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Recently, showcasing a Broad spectrum of uses like Computational linguistics, image identification, and autonomous systems. With the increasing demand for intelligent systems, it has become crucial to comprehend the different categories of machine acquiring knowledge systems along with their applications in the present world. This paper presents actual use cases of machine learning, including cancer classification, and how machine learning algorithms have been implemented on medical data to categorize diverse forms of cancer and anticipate\u00a0their\u00a0outcomes. The paper also discusses supervised, unsupervised, and reinforcement learning, highlighting the benefits and disadvantages of each category of Computational intelligence system. The conclusions of this systematic study on machine learning methods and applications in cancer classification have numerous implications. The main lesson is that through accurate classification of cancer kinds, patient outcome prediction, and identification of possible therapeutic targets, machine learning holds enormous potential for improving cancer diagnosis and therapy. This review offers readers with a broad understanding as of the present advancements in machine learning applied to cancer\u00a0classification today, empowering them to decide for themselves whether to use these methods in clinical settings. Lastly, the paper wraps up by engaging in a discussion on the future of machine learning, including the potential for new types of systems to be developed as the field advances. Overall, the information included in this survey article is useful for scholars, practitioners, and individuals interested in gaining knowledge about\u00a0the fundamentals of machine learning and its various applications in different areas of activities.<\/jats:p>","DOI":"10.1007\/s44230-023-00041-3","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T03:08:46Z","timestamp":1694401726000},"page":"588-615","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":115,"title":["Applications and Techniques of Machine Learning in Cancer Classification: A Systematic Review"],"prefix":"10.1007","volume":"3","author":[{"given":"Abrar","family":"Yaqoob","sequence":"first","affiliation":[]},{"given":"Rabia","family":"Musheer Aziz","sequence":"additional","affiliation":[]},{"given":"Navneet Kumar","family":"verma","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,9,11]]},"reference":[{"issue":"1959","key":"41_CR1","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1147\/rd.33.0210","volume":"3","author":"AL Samuel","year":"1959","unstructured":"Samuel AL, Gabel F. 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