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Even the Information Systems (IS) discipline with its close connections to Computer Science seems to be conservative when conducting empirical research endeavors. To assess the magnitude of the problem and to understand its causes, we conducted a bibliographic review on publications in high-level IS journals. We reviewed 1,838 articles that matched corresponding keyword-queries in journals from the AIS senior scholar basket, Electronic Markets and Decision Support Systems (Ranked B). In addition, we conducted a survey among IS researchers (N = 110). Based on the findings from our sample we evaluate different potential causes that could explain why ML methods are rather underrepresented in top-tier journals and discuss how the IS discipline could successfully incorporate ML methods in research undertakings.<\/jats:p>","DOI":"10.1007\/s12525-021-00459-2","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T03:48:01Z","timestamp":1618890481000},"page":"643-670","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Machine learning in information systems - a bibliographic review and open research issues"],"prefix":"10.1007","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2588-6552","authenticated-orcid":false,"given":"Benjamin M.","family":"Abdel-Karim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Pfeuffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Hinz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"issue":"2","key":"459_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.17705\/1jais.00423","volume":"17","author":"A Abbasi","year":"2016","unstructured":"Abbasi, A., Sarker, S., & Chiang, R.H. 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