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Then, the Local Directional Number method (LDN) is used for representing some key information in a new image. Finally, a cascade Convolutional Neural Network (CNN) is employed for nerve optic segmentation by two distinct input images. Comprehensive experiments on the CT screening dataset [The Cancer Imaging Archive (TCIA)] consisting of 1600 images show the competitive results of inaccurate extraction of the brain features. Also, the indexes such as Dice, Specificity, and Precision for the proposed approach are reported 87.7%, 91.3%, and 90.1%, respectively. The final classification results show that the proposed approach effectively and accurately detects the nerve optic and its diameter in comparison with the other methods. Therefore, this method can be used for early diagnose of ICP and preventing the occurrence of serious health problems in patients.<\/jats:p>","DOI":"10.1007\/s40747-022-00694-w","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T08:02:43Z","timestamp":1646035363000},"page":"3543-3557","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Nerve optic segmentation in CT images using a deep learning model and a texture descriptor"],"prefix":"10.1007","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7065-9060","authenticated-orcid":false,"given":"Ramin","family":"Ranjbarzadeh","sequence":"first","affiliation":[]},{"given":"Shadi","family":"Dorosti","sequence":"additional","affiliation":[]},{"given":"Saeid","family":"Jafarzadeh Ghoushchi","sequence":"additional","affiliation":[]},{"given":"Sadaf","family":"Safavi","sequence":"additional","affiliation":[]},{"given":"Navid","family":"Razmjooy","sequence":"additional","affiliation":[]},{"given":"Nazanin","family":"Tataei Sarshar","sequence":"additional","affiliation":[]},{"given":"Shokofeh","family":"Anari","sequence":"additional","affiliation":[]},{"given":"Malika","family":"Bendechache","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"issue":"1","key":"694_CR1","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s12987-020-00201-8","volume":"17","author":"N Canac","year":"2020","unstructured":"Canac N, Jalaleddini K, Thorpe SG, Thibeault CM, Hamilton RB (2020) Review: pathophysiology of intracranial hypertension and noninvasive intracranial pressure monitoring. 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