{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T08:52:14Z","timestamp":1774947134480,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T00:00:00Z","timestamp":1694131200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T00:00:00Z","timestamp":1694131200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"name":"Gerencia Regional de Salud de Castilla y Le\u00f3n","award":["GRS 2275\/A\/2020"],"award-info":[{"award-number":["GRS 2275\/A\/2020"]}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["DTS21\/00158"],"award-info":[{"award-number":["DTS21\/00158"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007515","name":"Universidad de Valladolid","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007515","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Healthc Inform Res"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mixed reality opens interesting possibilities as it allows physicians to interact with both, the real physical and the virtual computer-generated environment and objects, in a powerful way. A mixed reality system, based in the HoloLens 2 glasses, has been developed to assist cardiologists in a quite complex interventional procedure: the ultrasound-guided femoral arterial cannulations, during real-time practice in interventional cardiology. The system is divided into two modules, the transmitter module, responsible for sending medical images to HoloLens 2 glasses, and the receiver module, hosted in the HoloLens 2, which renders those medical images, allowing the practitioner to watch and manage them in a 3D environment. The system has been successfully used, between November 2021 and August 2022, in up to 9 interventions by 2 different practitioners, in a large public hospital in central Spain. The practitioners using the system confirmed it as easy to use, reliable, real-time, reachable, and cost-effective, allowing a reduction of operating times, a better control of typical errors associated to the interventional procedure, and opening the possibility to use the medical imagery produced in ubiquitous e-learning. These strengths and opportunities were only nuanced by the risk of potential medical complications emerging from system malfunction or operator errors when using the system (e.g., unexpected momentary lag). In summary, the proposed system can be taken as a realistic proof of concept of how mixed reality technologies can support practitioners when performing interventional and surgical procedures during real-time daily practice.<\/jats:p>","DOI":"10.1007\/s41666-023-00147-0","type":"journal-article","created":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T13:03:45Z","timestamp":1694178225000},"page":"527-541","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Application of Mixed Reality to Ultrasound-guided Femoral Arterial Cannulation During Real-time Practice in Cardiac Interventions"],"prefix":"10.1007","volume":"7","author":[{"given":"Miguel","family":"Alonso-Felipe","sequence":"first","affiliation":[]},{"given":"Javier Manuel","family":"Aguiar-P\u00e9rez","sequence":"additional","affiliation":[]},{"given":"Mar\u00eda \u00c1ngeles","family":"P\u00e9rez-Ju\u00e1rez","sequence":"additional","affiliation":[]},{"given":"Carlos","family":"Baladr\u00f3n","sequence":"additional","affiliation":[]},{"given":"Julio","family":"Peral-Oliveira","sequence":"additional","affiliation":[]},{"given":"Ignacio J.","family":"Amat-Santos","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,9,8]]},"reference":[{"key":"147_CR1","doi-asserted-by":"publisher","first-page":"2086","DOI":"10.3389\/fpsyg.2018.02086","volume":"9","author":"P Cipresso","year":"2018","unstructured":"Cipresso P, Chicchi-Giglioli IA, Alca\u00f1iz-Raya M et al (2018) The past, present, and future of virtual and augmented reality research: a network and cluster analysis of the literature. Front Psychol 9:2086. https:\/\/doi.org\/10.3389\/fpsyg.2018.02086","journal-title":"Front Psychol"},{"key":"147_CR2","first-page":"0220822","volume":"1237","author":"Y Chen","year":"2019","unstructured":"Chen Y, Wang Q, Chen H et al (2019) An overview of augmented reality technology. J Phys: Conf Ser 1237:0220822","journal-title":"J Phys: Conf Ser"},{"key":"147_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/20539517211063689","volume":"9","author":"B Egliston","year":"2022","unstructured":"Egliston B, Carter M (2022) The interface of the future\u2019: mixed reality, intimate data and imagined temporalities. Big Data Soc 9:1. https:\/\/doi.org\/10.1177\/20539517211063689","journal-title":"Big Data Soc"},{"key":"147_CR4","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/s10055-021-00577-4","volume":"26","author":"Y Gao","year":"2022","unstructured":"Gao Y, Chang C, Yu X et al (2022) A VR-based volumetric medical image segmentation and visualization system with natural human interaction. Virtual Real 26:415\u2013424","journal-title":"Virtual Real"},{"key":"147_CR5","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s10055-021-00583-6","volume":"26","author":"KNK Fong","year":"2022","unstructured":"Fong KNK, Tang YM, Sie K et al (2022) Task-specific virtual reality training on hemiparetic upper extremity in patients with stroke. Virtual Real 26:453\u2013464","journal-title":"Virtual Real"},{"key":"147_CR6","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s10055-021-00550-1","volume":"26","author":"K VanHorn","year":"2022","unstructured":"VanHorn K, \u00c7obano\u011flu MC (2022) Democratizing AI in biomedical image classification using virtual reality. Virtual Real 26:159\u2013171","journal-title":"Virtual Real"},{"key":"147_CR7","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1007\/s10055-020-00481-3","volume":"25","author":"N Garcia-Hernandez","year":"2021","unstructured":"Garcia-Hernandez N, Guzman-Alvarado M, Parra-Vega V (2021) Virtual body representation for rehabilitation influences on motor performance of cerebral palsy children. Virtual Real 25:669\u2013680","journal-title":"Virtual Real"},{"key":"147_CR8","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/s10055-020-00456-4","volume":"25","author":"C Heinrich","year":"2021","unstructured":"Heinrich C, Cook M, Langlotz T et al (2021) My hands? Importance of personalised virtual hands in a neurorehabilitation scenario. Virtual Real 25:313\u2013330","journal-title":"Virtual Real"},{"key":"147_CR9","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s10055-020-00429-7","volume":"24","author":"S Houzangbe","year":"2020","unstructured":"Houzangbe S, Christmann O, Gorisse G et al (2020) Effects of voluntary heart rate control on user engagement and agency in a virtual reality game. Virtual Real 24:665\u2013681","journal-title":"Virtual Real"},{"key":"147_CR10","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1007\/s10055-020-00475-1","volume":"25","author":"C-J Liang","year":"2021","unstructured":"Liang C-J, Start C, Boley H et al (2021) Enhancing stroke assessment simulation experience in clinical training using augmented reality. Virtual Real 25:575\u2013584","journal-title":"Virtual Real"},{"key":"147_CR11","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1007\/s10055-020-00438-6","volume":"25","author":"HI Medellin-Castillo","year":"2021","unstructured":"Medellin-Castillo HI, Zaragoza-Siqueiros J, Govea-Valladares EH et al (2021) Haptic-enabled virtual training in orthognathic surgery. Virtual Real 25:53\u201367","journal-title":"Virtual Real"},{"key":"147_CR12","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s10055-021-00578-3","volume":"26","author":"W Lin","year":"2022","unstructured":"Lin W, Zhu Z, He B et al (2022) A novel virtual reality simulation training system with haptic feedback for improving lateral ventricle puncture skill. Virtual Real 26:399\u2013411","journal-title":"Virtual Real"},{"key":"147_CR13","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1007\/s10055-021-00503-8","volume":"25","author":"Z Zhou","year":"2021","unstructured":"Zhou Z, Jiang S, Yang Z et al (2021) Surgical navigation system for brachytherapy based on mixed reality using a novel stereo registration method. Virtual Real 25:975\u2013984","journal-title":"Virtual Real"},{"issue":"2","key":"147_CR14","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3390\/jimaging8020047","volume":"8","author":"C Uhl","year":"2022","unstructured":"Uhl C, Hatzl J, Meisenbacher K et al (2022) Mixed-reality-assisted puncture of the common femoral artery in a phantom model. J Imaging 8(2):47. https:\/\/doi.org\/10.3390\/jimaging8020047","journal-title":"J Imaging"},{"key":"147_CR15","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s41095-019-0156-x","volume":"5","author":"R Li","year":"2019","unstructured":"Li R, Si W, Liao X et al (2019) Mixed reality based respiratory liver tumor puncture navigation. Comput Vis Media 5:363\u2013374","journal-title":"Comput Vis Media"},{"issue":"6","key":"147_CR16","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.eururo.2021.10.023","volume":"81","author":"F Porpiglia","year":"2022","unstructured":"Porpiglia F, Checcuccia E, Amparore D et al (2022) Percutaneous kidney puncture with three-dimensional mixed-reality hologram guidance: from preoperative planning to intraoperative navigation. Eur Urol 81(6):588\u2013597. https:\/\/doi.org\/10.1016\/j.eururo.2021.10.023","journal-title":"Eur Urol"},{"key":"147_CR17","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2022-018678","author":"T Demerath","year":"2022","unstructured":"Demerath T, Stanicki A, Roelz R et al (2022) Accuracy of augmented reality-guided drainage versus stereotactic and conventional puncture in an intracerebral hemorrhage phantom model. J NeuroInterv Surg. https:\/\/doi.org\/10.1136\/neurintsurg-2022-018678. (Published Online First: 19 July 2022)","journal-title":"J NeuroInterv Surg"},{"key":"147_CR18","doi-asserted-by":"publisher","first-page":"18620","DOI":"10.1038\/s41598-020-75676-4","volume":"10","author":"BJ Park","year":"2020","unstructured":"Park BJ, Hunt SJ, Nadolski GJ et al (2020) Augmented reality improves procedural efficiency and reduces radiation dose for CT-guided lesion targeting: a phantom study using HoloLens 2. Sci Rep 10:18620. https:\/\/doi.org\/10.1038\/s41598-020-75676-4","journal-title":"Sci Rep"},{"issue":"1","key":"147_CR19","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1007\/s00464-019-06755-5.pmid:30911919","volume":"34","author":"CF Davrieux","year":"2019","unstructured":"Davrieux CF, Gim\u00e9nez ME, Gonz\u00e1lez CA et al (2019) Mixed reality navigation system for ultrasound-guided percutaneous punctures: a pre-clinical evaluation. Surg Endosc 34(1):226\u2013230. https:\/\/doi.org\/10.1007\/s00464-019-06755-5.pmid:30911919","journal-title":"Surg Endosc"},{"issue":"11","key":"147_CR20","doi-asserted-by":"publisher","first-page":"913","DOI":"10.3760\/cma.j.cn115259-20200209-00117","volume":"40","author":"D Jing","year":"2020","unstructured":"Jing D, Jing L, Yihan X et al (2020) The application of the virtual reality in training skill of pediatric lumbar puncture by eight-year program students in medical college. Chin J Med Educ 40(11):913\u2013916. https:\/\/doi.org\/10.3760\/cma.j.cn115259-20200209-00117","journal-title":"Chin J Med Educ"},{"key":"147_CR21","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1186\/s12909-022-03317-7","volume":"22","author":"A Vrillon","year":"2022","unstructured":"Vrillon A, Gonzales-Marabal L, Ceccaldi PF et al (2022) Using virtual reality in lumbar puncture training improves students learning experience. BMC Medical Educ 22:244","journal-title":"BMC Medical Educ"},{"issue":"1","key":"147_CR22","doi-asserted-by":"publisher","first-page":"E16","DOI":"10.3171\/2020.10.FOCUS20779","volume":"50","author":"M Schneider","year":"2020","unstructured":"Schneider M, Kunz C, Pal\u2019a A et al (2020) Augmented reality\u2013assisted ventriculostomy. J Neurosurg 50(1):E16. https:\/\/doi.org\/10.3171\/2020.10.FOCUS20779","journal-title":"J Neurosurg"},{"issue":"6","key":"147_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/rcs.2176","volume":"16","author":"XH Su","year":"2020","unstructured":"Su XH, Deng Z, He BW et al (2020) Haptic-based virtual reality simulator for lateral ventricle puncture operation. Int J Med Robot Comput Asist Surg 16(6):1\u201310. https:\/\/doi.org\/10.1002\/rcs.2176","journal-title":"Int J Med Robot Comput Asist Surg"},{"key":"147_CR24","doi-asserted-by":"publisher","unstructured":"Uhl C, Hatzl J, Meisenbacher K et al (2022) Mixed-reality-assisted puncture of the common femoral artery in a phantom model. J Imag 8(2):47. https:\/\/doi.org\/10.3390\/jimaging8020047","DOI":"10.3390\/jimaging8020047"},{"key":"147_CR25","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s41747-017-0033-2","volume":"2","author":"P Pratt","year":"2018","unstructured":"Pratt P, Ives M, Lawton G et al (2018) Through the HoloLens\u2122 looking glass: augmented reality for extremity reconstruction surgery using 3D vascular models with perforating vessels. Eur Radiol Exp 2:2. https:\/\/doi.org\/10.1186\/s41747-017-0033-2","journal-title":"Eur Radiol Exp"},{"key":"147_CR26","doi-asserted-by":"publisher","unstructured":"Tai Y, Wei L, Zhou H et al (2016) Integrating virtual reality and haptics for renal puncture surgical simulator. 2nd IEEE International Conference on Computer and Communications (ICCC), Chengdu, pp. 480\u2013484. https:\/\/doi.org\/10.1109\/CompComm.2016.7924747","DOI":"10.1109\/CompComm.2016.7924747"},{"issue":"7","key":"147_CR27","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.jcin.2010.04.015","volume":"3","author":"AH Seto","year":"2010","unstructured":"Seto AH, Abu-Fadel MS, Sparling JM et al (2010) Real-time ultrasound guidance facilitates femoral arterial access and reduces vascular complications: FAUST (Femoral Arterial Access With Ultrasound Trial). JACC Cardiovasc Interv 3(7):751\u2013758. https:\/\/doi.org\/10.1016\/j.jcin.2010.04.015","journal-title":"JACC Cardiovasc Interv"}],"container-title":["Journal of Healthcare Informatics Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s41666-023-00147-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s41666-023-00147-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s41666-023-00147-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T23:37:38Z","timestamp":1698881858000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s41666-023-00147-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,8]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["147"],"URL":"https:\/\/doi.org\/10.1007\/s41666-023-00147-0","relation":{},"ISSN":["2509-4971","2509-498X"],"issn-type":[{"value":"2509-4971","type":"print"},{"value":"2509-498X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,8]]},"assertion":[{"value":"28 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Approval for this study was obtained from the local ethics committee \u201cComit\u00e9 de \u00c9tica de la investigaci\u00f3n con Medicamentos \u00c1rea de Salud Valladolid Este\u201d in Valladolid (Spain), at its meeting on February 18, 2021.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}