321(5897):1807\u201312","journal-title":"Science"},{"issue":"8","key":"1691_CR3","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1056\/NEJMoa0808710","volume":"360","author":"H Yan","year":"2009","unstructured":"Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, Velculescu VE, Vogelstein B, Bigner DD (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360(8):765\u2013773","journal-title":"N Engl J Med"},{"issue":"5","key":"1691_CR4","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s11910-013-0345-4","volume":"13","author":"AL Cohen","year":"2013","unstructured":"Cohen AL, Holmen SL, Colman H (2013) IDH1 and IDH2 mutations in gliomas. Curr Neurol Neurosci Rep 13(5):345","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"7","key":"1691_CR5","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1038\/modpathol.2012.166","volume":"26","author":"SH Boots-Sprenger","year":"2013","unstructured":"Boots-Sprenger SH, Sijben A, Rijntjes J, Tops BB, Idema AJ, Rivera AL, Bleeker FE, Gijtenbeek AM, Diefes K, Heathcock L, Aldape KD, Jeuken JW, Wesseling P (2013) Significance of complete 1p\/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution. Mod Pathol 26(7):922\u20139","journal-title":"Mod Pathol"},{"issue":"2","key":"1691_CR6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11060-015-1906-y","volume":"125","author":"MC Chamberlain","year":"2015","unstructured":"Chamberlain MC, Born D (2015) Prognostic significance of relative 1p\/19q codeletion in oligodendroglial tumors. J Neuro Oncol 125(2):249\u2013251","journal-title":"J Neuro Oncol"},{"issue":"6","key":"1691_CR7","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","volume":"131","author":"DN Louis","year":"2016","unstructured":"Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131(6):803\u2013820","journal-title":"Acta Neuropathol"},{"issue":"2","key":"1691_CR8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/neuonc\/nov307","volume":"18","author":"I Macarena","year":"2016","unstructured":"Macarena I, Young RJ, Rubel J, Rosenblum M, Tisnado J, Briggs S, Arevalo-Perez J, Cross JR, Campos C, Straley K (2016) Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma. Neuro Oncology 18(2):283\u2013290","journal-title":"Neuro Oncology"},{"issue":"1","key":"1691_CR9","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s11060-011-0737-8","volume":"107","author":"WB Pope","year":"2012","unstructured":"Pope WB, Prins RM, Thomas MA, Nagarajan R, Yen KE, Bittinger MA, Salamon N, Chou AP, Yong WH, Soto H (2012) Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy. J Neuro Oncol 107(1):197\u2013205","journal-title":"J Neuro Oncol"},{"issue":"9","key":"1691_CR10","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1172\/JCI67229","volume":"123","author":"OC Andronesi","year":"2013","unstructured":"Andronesi OC, Rapalino O, Gerstner E, Chi A, Batchelor TT, Cahill DP, Sorensen AG, Rosen BR (2013) Detection of oncogenic IDH1 mutations using magnetic resonance spectroscopy of 2-hydroxyglutarate. J Clin Investig 123(9):3659\u20133663","journal-title":"J Clin Investig"},{"issue":"1","key":"1691_CR11","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s11060-014-1614-z","volume":"121","author":"S Lee","year":"2015","unstructured":"Lee S, Choi SH, Ryoo I, Yoon TJ, Kim TM, Lee S-H, Park C-K, Kim J-H, Sohn C-H, Park S-H (2015) Evaluation of the microenvironmental heterogeneity in high-grade gliomas with IDH1\/2 gene mutation using histogram analysis of diffusion-weighted imaging and dynamic-susceptibility contrast perfusion imaging. J Neuro Oncol 121(1):141\u2013150","journal-title":"J Neuro Oncol"},{"issue":"1","key":"1691_CR12","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3174\/ajnr.A4491","volume":"37","author":"K Yamashita","year":"2016","unstructured":"Yamashita K, Hiwatashi A, Togao O, Kikuchi K, Hatae R, Yoshimoto K, Mizoguchi M, Suzuki S, Yoshiura T, Honda H (2016) MR imaging-based analysis of glioblastoma multiforme: estimation of IDH1 mutation status. Am J Neuroradiol 37(1):58\u201365","journal-title":"Am J Neuroradiol"},{"issue":"8","key":"1691_CR13","doi-asserted-by":"crossref","first-page":"3509","DOI":"10.1007\/s00330-016-4653-3","volume":"27","author":"J Yu","year":"2017","unstructured":"Yu J, Shi Z, Lian Y, Li Z, Liu T, Gao Y, Wang Y, Chen L, Mao Y (2017) Noninvasive IDH1 mutation estimation based on a quantitative radiomics approach for grade II glioma. Eur Radiol 27(8):3509\u20133522","journal-title":"Eur Radiol"},{"issue":"1","key":"1691_CR14","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/neuonc\/now121","volume":"19","author":"B Zhang","year":"2017","unstructured":"Zhang B, Chang K, Ramkissoon S, Tanguturi S, Bi WL, Reardon DA, Ligon KL, Alexander BM, Wen PY, Huang RY (2017) Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas. Neuro Oncology 19(1):109\u2013117","journal-title":"Neuro Oncology"},{"key":"1691_CR15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1142\/S0219635216500011","volume":"2017","author":"J Yu","year":"2016","unstructured":"Yu J, Shi Z, Ji C, Lian Y, Wang Y, Chen L, Mao Y (2016) Anatomical location differences between mutated and wild-type isocitrate dehydrogenase 1 in low-grade gliomas. Int J Neurosci 2017:1\u20138","journal-title":"Int J Neurosci"},{"key":"1691_CR16","unstructured":"Akkus Z, Ali I, Sedlar J, Kline TL, Agrawal JP, Parney IF, Giannini C, Erickson BJ (2016) Predicting 1p19q chromosomal deletion of low-grade gliomas from MR images using deep learning. arXiv preprint arXiv:1611.06939"},{"issue":"6","key":"1691_CR17","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/neuonc\/now256","volume":"19","author":"H Zhou","year":"2017","unstructured":"Zhou H, Valli\u00e8res M, Bai HX, Su C, Tang H, Oldridge D, Zhang Z, Xiao B, Liao W, Tao Y (2017) MRI features predict survival and molecular markers in diffuse lower-grade gliomas. Neuro Oncology 19(6):862\u2013870","journal-title":"Neuro Oncology"},{"issue":"5","key":"1691_CR18","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1038\/ncomms5006","volume":"3","author":"HJ Aerts","year":"2014","unstructured":"Aerts HJ, Velazquez ER, Leijenaar RT, Parmar C, Grossmann P, Carvalho S, Bussink J, Monshouwer R, Haibe-Kains B, Rietveld D (2014) Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach. Nat Commun 3(5):4006","journal-title":"Nat Commun"},{"issue":"4","key":"1691_CR19","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.ejca.2011.11.036","volume":"48","author":"P Lambin","year":"2012","unstructured":"Lambin P, Rios-Velazquez E, Leijenaar R, Carvalho S, van Stiphout RG, Granton P, Zegers CM, Gillies R, Boellard R, Dekker A (2012) Radiomics: extracting more information from medical images using advanced feature analysis. Eur J Cancer 48(4):441\u2013446","journal-title":"Eur J Cancer"},{"issue":"2","key":"1691_CR20","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1148\/radiol.2015151169","volume":"278","author":"RJ Gillies","year":"2015","unstructured":"Gillies RJ, Kinahan PE, Hricak H (2015) Radiomics: images are more than pictures, they are data. Radiology 278(2):563\u2013577","journal-title":"Radiology"},{"issue":"4","key":"1691_CR21","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.mric.2016.06.006","volume":"24","author":"A Kotrotsou","year":"2016","unstructured":"Kotrotsou A, Zinn PO, Colen RR (2016) Radiomics in brain tumors: an emerging technique for characterization of tumor environment. Magn Reson Imaging Clin N Am 24(4):719\u2013729","journal-title":"Magn Reson Imaging Clin N Am"},{"issue":"2","key":"1691_CR22","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/neuonc\/nop041","volume":"12","author":"I Lavon","year":"2010","unstructured":"Lavon I, Refael M, Zelikovitch B, Shalom E, Siegal T (2010) Serum DNA can define tumor-specific genetic and epigenetic markers in gliomas of various grades. Neuro Oncology 12(2):173\u2013180","journal-title":"Neuro Oncology"},{"issue":"2","key":"1691_CR23","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S1361-8415(01)00036-6","volume":"5","author":"M Jenkinson","year":"2001","unstructured":"Jenkinson M, Smith S (2001) A global optimisation method for robust affine registration of brain images. Med Image Anal 5(2):143\u2013156","journal-title":"Med Image Anal"},{"issue":"3","key":"1691_CR24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/hbm.10062","volume":"17","author":"SM Smith","year":"2002","unstructured":"Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17(3):143\u2013155","journal-title":"Hum Brain Mapp"},{"issue":"1","key":"1691_CR25","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1109\/42.906424","volume":"20","author":"Y Zhang","year":"2001","unstructured":"Zhang Y, Brady M, Smith S (2001) Segmentation of brain MR images through a hidden Markov random field model and the expectation\u2013maximization algorithm. IEEE Trans Med Imaging 20(1):45\u201357","journal-title":"IEEE Trans Med Imaging"},{"key":"1691_CR26","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1109\/TSMC.1973.4309314","volume":"6","author":"RM Haralick","year":"1973","unstructured":"Haralick RM, Shanmugam K (1973) Textural features for image classification. IEEE Trans Syst Man Cybern 6:610\u2013621","journal-title":"IEEE Trans Syst Man Cybern"},{"issue":"3","key":"1691_CR27","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1148\/radiol.2016161382","volume":"281","author":"P Kickingereder","year":"2016","unstructured":"Kickingereder P, Bonekamp D, Nowosielski M, Kratz A, Sill M, Burth S, Wick A, Eidel O, Schlemmer HP, Radbruch A, Debus J, Herold-Mende C, Unterberg A, Jones D, Pfister S, Wick W, von Deimling A, Bendszus M, Capper D (2016) Radiogenomics of glioblastoma: machine learning-based classification of molecular characteristics by using multiparametric and multiregional MR imaging features. Radiology 281(3):907\u2013918","journal-title":"Radiology"},{"issue":"5","key":"1691_CR28","doi-asserted-by":"crossref","first-page":"809","DOI":"10.3174\/ajnr.A2061","volume":"31","author":"A Kassner","year":"2010","unstructured":"Kassner A, Thornhill RE (2010) Texture analysis: a review of neurologic MR imaging applications. AJNR Am J Neuroradiol 31(5):809\u2013816","journal-title":"AJNR Am J Neuroradiol"},{"issue":"4","key":"1691_CR29","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.ejrad.2016.01.013","volume":"85","author":"K Skogen","year":"2016","unstructured":"Skogen K, Schulz A, Dormagen JB, Ganeshan B, Helseth E, Server A (2016) Diagnostic performance of texture analysis on MRI in grading cerebral gliomas. Eur J Radiol 85(4):824\u2013829","journal-title":"Eur J Radiol"},{"key":"1691_CR30","doi-asserted-by":"crossref","unstructured":"Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, Barbaro NM, Parsa AT, Berger MS, Mcdermott MM (2008) Preoperative prognostic classification system for hemispheric low-grade gliomas in adults. J Neurosurg 109(5):817\u2013824","DOI":"10.3171\/JNS\/2008\/109\/11\/0817"},{"issue":"18","key":"1691_CR31","first-page":"6713","volume":"61","author":"MC Zlatescu","year":"2001","unstructured":"Zlatescu MC, TehraniYazdi A, Sasaki H, Megyesi JF, Betensky RA, Louis DN, Cairncross JG (2001) Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms. Cancer Res 61(18):6713\u20136715","journal-title":"Cancer Res"}],"container-title":["International Journal of Computer Assisted Radiology and Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11548-017-1691-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11548-017-1691-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11548-017-1691-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T06:41:42Z","timestamp":1570516902000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11548-017-1691-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,21]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["1691"],"URL":"https:\/\/doi.org\/10.1007\/s11548-017-1691-5","relation":{},"ISSN":["1861-6410","1861-6429"],"issn-type":[{"value":"1861-6410","type":"print"},{"value":"1861-6429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,21]]}}}