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Multimed Tools Appl, 1\u2013112 2024). This problem is even greater in developing countries. In recent years, diagnostic tools based on artificial intelligence techniques have been developed to improve diagnosis time and results. In this work, we present a system that analyzes histopathological images obtained from breast tissue biopsies to design a classification system that distinguishes between benign and malignant tissue. To demonstrate that the proposed work is robust, multiple alternatives and combinations are studied to obtain the best cases. Finally, we compare the proposed approach with previous works. Furthermore, the developed system integrates explainable artificial intelligence techniques to produce a report to the physician, including a heat map with the areas the system has determined to be essential for classification.<\/jats:p>","DOI":"10.1007\/s12559-025-10510-5","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T10:41:34Z","timestamp":1758710494000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Explainable Deep Learning System for Custom Report Generation in Breast Cancer Histology"],"prefix":"10.1007","volume":"17","author":[{"given":"Miguel\u00a0\u00c1ngel","family":"Anguita-Molina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Civit-Masot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Mu\u00f1oz-Saavedra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Polo-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Dom\u00ednguez-Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"10510_CR1","doi-asserted-by":"crossref","unstructured":"Sharafaddini AM, Esfahani KK, Mansouri N. 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