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Leveraging on synthetic data, we represent the outcome trajectories of some sample patients for 1-year continuous monitoring and discuss approaches to characterize them based on the exhibited tendency and evaluate the results from the predictability point of view providing by the <jats:italic>entropy<\/jats:italic> of time series concept. At the end, we discuss the possible data quality issues in health care studies using synthetic data.<\/jats:p>","DOI":"10.1007\/s40747-022-00775-w","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T09:02:46Z","timestamp":1654074166000},"page":"3953-3971","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A methodology to engineering continuous monitoring of intrinsic capacity for elderly people"],"prefix":"10.1007","volume":"8","author":[{"given":"Valerio","family":"Bellandi","sequence":"first","affiliation":[]},{"given":"Paolo","family":"Ceravolo","sequence":"additional","affiliation":[]},{"given":"Ernesto","family":"Damiani","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8310-2050","authenticated-orcid":false,"given":"Samira","family":"Maghool","sequence":"additional","affiliation":[]},{"given":"Matteo","family":"Cesari","sequence":"additional","affiliation":[]},{"given":"Ioannis","family":"Basdekis","sequence":"additional","affiliation":[]},{"given":"Eleftheria","family":"Iliadou","sequence":"additional","affiliation":[]},{"given":"Mircea Dan","family":"Marzan","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2022,6,1]]},"reference":[{"key":"775_CR1","doi-asserted-by":"crossref","unstructured":"Basdekis I, Pozdniakov K, Prasinos M, Koloutsou K (2019) Evidence based public health policy making: tool support. 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No financial support or benefits have been received by the authors, by any member of my immediate family of the authors, or any individual or entity with whom or with which the authors have a significant relationship from any commercial source which is related directly or indirectly to the scientific work which is reported on in the article except as described below.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}