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This progress promotes individualized medicine, where treatment and care are tailored to each patient\u2019s unique needs and characteristics. The Theory of Tailorable Technology Design has considerable potential to contribute to individualized medicine as it focuses on information systems (IS) that users can modify and redesign in the context of use. While the theory accounts for both the designer and user perspectives in the lifecycle of an IS, it does not reflect the inductive learning and autonomy of AI throughout the tailoring process. Therefore, this study posits the conjecture that current knowledge about tailorable technology design does not effectively account for IS that incorporate AI. To investigate this conjecture and challenge the Theory of Tailorable Technology Design, a revelatory design study of an AI-enabled individual IS in the domain of bladder monitoring is conducted. Based on the empirical evidence from the design study, the primary contribution of this work lies in three propositions for the design of tailorable technology, culminating in a Revised Theory of Tailorable Technology Design. As the outcome of the design study, the secondary contribution of this work is concrete design knowledge for AI-enabled individualized bladder monitoring systems that empower patients with neurogenic lower urinary tract dysfunction (NLUTD). Overall, this study highlights the value of AI for patient-centeredness in IS design.<\/jats:p>","DOI":"10.1007\/s12599-024-00872-9","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T18:03:42Z","timestamp":1716919422000},"page":"357-376","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["How Artificial Intelligence Challenges Tailorable Technology Design"],"prefix":"10.1007","volume":"66","author":[{"given":"Pascal","family":"Fechner","sequence":"first","affiliation":[]},{"given":"Fabian","family":"K\u00f6nig","sequence":"additional","affiliation":[]},{"given":"Jannik","family":"Lockl","sequence":"additional","affiliation":[]},{"given":"Maximilian","family":"R\u00f6glinger","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"872_CR1","unstructured":"Abadi M, Agarwal A, Barham P, Brevdo E, Chen Z, Citro C, Corrado GS, Davis A, Dean J, Devin M, Ghemawat S, Goodfellow I, Harp A, Irving G, Isard M, Jia Y, Jozefowicz R, Kaiser L, Kudlur M, Levenberg J, Man\u00e9 D, Monga R, Moore S, Murray D, Olah C, Schuster M, Shlens J, Steiner B, Sutskever I, Talwar K, Tucker P, Vanhoucke V, Vasudevan V, Vi\u00e9gas F, Vinyals O, Warden P, Wattenberg M, Wicke M, Yu Y, Zheng X (2015) TensorFlow: large-scale machine learning on heterogeneous systems. https:\/\/www.tensorflow.org\/"},{"key":"872_CR2","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1080\/0960085X.2021.1876534","volume":"31","author":"M Abouzahra","year":"2022","unstructured":"Abouzahra M, Ghasemaghaei M (2022) Effective use of information technologies by seniors: the case of wearable device use. 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