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Many medical devices are available in the medical field; however, medical errors remain a severe challenge. Different algorithms are developed to identify and solve medical errors, such as detecting anomalous readings, anomalous health conditions of a patient, etc. However, they fail to answer why those entries are considered an anomaly. This research gap leads to an outlying aspect mining problem. The problem of outlying aspect mining aims to discover the set of features (a.k.a subspace) in which the given data point is dramatically different than others. In this paper, we present a framework that detects anomalies in healthcare data and then provides an explanation of anomalies. This paper aims to effectively and efficiently detect anomalies and explain why they are considered anomalies by detecting outlying aspects. First, we re-introduced four anomaly detection techniques and outlying aspect mining algorithms. Then, we evaluate the performance of anomaly detection techniques and choose the best anomaly detection algorithm. Later, we detect the top <jats:italic>k<\/jats:italic> anomaly as a query and detect their outlying aspect. Lastly, we evaluate their performance on 16 real-world healthcare datasets. The experimental results show that the latest isolation-based outlying aspect mining measure, SiNNE, has outstanding performance on this task and has promising results.<\/jats:p>","DOI":"10.1007\/s13755-023-00221-2","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T10:02:53Z","timestamp":1680775373000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Detection and explanation of anomalies in healthcare data"],"prefix":"10.1007","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1042-7804","authenticated-orcid":false,"given":"Durgesh","family":"Samariya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Aryal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"221_CR1","unstructured":"Hauskrecht M, Valko M, Batal I, et\u00a0al. 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