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Syst."],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fundus image captures rear of an eye which has been studied for disease identification, classification, segmentation, generation, and biological traits association using handcrafted, conventional, and deep learning methods. In biological traits estimation, most of the studies have been carried out for the age prediction and gender classification with convincing results. The current study utilizes the cutting-edge deep learning (DL) algorithms to estimate biological traits in terms of age and gender together with associating traits to retinal visuals. For the trait\u2019s association, we embed aging as the label information into the proposed DL model to learn knowledge about the effected regions with aging. Our proposed DL models named FAG-Net and FGC-Net, which correspondingly estimates biological traits (age and gender) and generates fundus images. FAG-Net can generate multiple variants of an input fundus image given a list of ages as conditions. In this study, we analyzed fundus images and their corresponding association in terms of aging and gender. Our proposed models outperform randomly selected state-of-the-art DL models.<\/jats:p>","DOI":"10.1007\/s40747-023-01141-0","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T04:02:08Z","timestamp":1689739328000},"page":"257-271","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retinal disease projection conditioning by biological traits"],"prefix":"10.1007","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8303-8351","authenticated-orcid":false,"given":"Muhammad","family":"Hassan","sequence":"first","affiliation":[]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[]},{"given":"Ahmed Ameen","family":"Fateh","sequence":"additional","affiliation":[]},{"given":"Shuyue","family":"Ma","sequence":"additional","affiliation":[]},{"given":"Wen","family":"Liang","sequence":"additional","affiliation":[]},{"given":"Dingqi","family":"Shang","sequence":"additional","affiliation":[]},{"given":"Jiaming","family":"Deng","sequence":"additional","affiliation":[]},{"given":"Ziheng","family":"Zhang","sequence":"additional","affiliation":[]},{"given":"Tsz Kwan","family":"Lam","sequence":"additional","affiliation":[]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[]},{"given":"Qiming","family":"Huang","sequence":"additional","affiliation":[]},{"given":"Dongmei","family":"Yu","sequence":"additional","affiliation":[]},{"given":"Canyang","family":"Zhang","sequence":"additional","affiliation":[]},{"given":"Zhou","family":"You","sequence":"additional","affiliation":[]},{"given":"Wei","family":"Pang","sequence":"additional","affiliation":[]},{"given":"Chengming","family":"Yang","sequence":"additional","affiliation":[]},{"given":"Peiwu","family":"Qin","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"1141_CR1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1109\/RBME.2010.2084567","volume":"3","author":"MD Abr\u00e0moff","year":"2010","unstructured":"Abr\u00e0moff MD, Garvin MK, Sonka M (2010) Retinal imaging and image analysis. 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